Basic Information

Insect: Timema podura
Gene Symbol: Zfhx4
Assembly: GCA_033556935.1
Location: JAVRXN010000005.1:38390360-38408511[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.24 46 6.5 0.1 2 23 312 334 311 334 0.91

2 8 0.00018 0.035 16.3 1.8 2 23 628 650 627 650 0.95

3 8 4.5e-05 0.0087 18.2 0.7 1 23 682 706 682 706 0.92

4 8 0.0066 1.3 11.4 0.4 1 22 777 798 777 801 0.91

5 8 4.2 8.2e+02 2.6 0.9 2 20 1019 1037 1018 1042 0.92

6 8 0.75 1.4e+02 5.0 1.2 1 23 1070 1094 1070 1094 0.91

7 8 0.1 20 7.7 0.5 1 23 1177 1200 1177 1200 0.95

8 8 0.034 6.5 9.2 0.0 1 23 1220 1243 1220 1243 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.24	46	6.5	0.1	2	23	312	334	311	334	0.91
2	8	0.00018	0.035	16.3	1.8	2	23	628	650	627	650	0.95
3	8	4.5e-05	0.0087	18.2	0.7	1	23	682	706	682	706	0.92
4	8	0.0066	1.3	11.4	0.4	1	22	777	798	777	801	0.91
5	8	4.2	8.2e+02	2.6	0.9	2	20	1019	1037	1018	1042	0.92
6	8	0.75	1.4e+02	5.0	1.2	1	23	1070	1094	1070	1094	0.91
7	8	0.1	20	7.7	0.5	1	23	1177	1200	1177	1200	0.95
8	8	0.034	6.5	9.2	0.0	1	23	1220	1243	1220	1243	0.92

Sequence Information

Coding Sequence: ATGCCTACCCCCACCTCCGGGGCGCCGCTAGTGGAGCAACAGGAGGGCTCCAGCCGCAGGAAGAGGAAGCGCAAGAGGGAGGACGACGACGACCACCACCACGAGGACGACGACATGAGTCCAGAGGAAGAGGCGTCCGCTTCGCCGCCGGCCGCGGTCATCGCGGGTGGCAGGGAAGACGACGACCAGCGCCGCATGTCTTCGCCGCCCTCGGAAGCAAGTTCCTACACGACGAGGTCCTTCCTATCACCAGGATCACGGAGGATGGCGTCGACGACCCACAGAGACGAGGAAGAAGACGCGGCGTCATCCGGGTGTTCCGACGACGAAACGACGAGTAGGCAGCACCAGTCGGGGAGTAAGGTGAAAACGAAAGAAGGTAGCCGTGATATCGAGAGGCCTCGGAACTTCGTCCCAGTCGTGGAAGATTCTCTAGGCACCAGCAGTGACGTGGAGAAGTTTGACGGGAAGATCGTATACAACCCGGATGGCTCGGCTTACATCATCGAGGATAGCGAGATGAGTGAAGAGGACACGGGTCTCGAAGTCCTGCCGAGGATCATCGGTGATGGCTGCATCGTGGATGGTCGTGGCGTCAGCCTCCCCCATCTGCAGTCCTTCCCGCAGATCGCCAACGCGTTTTACGTGTCGAGGAATCCTTCCCTCTACAACGCCCTCTACGGCGGTACAGCGAGCTACTCCAATAACCTCTTGCAAGACAAGAAAATAGTTCCTGAAGTTCCAATCATGCACAGTTACAGGGTCTATACGGTTCGTGATAGTAAAAGTGGTGATAGTGAAGACGGTAAGATGTACGACGCGGCCGGCCGCGGGGACTGTGATGGCAGGAAGCCTGAGATCTCGGAGAAGAAGGTGAAGAGCGACAAATTCTCCGGGAAAGACTGTTCCTCAGTGCCCGTAAAGCCCATCCTCATGTGCTTTATATGCAAATTGTCGTTCGGCTACGCCAAGTCGTTCGTGGCGCATGCTATGGGTGACCACAATGTGGCCCTCCTCGAAGACGAGAAGGACATCCTCGGGCACAAGAACGCCTCTGCCATCATCCAGTGCGTGGGAAAAGACAAGGAGCCGCTCGTATCGTTCCTCGAACCCTTGTCCCCTGGGGTTAGCACCTTGGGTGACGCGGGTAAGAGGGTGGTCAACCCAGTGGCGCCGCCTCTTAGCGAGGCGGACATGAATAACCTTATGGCGGCGGCCGGGATCACATCCACCGCCGTCTCGCAGTTAGTTCCTAAGGACCAGCAAGTGTCGTACGCCGTCGGTGGCGGTGGTGACGAGTGCGCGGGTGCGGATAAGAAGGCGGTCGACAGCATCGAACCGGAGAGCCTAGTAGTCCACCGCCGGCATACACTAGACTGTGGCACCGGGAGCGGCATCGCTCCCATGGGGCGACCCAACGTCCAGAATATACATGTTCCTGAGACTTCGGTCTCCCTACCTCAAAATTGTGGTAGTtctagtaatagtagtaataatcacaataattgtaatagtaatagtagaaTGATTGGTATCGGTATGAACAGTGTGATGGACCTGACCAGGAAAAGTCCCATATCGGCGTCGGCAGCGTCGTCCGGCAACAACGGCCGTGGCAGCGTCTCCCCCGGCGCCAGCCCTTCCCCCGGCTCTACGTTGAGCCCACTACTCACAGGAGTGGGGCCCACTGGACCCCTCCAATACCCGCAACCCCCGCCCAACTTCCTGACGGGCACGACGATAGGGGTGTGCCCTGACCACATGGGTGGACGCCCCAGTGGCGTTGAGTGCGCCAAATGTGAACTGATCCTTAACTCGTCCCGACTGGGTGGGGGTGGTGTCTTGGCCGGTATGCACTCTAGAAACTCGTGCAAGACACTCAAGTGCCCCAAGTGCAATTGGCACTACAAGTACCAGGAGACTCTCGAAATACATATGAAGGAGAAACATCCGGAGGCGGAGACATCGTGCATCTACTGCATCGCGGGTCAGCCGCACCCCAGGCTGGCCAGGGGCGAAACATACACGTGTGGATACAAACCCTACCGCTGCGAGGTATGTAACTACTCCACGACCACCAAAGGCAACCTCAGCATACACATGCAATCCGACAAACATCTCAACAACATGCAGGAGCTACAGAATGGTGGTGGGACAATGCCACCTACGTCTGAGCCTTCAGGCATATCAGGCCCTCCCCCCTCGACACAGCCTCCCCACCACGGCAAGTCCCCCGGGCCGGGGGTGGGTATGATGAGTCCCGGGGGCGCTTCTCACCCGCAGCACTCGCACCACCAGATGGTGCAGAGTCAGAAACCTAAACCAACATTCCGCTGCGACGTGTGCAACTACGAGACGAATGTAGCCAGGAATCTAAGGATCCATATGACGAGcgagaaacacacacacaacatgaTGGTGCTCCAGCAGAACGTGAAGCACATGCAGACGCTGTCGGCCTTGCACCAACAGTCCCAACAACATCAGCAACACCAACACCAGCAGCAGTTGAGTTTCGAGTCTCTTCTCCACTTCCACCCGGGGCTCACTCTGCCGGGAGACAAGCCCCCTCCGCACACGGAGGCGGCCCTTGCCGACATGGCATACAACCAGGCCCTCCTCATACAGATGATGACTGGGGGCCAGCTACCGCCACACATTCCCCCGGAACTAGCCCCTCATATGGACATGGGGTTGAACCCGGAGACGATGGAACCTCCACCGGAACCCGCCGACCCAAACCCTCAACACCTGTTCCAGTGCTGCGTCTGCAATATCTTCTCGACGGACTCGTTGGAGGCGTTGAGTCACCACCTATCCGCGGATAGGACAAAGACGAGAGAGCAGGAGATACTGGCGGTGGTCGCGGGCCACTACGTCTGCAGACTTTGCACGTACAAGACGAACCTGAAGGCCAACTTTCAGCTGCATTGCAAGACGGACAAACACCTTCAGAGGCTACAGCACGTGAACCACGTCAAAGAAGGTGGCCCCAGGAACGAGTGGAAATTGAAATACGTGTCGTCGTCGTCGGCCGCGGGAGGTATACAAGTCCGGTGCCACGCATGCGACTACTACACCAACAGCGCCCACAAGCTCCAGCTGCACGCGGCCGGGCAGAGGCATGAAGCGTCCTGCCTCCTCTTCCTCCACCTCAGAGACTGCGAGTCGAGTCTTGGCGGTAGTGGAAGTAGCGGTGACAGGGTCTACCACTGCGCGCTCTGCGGGTTCTCTAGCAGGGCGAAACTGCAGCTGCTGCAGCACGTCAGGTCGATGAAACATCTTCAAATGGAACAGCTTCATCAGCTGCAGAGGAGGAGTGAGGGGAAGGACCTCCACACGGACATCGGCGAGGTTTTCCAGGTCATCGGGCAGGAGCACGCCTTCAGTGATATGACGGACCCGGACCCCCGCAAAGACCACCAACAACAGCGCCAGCAGTTGTCCAACAGGGAGCAGCAACACCATATCGAGAAGTCGGAGCAGGAACCGGAAGACACCATCATGACCAACTCTTCCAACCACCAACACATGTGCCCCTACTGCAACTACACGAGTAGCTCAGAGATGCGCATCCAGGCACACGTTCTCACCGCGCACGGTCATTCAGAGCCGTCGCCTCCTCCTCCCGCGAGGGCCTCTTCGCCCATCAAAGACTTCCTATGCCCTCTTTGTCAGGATGGATTCCGGGACCGTGCGCAGCTCGAGGTCCACGTCATGCAGATCCACAGCGTCAACAGCGAAGGTCTCCAAAGGTTGCTGCTACTGGTGGACCAGTCCCACTGGCTGAACGCCGTCAGTAGATCGTCGGCCCCTTCCACCCCACAATCTCAACCGACACCCCACCACCCCCAACACCATACACCTCCCGGATCCAACTCTCACCCCCATCACAACCAGATGATCTCACCCTCCTCCAGCTCGGCCGGATCCTCCAAAGAACTCGACTCCAGTGGGGGTAAACAGAACAACTCTGACGTAAACTCCATAGAGGACCGTGAAGATCACTCCCATCCGGACCTCATGTCCCCGTCTCCCGATGATCAGAGTGACGCGGATGAGAACCGTTGCCAGACGTGCTTCAAAGCTTCAGAAATATCGATGAACTATGCGCTCACCAGAACGAGACTGGTCACCTTGAGATTAAGCAAACTCCGTCTGGGCCAGGCTATCTCTGTTGGAAGAAAGGGTGCAACCAGTATTTTCCGACGGCTCATAGTTTACAAATGCACTTCAGGGAGATACATTCCTCTAGAAGCTCAGGACTGA
Protein Sequence: MPTPTSGAPLVEQQEGSSRRKRKRKREDDDDHHHEDDDMSPEEEASASPPAAVIAGGREDDDQRRMSSPPSEASSYTTRSFLSPGSRRMASTTHRDEEEDAASSGCSDDETTSRQHQSGSKVKTKEGSRDIERPRNFVPVVEDSLGTSSDVEKFDGKIVYNPDGSAYIIEDSEMSEEDTGLEVLPRIIGDGCIVDGRGVSLPHLQSFPQIANAFYVSRNPSLYNALYGGTASYSNNLLQDKKIVPEVPIMHSYRVYTVRDSKSGDSEDGKMYDAAGRGDCDGRKPEISEKKVKSDKFSGKDCSSVPVKPILMCFICKLSFGYAKSFVAHAMGDHNVALLEDEKDILGHKNASAIIQCVGKDKEPLVSFLEPLSPGVSTLGDAGKRVVNPVAPPLSEADMNNLMAAAGITSTAVSQLVPKDQQVSYAVGGGGDECAGADKKAVDSIEPESLVVHRRHTLDCGTGSGIAPMGRPNVQNIHVPETSVSLPQNCGSSSNSSNNHNNCNSNSRMIGIGMNSVMDLTRKSPISASAASSGNNGRGSVSPGASPSPGSTLSPLLTGVGPTGPLQYPQPPPNFLTGTTIGVCPDHMGGRPSGVECAKCELILNSSRLGGGGVLAGMHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPEAETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGGTMPPTSEPSGISGPPPSTQPPHHGKSPGPGVGMMSPGGASHPQHSHHQMVQSQKPKPTFRCDVCNYETNVARNLRIHMTSEKHTHNMMVLQQNVKHMQTLSALHQQSQQHQQHQHQQQLSFESLLHFHPGLTLPGDKPPPHTEAALADMAYNQALLIQMMTGGQLPPHIPPELAPHMDMGLNPETMEPPPEPADPNPQHLFQCCVCNIFSTDSLEALSHHLSADRTKTREQEILAVVAGHYVCRLCTYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGPRNEWKLKYVSSSSAAGGIQVRCHACDYYTNSAHKLQLHAAGQRHEASCLLFLHLRDCESSLGGSGSSGDRVYHCALCGFSSRAKLQLLQHVRSMKHLQMEQLHQLQRRSEGKDLHTDIGEVFQVIGQEHAFSDMTDPDPRKDHQQQRQQLSNREQQHHIEKSEQEPEDTIMTNSSNHQHMCPYCNYTSSSEMRIQAHVLTAHGHSEPSPPPPARASSPIKDFLCPLCQDGFRDRAQLEVHVMQIHSVNSEGLQRLLLLVDQSHWLNAVSRSSAPSTPQSQPTPHHPQHHTPPGSNSHPHHNQMISPSSSSAGSSKELDSSGGKQNNSDVNSIEDREDHSHPDLMSPSPDDQSDADENRCQTCFKASEISMNYALTRTRLVTLRLSKLRLGQAISVGRKGATSIFRRLIVYKCTSGRYIPLEAQD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01451113;
90% Identity: iTF_01445297;
80% Identity: -