Basic Information

Insect: Timema podura
Gene Symbol: PRDM1
Assembly: GCA_033556935.1
Location: JAVRXN010000010.1:65536699-65546258[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 2e-05 0.0038 19.4 2.5 1 23 540 562 540 562 0.99

2 5 7.7e-06 0.0015 20.6 4.9 1 23 568 590 568 590 0.98

3 5 1.2e-06 0.00024 23.2 4.3 1 23 596 618 596 618 0.98

4 5 0.00078 0.15 14.3 1.5 1 23 624 646 624 646 0.97

5 5 0.02 3.8 9.9 0.3 1 17 652 668 652 669 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	2e-05	0.0038	19.4	2.5	1	23	540	562	540	562	0.99
2	5	7.7e-06	0.0015	20.6	4.9	1	23	568	590	568	590	0.98
3	5	1.2e-06	0.00024	23.2	4.3	1	23	596	618	596	618	0.98
4	5	0.00078	0.15	14.3	1.5	1	23	624	646	624	646	0.97
5	5	0.02	3.8	9.9	0.3	1	17	652	668	652	669	0.94

Sequence Information

Coding Sequence: ATGCCGgTGTACAAAGACAATGAGTTGTTCTACTATATGGACGGCTATGACACGAGAAAAGCCAACTGGATGCGTTTTGTTAACCCGGCCTACTCATCTGAATCTCAGAACCTCATAGCATGTCAATACAAGATGAATATTTACTTCTACACAATCAAACCAATCTTGCCAAACCAAGAACTTCTTGTTTGGTATTGCCGAGAATTTGCCGAACGTCTCAATTACCCACTGACTGGAGAACTTATGCTGCAAAGAATAAGACAACAGGTACAACAGTCAACGGCAGTGAGTGCACCAGTATCGAGTACATCTGCCAGGTGCTCTGAGACTTCATTGCCTGTGGTAGCAACAGAACCCTCTGGGGATTCCCCCAGCAAAGATCCACCTCCCCACCACCATGTCTATGATGCTCGTCCCACCACACTTACCCCACCAGATGGCTCTGTTAGATCAGACGAAGGATATCACAGTAATGGCTACCACGATGATGGCTTTACTCCTCCAGAAGATAGTAGTGACTCTGACAGTGAAAACAATTATGTTCTTGATTTCAGCAAAAAGCCTGCAGATGATGAAGCAGCTGTTATCATTGAACCACCAGATGTTCAAAAGAATGAGTATCGCAAAGTAAAGATCAAGATCACAAAAGCTTATCACTACAAAGTCAAATCTGAAAACTTGGAGAACACCTCCAAAAATGATAAAGACACGATAGTTCCTGAGCCTACAGCAACACCATTACCTATCTCTTCTCCCCCAAACAGTACCACCTTGATCGTTATTGACTCTCCTCCTCCACCACCCACAATGGCTCCAATCCAGAAACCTTACTATGAACCTGAAGTTGTCAATACTATTAACAGGCACAGCCCACCTACAACAagcatattagaaaatattttaactaggaacaggacagacacaaataatAACAGAGAAACACATAAACACAGACAACCAGATTCTACGCCACCACCTTCATCCCCCACAGAGATGGCATATTCTTACAAGAAGTCTCATCGCTATACTGCCGTTCCGTGTAGCCCAGACTCTAGTTCAAGTACTCCTCAACCTTCCATTCAACTTCTTCCCCCTAATATTCCTCAATCTTCATCACAGCCGAATCAGAATACTCACCTCTTACTTCCCTCTATGCCTTTGAATCGACCTTCCCTCCACGCCTCTCGTACCCCTTCCCCTCAACCTATAATATATTCCAATCACTATCACCACTCCTCCATCACTCATCCTGAGATTACTTATCTCAATAATGGTCCTCCAGTATTTAACAACCACCCTCCTTACCCATACAACCTTTATCCACCTCCAAATGGTACATTAATTAACCACCAATCTCCTCCAACAAATGTTTCCACTTCATCGTATTCCCCACCTCTCTTAACAAATGTTCCTTCTATGATAAGTCTTCAGAACACATCTCCAAACAACCTTCACCTGAGTCATCATTTGCTTACACCACTATCCCCACGCAGATCTTCTCCATTAAGTTCGTCTTCTCCAGAGGGTGGCTCCTGCCCTACCAGCCCAAACAGTCAGGGCTCTAGGGGTTACCGTTCGTTACCCTATCCCCTCAAGAAGAAGGATGGAAAGATGCACTATGAGTGCAATGTTTGCTGCAAAACATTTGGCCAACTATCCAATCTTAAAGTTCACCTGCGCACTCACTCTGGGGAGAGGCCATTCCGATGTAATGTGTGTACAAAAAGTTTCACACAGTTGGCTCACCTACAGAAACACCATCTAGTACATACAGGTGAGAAACCCCATCAGTGTGACATCTGTAAAAAGCGATTCAGCTCCACGTCCAACCTGAAAACTCACTTGAGGCTCCACTCGGGCCAAAAGCCGTATGCATGTGACCTTTGTCCAGCCAAATTCACGCAGTTTGTCCACTTGAAACTTCATAAGAGGCTGCACACGAATGAACGACCCTACACATGCCAGGGCTGCAATAAGAAGTACATCAGTGCTAGTGGACTAAGGTATTTATAG
Protein Sequence: MPVYKDNELFYYMDGYDTRKANWMRFVNPAYSSESQNLIACQYKMNIYFYTIKPILPNQELLVWYCREFAERLNYPLTGELMLQRIRQQVQQSTAVSAPVSSTSARCSETSLPVVATEPSGDSPSKDPPPHHHVYDARPTTLTPPDGSVRSDEGYHSNGYHDDGFTPPEDSSDSDSENNYVLDFSKKPADDEAAVIIEPPDVQKNEYRKVKIKITKAYHYKVKSENLENTSKNDKDTIVPEPTATPLPISSPPNSTTLIVIDSPPPPPTMAPIQKPYYEPEVVNTINRHSPPTTSILENILTRNRTDTNNNRETHKHRQPDSTPPPSSPTEMAYSYKKSHRYTAVPCSPDSSSSTPQPSIQLLPPNIPQSSSQPNQNTHLLLPSMPLNRPSLHASRTPSPQPIIYSNHYHHSSITHPEITYLNNGPPVFNNHPPYPYNLYPPPNGTLINHQSPPTNVSTSSYSPPLLTNVPSMISLQNTSPNNLHLSHHLLTPLSPRRSSPLSSSSPEGGSCPTSPNSQGSRGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLRTHSGERPFRCNVCTKSFTQLAHLQKHHLVHTGEKPHQCDICKKRFSSTSNLKTHLRLHSGQKPYACDLCPAKFTQFVHLKLHKRLHTNERPYTCQGCNKKYISASGLRYL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01448988; iTF_01446027; iTF_01451013; iTF_01447944; iTF_01447018; iTF_01445172;
90% Identity: iTF_01447018; iTF_01448988; iTF_01446027; iTF_01451013; iTF_01447944; iTF_01445172;
80% Identity: iTF_01447944;