Basic Information

Insect: Timema monikensis
Gene Symbol: ZFHX3
Assembly: GCA_902151445.1
Location: CABFVZ010001307.1:156059-159706[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.1 21 7.9 0.5 1 23 50 73 50 73 0.95

2 11 0.033 6.8 9.4 0.0 1 23 93 116 93 116 0.92

3 11 0.073 15 8.3 1.9 2 22 229 249 229 252 0.90

4 11 0.1 21 7.9 1.1 3 23 266 289 264 289 0.88

5 11 0.0075 1.5 11.5 1.7 1 23 311 333 311 333 0.97

6 11 0.0019 0.39 13.4 0.9 2 23 340 362 339 362 0.96

7 11 0.00043 0.09 15.4 3.9 1 23 475 499 475 499 0.92

8 11 0.0052 1.1 12.0 0.6 1 22 519 540 519 543 0.89

9 11 0.00069 0.14 14.7 0.2 1 23 606 630 606 630 0.93

10 11 0.093 19 8.0 0.2 2 21 775 794 774 795 0.93

11 11 0.52 1.1e+02 5.7 1.6 2 19 937 954 936 959 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.1	21	7.9	0.5	1	23	50	73	50	73	0.95
2	11	0.033	6.8	9.4	0.0	1	23	93	116	93	116	0.92
3	11	0.073	15	8.3	1.9	2	22	229	249	229	252	0.90
4	11	0.1	21	7.9	1.1	3	23	266	289	264	289	0.88
5	11	0.0075	1.5	11.5	1.7	1	23	311	333	311	333	0.97
6	11	0.0019	0.39	13.4	0.9	2	23	340	362	339	362	0.96
7	11	0.00043	0.09	15.4	3.9	1	23	475	499	475	499	0.92
8	11	0.0052	1.1	12.0	0.6	1	22	519	540	519	543	0.89
9	11	0.00069	0.14	14.7	0.2	1	23	606	630	606	630	0.93
10	11	0.093	19	8.0	0.2	2	21	775	794	774	795	0.93
11	11	0.52	1.1e+02	5.7	1.6	2	19	937	954	936	959	0.91

Sequence Information

Coding Sequence: atgtattttaatgtttctccCACAGACCCCCGCAAAGACCACCAACAACAGCGCCAGCAGTTGTCCAACAGGGAGCAGCAGCACCATATCGAGAAGTCGGAGCAGGAACCGGAGGACACCATCATGACCAACTCTTCCAACCACCAACACATGTGCCCCTACTGCAACTACACGAGTAGCTCAGAGATGCGCATCCAGGCACACGTTCTCACCGCGCACGGTCATTCAGAGCCGTCGCCTCCTCCCCCCGCGAGGGCCTCTTCGCCCGTCAAAGACTTCCTATGCCCTCTTTGTCAGGATGGATTCCGGGACCGCGCGCAGCTCGAGGTACACGTCATGCAGATCCACAGCGTCAACAGCGAAGGTCTCCAAAGGTTGCTGCTACTGGTGGACCAGTCTCACTGGCTGAACGCCGTCAGTAGATCATCGGCCCCTTCCACCCCACAATCTCAACCGACACCCCACCACCCCCAACACCATACACCTCCCGGATCCAACTCTCACCCCCATCACAACCAGATGATCTCACCCTCCTCCAGCTCAGCTGGATCCTCCAAAGAACTCGACTCCAGTGGGGGTAAACAGAACAACTCTGACGTAAACTCCATAGAGGACCGTGAAGATCATTCCCATCCGGATCTCATGTCCCCGTCCCCCGATGATCAGAGTGACGCGGATGAGAACCGTTGCCAGACGTGCTTCAAACTCTTCAGAAATATCGATGAACTGTGCGCGCACCAGAACGAGACTGGTCACCTTGAGATTAAGCAAACTCCGTCTGGGCCAGGCTATCTCTGTTGGAAGAAAGGGTGCAACCAGTATTTTCCGACGGCTCATAGTTTACAAATGCACTTCAGGGAGATACATTCCTCTAGAAGCTCAGGACTGACGCAGCAAGGTATGGCGGTCTCTGAGAAACATGTATACAAGTACCGGTGCAATCAATGCAGTCTGGCGTTCAAAACGATGGAAAAACTTCAGCTCCATTCCCAATATCACCTTATAAGAGATGCCACCAAGTGTGTCCTCTGTGGTAGAAGCTTCAGGTCCGTCATTGCTTTGCATAAACACGTGGAAACCTCTCACGCAGAACTGACCGATGAAGAACTAGCAGCTTACAAACAGAGCTTGATGAATAACCCTTTGTTACTAGCCGGTTTCAGTGGACAAGTCCTTGACCCGTCGACGAACGAATTGCTCAAGAAAGAGAGCCTCAAGATGGACTCTGATGACTTGATAGATACGGATGAGAGTCCAACCAAAGACCACTCGCACAATCAGGATGACGGGTTGGGAAACTCTCACAGCGGGGATGGGGAGAACAGTGATGACTCGGTGGTGTACAAAGAGCAGCAGTTCCTAGAGGATTACCTCAACAGCCAGGCCATCGCCGAGGATAGTTACAACGACCCTAACCGCAAGTACAAGTGTCACAGGTGCAAAGTTGCTTTCACAAGACAGAGCTACCTAACAAGTCACAACAAGACGCTCCTGCATCGTAAAGGAGAAAAGTTGAGCTACCCCATGGAGAAATATCTCGACCCCAACAGACCTTACAAGTGCGACGTATGCAAAGAATCCTTCACTCAGAAAAACATTCTTCTGGTTCATTACAACTCTGTAAGTCATCTTCATAAACTCAAGAGAGCGATGCAGGAACAACAACAacatcataataataacaataataataataatggtgcgACATCTGTTTCTCCCGTCTCCGCAGCGGCAGCTCTTGCTGCAAGCTTGGGAGTAACGCCTCCGCCAACCCCAAAATCCAGCAACATCTTGGATGATGATGACAAGAAACCTTACAAGTGTAACATCTGCAAAGTGGCTTATAGCCAAGGTTCCACTTTAGACATCCACATGAGGTCAGTTCTTCATCAGACCCGAGCATCCAAGCTCCAAGATCTCGCCATTAGCGGTCAGATTGATCTGAGCAAGCCTCTAATAGAGCAACCCGAGCCTCAGAAGATCCAAGACCAGCACAAGAAGATGCTTCAGGACATTCTAGGGACGTCCCCTAAACAGACGACGACGTCGCCAAGCTCCGGCGTGAACACGAGCAGCAGCAGCGTGACTTCGCAAGTGCCGTCTCTAGCCCAGGGGTCTCCTCCCGTCACGGGCAGTCATATAGTTCCTCAATCGTCTAGCGCTGCCGCTGTATCGGCTTCGACACCGACCATGACTTCAGTTCCTAGTAGCGTTATGCCTAACAACGCCACGACACCTAACTCGAGTACAACAAGCCACATCAACAACGCTCAAGTGCCGCCTGTGATAGCATCATCGCCCTCCCCCCAGCACGGAATGCTCTCCTGCCAGAGGTGCAGTGCCCTTTTCGCCAACCAAGAGCAGCTGACCACGCATCAGCAGCTCTACTGTCTCTTCGGCAGTCCAATGAATATCTTCCCTCCTCTGCCCACGCCAACTCAGGCGTCTACCCAGACCCACCCTTCCCATTGCTCTCCTCAACCCTTGGGCCACAAAACACCCCCTCCGGTGTCCACGACCCCTCACCTTCAAGACGACCCTTTTCCTAGAGTGTCTGTGGGGAACAAGAAGCCCTCGCAAGTGTACAAACATCTTCTCGAGAGCTTCGGTTTCGATCTGGTCATGCAGTTCAACGAGAACCACCAGAGACGGCAAAGGAAAGAGAGGGAGGAAGAGAACGAAGCCCCTCCTCCGCCGATGCCGAGCTCCCTGACGCCACAACAGCCCGAAACCCAACCGGAAGGCGTTGTCGTGAAAATCGAGGTGGAAGACGTCCCTGAGCAAGATCTTCCAGAAGTGGCAAAGTCTGTGTGTCAGCATTGCCGAAAGGAGTTCTCCAGCGTGTGGGTTCTCAAAGCTCACTGCGAGGAGGTCCACAGAGACTTGGTACCCCCAGAGTTCCTTGAGAAATACGCGCAGCAGATCAAGTCAGAATACGAGAAGAAAGGGGCGAACGCCTCAGGGGCGCCCAGCGTTCCAGGACCTGTGATCCAGATCTCGACGAGCAGCAACACCGACGCTGTCCCCGAGAAGGAACCCGAAGACAACAAAGAAGCGCTACACGCCAAAATGGGTTTGAGCCAACCCCAACAGCATAACCACCACCGGCAGGCCACTCCGCCCGTGAGGACGCCGCCCGCGCCTAGTACGCCCACGGCGTCGTCCACACCAGCGTCCAGCACCGATTCAATACCGGCGACGCTCTCAACGCCCATGGCCGTCTCGATGATGGGCTCCGCCAACAACGTTGCGTCCGGCAACCCCCAGAGCCTGTCCATGTCGCTGGCGCAGCAGATGAACGAGATGCAGGCGGCATTGAACGTCATGGCGGCGTCTCAGCTCCAACAGCAGCTGCAGCAGTTCAACCCTATGATGATGGGGATGGCAGGGCTTGGGATGGGGCTTCCCCTGGGGCTCAATATGAACGCTCTGGCGGCGATGAACCTCCAGCCGCCCCTGGTGCCAATGATGATGCCGCCCCCACCCTTCGACACGATGAGTCTAGCGCAGGCGCAGAGCCCGCTGTTCTCACCGCAGGGCGGAGGCATGGACCATACATCCCTGCTTGCTAAGCAACAGCAACACCTCCTCCAACAGCAACAGCAGGCGGTGAGTATCTCGGATAAGTTTAGAGTGGATGTAAACTGA
Protein Sequence: MYFNVSPTDPRKDHQQQRQQLSNREQQHHIEKSEQEPEDTIMTNSSNHQHMCPYCNYTSSSEMRIQAHVLTAHGHSEPSPPPPARASSPVKDFLCPLCQDGFRDRAQLEVHVMQIHSVNSEGLQRLLLLVDQSHWLNAVSRSSAPSTPQSQPTPHHPQHHTPPGSNSHPHHNQMISPSSSSAGSSKELDSSGGKQNNSDVNSIEDREDHSHPDLMSPSPDDQSDADENRCQTCFKLFRNIDELCAHQNETGHLEIKQTPSGPGYLCWKKGCNQYFPTAHSLQMHFREIHSSRSSGLTQQGMAVSEKHVYKYRCNQCSLAFKTMEKLQLHSQYHLIRDATKCVLCGRSFRSVIALHKHVETSHAELTDEELAAYKQSLMNNPLLLAGFSGQVLDPSTNELLKKESLKMDSDDLIDTDESPTKDHSHNQDDGLGNSHSGDGENSDDSVVYKEQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTSHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQQHHNNNNNNNNGATSVSPVSAAAALAASLGVTPPPTPKSSNILDDDDKKPYKCNICKVAYSQGSTLDIHMRSVLHQTRASKLQDLAISGQIDLSKPLIEQPEPQKIQDQHKKMLQDILGTSPKQTTTSPSSGVNTSSSSVTSQVPSLAQGSPPVTGSHIVPQSSSAAAVSASTPTMTSVPSSVMPNNATTPNSSTTSHINNAQVPPVIASSPSPQHGMLSCQRCSALFANQEQLTTHQQLYCLFGSPMNIFPPLPTPTQASTQTHPSHCSPQPLGHKTPPPVSTTPHLQDDPFPRVSVGNKKPSQVYKHLLESFGFDLVMQFNENHQRRQRKEREEENEAPPPPMPSSLTPQQPETQPEGVVVKIEVEDVPEQDLPEVAKSVCQHCRKEFSSVWVLKAHCEEVHRDLVPPEFLEKYAQQIKSEYEKKGANASGAPSVPGPVIQISTSSNTDAVPEKEPEDNKEALHAKMGLSQPQQHNHHRQATPPVRTPPAPSTPTASSTPASSTDSIPATLSTPMAVSMMGSANNVASGNPQSLSMSLAQQMNEMQAALNVMAASQLQQQLQQFNPMMMGMAGLGMGLPLGLNMNALAAMNLQPPLVPMMMPPPPFDTMSLAQAQSPLFSPQGGGMDHTSLLAKQQQHLLQQQQQAVSISDKFRVDVN*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01450364; iTF_01450972;
90% Identity: iTF_01450364;
80% Identity: -