Tmon002706.1
Basic Information
- Insect
- Timema monikensis
- Gene Symbol
- -
- Assembly
- GCA_902151445.1
- Location
- CABFVZ010000054.1:876796-877866[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0035 0.72 12.5 0.1 3 23 43 63 42 63 0.96 2 11 2.3e-05 0.0048 19.3 2.4 1 23 69 91 69 91 0.98 3 11 8.2e-07 0.00017 23.9 2.2 1 23 97 119 97 119 0.98 4 11 0.00024 0.049 16.2 0.5 1 23 125 147 125 147 0.98 5 11 2e-05 0.0042 19.5 1.3 1 23 153 175 153 175 0.97 6 11 1.8e-05 0.0037 19.7 0.9 1 23 181 204 181 204 0.97 7 11 1.2e-05 0.0025 20.3 0.6 1 23 214 236 214 236 0.97 8 11 2.2e-05 0.0046 19.4 0.6 1 23 242 264 242 264 0.95 9 11 1.3e-06 0.00026 23.3 1.4 2 23 271 292 270 292 0.96 10 11 4.3e-05 0.0089 18.5 5.8 1 23 298 320 298 320 0.96 11 11 8.9e-06 0.0018 20.7 0.4 1 23 326 348 326 348 0.98
Sequence Information
- Coding Sequence
- ATGTCAAGTAAATCGAAAAGGAAAGTACGGAAAGGAAAGTCGAATCGTAAAGTTCCTGGGGAAATGTCTAACACATGCAAGTTGGACATTCATGAAATGTTCAACGAATCAGCTTCCCCCGACTTGTGTCCTCCATGCGATACAACCTTCAACAGTAAAAGAGAAATTGAAGCACACTTAAGACTCCACGCGAATCCTACAGAGTTTGTTTGTGAACACTGCAACAAAGTATTTACAGCAAATAAACGGTTGGTAAACCATCTTAAAACACACAGCAAGGACCGCCCTTATTCCTGTGACATATGCAACAAGTCATACAAGCGTAGATACGAACTGACAATGCACAAGAGGATCCATACAGGCCTAAAAAGCTTCATCTGTAATATCTGTGGGTATGCTACGATGTACAAAGGGTACCTCAATATCCATTATAAAAGGCATTTAAACCAATTTAGGTTTAggtgtaatatttgtaaaaaagggTTCTACACAAACTTTGAACTTCAAGTCCATAACAATGTCCATACTGGCACGAAACCGCACCAATGTGACGTTTGCGGTAAAGCGTTCCTGTACAAAGCCAACTTGCTGACTCACCAGAGAGTAAACCACGAAAACTTGCAGGTGTTTCCTGCCTTATTCCAGTGCGAGGTTTGCAACCGCAGTTTCCCATACAAAAAGTCTCTCTTGTTACACCTGAACGCTCATTCAGGTGAGATCCAGTTCTTGTGCGATGTGTGCGGCAAGTCGCTGACCAACGCGCGATCTCTGAAACTCCACCGGCGTCTCCACACGGGGGAGAAACCGTGCGTCTGCGGTGTTTGTGGGAAGGCGTTCACCAAGAGTTACACCTTGAAGGTCCACCAGCTCACTCACACGGGACAGAAACCTCACTGTTGTGACGTCTGTAACAAATCTTTCACCCAGCGCTCAACTCTTGTGGTTCACAAGCGCTACCACACGGGGCAGAGACCCTATATGTGCCCCGTCTGTAACAAGGGTTTTGTGGCCAAGACAATGCTGAACTCGCATCAGAGAAACCACGACCCAAGATGCAGTCTTCGGCAGTGA
- Protein Sequence
- MSSKSKRKVRKGKSNRKVPGEMSNTCKLDIHEMFNESASPDLCPPCDTTFNSKREIEAHLRLHANPTEFVCEHCNKVFTANKRLVNHLKTHSKDRPYSCDICNKSYKRRYELTMHKRIHTGLKSFICNICGYATMYKGYLNIHYKRHLNQFRFRCNICKKGFYTNFELQVHNNVHTGTKPHQCDVCGKAFLYKANLLTHQRVNHENLQVFPALFQCEVCNRSFPYKKSLLLHLNAHSGEIQFLCDVCGKSLTNARSLKLHRRLHTGEKPCVCGVCGKAFTKSYTLKVHQLTHTGQKPHCCDVCNKSFTQRSTLVVHKRYHTGQRPYMCPVCNKGFVAKTMLNSHQRNHDPRCSLRQ*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01446827;
- 90% Identity
- iTF_01446827;
- 80% Identity
- -