Tgen050983.1
Basic Information
- Insect
- Timema genevievae
- Gene Symbol
- Znf423
- Assembly
- GCA_902155825.1
- Location
- CABFWO010008713.1:8889-14216[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.022 4.1 10.0 0.3 1 23 9 32 9 32 0.92 2 18 9.1 1.7e+03 1.8 0.4 1 23 39 65 39 66 0.87 3 18 2 3.8e+02 3.8 2.4 1 23 88 110 88 110 0.94 4 18 0.075 14 8.3 5.3 1 23 114 136 114 137 0.95 5 18 0.1 19 7.9 2.0 3 23 212 234 211 235 0.93 6 18 0.0033 0.61 12.6 4.6 2 23 252 273 251 273 0.96 7 18 0.54 1e+02 5.6 0.5 1 23 283 305 283 305 0.94 8 18 3.1 5.8e+02 3.2 0.6 2 23 313 334 312 334 0.95 9 18 4.3 8.1e+02 2.8 0.1 1 13 383 395 383 399 0.87 10 18 2.5e-05 0.0047 19.3 0.1 1 23 431 454 431 454 0.97 11 18 0.17 32 7.2 0.2 1 23 458 480 458 480 0.97 12 18 0.17 31 7.2 1.4 1 23 488 510 488 510 0.96 13 18 0.0029 0.55 12.8 0.2 1 23 518 540 518 540 0.98 14 18 1.2 2.3e+02 4.5 1.7 1 23 547 569 547 569 0.94 15 18 3.6e-06 0.00068 21.9 1.0 1 23 639 661 639 661 0.98 16 18 1.5e-05 0.0028 20.0 0.4 3 23 669 689 668 690 0.94 17 18 4.8e-05 0.009 18.4 0.2 1 23 715 738 715 738 0.95 18 18 2.6 4.8e+02 3.5 2.9 2 20 740 758 739 762 0.73
Sequence Information
- Coding Sequence
- ATGGATATCCACGCGCACCATCTCTACCGCTGTTCCCTGTGCAAGGAGATGTTCGACTCTAAGGTGGCCATACAGGTCCATTTCGCGGTAAAGCACAGCAATGAATGCAAGCTGTACCGCTGCACAGCCTGCCCATTATCCTCAGCAGTGTTCCGCTCGGAGATGGACTTCGGTCTTCACGTCCGGACAATCCACCACCACCCCCCGCCGCCCCTTCCTCTGTCGCCGACCAAACTTCCCGCCTCCGCATCTCAGCAGCAGTTCCGCTGCTTGTTCTGCCGCCTCAGCTTCCCAACTGAGCACGACATGCAGTTCCACTTGACGGTCCACTCCAAGCAGTTCCACTGTCCTTTCTGTCAAGAGGGCTTTCATGTGGAGTTCTTGTTGGACAAACACATGCAGACTCATCATACCACGCAGGTCCTGAGCAGCAGCTCATCGAATGGCGTGGAAAACCCGAGTCAACAGAAATCCCCCAAGAGCAAACCTTCAAGTGGTGGCAACCCTTCAAACTCCATGGTGACTATTGGAAATAACAATTCTTCTCTCAACATTAACAACAACAACTCCTCGAGAGGCTCCAGCTCAGACAATGGAGTCGCTTCCAAGATACCTGAAAGCGCCAAGAACTGCTGCGACATCTGTGATCGGCGTGACTTCGCCAGTGAGTCCGAGCTGACAGCGCACCGGAAGCTGGTCCACCACGTGAAAACCGCCGGCGCTGGTGGGGGTAAGAATGGTGCCGTCAGTCTCCACTGCGCCTACTGCAGCGAGAACTGCAAGTCCAGGACGGAACTGGAGAACCATATGAAGACTCACTCCCAGGGCAGTGGAGGTTCGGGGAAACACAAGTGCAACATCTGCGATGAGCTGTGTCCGTCGGCGGCCATCTTGGCAGAGCACAAGTTGACGCACTGCAAGGTGGTCTCTGGGAGCGTCTGCACGCAGTGCAAGTCCAATCTTGTCAGCGAGGAGCAGTTCTACTCGCACCTGCAGCAGCACGGAGGGGGTGGGGCAAACAACTCTACCAACAGCCCTCAACAGGTTGCCTTACCGACGCCATGCGTCGTCTGCAGACAGACGTTGATATCCGACATTGAGGTCCGCATGCACGCCCGGTTTCACCTGAAGAACTCCGAGCCGACCTACCAGTGCTTCCTGTGCCTGAAACAGTTTGAGTCCCAAAACCTGGTGGTGGCCAACGGAGGCCACCAGGCCGCCACCTACGTGTGCAAGGAGTGCTACCACTGCCACAGTAAGACATCGCCGTCCCCAAGCCAGGAGCAGGCGTTCAGATGTCCAGAGTGCCAGGTCAAGTTCGAGACGAGCTCTGCGCTGGAGGCTCATCTAGTGACCGTCCATAAGAAAACCTACCAGTGCATCAAGTGCCAGATAAGTTTCGAGACTGAACGTGAGATCCAGCTTCACGTGGCTACCCACCTGCTGACTGAGGGCAGCAGCCACGAGTGCCACCTTTGTCGCCGCCTGCTGTCCACACCACTTAAGTTGCAGGCCCACCTCATAGAACACACCTTCGCGGGCTGCGGCAGCTACACCTGCTACCTGTGCAGCGCGGTCTTCACGGCGTCACAAGGCCTGCAGCAGCACATGCTAGAGCATGGCCTGGCGGCCAGGCCTTACGACTGCTCCAGGTGTAGCCTGCGGTTCTTCTTTAGAGCGGAGCTGGACAACCACAGCTACAGCCACCTGGAGGAGGCTATGGTTGGAGGTTCCGGGGCACTAATAGATGGAGGCGACCTGGCTACCAAGGCTGCGTTTTACCATCATCTGACCACAAACGGCTCCTACGACCCCTCGCCCGATCTACAGTACTACAAGACCTTGAGTCAAGACCCGGTCCAGCAGAAACCACACCGACCCAAGGGGGGCAAATCGGGCCCTAAAGGGGGCACGTTCAGGTGCTCGGAATGTGGGAAGGAGTTCAGTAGCGCCCTGGGTCTGCAGGCGCATCAGCGCCATCACAACAAGCACTCCAGGAGGTCGTGTGTGGAGTGCGGCAAGGAGTTCAGCTCCGCCAGGAACCTTGGGGTACACATGAGGGCCCACCACCCCGGAGAGCACAGTTCTGATGACAGGACGACATCTGACGAGAGACTTGATGGCGTGAAGCAGGAGAGAGGCCACCCCTGCACCGTCTGTCAGAAGGAATTCTCGGACGCCGACTCGTTGGAGGTCCACGTCTTGTCCCAGCATTCCCGGTGCCCGCATTGCGGTGAGGCGTTCCTTCACCAGACTCTCTGCGTCCAACATATCGCGCATGCGCATCCAGAGAGCGTCGCCATCAAGCAGGAACCGGCGGTGATAAAACAGGAGGATGAGGAGGATCTCGACGTGGCCTCCTTGTCGGCTCCTACCGTCGTGGAGGAGCACTACGGCCCGGGTCTGGACGAGGTGCCGGTGGATGTTGTGGGGGACGCCTCGCCCTTCGACGAAGACACGCGCAAGGACGACTCGTCGACGAATCAGAGTGAGGTGAACAATTCCGTCACTTCCTGTGAAGACAGTGATGACGTGAACAAGCGACAGTAG
- Protein Sequence
- MDIHAHHLYRCSLCKEMFDSKVAIQVHFAVKHSNECKLYRCTACPLSSAVFRSEMDFGLHVRTIHHHPPPPLPLSPTKLPASASQQQFRCLFCRLSFPTEHDMQFHLTVHSKQFHCPFCQEGFHVEFLLDKHMQTHHTTQVLSSSSSNGVENPSQQKSPKSKPSSGGNPSNSMVTIGNNNSSLNINNNNSSRGSSSDNGVASKIPESAKNCCDICDRRDFASESELTAHRKLVHHVKTAGAGGGKNGAVSLHCAYCSENCKSRTELENHMKTHSQGSGGSGKHKCNICDELCPSAAILAEHKLTHCKVVSGSVCTQCKSNLVSEEQFYSHLQQHGGGGANNSTNSPQQVALPTPCVVCRQTLISDIEVRMHARFHLKNSEPTYQCFLCLKQFESQNLVVANGGHQAATYVCKECYHCHSKTSPSPSQEQAFRCPECQVKFETSSALEAHLVTVHKKTYQCIKCQISFETEREIQLHVATHLLTEGSSHECHLCRRLLSTPLKLQAHLIEHTFAGCGSYTCYLCSAVFTASQGLQQHMLEHGLAARPYDCSRCSLRFFFRAELDNHSYSHLEEAMVGGSGALIDGGDLATKAAFYHHLTTNGSYDPSPDLQYYKTLSQDPVQQKPHRPKGGKSGPKGGTFRCSECGKEFSSALGLQAHQRHHNKHSRRSCVECGKEFSSARNLGVHMRAHHPGEHSSDDRTTSDERLDGVKQERGHPCTVCQKEFSDADSLEVHVLSQHSRCPHCGEAFLHQTLCVQHIAHAHPESVAIKQEPAVIKQEDEEDLDVASLSAPTVVEEHYGPGLDEVPVDVVGDASPFDEDTRKDDSSTNQSEVNNSVTSCEDSDDVNKRQ*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01446962;
- 90% Identity
- -
- 80% Identity
- -