Tgen044620.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Timema genevievae
Gene Symbol
-
Assembly
GCA_902155825.1
Location
CABFWO010005796.1:25071-31101[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 1.4e-05 0.0025 20.1 0.4 2 23 394 415 393 415 0.97
2 10 0.014 2.6 10.6 0.4 1 23 425 447 425 447 0.97
3 10 7e-06 0.0013 21.0 0.6 2 23 509 531 508 531 0.94
4 10 0.052 9.8 8.8 0.9 1 23 616 639 616 639 0.94
5 10 1.2e-05 0.0023 20.3 1.5 2 23 681 702 680 702 0.97
6 10 2.2e-06 0.00042 22.6 0.5 1 23 708 730 708 730 0.98
7 10 6.4e-06 0.0012 21.1 1.7 1 23 736 759 736 759 0.96
8 10 1.4e-07 2.6e-05 26.4 0.7 1 23 765 787 765 787 0.99
9 10 1.1e-05 0.002 20.4 4.4 1 23 793 815 793 815 0.98
10 10 6.8e-07 0.00013 24.2 0.7 1 23 821 843 821 843 0.97

Sequence Information

Coding Sequence
ATGGAAGATTCTGGCGGCTTGCCGTCTGTGTCGGCGCATCGAGACTCCCAGCTAGTCTTAGACTCCATAGTTCCCACTATCCGCTCTGAGGTGGTGAAGCTCTGCAGCGCCGACCCAAGCAAGAGCAAACCAGGTGCGGATGTCGAAGAACCGAGGGCTACCGAGCTCATCAGTACCCAGTACATCAACATCCATCGAGTGTCTGATGATGTCAGCCTGGATAAAGCTCTGGTGGACAATACTGAGCTGATCCAGCACCACGTACTTCACGGAGGAATGGTGGTGGACATGATGGTGCCTGTGTCTGCCGGAACAGCGCCAGACTTCTCCCATGCCACCCATCAGTATATCTCAGACCACTACGACACAGACGCCATCCTGACAGACCATCTCACCGAGGAAGACAAGAAGTTAGCGGCTGCGCTAGTAGCGGTGCAGCTCGTTCACCAACAAAAACAGCACCACGTGGGATCGGATTCCAACACGATCGTGAGCACGGCCGGACTGTCAGGGTTCACGTCTCCTGTGTCCGTGACGCGGCTCTCCAAGATGCACCAGCACATACCGGTGTCTCTAGCCGACCACTCTCAGATAGCCTCACTGGGGGCCATGTCACCGGTGTCTGTGACACAACTCGCCAAGATGCACCAACACATACCGGTGTCTCTAGCCGATCACTCTCAGATAGCCTCATTGGGGGCCATGTCCCCGGTGTCTATCGTGGACAAGCCCACAGTGTCGGCGATGGTTTCTAGTTTCATACAGGCTGTGGAGGAAGAGGTGGCGGTGCAACAGAGCCTGTTGGAGCATCATGGCGCTGACACGCAAACTATGAAGCTGTACCAGCCACAGCTTCCGCTTCCCCCGCTCAAGAAGGTGCTCTCCAGTCATTCTATAGGCACAAGGAGGCCCCAGATAACCCCAAACCAAGTGACCACTCTGTCAGAGCAGCTCAAGGAGGAATATGGCATCAAATGTGAGGGCATGGACGAAGACCTTGGAGATGACAGCGAAGAGAATGGTCGTGACGAAGATGATGACAACGACTCAGACTTTGACCTGGAGACCCATCTGCGGCCGTCGCGGCGCTCCCTCCCTCACAAAAAGCGCATTTCTCGCAAGCTAAAGAACCTCAAGAAGGCCTCATCTCCTTCTCGAAGCATCCTCAACAAGTGTCTCAAGTGTAACAAGTGTGGGGAACAGTTTGTAAATCAAGCAGCATTAACCTCGCACCGACTCACGCACTTGCCTAGCGCTGCCAAGAAGCCTTCCTTCAACTGTGAGCTGTGCGGGAAGGCTATTGCCAATCAGCTCAAGTTCTTTGAGCACCTCAAGTCACATTACGAGCCCGCCTTGTTGAATAATAATGATGAGGTGATCAACGACCTTGACACTGCCCAGACAAGTTCCAAGCAAAACACTTCCAAAGAGTGTGTGCTTCCCCCCGTTAAGTCTGTCGAAGGAGGAGAGATAGAAGTGGGAAAGCCAGCGCCGGAGCTCGTAGGggccctccctcccccccttacTTGCCCTCAGTGCGGCAAAACGTTCCGCCGCCAGAGGACGTTTGAGACACATGTGAGTGTGGCTCACCCGAAGCAGGAGGAGATCGAGGAGTTCAGTGAGCCTGAGGACTTGATGGAGGGTATTAGAGGGGTGGGGGTAGGGGTAGAAGACGACTCAGGTGACGACATGACCTGTCTACCGCCTGTCCGAGGACTCAAGCCAGGAGTGGACAAGGTATGGTACCGAGAGGAGGACCTTCACGCCACAGAGGTTGACCTGCAGGCTATAGAGGCACAGCACCATCAGGTGTCCCACGACGGACTCACCAGTGAGGAGGATCACATTTGTGAACTTTGCGGCGACATCTACGAGAGCCGGCATACTCTGACCCAGCATGTCAGGGCAGAGCACCTGGATCTCCACGACCGCCGCGATGGGATCATCATCCCGCTCAAGAGAAAGGGTGGGGGGCCCTTCTCAATGACAGGCAAGCACTCTAGGAGCTCACACAAGCGAGCTGGCTCCCTCACTCTGACCTGCCCCCAATGTGGGCGAGTGTTTAACCACCGCAACTCGCTGGTATACCACCTGCGCTCGCATTCGGGCGAGCGGCCACACCAGTGTGAGGTGTGTGGCAAGAGCTTCTTTGCTGCGAGTGCACTCAAGGTTCACATGCGTCTTCACTCGGGGGACAAACCCTACAAGTGCGAGAACTGCGGCCGCCACTTCAGGCAGTGGGGGGACCTCAAATACCACCGCATCTCGATACACACGGCTCAGAGGAACTACCAGTGTGAATACTGTGGCAAGGACTTTGCGCGCAAATACTCGCTCATAGTCCACCGGCGTATTCACACCGGTGAGAAAAACTACTGCTGCGAGTACTGTAACAAGAGCTTCCGAGCCTCGTCCTACCTGCAGAACCACCGGCGCATTCATACAGGTGAGAAGCCACATCCGTGTCCAGTGTGCGGCAAACCGTTCAGAGTGCGGTCGGACATGAAGCGCCACCTCAACACGCACCAGCGGGACCGTGGGTCCCGAGGAGGGGGTACTCTGTCCTCCACTAAACTGGAAACTCCGGACGAGATGGAGGATGTAGACCAGGAGGAGCAGGCGGCCATCACAGGACTTGCTCAACATCACACTATGCAGGCTATGTCTCACATGACACCAGTGACGGAGATCACCATCCAATCAGAGCAGACCACGGACAGTATCCTACCCGACGATCACATGGCTGAGAGCGACCAGCAGCCCATCAACCTCAACATTGCCGTGCCTGCCCGTCATGCGTTGGGCCCTGATGAGGTCATCCACTACACTAGGGACCCTCTAGAAACTGTCAGGGACGGGACAGTGTTCGTGTGGCCTATCTACATGGCATAG
Protein Sequence
MEDSGGLPSVSAHRDSQLVLDSIVPTIRSEVVKLCSADPSKSKPGADVEEPRATELISTQYINIHRVSDDVSLDKALVDNTELIQHHVLHGGMVVDMMVPVSAGTAPDFSHATHQYISDHYDTDAILTDHLTEEDKKLAAALVAVQLVHQQKQHHVGSDSNTIVSTAGLSGFTSPVSVTRLSKMHQHIPVSLADHSQIASLGAMSPVSVTQLAKMHQHIPVSLADHSQIASLGAMSPVSIVDKPTVSAMVSSFIQAVEEEVAVQQSLLEHHGADTQTMKLYQPQLPLPPLKKVLSSHSIGTRRPQITPNQVTTLSEQLKEEYGIKCEGMDEDLGDDSEENGRDEDDDNDSDFDLETHLRPSRRSLPHKKRISRKLKNLKKASSPSRSILNKCLKCNKCGEQFVNQAALTSHRLTHLPSAAKKPSFNCELCGKAIANQLKFFEHLKSHYEPALLNNNDEVINDLDTAQTSSKQNTSKECVLPPVKSVEGGEIEVGKPAPELVGALPPPLTCPQCGKTFRRQRTFETHVSVAHPKQEEIEEFSEPEDLMEGIRGVGVGVEDDSGDDMTCLPPVRGLKPGVDKVWYREEDLHATEVDLQAIEAQHHQVSHDGLTSEEDHICELCGDIYESRHTLTQHVRAEHLDLHDRRDGIIIPLKRKGGGPFSMTGKHSRSSHKRAGSLTLTCPQCGRVFNHRNSLVYHLRSHSGERPHQCEVCGKSFFAASALKVHMRLHSGDKPYKCENCGRHFRQWGDLKYHRISIHTAQRNYQCEYCGKDFARKYSLIVHRRIHTGEKNYCCEYCNKSFRASSYLQNHRRIHTGEKPHPCPVCGKPFRVRSDMKRHLNTHQRDRGSRGGGTLSSTKLETPDEMEDVDQEEQAAITGLAQHHTMQAMSHMTPVTEITIQSEQTTDSILPDDHMAESDQQPINLNIAVPARHALGPDEVIHYTRDPLETVRDGTVFVWPIYMA*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01450840;
90% Identity
iTF_01445869;
80% Identity
-