Basic Information

Insect: Timema genevievae
Gene Symbol: -
Assembly: GCA_902155825.1
Location: CABFWO010012224.1:614-2230[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00041 0.077 15.4 0.4 1 23 73 96 73 96 0.97

2 14 0.00028 0.052 16.0 1.1 2 23 121 142 120 143 0.94

3 14 0.00084 0.16 14.5 0.5 3 23 150 170 149 170 0.97

4 14 0.00025 0.047 16.1 4.2 1 23 176 198 176 198 0.98

5 14 1.9e-07 3.5e-05 25.9 0.8 2 23 205 226 204 226 0.97

6 14 8e-06 0.0015 20.8 0.7 3 23 234 254 233 254 0.99

7 14 2e-06 0.00037 22.7 1.4 2 23 261 282 260 282 0.94

8 14 0.00029 0.054 15.9 1.0 1 23 288 310 288 310 0.98

9 14 5.7e-06 0.0011 21.3 2.5 1 23 316 338 316 338 0.98

10 14 0.061 11 8.6 0.6 1 23 353 375 353 375 0.97

11 14 0.0076 1.4 11.5 0.1 1 23 382 404 382 404 0.95

12 14 3.4e-06 0.00063 22.0 0.7 1 23 410 432 410 432 0.96

13 14 6.7e-06 0.0013 21.1 1.1 1 23 438 460 438 460 0.99

14 14 1.6e-07 2.9e-05 26.2 1.4 1 23 466 488 466 488 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00041	0.077	15.4	0.4	1	23	73	96	73	96	0.97
2	14	0.00028	0.052	16.0	1.1	2	23	121	142	120	143	0.94
3	14	0.00084	0.16	14.5	0.5	3	23	150	170	149	170	0.97
4	14	0.00025	0.047	16.1	4.2	1	23	176	198	176	198	0.98
5	14	1.9e-07	3.5e-05	25.9	0.8	2	23	205	226	204	226	0.97
6	14	8e-06	0.0015	20.8	0.7	3	23	234	254	233	254	0.99
7	14	2e-06	0.00037	22.7	1.4	2	23	261	282	260	282	0.94
8	14	0.00029	0.054	15.9	1.0	1	23	288	310	288	310	0.98
9	14	5.7e-06	0.0011	21.3	2.5	1	23	316	338	316	338	0.98
10	14	0.061	11	8.6	0.6	1	23	353	375	353	375	0.97
11	14	0.0076	1.4	11.5	0.1	1	23	382	404	382	404	0.95
12	14	3.4e-06	0.00063	22.0	0.7	1	23	410	432	410	432	0.96
13	14	6.7e-06	0.0013	21.1	1.1	1	23	438	460	438	460	0.99
14	14	1.6e-07	2.9e-05	26.2	1.4	1	23	466	488	466	488	0.98

Sequence Information

Coding Sequence: ATGTTTGAAGGCGAAGAGTTTGAAGTGCTCAGCCGAGAGGAACTTGAGTCAAGAGAGGCAGAGGGTTGCTGTGAAAACGAGGAGAGTTGTGACTATGTACAGGGAGATTTCGGACATCTTGTCAGCGTATCTCTTGGTAGGGAGGCGGAAGCCGAAACAGAACCAGTTCAAGATGGAGTAGTCATTGAGAACATTTCAACAACCGAGGTTAAACAATATAGATGCTTAAACTGCGATCAAACCTTTAATGAAAATAGTAAGTTATTGATTCATGAAATAACCGAACACATTGTTGAAAAACAAACCAAGGCTAATAATGAGTCATTCGTGTCCCACATACGATACAGACGAGAGAAGATGGAGTGCAAGGAATGTGGAAGTGTGTTTAATGGGAGGAAGCCTTTGAAGAAACATATACGAGAGCATCACATCCCAGCAGAGAATATCTGTCCCTTCTGTGGTGctcactataaaataaaaagtcaatTGCTTGTTCATCTCCGTTTACACACAAACGAAAAACCGTTTGTGTGTTCTGTTTGCACTGAAACATTCCACTTCAAAAAAGAGCTTCGGAGGCACAAACGTATTCATCTCGTATCAAAATCATTGACGTGCCATATCTGTGATAAGTCCTTCACCAACAGGGCAGCTTTGTGGCGACATGCCAGAATTCACACCATCAACAGGAACGTACTGTGCTCTCAGTGCGGTAAAATTCTCTCCAACTCACAGAGTCTCAGGGTGCACATGAGGACTCACTCGAGTGACCGCCCCTGCTCCTGTCCCACATGCGGGAAAAGTTTCAAGGACAACGCTTCTCTCACCAGGCACGAAGTGATGCATTCTGCTTTGAGGAATTTCAGGTGTGACATATGCCAACGAGCGTTTTATAGCAAAGCTCTGGTGAAACAGCATAAGTTGAGCCACTCGGGTGTCAAACCTCACAAGTGCAATGTGTGTGGCGCATCTTTCAACAGGCTGGGCAACTTGAACCAGCACAAAAAGAAACATGTTGACTCGGACGGGAAGACCGAGTCCAAGAATGAAATTGCTTATGAGTGTGTAGTCTGTAACAAACGAATGCGATCTGAGCTGACCCTTAAATATCACCTTGCAAAACACACTGGGGAGAAGAAACCATTTGACTGCATGGCTTGCGGCAAACGGTTTACTGCGATAGAGCCATACCGCGTACACATGCGTATCCACACAGGTGAACGCCCATATGTCTGCAACACATGTGATAAGGATTTTCGCAGCGCTTATACACTTAAGCAGCACATGGGACTTCACAAAGATGAGTGTCCATACCCTTGTCCGTTTTGTGAGCGACGGTTCAAGAGGTTGCAGTCGCTCATCGTTCACAAGCGTACACATACGGGAGAGAAGCCCCATCAGTGTCCCGAGTGCGGCCGGCGCTTTGCTCAGAAAGGGGATATGTTGAAGCACATGAAGACTCACTTTCGAGACCAACCTTATTTGGGCAGCCAAGTCCCTGAGGAAATGGTTCTGGAGATAGACAATATTGCAGAGTTTGCGCTCAGTGACACAGACATGACCAACGAGTTTCTCATCGACATGCCGATTGTAGAGGTAGAAACAGAGTTGCACTGA
Protein Sequence: MFEGEEFEVLSREELESREAEGCCENEESCDYVQGDFGHLVSVSLGREAEAETEPVQDGVVIENISTTEVKQYRCLNCDQTFNENSKLLIHEITEHIVEKQTKANNESFVSHIRYRREKMECKECGSVFNGRKPLKKHIREHHIPAENICPFCGAHYKIKSQLLVHLRLHTNEKPFVCSVCTETFHFKKELRRHKRIHLVSKSLTCHICDKSFTNRAALWRHARIHTINRNVLCSQCGKILSNSQSLRVHMRTHSSDRPCSCPTCGKSFKDNASLTRHEVMHSALRNFRCDICQRAFYSKALVKQHKLSHSGVKPHKCNVCGASFNRLGNLNQHKKKHVDSDGKTESKNEIAYECVVCNKRMRSELTLKYHLAKHTGEKKPFDCMACGKRFTAIEPYRVHMRIHTGERPYVCNTCDKDFRSAYTLKQHMGLHKDECPYPCPFCERRFKRLQSLIVHKRTHTGEKPHQCPECGRRFAQKGDMLKHMKTHFRDQPYLGSQVPEEMVLEIDNIAEFALSDTDMTNEFLIDMPIVEVETELH*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01444997;
90% Identity: iTF_01444997;
80% Identity: -