Basic Information

Insect: Timema genevievae
Gene Symbol: zfh1
Assembly: GCA_902155825.1
Location: CABFWO010003210.1:65238-71849[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 2.5e-06 0.00046 22.4 0.7 1 23 6 28 6 28 0.99

2 20 7e-08 1.3e-05 27.3 1.3 1 23 34 56 34 56 0.99

3 20 9.2e-06 0.0017 20.6 0.8 1 23 62 84 62 84 0.98

4 20 0.59 1.1e+02 5.5 0.4 1 14 90 103 90 104 0.92

5 20 0.0036 0.68 12.5 0.2 2 23 138 160 137 160 0.95

6 20 0.037 6.9 9.3 2.2 1 21 165 185 165 187 0.93

7 20 0.0045 0.85 12.2 0.4 1 23 193 215 193 215 0.98

8 20 0.01 1.9 11.1 0.3 1 23 221 243 221 243 0.95

9 20 1.7e-07 3.2e-05 26.1 1.7 1 23 249 271 249 271 0.98

10 20 0.046 8.6 9.0 1.6 1 23 281 303 281 303 0.94

11 20 2.2e-06 0.00041 22.6 0.1 1 23 309 331 309 331 0.98

12 20 3.3e-08 6.2e-06 28.3 1.3 1 23 337 359 337 359 0.99

13 20 2.8e-05 0.0053 19.1 3.0 1 23 365 387 365 387 0.99

14 20 1.1 2.1e+02 4.6 0.2 1 13 393 405 393 406 0.90

15 20 0.0019 0.36 13.3 0.9 2 23 456 477 455 477 0.95

16 20 0.0036 0.68 12.5 0.2 1 20 481 500 481 502 0.94

17 20 3.8 7.2e+02 2.9 0.1 12 23 508 519 504 519 0.88

18 20 8.4e-08 1.6e-05 27.0 1.4 1 23 525 547 525 547 0.98

19 20 2.2e-06 0.00041 22.6 1.4 1 23 553 575 553 575 0.99

20 20 0.00076 0.14 14.6 5.0 1 23 581 603 581 603 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	2.5e-06	0.00046	22.4	0.7	1	23	6	28	6	28	0.99
2	20	7e-08	1.3e-05	27.3	1.3	1	23	34	56	34	56	0.99
3	20	9.2e-06	0.0017	20.6	0.8	1	23	62	84	62	84	0.98
4	20	0.59	1.1e+02	5.5	0.4	1	14	90	103	90	104	0.92
5	20	0.0036	0.68	12.5	0.2	2	23	138	160	137	160	0.95
6	20	0.037	6.9	9.3	2.2	1	21	165	185	165	187	0.93
7	20	0.0045	0.85	12.2	0.4	1	23	193	215	193	215	0.98
8	20	0.01	1.9	11.1	0.3	1	23	221	243	221	243	0.95
9	20	1.7e-07	3.2e-05	26.1	1.7	1	23	249	271	249	271	0.98
10	20	0.046	8.6	9.0	1.6	1	23	281	303	281	303	0.94
11	20	2.2e-06	0.00041	22.6	0.1	1	23	309	331	309	331	0.98
12	20	3.3e-08	6.2e-06	28.3	1.3	1	23	337	359	337	359	0.99
13	20	2.8e-05	0.0053	19.1	3.0	1	23	365	387	365	387	0.99
14	20	1.1	2.1e+02	4.6	0.2	1	13	393	405	393	406	0.90
15	20	0.0019	0.36	13.3	0.9	2	23	456	477	455	477	0.95
16	20	0.0036	0.68	12.5	0.2	1	20	481	500	481	502	0.94
17	20	3.8	7.2e+02	2.9	0.1	12	23	508	519	504	519	0.88
18	20	8.4e-08	1.6e-05	27.0	1.4	1	23	525	547	525	547	0.98
19	20	2.2e-06	0.00041	22.6	1.4	1	23	553	575	553	575	0.99
20	20	0.00076	0.14	14.6	5.0	1	23	581	603	581	603	0.99

Sequence Information

Coding Sequence: ATGGGCGAAAACAAGTTTCAGTGCGACCTGTGCGGAAAGACGCTCAACTCTAAGGCATACCTAAGGACGCACTTACGCATACACAGTGGCGAGAAGCCTTACGTTTGTGACGTGTGTGGCAAGGCTTTCGTGACAAACAAACACTTGACTATCCACCGGCGCACGCACACCGGCGAGAAGTTATATGTGTGTAATGTGTGTAACAAGTCTTACACGCAGGTGGGTTATTTGACCATCCACAAGCGCTCACATACGGGCGAGCGACCGTACCACTGTGATGCCTGCGGAAAGGACTTTGCTTCCAAGTCTCCAAGACCGGCTCCAAGACCTGCTCCACGACCGGCTCCAAGACTGAATCAAGTCATCACTCTTCTCAAGCCCAAGCAACCAGAACCTAAAAGGGACCTCTGGAAGTGCACGCCGTGCGGCCAAAGCTTTGCCCTCCTCTCCGAGTTTAAAAGCCACATAATGTCACAGCACCGACGAAACTCGCACCCGTGCGACATGTGTGACCTCAAGTTCATATCCCCGGTACGACTCGCCAAACATAGGAAATGTCATGGGGTGATGATAAGATACTCGTGCGATATATGCGGCTACTCCGGGCAGAGCAAGACGTTGGTAGAAACGCACCGAAAGATGCATTACAACGAGTACAAGTATTACTGCAGTATCTGTTCTCGAGGTTTTAACGTGGTGAAACTCCTGAAGGAACACGAGCTGCTGCATACCGGAATCAAACCGTACCAGTGTGAGGAGTGCGGTAGACAGTTCACCTCAAAGTACAATCTCGCCAAGCACAAGCGTCTTCATGAGCCGGGCTACAAAGACAACCCAAAGTTCTTTTGCGAGTTTTGCGGCCGGTCGTTCTTGTACAGCACGGTCTTGAACAAGCACCGCAGTGGTCACCTGGGTGAGAACCGGTTCGAGTGCGACGTTTGCGGTAAGGTCGTCAACTCCAAGGAGTACCTAAAGGTCCACCTTCGGATCCACAATGGTGACAAACCGTACGTGTGTGACATCTGTGGCAAGGCGTTTGTGACCAACAAGCACCTGACCGTTCACAGACGCACGCATACGGGGGAGAAACTTTACACGTGTAATGTATGTCACAAGTCGTACACACAGGTGGGGTACCTCACCATCCACAAGCGCTCACACACGGGAGAGCGCCCGTATCATTGTGTTGTTTGCGGTAGGGACTTTGCCTCCAAGTTGGTAAACTTGATTACGGGTAGCGCGCAGGCCCACCCAGCCTTGATGCCAAACGTAGCTTCAGTTGTAAAACAGAACATTGTCCGCGATAAGACCCCCGAGAAGGTTTCGGTGAAACAGTCTTTAGTCGACAGCGGCAGGATTCAGTGGAGGTGCAAGGTCTGCAATAAGATCTTCCGACAGGATTGGCAGTACAAACTTCATCGCGTGTCTCATGTGAAAGAGTACACTTGCAACATCTGTAAGACAAAGTTTGCAAGCGAAGAAGCGCTCTCTCTCCACAAGACGAGTGATGTGCCGCTCGCGTCGAAAAAATACATGACGGTCCACATGCGAATACACAGCGGAGAAAAACCGTTTGTTTGTGATGTTTGTGGCAAGGCGTTTGTCACTAACAAGCATTTAACGGTTCACCGACGCACACATACGGGGGAGAAACTTTACACGTGTAACGTGTGTAACAAGTCATTCACGCAAGTGGGTTATTTGACAATTCACAAGCGCTCTCATACTGGCGAGCGCCCATATCGGTGTGAGACGTGCCGTAAAGACTTTGCTTCCAGGTGTCAACTCAACTCTCATCGTAAATCACATAGATAA
Protein Sequence: MGENKFQCDLCGKTLNSKAYLRTHLRIHSGEKPYVCDVCGKAFVTNKHLTIHRRTHTGEKLYVCNVCNKSYTQVGYLTIHKRSHTGERPYHCDACGKDFASKSPRPAPRPAPRPAPRLNQVITLLKPKQPEPKRDLWKCTPCGQSFALLSEFKSHIMSQHRRNSHPCDMCDLKFISPVRLAKHRKCHGVMIRYSCDICGYSGQSKTLVETHRKMHYNEYKYYCSICSRGFNVVKLLKEHELLHTGIKPYQCEECGRQFTSKYNLAKHKRLHEPGYKDNPKFFCEFCGRSFLYSTVLNKHRSGHLGENRFECDVCGKVVNSKEYLKVHLRIHNGDKPYVCDICGKAFVTNKHLTVHRRTHTGEKLYTCNVCHKSYTQVGYLTIHKRSHTGERPYHCVVCGRDFASKLVNLITGSAQAHPALMPNVASVVKQNIVRDKTPEKVSVKQSLVDSGRIQWRCKVCNKIFRQDWQYKLHRVSHVKEYTCNICKTKFASEEALSLHKTSDVPLASKKYMTVHMRIHSGEKPFVCDVCGKAFVTNKHLTVHRRTHTGEKLYTCNVCNKSFTQVGYLTIHKRSHTGERPYRCETCRKDFASRCQLNSHRKSHR*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01445854;
90% Identity: iTF_01445854;
80% Identity: -