Tgen033469.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Timema genevievae
Gene Symbol
Znf296
Assembly
GCA_902155825.1
Location
CABFWO010003210.1:4303-22616[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 52 0.00014 0.026 16.9 0.9 2 23 46 68 45 68 0.94
2 52 0.0018 0.33 13.4 7.5 3 23 72 92 71 92 0.98
3 52 0.086 16 8.1 0.6 2 23 99 120 98 120 0.96
4 52 0.16 29 7.3 0.3 1 23 126 148 126 148 0.96
5 52 2.1e-06 0.00039 22.7 3.1 1 23 154 176 154 176 0.99
6 52 8.1e-06 0.0015 20.8 0.3 1 23 181 203 181 203 0.99
7 52 0.0002 0.037 16.4 4.4 1 23 209 231 209 231 0.97
8 52 1.8e-05 0.0034 19.7 4.2 1 23 237 259 237 259 0.96
9 52 2.7e-05 0.0051 19.1 6.4 1 23 265 287 265 287 0.97
10 52 0.12 23 7.7 5.0 1 23 360 383 360 383 0.93
11 52 0.0089 1.7 11.2 2.7 1 23 387 409 387 409 0.93
12 52 1.8 3.3e+02 4.0 0.8 2 23 416 437 416 437 0.95
13 52 0.007 1.3 11.6 0.3 1 23 443 465 443 465 0.95
14 52 0.00044 0.082 15.3 4.7 1 23 471 493 471 493 0.99
15 52 0.0067 1.3 11.6 1.4 1 23 504 526 504 526 0.98
16 52 0.00065 0.12 14.8 1.2 1 23 533 555 533 555 0.97
17 52 3.2e-06 0.0006 22.1 0.3 2 23 562 583 562 583 0.97
18 52 2.1e-07 3.9e-05 25.8 1.5 1 23 589 611 589 611 0.98
19 52 3.6e-05 0.0067 18.8 2.6 1 23 617 639 617 639 0.99
20 52 0.049 9.2 8.9 3.2 2 23 687 707 686 707 0.88
21 52 0.0001 0.019 17.4 0.0 1 23 713 735 713 735 0.97
22 52 0.00018 0.034 16.6 3.0 1 23 741 763 741 763 0.97
23 52 0.00023 0.043 16.2 3.5 1 23 769 791 769 791 0.97
24 52 0.00035 0.066 15.6 0.5 2 23 798 819 797 819 0.95
25 52 0.0017 0.32 13.5 2.7 1 23 825 847 825 847 0.98
26 52 1.5e-05 0.0028 19.9 1.6 1 23 858 880 858 880 0.99
27 52 2.3e-05 0.0043 19.4 0.5 2 23 887 908 886 908 0.96
28 52 1e-05 0.002 20.5 0.5 2 23 915 936 915 936 0.97
29 52 0.00019 0.036 16.5 3.5 1 23 1019 1041 1019 1041 0.98
30 52 7.9e-05 0.015 17.7 3.4 1 23 1047 1069 1047 1069 0.97
31 52 0.005 0.94 12.0 3.5 1 23 1076 1099 1076 1099 0.94
32 52 0.0036 0.67 12.5 3.3 1 21 1105 1125 1105 1129 0.90
33 52 7.3e-06 0.0014 20.9 1.5 2 23 1136 1157 1135 1157 0.96
34 52 4.7e-07 8.8e-05 24.7 0.3 2 23 1164 1185 1163 1185 0.97
35 52 2.2e-05 0.004 19.5 2.3 1 23 1268 1290 1268 1290 0.97
36 52 0.00032 0.059 15.8 3.1 1 23 1296 1318 1296 1318 0.97
37 52 0.0019 0.36 13.3 1.6 1 23 1324 1346 1324 1346 0.98
38 52 0.023 4.3 9.9 5.1 1 23 1352 1374 1352 1374 0.96
39 52 0.0062 1.2 11.7 0.4 1 23 1380 1402 1380 1402 0.95
40 52 0.0019 0.35 13.4 6.1 1 23 1411 1434 1411 1434 0.98
41 52 0.00013 0.024 17.0 0.9 2 23 1443 1464 1442 1464 0.96
42 52 5e-07 9.4e-05 24.6 0.4 2 23 1471 1492 1470 1492 0.97
43 52 4.3e-07 8e-05 24.8 1.9 1 23 1498 1521 1498 1521 0.97
44 52 0.0082 1.5 11.3 3.3 2 23 1593 1614 1592 1614 0.97
45 52 4.5e-05 0.0085 18.4 2.2 1 23 1620 1642 1620 1642 0.98
46 52 7.3e-05 0.014 17.8 2.2 1 23 1648 1670 1648 1670 0.98
47 52 1.8e-05 0.0034 19.7 0.9 1 23 1676 1698 1676 1698 0.98
48 52 0.0034 0.64 12.5 0.4 1 23 1704 1726 1704 1726 0.95
49 52 0.001 0.19 14.2 3.9 1 23 1736 1758 1736 1758 0.98
50 52 2.4e-05 0.0046 19.3 0.2 1 23 1766 1788 1766 1788 0.98
51 52 7.7e-05 0.014 17.7 1.4 2 23 1795 1816 1794 1816 0.97
52 52 1.1e-05 0.002 20.4 2.2 1 23 1822 1844 1822 1844 0.98

Sequence Information

Coding Sequence
ATGAAGCAGAACTCTAAATCTGCTAAGGTGCCCAAAGGGGACATTAAATCTCTTTCTGGAAGTTTAGCAGTACAGTTTGGACATTGCAACAAGAATGAGAAACAGTCGTCACCTGGTGGTGGTGGTAAAATACTGACGTGTTCCATGTGCAAAGAAAGGTTCACACGCCCAAGACAGCTGCAGCTGCACATGGGAAAGATGCATAAAAACGCATGCGAAGTGTGTCACAAAGTGTTTAGTCGGAAACATCAGCTCCACTACCATAGGAAGTCACATTTTAAAGACAAGAGTTTGATTTGTGACATTTGTGGATACGCGACTTATCTAAAGCGTTTCTTTGAGTCTCATAGGAGAAGACATTTTGGTGATTACACATTCAAATGTGACCAGTGTACCTCTGGGTTCTTCTCGAATGCAGAGCTTTTAGAACACAAGGTGGTCCACACCGGCATGCGGCCATACCAGTGCGAGTTGTGCGGCAAGACCTTCAGTAAGCGTCGTTATCTCTCGACCCACATGCGTTACCATGATAGTAACATATACGTGTGCGACATTTGCGGAAAGTCCATCACTCAGAAGAACTATCTAATAATCCACCTACGAAGACACATGGGAGACAAACGGCACATCTGCGACTTCTGCGGAAAGGCGTTCTGCTCGTCAAACTACCTCAGACTCCACCGCCGCGTTCATACGGGGGAGAAACCCCACAACTGCTCTCACTGTGGCAAGGGCTTCGCTCAGCGCTCGGCACTCAACGTTCACATCAGGCACCACACAGGAGAGAAACCCCACAGGTGTGATACCTGCGGCAAGTGTTTCTCACAGCGCTCGGCGCTCAATGTCCACGTCAGGCATCACACCGGAGAGAAGCCCTTTGTTTGTGCTCTGTGCAGCCAGAGAGCCTTTCTAGACGATTATACATGCCTCGGTAGAAATAATAGCACCACAAAGGAAGAGAGACTAAAAGGGTCAGTAAAAGTGATAAATCTTGCCTCCGAATCAAACTTTGGCAAGAAGATTCCTTCAAAGCGAGTTGCCTCGGAAACTGTCAAGTCTCGGAAGCAGGAAAGAACGTTCTCGTGCACGGGCTGCAGTAAGAAGTTTGTACGGGAACACAAATTGCGCTGCCACATGGACAATGTGCACAACAAGGTTCACAAGTGTACGGTTTGCGGGCAGACGTTCGAGAAAGCGCACCAACTGAGCTATCACAGTGTGGTGcacaaaaaatctaaaacagaAGTATGTGACATTTGTGGTTATACTGCGTATTACAGGTGTGTGATAGAGAATCATAAGAGGACACATTTCTGGGGGAATGAGTTCAGTTGCGACTTGTGCCAGAGAAGCTTTCAGGGTGCATATGCCCTTATGAAACATAAAGTGGTTCACACCGATGTGAAGCAATACCAGTGCGACTTGTGCGGCCGACTATACGTTCACAAGTGTAATCTGACCGCGCATAGGAAGACCCACATCTCGGGATACAAACGCCCCACGGATGGTCACCAGTGCGAGGTCTGCGGGAGAAAGTTCTTGGCGAAGAACTCGCTGGTGAAGCACGTGAGGTCTCATGTCGGCCAGAAACGTTGGTACAAGTGCGACGTATGTGGCAAGGACCTGTCGACGCGAGAGTCACTCCAGGTCCACTGCAGAATCCACACCGGCGAGAAGCCGGAGGTTTGCAACTACTGCGGGAAGACGTTCAGTTCCCGCGTGGGGTTGAAGCTTCACGTTCGCGTTCATACCGGGGAGAAACCGTTCACTTGCAAGGAGTGCGGGAAGAGCTTCACTCAACAGTCGACACTTATCGTCCACAAGAGACTCCATACAGGACAGCGTCCATACGAGTGTCTGAAATGTGATAAGAGGTTCATAACCAAGACAATGATGAACAATCACATGAAGCGTCACGTATGTGCAGATTTAATCCAAACTGATTCTGCAAATAAGTTGAAACGCAAGTCAGCTTACAACAGTAAAGAGAAAAGAGTGAACAATATAGAAAAAAGAATCAGAAATGAAAAAAGACTGAGGAGTGATAGTAGTTCCAACAAATGCGACTTTTGTGGTAAAGAGTTCACCCGGCATAAGATGTTGATTCACCGCAGGATCCATACCGGCGAGCGTCCGTTTGTCTGCTCATCGTGCGGGGAGGCGTTTGTGTCGAAAGGCGCTCTGACTGTTCACATGGTGATACACAGTGATGAGCGTCCCTTTTCCTGCAAGATCTGCCACCGAGCTTTCAAGCGGGCGTTTGAGTTGAAAGACCACAACAAGATACACACTGGGGAGAAGAACCACATCTGCGACATCTGCGGTTATTCGTGCATTCAGAGGACTAACCTCGTAAACCACCGCAGGAGACATTTGTTTGAGTACAAGCTGAGTTGTGACATATGCAGCAAAGGGTTCTACACAAAGACGGAACTGCAGGAGCATAGGAACGGGCATACAGGCGAAAAACCGTTTCAATGCGACACGTGCGGTGTCTCCTATCGCTATCGGTACCGGCTGACTGTCCACAAGAAGAAACACGAGGCGGGCTACATTCCTCCAGAGAAGGCATACAAGTGTGAGATATGTAACAAGACGTATTCTCGTAAGCAAGTGCTGCTACTGCACATGAAGTCGCACACCGGGGAAAGTCAGTGCATATGCGATATCTGCGGCAAGGCGGTTTCGAGCCGGGACTACCTTAAGATACACGTTCGGACGCACACTGGCGAGAAACCAAATGTTTGCGATGTCTGTGGTAAAGCGTTcatttcaaaaaagtatctcaaGATCCATTTCCGCACTCACACGGGTGAGCGCCCGTACACTTGTGAGTTCTGCAGTAAGAAGTGTCGGAAAGAAATAGTTGTAAATAATATCGACTCCTCCAACGCCAGCATTGTTCTTCCTAAAGAGATAAGCAATAAGACAGTCTCATGTTCTAGTAAAGCTAAGTCTGTGAAAACATTGAAGATTGTTGTAAAGAAAGGACAGTTAATGTATAAAAGGGGAAGAGGCAACTGTGCGATAAAACTATCTTCTTGCGAGGACGTTCACAAATGTAACACATGTGGACGAGGGTTTAAACGTAAAACCACGTTAGACTATCACATCATGTCTCACAGCGACGACCGCAATTTCGACTGTTCCATTTGTAAGAAGAAGTTCAAGAGAGACAAGGACTTGAGGAAGCACTTGACGACTCACAACAGGGAACACATGAGGTATTTCTGCAACTCTTGCGACTACGTGTGCAACCGCAAATCCAACTTGGAGCTCCACCGCGTTCGAAGACACTCGAAGGAGTTCAGTTTTTTCTGCGACATTTGCGGCAAAGGTTTCTGTTCCGACTCTCAGCTGCGATACCACCGTAGTAACAAGTCTCACACAGGCGAGAGTCAGTGCGTATGCTCGGTGTGCGGCAAGACAGTCTCTAACAAGTACAATCTCAAAGTGCACGTTCAGACACACACACCAGATAAGCAGATCGTGTGCGATGTTTGTGGTAAGACGTTCACACAGATGAGCAATCTCAAGATCCACTATCGCATTCATACAGGTGAGCGCCCATACTCGTGTGAGTCTTCAACTGTAGAAAATACTCTACTACCCCAGTTGCCAAAAGAAGAAGATATGTCGATACAGCAGTTgtcagaagaagaagaagaagaaaatattattttaccacacATGCTCGAGGATGATAGTGATATGTACCGTGTCGATATGGAGCAAGAGTCAATTTTCACTTCCATTGCTAGTCCTAAAGAAAAGAGTGCAACGTCTCACAAACCCGTGATTCATAAATGCAAAATTTGCGGTAGAGAGTTCAACAGGAAAAACGGTCTAACGAGACACAAGGCAGTTCACAGCGCTATTCGTCCTTACGAGTGCCCTACCTGTGACAAACGGTTCAAGAGAAAATGTGAACTGGACCTCCACAAAGTAACACACACCGATGCTAAACAGTATGCCTGTGATATATGCAGCCTGGTGTGTAATCGAAAAGGTAATCTAGACTCGCACCGCAAGAGACATTTCAATGCCTTTACACATTTCTGTAGCGTGTGCACCAAGGGGTTCTACGACAGTTTCACCATGAAAAGCCACAAGAGGACACACAACAAACTGAAACCTTTCCTTTGTGATCTATGCGGCTGGAAATTCACGACCGGCGCTCAGATGGCGAAACACAAGCTCAAACACGCCCCCGGCTACAAGTCCGAGCTGTTCAGGTGCGACGACTGTGATAAATGTTGCCTGACAAAGTCGAATTTGATGTCGCACGTCAGACGGAGACACGCCGCCGAGGTGGTACCTCAGTGTATTTGCGACATTTGCGGTAAATCGTTATCCTCGAAGGAGTACCTCGTACTTCACAGACGCATACATACGGGAGAAAAACCACTGTCCTGCGATGTGTGCGGGAAGGCGTTCACTCAAGCCAAGTATCTTAAAGTTCACCAGCGCACTCACACAGGGGAGAGGCCATTTTCTTGTAACATCTGTGAGAAACGTTTTACCCAGCGAAGCAGTTTAAATGCACACATGAAATCATACCACAAGTACACTAAACTGCTTAACATAAATTACTGTGCCTTCCACGACGACTGTTTTGTTCCTTCCAAAGAGATAACACCAAAAACAGCCAAGTCTTCCATTGATCATATAAGTTTGACTCGTGTCAAAGAAGAGACCATTGACAAACTCACCGCAGATTCAACGTTAAAGTGTGAAACTTATCCGCTGGACCTGTCGCCTCAAATTCCCACAAATAAATGTGACATTTGTAACAAAACATATCACAAGAAATCCGATCTTGACTatcataaaataacacacagtGATGTTCGGCCATTCGAGTGCTCCGTTTGTAACAAAAGATTCAAGAGAAAATATGAAGTGACTGTTCACAAGTTAACACACACTGGTGACCTGAAATATTCCTGCGATATCTGTAACTTTGTGTGTAACCGTAAAGGGAATCTTGAGGCTCATCGTAAGAGACACATGAATGAGTTTGACTATTTCTGTGATATATGCGGTAAAGGATTCTACAACAATTTCAACTTGCAAGGACACAAAAGAGTGCATATCGGGTTGAAACCTTTCCTCTGTGATCTGTGCGGTTTGGGATTTTCCTACAAAGCAGCCATGAAAAAACATAAACTTAGTCACAATCCCGGATACAAGCCCAAACCAAAACACGAGTGCGACATTTGCGGCAAATGCTTCCTGTCAAAGTCGAGGCTATCGGTGCACATTAAGCGGCATTATGGGGAGGCGTCACCCGGGTTTATTTGCGACTTTTGTGGCAAAGCGGTGTCGTCGAAAGACTCGTTGGTGACCCATCAGCGCATACATACTGGGGAGAAGCCCCTGTCTTGTGATATTTGCGGGAAGGCGTTCAGCCATGTTAAGTATGTTAAAGTTCATCGGAGAACTCATACGGGGGAGCGGCCATATTCTTGTGATGTTTGCCAGAAAACTTTCACCCAACGAAATAGCCTTACTGCACATAAGAAGTCTCacaaataa
Protein Sequence
MKQNSKSAKVPKGDIKSLSGSLAVQFGHCNKNEKQSSPGGGGKILTCSMCKERFTRPRQLQLHMGKMHKNACEVCHKVFSRKHQLHYHRKSHFKDKSLICDICGYATYLKRFFESHRRRHFGDYTFKCDQCTSGFFSNAELLEHKVVHTGMRPYQCELCGKTFSKRRYLSTHMRYHDSNIYVCDICGKSITQKNYLIIHLRRHMGDKRHICDFCGKAFCSSNYLRLHRRVHTGEKPHNCSHCGKGFAQRSALNVHIRHHTGEKPHRCDTCGKCFSQRSALNVHVRHHTGEKPFVCALCSQRAFLDDYTCLGRNNSTTKEERLKGSVKVINLASESNFGKKIPSKRVASETVKSRKQERTFSCTGCSKKFVREHKLRCHMDNVHNKVHKCTVCGQTFEKAHQLSYHSVVHKKSKTEVCDICGYTAYYRCVIENHKRTHFWGNEFSCDLCQRSFQGAYALMKHKVVHTDVKQYQCDLCGRLYVHKCNLTAHRKTHISGYKRPTDGHQCEVCGRKFLAKNSLVKHVRSHVGQKRWYKCDVCGKDLSTRESLQVHCRIHTGEKPEVCNYCGKTFSSRVGLKLHVRVHTGEKPFTCKECGKSFTQQSTLIVHKRLHTGQRPYECLKCDKRFITKTMMNNHMKRHVCADLIQTDSANKLKRKSAYNSKEKRVNNIEKRIRNEKRLRSDSSSNKCDFCGKEFTRHKMLIHRRIHTGERPFVCSSCGEAFVSKGALTVHMVIHSDERPFSCKICHRAFKRAFELKDHNKIHTGEKNHICDICGYSCIQRTNLVNHRRRHLFEYKLSCDICSKGFYTKTELQEHRNGHTGEKPFQCDTCGVSYRYRYRLTVHKKKHEAGYIPPEKAYKCEICNKTYSRKQVLLLHMKSHTGESQCICDICGKAVSSRDYLKIHVRTHTGEKPNVCDVCGKAFISKKYLKIHFRTHTGERPYTCEFCSKKCRKEIVVNNIDSSNASIVLPKEISNKTVSCSSKAKSVKTLKIVVKKGQLMYKRGRGNCAIKLSSCEDVHKCNTCGRGFKRKTTLDYHIMSHSDDRNFDCSICKKKFKRDKDLRKHLTTHNREHMRYFCNSCDYVCNRKSNLELHRVRRHSKEFSFFCDICGKGFCSDSQLRYHRSNKSHTGESQCVCSVCGKTVSNKYNLKVHVQTHTPDKQIVCDVCGKTFTQMSNLKIHYRIHTGERPYSCESSTVENTLLPQLPKEEDMSIQQLSEEEEEENIILPHMLEDDSDMYRVDMEQESIFTSIASPKEKSATSHKPVIHKCKICGREFNRKNGLTRHKAVHSAIRPYECPTCDKRFKRKCELDLHKVTHTDAKQYACDICSLVCNRKGNLDSHRKRHFNAFTHFCSVCTKGFYDSFTMKSHKRTHNKLKPFLCDLCGWKFTTGAQMAKHKLKHAPGYKSELFRCDDCDKCCLTKSNLMSHVRRRHAAEVVPQCICDICGKSLSSKEYLVLHRRIHTGEKPLSCDVCGKAFTQAKYLKVHQRTHTGERPFSCNICEKRFTQRSSLNAHMKSYHKYTKLLNINYCAFHDDCFVPSKEITPKTAKSSIDHISLTRVKEETIDKLTADSTLKCETYPLDLSPQIPTNKCDICNKTYHKKSDLDYHKITHSDVRPFECSVCNKRFKRKYEVTVHKLTHTGDLKYSCDICNFVCNRKGNLEAHRKRHMNEFDYFCDICGKGFYNNFNLQGHKRVHIGLKPFLCDLCGLGFSYKAAMKKHKLSHNPGYKPKPKHECDICGKCFLSKSRLSVHIKRHYGEASPGFICDFCGKAVSSKDSLVTHQRIHTGEKPLSCDICGKAFSHVKYVKVHRRTHTGERPYSCDVCQKTFTQRNSLTAHKKSHK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-