Basic Information

Insect: Timema douglasi
Gene Symbol: -
Assembly: GCA_901482245.1
Location: CABEEJ010003557.1:48554-53459[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 7.5e-05 0.018 17.7 0.2 1 23 448 470 448 470 0.98

2 8 4.6e-05 0.011 18.4 4.3 1 23 476 498 476 498 0.99

3 8 8.5e-06 0.002 20.7 1.2 1 23 504 526 504 526 0.99

4 8 2.6e-06 0.00061 22.3 1.2 1 23 536 558 536 558 0.99

5 8 3e-06 0.0007 22.2 2.8 1 23 564 586 564 586 0.98

6 8 0.0001 0.025 17.3 7.8 1 23 592 614 592 614 0.97

7 8 0.0013 0.32 13.8 1.7 1 23 620 642 620 642 0.98

8 8 0.00011 0.026 17.2 1.0 1 23 648 670 648 670 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	7.5e-05	0.018	17.7	0.2	1	23	448	470	448	470	0.98
2	8	4.6e-05	0.011	18.4	4.3	1	23	476	498	476	498	0.99
3	8	8.5e-06	0.002	20.7	1.2	1	23	504	526	504	526	0.99
4	8	2.6e-06	0.00061	22.3	1.2	1	23	536	558	536	558	0.99
5	8	3e-06	0.0007	22.2	2.8	1	23	564	586	564	586	0.98
6	8	0.0001	0.025	17.3	7.8	1	23	592	614	592	614	0.97
7	8	0.0013	0.32	13.8	1.7	1	23	620	642	620	642	0.98
8	8	0.00011	0.026	17.2	1.0	1	23	648	670	648	670	0.97

Sequence Information

Coding Sequence: ATGGAATGTTGTGATGGGGTTGAAATAATAAACGAAGACGAAGATTCAAACGTGGACAAAGTGACTCAAATGCTTCCAGAGTATTTCGTAAGTGTCAAACTAGAGAACAACGAGGTCGAAGGTTGCTATGACAAAATCAACTGCGCTACTTTGTCGTCTGGTAACTCCAGTGTAGATGTATCGCCGCACGAGAGTTTGTCGCAAACTGAGTTATTCAACATGTCGGAAAGAGTCGCTTCGTCGACGACGGCAGCCATGCAGAGCAACAACAGCCAGAATCACTCGGTACACTCCAACCATACCCCCCACTGTTTCCACCCATCACGGGGACCCAGCATCTCGGACTTACCACCGTGGTTACCCCACTGCTATGCGGGACAATTGACATCGGACTGCACGCAAACCTCCCAACATTTCTTGCCTCAAGCAGCATATTTGGGGCATGATGCATCACAGACTGTCCCCAGAGATCAGAGTTTTGTGTCGGGGCTACCTGCGAGCTATCAGAATAGTGAATTGGGTGCGGCAATTGTGCTAGGTTTGagGTTATCAAAATCTGCAGGGAGCAGGGCAGAGAACCCAGGACCTTCCAGCGGCATTGGTAGTCTAGCGAACGGAGACATATGCGACTCCAACATGTTTCTTAACTACGTCTTAAACCAACAGCGTTCGAGCGGTCTTTTCCTCTTCGATGCCGCAGCACGGTCGCTACATTCTAGCGACACTCTTCACCACGACTCGCCGGGCTGCGAGGGTAGTTCCGATGTCGGAGGAGCCGAAAGCGTGAACAAGTCATTGAACGACTCTTTGGGTAGCGCCAGAGCTAGCAGCCATCCACCAATGAACAGCACCAAGGTGGCGAATCTCGCCGACGATAAAAACTCTCCCACGCACCGTGACGTGGCGACCAACACCGTGTGCAAGTTCACTCCCGCCCCTCAGCATGATCAGACGGGGAACCGCGGGGGCGAACCGGCCGGTGCCTCTTCGTGTTCAGAAACAAATGCCCATCATTGTAAGTGTACCCATAAGTGTCCTGAACGGTCAAGCCACGAACAAGAgaatataaaaagtgaaaacgCGAGGAACTTTTGTTGTAAGTGTCAAGATGGTACTACCGCTAAGCCCGTGTCTATTAGTTTAGGGAATTGTGGGAAATCTGCGGTTTATCACCCTCAAGAGGAGAGTGATCATGACCAAGCATTGTGTCACAGTGTCTTTTGTACGCAATGCTCGTTGAGTGAGGCCCAACAAGGGTGCAACAAGTTTCCCAGCAAATGCGTCGGCTATTGCGACAGCCCAAATGGCCAAAGGGTTCCGTACGTCGACGTTGATCGACCGTTCACGTGCGAGATATGCCTGAAGAACTATCCGACAAGCTCGGCGCTGGCCAACCACGTCAGGTATCACCGCGGGGATCGACCATACCAGTGTGAGATCTGTTGTAAGGCATTTGCGACAAACTCTCACCTGGTGACTCATCGCCGCACCCACACCGGTGAGCGCCCCTACCAGTGCTCGTTGTGCCGGCGGAGTTTCGCGGACCGCTCGGCATTCGTCAAACACGAGCGGACTCACGGCCCGGATGGCGTTATTATCAAACGGTACAAGTGCGAGGAATGCGGGAGCACGTTTGTCGACTCGTGTGGTTTGAAAAAACACATCCGCATCCACACCGGTGAGCGCCCGTATCACTGCTCCGTCTGCGACAAGTCCTTCTCGACAAGTTCCACGTTTGTCGCCCACAAGAGGATCCACAGTGGGGAAAGGCCCCACCATTGTGAACAATGCTCCAAGGCGTTTGTAACCAAGTCTCACCTCCTGACCCACCGACGTACTCACACTGGTGAGAAACCCTTCACTTGCCAGGCCTGCCACCGCGCCTTCGCGGACGGTTCAAGTTTCCGCCGGCACGAGCGGCTTCACACGGGCGAGAATCGACACACTTGCGATGTCTGTGGGAAGGGGTTCCCCTTTGAGACATCTCTTGCTAAACACAAACAATCGCATGTCCCAGGGACTCCAACTTACGTGTACATGGTGTAG
Protein Sequence: MECCDGVEIINEDEDSNVDKVTQMLPEYFVSVKLENNEVEGCYDKINCATLSSGNSSVDVSPHESLSQTELFNMSERVASSTTAAMQSNNSQNHSVHSNHTPHCFHPSRGPSISDLPPWLPHCYAGQLTSDCTQTSQHFLPQAAYLGHDASQTVPRDQSFVSGLPASYQNSELGAAIVLGLRLSKSAGSRAENPGPSSGIGSLANGDICDSNMFLNYVLNQQRSSGLFLFDAAARSLHSSDTLHHDSPGCEGSSDVGGAESVNKSLNDSLGSARASSHPPMNSTKVANLADDKNSPTHRDVATNTVCKFTPAPQHDQTGNRGGEPAGASSCSETNAHHCKCTHKCPERSSHEQENIKSENARNFCCKCQDGTTAKPVSISLGNCGKSAVYHPQEESDHDQALCHSVFCTQCSLSEAQQGCNKFPSKCVGYCDSPNGQRVPYVDVDRPFTCEICLKNYPTSSALANHVRYHRGDRPYQCEICCKAFATNSHLVTHRRTHTGERPYQCSLCRRSFADRSAFVKHERTHGPDGVIIKRYKCEECGSTFVDSCGLKKHIRIHTGERPYHCSVCDKSFSTSSTFVAHKRIHSGERPHHCEQCSKAFVTKSHLLTHRRTHTGEKPFTCQACHRAFADGSSFRRHERLHTGENRHTCDVCGKGFPFETSLAKHKQSHVPGTPTYVYMV*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01449914;
90% Identity: iTF_01449914;
80% Identity: -