Tdou044372.1
Basic Information
- Insect
- Timema douglasi
- Gene Symbol
- -
- Assembly
- GCA_901482245.1
- Location
- CABEEJ010007577.1:1-2868[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 6.7 1.6e+03 2.2 3.1 2 21 166 185 166 186 0.93 2 14 8.3e-05 0.02 17.6 0.4 2 20 192 210 191 212 0.94 3 14 0.045 11 9.0 0.6 1 23 218 240 218 240 0.98 4 14 0.0029 0.7 12.7 1.4 1 23 303 325 303 325 0.98 5 14 0.0013 0.31 13.8 1.1 2 23 381 402 381 402 0.97 6 14 2.7e-06 0.00064 22.3 0.9 2 23 447 469 446 469 0.95 7 14 0.0016 0.38 13.6 1.0 1 23 476 498 476 498 0.99 8 14 1.5 3.5e+02 4.2 0.2 2 16 500 514 499 516 0.92 9 14 0.0021 0.5 13.2 0.0 2 23 570 591 569 591 0.96 10 14 8.8e-06 0.0021 20.7 0.7 1 23 619 641 619 641 0.98 11 14 7.2e-05 0.017 17.8 0.3 1 23 649 671 649 671 0.94 12 14 0.00078 0.18 14.5 2.4 1 23 689 711 689 711 0.98 13 14 0.0019 0.45 13.3 0.5 1 23 744 766 744 766 0.96 14 14 0.005 1.2 12.0 0.2 1 23 773 796 773 796 0.92
Sequence Information
- Coding Sequence
- NNCCTGTTGCAACCAACTTGTCTCCAGTCCCCTACTCAACCGAACCTCTGGTCGTTATCGCAGATCAAGAAAGAGCCAGGTCAGGGTAGTGTGGTGCAACATAAGACACCTTCGGGGGTACACATCACCTTGCAACAAACTGCCCCTGTCGCTACTACTATTGTCCGGGCTAATCCTCCCCCTGCCCACTCTAATCCTCCATCTGCCCGCTCTAATCCTTTTCTTGCCCAGTCTAACCCTCCTTCCACCAACTCTAATTCTTCTCTTGCCCGTTCTAATCCTCCTACGCGCTCTAATCCTTCTCTTGCCCGTTCTAGCCATCCCGCCCGCTCTAATCCTTCTCCTGCCCGTTCTAATCCTCCCTCCACCCGCTCTAATCCTCCCTCCACCCGCTCTAATCCTCCTCCTGCCAGTTCTAATCCTGCTGTTACCCCCCCTATTGCTTCTCCACAGCCATCCTCCCTCAAAAACGTTCCTTTGGACATCAAACCCCGCAAGTGTAAGACGTGCCACTTTGCCTCCACCAGCCGAGAAGAAATGGACCAGCACCTCTGCTCGTTTCAGATGTCGTGGCAATGTAACGTCTGTCAGAAGTATTTTTATACCAAGAGCAACCTTTTGAGACATAAAGGTGTTTGTAAATCCAAGTCTTACAAATGCACGCAATGTAGATTGAACTTTGGTTCACTCGAAAAGATGGCGCAACACAGAATAATACATACCAAAGTTCTGGCTTATGTTAGAGACGAAGATATGTCTGTCTGTTCCTGCGGCAAAAAGTTTGGGTGCAAGATGATGATGAGGATCCACAAACGGTATCACCACTCCTACCCCAGAACTGAGTCGCCGGCCGGCGCGAGTATTAGGAATGGGACTGATCGATTCTCAGGGAAGGTGAGTTATACTTATACTTGTAATTTTTGCAGGATGGATTTTGACAACGCGGTTAAgctcaaaattcataaaaaaatgcattacaGGCATAATGAGTTGCTCTCTAAGAAAAAAAAGCGCGACGCTCTAAAGGCAGCGGCTGAGGTCGATCACGTGAATGACGCTGAAGCCGAGGTGCCGCCACAAATTGATAAAGAGATTCAAAACAGAATGGGCCACTTTATGCCGGGGGCTTGGAATAATCGCGTTTGTAACCTCTGCGGAATGGGTTTCGATAACGAACGCAAGTTCAAGAACCATAAACGAATGCACTATAGGCTTCGTCGTTCGATGGCAAAAAAGGAGCGCAAAAATTTAGAGGCGGAACAGACGAAAGGGCCAGAGGCCCCCGAACCTGCGCCGTCGACTATGACCAAAGATTCCAAGACCTGGTTCAGGAAGTGCAACTGCAAATACTGCGGGGAAGAGTTTCCGAACTCCTCGGCGTTGATCGCGCACATGCGTCAGAAGCACGCCTTGATGAAACCCACCTTCAAGTGCGAGGAGTGTCACAAGGTCATCATGAACCGCGGAGGTTACATAACTCACATAAAGTCCCACAAGGTGTGCAAGGTCTGTCTGAAGCTGTTCTCGTCGTTGGACCACCTGGCGTACGGGGGAGTCCCGAAAAGGTCTTGCCACAAGTGCTTGCGATGCAACTCTCTCAAATTCACGACCAGGCCGGCGTGGTTGGCCCACTGTAAGATGCATGCGGCTAGTAAGTTGGGCAGGCTATCATCGACCATAGTGAACGCTTCTAGAGCGGCGGTTGTCCCTTGCAGTTTTTGTAACGAGATGTTTCCTGACCCGGCGGCCCTGGTTAGCCATCTCGAGATTCACGTCGGGAACAGCTCTAGTTCGATGGGGGCGACGATGGGAGAGGCGACAGCAGAGCCCAACAAGGTCAACCCTCTGTTAATCTACTCCTGCACGACTTGTGGCAACGCTTTCAGTTCCAAGGACGCTTGGACTCGCCACCAGAAGATGCACGCTACCGGCAGGCACAAATACTACCCTTGTAAAATATGTGGGAAGAAGTTTATATCTTTGGAGACGTTTCAAGCCCATTCCGCCAACCATACGTCTAGTAACCAACCGGAGTCCGTTCCGGCGGCGGAAGCGGGCCCCGAGTTTCCGTGCAAACGGTGTCCGTTTTCTTGCTTCTCGCAACAGGCCCTCAATTCACACATGAGAATTCACGCGCCGTCGAAACCGGCGGGCGAGCTCGTCAACAACGGACAGGTTAAGGTCAATTCGACTAGAAAAAAGATGGTGTTGGTGAAGACGAGCAATGGCTACAAGTGCAGCGTCTGCCCTAAAGTTTTCCCAAACCATTATGCCGGTGCGAGTCATGTAAGGTCACATTTACAGGGACCAAAGAACTACATATGTCCGCTGTGtccaaagaaatataaagaCTCTGAAATTCTTTATAAACACATCTATTTAGATCACCCCGATAATCGGCACTAA
- Protein Sequence
- XLLQPTCLQSPTQPNLWSLSQIKKEPGQGSVVQHKTPSGVHITLQQTAPVATTIVRANPPPAHSNPPSARSNPFLAQSNPPSTNSNSSLARSNPPTRSNPSLARSSHPARSNPSPARSNPPSTRSNPPSTRSNPPPASSNPAVTPPIASPQPSSLKNVPLDIKPRKCKTCHFASTSREEMDQHLCSFQMSWQCNVCQKYFYTKSNLLRHKGVCKSKSYKCTQCRLNFGSLEKMAQHRIIHTKVLAYVRDEDMSVCSCGKKFGCKMMMRIHKRYHHSYPRTESPAGASIRNGTDRFSGKVSYTYTCNFCRMDFDNAVKLKIHKKMHYRHNELLSKKKKRDALKAAAEVDHVNDAEAEVPPQIDKEIQNRMGHFMPGAWNNRVCNLCGMGFDNERKFKNHKRMHYRLRRSMAKKERKNLEAEQTKGPEAPEPAPSTMTKDSKTWFRKCNCKYCGEEFPNSSALIAHMRQKHALMKPTFKCEECHKVIMNRGGYITHIKSHKVCKVCLKLFSSLDHLAYGGVPKRSCHKCLRCNSLKFTTRPAWLAHCKMHAASKLGRLSSTIVNASRAAVVPCSFCNEMFPDPAALVSHLEIHVGNSSSSMGATMGEATAEPNKVNPLLIYSCTTCGNAFSSKDAWTRHQKMHATGRHKYYPCKICGKKFISLETFQAHSANHTSSNQPESVPAAEAGPEFPCKRCPFSCFSQQALNSHMRIHAPSKPAGELVNNGQVKVNSTRKKMVLVKTSNGYKCSVCPKVFPNHYAGASHVRSHLQGPKNYICPLCPKKYKDSEILYKHIYLDHPDNRH*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01445105;
- 90% Identity
- iTF_01445105;
- 80% Identity
- -