Basic Information

Insect: Timema douglasi
Gene Symbol: ECU06_1150
Assembly: GCA_901482245.1
Location: CABEEJ010001730.1:59504-60514[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.1 24 7.9 5.8 3 20 82 99 80 102 0.89

2 8 4.8e-05 0.011 18.4 4.4 1 23 134 156 134 156 0.98

3 8 7e-07 0.00017 24.1 0.7 1 23 162 185 162 185 0.95

4 8 7.2e-05 0.017 17.8 0.3 1 23 191 213 191 213 0.97

5 8 2.5e-06 0.0006 22.4 2.3 1 23 219 241 219 241 0.98

6 8 7.9e-06 0.0019 20.8 2.0 1 23 247 269 247 269 0.96

7 8 7.6e-06 0.0018 20.9 0.7 1 23 275 297 275 297 0.98

8 8 4.1e-05 0.0097 18.6 1.5 1 23 303 326 303 326 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.1	24	7.9	5.8	3	20	82	99	80	102	0.89
2	8	4.8e-05	0.011	18.4	4.4	1	23	134	156	134	156	0.98
3	8	7e-07	0.00017	24.1	0.7	1	23	162	185	162	185	0.95
4	8	7.2e-05	0.017	17.8	0.3	1	23	191	213	191	213	0.97
5	8	2.5e-06	0.0006	22.4	2.3	1	23	219	241	219	241	0.98
6	8	7.9e-06	0.0019	20.8	2.0	1	23	247	269	247	269	0.96
7	8	7.6e-06	0.0018	20.9	0.7	1	23	275	297	275	297	0.98
8	8	4.1e-05	0.0097	18.6	1.5	1	23	303	326	303	326	0.94

Sequence Information

Coding Sequence: ATGGTCTGGATTAAGAGCGAAGAGGGTGAACAAAATGCCTTGGAGGGTTTCATTAGTAGGGGACCGGTGGTGGGTAGAAGCAGCACTGTGGTGCACCTAAAACAATCTCAATCGCTCAGCAACAGTGTTGTTTCTGCCACCTTCAAGACTGATGTGAGGACAAGTCGTAGTGAGAGAAGGTTAAGGAAAATGAAATCTCTTGTTGCAGATGGCAACTCGAAAGAGATGCTTGGGTCTATTTCTTGCGAGTGTTGCAGTAAAAGGTTTACAAGAAAGATCGATCTGAGGAGACATAAAATGTGCCATCTGCAAAACTTTGAGAAGGTATCAGAAGACAACTTGGAAGATGTTACTGACTTGGGGGGTGAAGAGAACATAAGGCGTGTTCagaaatgtttgtttcattGCTCGGAATGTGGTAGAAATTTTACACTAAAGGACAGCTACTTCCGACACCGGCGAATCCACACTGGCGAAAAACCATTCACATGCCATGTCTGCGGAAAACAGTTTCGTGATTCTGGAGGCCTGGCGCGCCACCTTAAGGATGTACATGCCGGTATCAAGAACTTTGCTTGTGACCTGTGCGGGCGAACCTTTGCTTCCAAGGCAACGAAGGAGGATCACCGTCGTATTCACACTGGGGAGCGTCCATACATTTGTCATTCCTGTGGTAAAACTTTCCGCTCTAAGGCGTCTTTGTACATCCATGCCAAGACACACACAGACTTGTACCCACACGCCTGCACATATTGCGATAAACAGTTTCGGCGCCGGCAAGAACTGTTGGCACATGTGAGTACTCATACAGGAGAAAAGCCTTACCCATGCGAAGTGTGTGGGAGGTTCTTTCGTGTTCGTGGGGAGTTGCACAGGCATCGGCTTATTCATTCGGATTACAAAGCGTTTGTGTGTTCCCTCTGTGGCATGAACTTTCGTCAGAAGCGGTATTTAAAGAACCACGAGAAAGCTCGGCACTCTAAACAGGAAGTTGTAACCCACACTAAATAA
Protein Sequence: MVWIKSEEGEQNALEGFISRGPVVGRSSTVVHLKQSQSLSNSVVSATFKTDVRTSRSERRLRKMKSLVADGNSKEMLGSISCECCSKRFTRKIDLRRHKMCHLQNFEKVSEDNLEDVTDLGGEENIRRVQKCLFHCSECGRNFTLKDSYFRHRRIHTGEKPFTCHVCGKQFRDSGGLARHLKDVHAGIKNFACDLCGRTFASKATKEDHRRIHTGERPYICHSCGKTFRSKASLYIHAKTHTDLYPHACTYCDKQFRRRQELLAHVSTHTGEKPYPCEVCGRFFRVRGELHRHRLIHSDYKAFVCSLCGMNFRQKRYLKNHEKARHSKQEVVTHTK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01450882;
90% Identity: iTF_01445074;
80% Identity: -