Basic Information

Insect: Timema douglasi
Gene Symbol: -
Assembly: GCA_901482245.1
Location: CABEEJ010003090.1:57377-66284[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.093 22 8.0 5.9 1 23 186 208 186 208 0.97

2 12 0.029 7 9.6 0.2 2 23 214 235 213 235 0.96

3 12 0.0088 2.1 11.2 0.2 2 23 242 264 241 264 0.94

4 12 4.2e-07 0.0001 24.8 1.0 1 23 277 300 277 300 0.97

5 12 0.066 16 8.5 2.7 1 23 307 329 307 329 0.93

6 12 0.0051 1.2 12.0 0.2 1 20 335 354 335 355 0.95

7 12 5.5e-05 0.013 18.2 1.2 1 23 363 386 363 386 0.92

8 12 2e-05 0.0048 19.5 4.3 1 23 402 424 402 424 0.98

9 12 2.2e-05 0.0051 19.4 0.7 1 23 430 452 430 452 0.99

10 12 0.0026 0.62 12.9 2.2 1 23 458 480 458 480 0.99

11 12 2.6e-06 0.00061 22.4 4.3 1 23 486 508 486 508 0.98

12 12 1.4e-06 0.00033 23.2 0.5 1 23 514 537 514 537 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.093	22	8.0	5.9	1	23	186	208	186	208	0.97
2	12	0.029	7	9.6	0.2	2	23	214	235	213	235	0.96
3	12	0.0088	2.1	11.2	0.2	2	23	242	264	241	264	0.94
4	12	4.2e-07	0.0001	24.8	1.0	1	23	277	300	277	300	0.97
5	12	0.066	16	8.5	2.7	1	23	307	329	307	329	0.93
6	12	0.0051	1.2	12.0	0.2	1	20	335	354	335	355	0.95
7	12	5.5e-05	0.013	18.2	1.2	1	23	363	386	363	386	0.92
8	12	2e-05	0.0048	19.5	4.3	1	23	402	424	402	424	0.98
9	12	2.2e-05	0.0051	19.4	0.7	1	23	430	452	430	452	0.99
10	12	0.0026	0.62	12.9	2.2	1	23	458	480	458	480	0.99
11	12	2.6e-06	0.00061	22.4	4.3	1	23	486	508	486	508	0.98
12	12	1.4e-06	0.00033	23.2	0.5	1	23	514	537	514	537	0.97

Sequence Information

Coding Sequence: ATGAAGGACCACATTTACATCACTTTGCCAAGTGACAGCTCCATGAAATATTTCCTGAAAAATATTCTCTcgaatttcaccacgcaactaACCTACCGTCTTACACTCGGCGGACAGTGGGAAGACTCTCTCGCCGAGTTCTTTCAGAACTGTACTCGAGGGCCAAAATATTGTAAGCCTTTCACAGATGCTTTACGCCAGGctggaacaaacctgaaacCTAAGACGGAGCAGAAGATCGAAGCACTGATGACcggctcaggctataaagggcgtcgtaagaagcaCCGACGTCTTTTATCGTTGCccgacgtaaaaagATCAGAAGAGAACCCGAGATTTGAGGATTATAAGTTTGAGTCAATCAGAAATTTGGAAGAGCAAGGTGGTATGAGATGCATTGTTGAAACAATATATCCAGCTAGTATGAACTATAAACAAGAAGCTTGTGAAATAgtttctcaaaatataaaagagAGATCCAAATTGAAAACAAGAAATGTCACGTCTTGTGATTATCCAAGATCTAGTTTAGCTCACACAAATAAACTAAAGCATTCATGTAACATTTGTCACCAATCTTATCTGACGAGAACTTCGTTAAAAGAGCACACCAAGAATCACACTCAAGAGGAAATAAAGTGTGGCTTGTGTGGTTACCTGCTCAAGAATGAACATGTCCTAAGAGCTCACATGGACATCCATAAGGAGGTCCAGCCCTTACCGTGTGGGCTATGTAACAAAGTTTTTCTCTTTGCCTCGTCCTTGGAGCAACACACAAAGTATGAGCATGAAACCAACAACCCTGTCGAAATAGTATCCGTCTTCTACACGTGCCAGATATGCGGAAAAAGCttcaaaaatttacaaaacctaAGGATGCATGAGAGACAAATTCATCTGGGTATCCCCAAACAGCATATATGCGAGTGTTGTGGTGCAATGTTCTACAGTGGCAGCAAGCTTAGACTACACATGCTGAGACATACGGGTGAGCGCCCCTTTACATGTGAGATCTGCGGGCTGCGTTTTGGCACCAAGCACCGCCTCGGTAACCACCTTGTGTGCCACTCGGAGGCAAGGCCTCACGCATGCGGTGTTTGCGGTAAGACTTTCAAGAGGCAACGTAATCTTGGCATGCACGAGCAGAACTCGCATGGAGTCTTCTCTCAGGGCGCCAGTAAAGAGAAGGTTGTGATCAGCTTCTCATGCCAGATGTGCAAGAAACATTTCACCACAAAGCAGAAGCTGGCGGTGCACATGAGAGAACATACAGGGGAGAGACCTTTTCGCTGCGATATCTGTGGAAAGGTTCTCTCTTCAAAAATGGGAAAGAAAAATCACATCCGCACCCACACTGGTGAACGTCCATATAAATGTAACAGGTGTGAGCTGGCACTTAAAACACACGCTCAACTGTACTCCCATTTACAGACACACTCTGAAAACAAACCATTTTCCTGCTCATACTGTCAGAAAATGTTTCGTCGTAGGCCACATTTAGTCAGCCATCTTCGTACGCATACTGGAGAAAAGCCCTACTCTTGCACTGTGTGCGACCGAGCGTTCTCCCAGAAAGCTGATATGAGGAAGCACATGGACAAAATCCACACCATTCTTGGGAgttccaaataa
Protein Sequence: MKDHIYITLPSDSSMKYFLKNILSNFTTQLTYRLTLGGQWEDSLAEFFQNCTRGPKYCKPFTDALRQAGTNLKPKTEQKIEALMTGSGYKGRRKKHRRLLSLPDVKRSEENPRFEDYKFESIRNLEEQGGMRCIVETIYPASMNYKQEACEIVSQNIKERSKLKTRNVTSCDYPRSSLAHTNKLKHSCNICHQSYLTRTSLKEHTKNHTQEEIKCGLCGYLLKNEHVLRAHMDIHKEVQPLPCGLCNKVFLFASSLEQHTKYEHETNNPVEIVSVFYTCQICGKSFKNLQNLRMHERQIHLGIPKQHICECCGAMFYSGSKLRLHMLRHTGERPFTCEICGLRFGTKHRLGNHLVCHSEARPHACGVCGKTFKRQRNLGMHEQNSHGVFSQGASKEKVVISFSCQMCKKHFTTKQKLAVHMREHTGERPFRCDICGKVLSSKMGKKNHIRTHTGERPYKCNRCELALKTHAQLYSHLQTHSENKPFSCSYCQKMFRRRPHLVSHLRTHTGEKPYSCTVCDRAFSQKADMRKHMDKIHTILGSSK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01448855;
90% Identity: iTF_01445882;
80% Identity: -