Basic Information

Insect: Timema douglasi
Gene Symbol: -
Assembly: GCA_901482245.1
Location: CABEEJ010000223.1:15172-29531[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.54 1.3e+02 5.6 1.1 2 13 477 488 476 496 0.82

2 16 0.13 31 7.5 3.9 1 20 504 523 504 526 0.90

3 16 0.47 1.1e+02 5.8 0.2 2 13 542 553 541 560 0.85

4 16 0.025 6.1 9.8 3.6 1 23 568 590 568 590 0.90

5 16 2.7e-06 0.00063 22.3 0.3 3 23 598 619 596 619 0.95

6 16 0.0011 0.27 14.0 4.8 1 23 625 647 625 647 0.97

7 16 0.00018 0.042 16.6 0.6 1 23 653 675 653 675 0.98

8 16 3.7e-07 8.9e-05 25.0 2.5 1 23 681 703 681 703 0.99

9 16 1.8 4.2e+02 4.0 1.9 1 23 714 738 714 738 0.93

10 16 3.1e-07 7.4e-05 25.2 1.2 1 23 756 778 756 778 0.99

11 16 4.2e-05 0.01 18.5 2.8 2 23 785 806 784 806 0.96

12 16 1.7e-05 0.0041 19.8 3.9 3 23 814 834 812 834 0.98

13 16 0.6 1.4e+02 5.5 0.5 1 23 840 862 840 862 0.93

14 16 0.0013 0.32 13.8 2.8 1 20 868 887 868 890 0.94

15 16 5.6e-08 1.3e-05 27.6 0.3 1 23 896 918 896 918 0.98

16 16 7.5e-05 0.018 17.7 3.9 1 23 924 946 924 946 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.54	1.3e+02	5.6	1.1	2	13	477	488	476	496	0.82
2	16	0.13	31	7.5	3.9	1	20	504	523	504	526	0.90
3	16	0.47	1.1e+02	5.8	0.2	2	13	542	553	541	560	0.85
4	16	0.025	6.1	9.8	3.6	1	23	568	590	568	590	0.90
5	16	2.7e-06	0.00063	22.3	0.3	3	23	598	619	596	619	0.95
6	16	0.0011	0.27	14.0	4.8	1	23	625	647	625	647	0.97
7	16	0.00018	0.042	16.6	0.6	1	23	653	675	653	675	0.98
8	16	3.7e-07	8.9e-05	25.0	2.5	1	23	681	703	681	703	0.99
9	16	1.8	4.2e+02	4.0	1.9	1	23	714	738	714	738	0.93
10	16	3.1e-07	7.4e-05	25.2	1.2	1	23	756	778	756	778	0.99
11	16	4.2e-05	0.01	18.5	2.8	2	23	785	806	784	806	0.96
12	16	1.7e-05	0.0041	19.8	3.9	3	23	814	834	812	834	0.98
13	16	0.6	1.4e+02	5.5	0.5	1	23	840	862	840	862	0.93
14	16	0.0013	0.32	13.8	2.8	1	20	868	887	868	890	0.94
15	16	5.6e-08	1.3e-05	27.6	0.3	1	23	896	918	896	918	0.98
16	16	7.5e-05	0.018	17.7	3.9	1	23	924	946	924	946	0.98

Sequence Information

Coding Sequence: ATGAAGATTGTCTTGAAAAATGGGGATGGAGAAAGCACTACAATTGAGGTGAACCCACAAGATACCTTTTGCGATCTCAAAACTCGGATAAAGAATGAAGCTGGGATTGAGCTGGACTTAGAGCAACTCAAAGTCAATGGAAGAAAGATAACAGATGACCAATTTGTTTCAGAATATTTCTTTAATGatgaagAAAGTAGCACACCTGATGAGTTTGAAACCGAACGAAGCGTTGAAGTCACTTCTTTTTACTGCGCTGTACCAGGATGCAACAGTACACAAGCTTCTTGTCCAGACAAAACCTTCTTCAAGTTCCCAATCTCTGACGACAAATGCCGTCATTGGCTATCAATATGCAAGCGCCATGACTTGATAAGAAAGCCAAGTTCATATGTGAACTATCATTACACTATTTGCTCTGACCACTTCATCGGAGATCATTTTCTGGATACTACAAGGCGAGAACTAAAACATAACGCTGTCCCTACAATATTCAACCAAAATCTCCTGGAAGGTGACAGTTCGCTTTTTTTGGAAGTAAATGACGACTTAGCTAATCAAGACTCgtgtaatattttgataaaaaaagagAGTAGAGGGGATAACGAGTGTTCAGACTCCAATGTGGTGGAGGATGAAGACGAGTACTATGTCTCAGAGCAAGAGTATGAATCAGGAGACACAGAAAGTGGGGATGAAGGAGAGGGGGAACATCCGGGTCAGCTGTGTCGGCTCTGCGCCAAGAATGCGGCAGAGATGTTATACATCTACAGTACTAGTGGCAAGGATCAACTCATAGCTGAGAAGATCAACACTACCTTACCTGTCTCGGTAAGGTTGTCTGACCATCTCCCCAAGCAGCTCTGTGCAGATTGTGTCAATAAACTGAACACATGTCATGAGTTTGCAGAGTCTTGTTTATTGGCCGAAGAGAAACTAACCCATTTAAATAGAAGAAGATTGTTTAGATctgtttctgcaacaattaATGTATCCATGTCAAGAGAGACCGAATGTAAAAATACAGACAGCATACTATCCAACGAGAATAAAAGTGATAgccaaatttttgaaaacaataattactgCTGTCCTCTTTGCTGTAAGGGAAACATGACAGTTCAAAACACAGAAACGGGCGATAAAGATGTAAGAATAGACATATTACGGACACTAGAAGACAACTCTTTACCTGCAAATATGGTTGATGGTGTGACTCAtattactaaactatttattgaCAGCAACGACTCATCCCAATTgaatggtgatgatgatgatgataatagcTCTAATGCATGGGAAATCAAGGATAGTGTTGAAGGGACAGAAATATCAAATGCTGGCAACAATAGTGGTTTGTTCAATCTTCCGATAGAGGGTAACATTTTGATTTATGGAGAAGCTGTGTCAGTGCAAAATGCTTGTATGTGTAGGATATGTGGTGAATCTTTTAAGAATGTAGATTTATGTCTAGCTCATTCCATGTGTCATGCCACGGCAGATTTCTTTCCTTGCAGTATGTGTGATTTGTGTTTTGTGAGTGATTCAAGTTTTAACAGTCATTGCATGGAACACACAGTAAAAGCGAAGCTGTCCGGATTCAGAGTGTCAAAACGGCTGCAGTGCGAGATGTGCAACCGAAGGTTCAACAATGAAAGGACTCACGCAAACCATTCTTGTGAGACAGGAACTCGTCCATATAAGTGTGACCAGTGTGGAAAGTTTTTTAGTTCAGAAGCACGCCTTACTTTCCATAGTCATACACACAAGGGAGCAAATCCCATGATATGTGAGTATTGTGGTAAAACATTCTCCCGCGAAAACAATCTCTTTGATCATGTCAGACTTGTGCACATGGGTGAGAAGGTTCATAACTGTCATTATTGCGGAAAGACTTTTCAGATCAAGACGCGTCTCATTTCACACTTGCGTGTGCATACTGGCGAGCGCCCATTTCAATGTAGCTACTGTGATGGAAAATTTTATGACAACGCAACTTTGAAAGGGCATATGGTGACACACATGAACATAAAACCATTCCAGTGTGATATTTGTGGGCGTTGTTTTGCTAGAAAAACTTTGTTGAAAAATCATTTGTTGACTCATATATTTATGAAGGATTCCCAAAAACGAATTCACAAGTGTAAAATATGTGAGGATTCTACCTTCCCAACGCATGCAAAGTTGGCAGAACATAGAAAGGAAGTACATCCTGAGTTAAGATTTGCAAATAATGACTTTGCTGAAAAGACTTCTAAACCTTTCAAGTGTGAAGAGTGTGGAAAGAGTTTTGCCTATCGTGTCACTCTGACATCTCACCAGCGGAGCCACACGGGGGAAATGCCGTGGCATTGTGAGTTTTGTGGAAAGAAGTTTTCCCAGAAACGTTCTCTAGTGCTTCATCGTCGAATACACACAGGCGAGAAACCATTTGGTTGTCATTACTGCGGGAAGCGGTTCATTCAGAGTGCACACCTTTACTCCCATCAGCGTCTACACACAGGCGAGAAGCCCTACTCTTGTCAGATGTGTGGAGACAGCTTCCGTCTGAAGGATGTACGTGATGCACATGAGCGCAAGCACACAGGTGAACGCCCATTTAAGTGTAATGTATGCGAGAAAACTTTCCGAACATCGCATGCATATTACCAACACACATGGATTCACCAAGGAAAGAAGCCATACCCTTGCAACTACTGTGGGAAAGCCTTCCGCCGCTCCAACGGGCTCAAGATCCATATCCGCATCCATACAGGGGAGAAGCCTTACCGCTGTGACTTGTGTGGACGTTGTTTTGCTCAGAAACAAGAcatgaaaaaacataaaaacttgcACCTACAGGGAAAGCTTTAA
Protein Sequence: MKIVLKNGDGESTTIEVNPQDTFCDLKTRIKNEAGIELDLEQLKVNGRKITDDQFVSEYFFNDEESSTPDEFETERSVEVTSFYCAVPGCNSTQASCPDKTFFKFPISDDKCRHWLSICKRHDLIRKPSSYVNYHYTICSDHFIGDHFLDTTRRELKHNAVPTIFNQNLLEGDSSLFLEVNDDLANQDSCNILIKKESRGDNECSDSNVVEDEDEYYVSEQEYESGDTESGDEGEGEHPGQLCRLCAKNAAEMLYIYSTSGKDQLIAEKINTTLPVSVRLSDHLPKQLCADCVNKLNTCHEFAESCLLAEEKLTHLNRRRLFRSVSATINVSMSRETECKNTDSILSNENKSDSQIFENNNYCCPLCCKGNMTVQNTETGDKDVRIDILRTLEDNSLPANMVDGVTHITKLFIDSNDSSQLNGDDDDDNSSNAWEIKDSVEGTEISNAGNNSGLFNLPIEGNILIYGEAVSVQNACMCRICGESFKNVDLCLAHSMCHATADFFPCSMCDLCFVSDSSFNSHCMEHTVKAKLSGFRVSKRLQCEMCNRRFNNERTHANHSCETGTRPYKCDQCGKFFSSEARLTFHSHTHKGANPMICEYCGKTFSRENNLFDHVRLVHMGEKVHNCHYCGKTFQIKTRLISHLRVHTGERPFQCSYCDGKFYDNATLKGHMVTHMNIKPFQCDICGRCFARKTLLKNHLLTHIFMKDSQKRIHKCKICEDSTFPTHAKLAEHRKEVHPELRFANNDFAEKTSKPFKCEECGKSFAYRVTLTSHQRSHTGEMPWHCEFCGKKFSQKRSLVLHRRIHTGEKPFGCHYCGKRFIQSAHLYSHQRLHTGEKPYSCQMCGDSFRLKDVRDAHERKHTGERPFKCNVCEKTFRTSHAYYQHTWIHQGKKPYPCNYCGKAFRRSNGLKIHIRIHTGEKPYRCDLCGRCFAQKQDMKKHKNLHLQGKL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01447630;
90% Identity: iTF_01445093;
80% Identity: iTF_01446659;