Tdou001946.1
Basic Information
- Insect
- Timema douglasi
- Gene Symbol
- -
- Assembly
- GCA_901482245.1
- Location
- CABEEJ010000073.1:448156-450235[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 2.5e-06 0.00059 22.4 2.2 2 23 98 119 97 119 0.97 2 10 2.2e-05 0.0052 19.4 0.3 2 23 126 147 125 147 0.96 3 10 3.3e-06 0.00079 22.0 4.4 1 23 153 175 153 175 0.98 4 10 5.2e-05 0.012 18.3 1.8 2 23 182 203 181 203 0.97 5 10 3.5e-07 8.4e-05 25.1 0.2 1 23 209 231 209 231 0.97 6 10 8.2e-06 0.002 20.8 0.3 1 23 241 263 241 263 0.99 7 10 0.00031 0.073 15.8 0.6 1 23 269 291 269 291 0.95 8 10 1.9e-05 0.0045 19.6 0.2 3 23 299 319 298 319 0.98 9 10 5.3e-08 1.3e-05 27.6 2.0 1 23 325 347 325 347 0.98 10 10 8.7e-07 0.00021 23.8 3.7 1 23 353 375 353 375 0.98
Sequence Information
- Coding Sequence
- ATGGTCCCGTCAAGTGACGATAGCCCTTGGTTACCggcacaatttttattattaagagtTTTGGTGCCTGGGGCGATATCTGAAAATAAACCAGACAGTTCCGAGACGGACTGGGACGCACAGAAAATAGACCAAAGAGGTCTTTCAAAGAAAAGACACAACCAAAAGAACAAACAGGTCAAAAAACCGGAAAACAATTTGCCGCATCTTAAAAGAAGTGTAAATAAATTTGGCAGGACAGGGTTGGACGACCACGCAACGTTTCACAGCGAGAAAGAATTGTCGACTCAGGTCTGTACAATCTGTTCTAAAAGTTTCTCGACGACGAAGTACTTGCAGCGCCACCTGCAACGCCATTTCGCCGAGAAGACGTTGCCGTGCGAGACTTGCGAGCTCAAGTTTAAGACTCCGTACTTGTTGCGTGTACATCAGAGGCTCCACACGGGGGAGGGGATCTACAGCTGCGATCAGTGCGGGAAAACCTACGTCCACAAGTCTCTTCTGATAAGGCACCTTAAACATCACGCTCAGGAATACTCCGTCTACTGCGACGTTTGCAATAAAGGGTTCTATTCGAACCATCAGCTGGTCAATCATAAAAATACTCACACGGGCGAGCGATCTTTCGTCTGCGAGATCTGCGGCAAAAGTTACAACCGCAACAGCAGCCTGTGGACCCACGTGAAGGGACACAACGAGGACAAGTCCAAGAGGAAGACGTTCAAATGCGAGATCTGCGGCAAAGAGATAACGTCGAAAAGTTCGCTCGACCTCCATATACAGCGTCACAAGGGTGAGCGCAACTTCCTGTGCGACCTGTGCGGTAAGAAGTTCGACAAGCGGATAACGATGGAGATCCACCGGCGGGTCCACACGGGGGAGAGGCCGGAGATATGCAAGGTGTGCGGCAAGGCGTTCGGGAAGATCACGACCCTCGTCGTTCACATGCGTACGCACACCAGTGAAAAACCTTACACGTGTAAAGACTGTGGTAAGAAGTTCACGCAGAGCAGCTCTCTCGTCATCCACAGACGCTACCATACGGGGGAGAGACCGTATCATTGTAACGTGTGCGACAAAAAGTTCGTGTCCAAGTCGCTCCTTAACATGCACCAGAAAACTCATTTCCCTCCTAACAATACGACAGTCAAATGGTAG
- Protein Sequence
- MVPSSDDSPWLPAQFLLLRVLVPGAISENKPDSSETDWDAQKIDQRGLSKKRHNQKNKQVKKPENNLPHLKRSVNKFGRTGLDDHATFHSEKELSTQVCTICSKSFSTTKYLQRHLQRHFAEKTLPCETCELKFKTPYLLRVHQRLHTGEGIYSCDQCGKTYVHKSLLIRHLKHHAQEYSVYCDVCNKGFYSNHQLVNHKNTHTGERSFVCEICGKSYNRNSSLWTHVKGHNEDKSKRKTFKCEICGKEITSKSSLDLHIQRHKGERNFLCDLCGKKFDKRITMEIHRRVHTGERPEICKVCGKAFGKITTLVVHMRTHTSEKPYTCKDCGKKFTQSSSLVIHRRYHTGERPYHCNVCDKKFVSKSLLNMHQKTHFPPNNTTVKW*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01447769;
- 90% Identity
- iTF_01450806; iTF_01447769; iTF_01448799; iTF_01449824;
- 80% Identity
- -