Tdou001902.1
Basic Information
- Insect
- Timema douglasi
- Gene Symbol
- Znf296
- Assembly
- GCA_901482245.1
- Location
- CABEEJ010000073.1:119435-133374[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.00012 0.029 17.1 0.6 2 23 81 101 80 101 0.98 2 11 0.00021 0.049 16.4 0.8 1 23 107 129 107 129 0.98 3 11 3.9e-05 0.0092 18.7 3.3 1 23 135 157 135 157 0.96 4 11 5.3e-06 0.0013 21.4 0.2 1 23 163 185 163 185 0.98 5 11 1.4e-05 0.0033 20.0 2.7 1 23 191 213 191 213 0.98 6 11 1.7e-06 0.00041 22.9 2.2 1 23 219 241 219 241 0.98 7 11 9.6e-08 2.3e-05 26.8 0.4 1 23 252 274 252 274 0.98 8 11 7.5e-07 0.00018 24.0 0.4 1 23 280 302 280 302 0.98 9 11 2.7e-05 0.0064 19.1 0.1 3 23 310 330 309 330 0.97 10 11 6.9e-06 0.0016 21.0 3.9 1 23 336 358 336 358 0.97 11 11 9.6e-06 0.0023 20.6 5.5 1 23 364 386 364 386 0.99
Sequence Information
- Coding Sequence
- ATGTCGCTGAAAGTATCCACTGAAGCCATGAGTGAAAATTTTCACGCGAGCGTCCACTCACCAGCTGAGCGGCTTTATTCCTGCTTGGGGCGTGGCGAGGCGCTGCTTGCTCACTGGATCCACTGTGACCTTTCGAAGAAACAATTGATGGATCACCCACTCATATCCCCCGCCAAATCTCGCCAAAAGTGTGTCAGGAAAGTGAAACGAAGATCACCCAAGAAAAGGCGTGATAGTGGCAAGTGCGAGTTCTGCGGTAAAGGATTTGTTCAAAGTAAGCTGGAGATACACAGGCGCACACATACGGGCGAACGCCCTTTCATGTGTAGTTCCTGCGGCATCACGTTTCTTAGCAACGGCAAGCTCAAATCGCACATGAACACCCACAGCGAGGTGAGGCCTCACGCGTGCACGACGTGCGACCGTAGGTTCAAACGCACCAAGGAGTTGAGTGACCACATGAAGATACACACAGGGGAAAAAGATTTCATATGTAACATCTGCGGGGCGGCATATATACAGAAGTCGAACCTTGTCAATCACAAGAAGAGGCACTTTGGTCACTTCAGTTTCAAATGCCATGTTTGCGACAAGGGTTTTTATAGCAAGACGGAGTTGAAGGAGCACTCAAACATTCACTTGGGCGTGAAACCATTTGTCTGCGAGGTGTGCGGGAAGGCATACCCGTACAAACACAATCTAACCACCCACAAGCGCAAGCACGACCCTAAACACACTGTCTCGCCTAACAAGCACCAGTGTGAGGTGTGCGGGAAGGTGTTTGCCCAGCGCGGGTCCCTCACTCTCCACATGCGTGCACACACGGGACAGGCCATCTTTGTGTGCAACATGTGCGGCAAGTCTCTGTCGAGTAAGGCGTCGCTCACTGTGCATGAACGCACACACACTGGAGAGAAGCCAAACATTTGTGGAATGTGCGGCAAGGCGTTCGCATCGTTAGAGTATCTGAGGATCCATGAGCGCAAACACACCGGAGAGAAACCTCATCGTTGCGATGAGTGCGGGAAATATTTCACTCAGCGCTCGTCGCTCAGCATTCACAAGAGGTATCACACGGGTGACAAGCCCTACCAGTGTCACATAtgtaggaagggttttgtaTCTCAGAGCTTACTACGGACACATCATAAGAGccataataaagataaaaacactcTAAACTTGAACATCAACTCCAATACTGATACAAGTGCATCTGTGATGGAACTTCTGATATAG
- Protein Sequence
- MSLKVSTEAMSENFHASVHSPAERLYSCLGRGEALLAHWIHCDLSKKQLMDHPLISPAKSRQKCVRKVKRRSPKKRRDSGKCEFCGKGFVQSKLEIHRRTHTGERPFMCSSCGITFLSNGKLKSHMNTHSEVRPHACTTCDRRFKRTKELSDHMKIHTGEKDFICNICGAAYIQKSNLVNHKKRHFGHFSFKCHVCDKGFYSKTELKEHSNIHLGVKPFVCEVCGKAYPYKHNLTTHKRKHDPKHTVSPNKHQCEVCGKVFAQRGSLTLHMRAHTGQAIFVCNMCGKSLSSKASLTVHERTHTGEKPNICGMCGKAFASLEYLRIHERKHTGEKPHRCDECGKYFTQRSSLSIHKRYHTGDKPYQCHICRKGFVSQSLLRTHHKSHNKDKNTLNLNINSNTDTSASVMELLI*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01447765;
- 90% Identity
- iTF_01447765;
- 80% Identity
- -