Basic Information

Insect: Timema bartmani
Gene Symbol: hb
Assembly: GCA_902151455.1
Location: CABFWB010001654.1:25228-32685[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.18 41 7.1 1.8 1 23 248 270 248 270 0.98

2 7 0.05 11 8.8 4.4 1 23 273 296 273 296 0.96

3 7 0.0039 0.87 12.3 3.1 2 23 366 387 365 387 0.97

4 7 4e-05 0.009 18.6 4.0 1 23 393 415 393 415 0.99

5 7 0.031 7 9.5 5.8 1 23 421 445 421 445 0.93

6 7 0.00075 0.17 14.6 0.4 1 23 745 767 745 767 0.96

7 7 0.023 5.1 9.9 0.2 1 22 773 794 773 797 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.18	41	7.1	1.8	1	23	248	270	248	270	0.98
2	7	0.05	11	8.8	4.4	1	23	273	296	273	296	0.96
3	7	0.0039	0.87	12.3	3.1	2	23	366	387	365	387	0.97
4	7	4e-05	0.009	18.6	4.0	1	23	393	415	393	415	0.99
5	7	0.031	7	9.5	5.8	1	23	421	445	421	445	0.93
6	7	0.00075	0.17	14.6	0.4	1	23	745	767	745	767	0.96
7	7	0.023	5.1	9.9	0.2	1	22	773	794	773	797	0.90

Sequence Information

Coding Sequence: ATGAATACAACATGTACTCTTCCCAGCAGTTTGACGCATCCTGGCGGTCTTCTGGGGTACGAGGACGGTTCCAGGATGGTTGTGGATACACCTAGTTGGCATCAAACCATGACCTCTATCAAAGAAGAACCATCAGAGGAGCGAGAGCACACTTCACACAGTCCTAACAACGATTCTGGTATTTCTCCGGGTCACGGATCTTCCTGTACCAACAGCGACGGTCCATCTCCTAGTCATGCCACACATACCAACAATGACGTTCAGAGCCCTGTCGGAAGTCCTCAGTCTAGATACACCCTGAACATCCCCCAGCAATGCGTCACTAGACCTTGTACCAACCCTTTCACTCCCGCTGGACCACCGTCCTTCCCAGACAAGGAACTATCCTCTACAAAATCCGTCCACAGTCCAAGTATCACCAACACATCCTCTCCAAACAACACCCCCAACCTTGTTGCTATGACATCAAACCACGAAACAATAGAGATGACGCCTGGAAATTCAACACCTGAAAATAAGAACCAAATTATAACAGTTTCGAACACAAGACTGACGGATGAAAACAGCCACAGCTCATCATCTGCCTCAGAAGGCGAGGGTCTCTACTATAACAGTAAGATGACGTCTGGAGAAGAACTTGATGATTCCTTGCATCGACTCCAGTTAACCTTTGGACACACCCCAGTGATGGAAGGTGGGGATAACGACAAAGTTTATAGTCCAAATGAAGAGAAAACCATTTTTCAATGTCCACTCTGCTCTTTCTCCTCTTTGTACAGGTCCCAGTTCAATAATCACTTAAGTTCCCATTATAATCACAAGTGCTCGTATTGTAACTTTGCAACCAAAGACATGGAAAAGCTTCATACTCATTTGCGTGAGGATCACGACCAGTACATGTCTGCACCTGAGGATGACTGTGAAGGGGATGGGAGCATAGAAGGGGACGAAGAAGAACCAGGGGTGAGGGTTCCTAGGGTCAACTCTCAAGGTAAGGTGAAGACATTCCGCTGCAAGCAATGTAAATTTGCAGCGGTCACCAAGCTTGAGTTCTGGGAACATTCACGCTGTCACATAAAGGTAGAAAAACTTCTTACATGTCCCAAGTGCCCATTTGTGACAGAGTATAAACACCACCTGGAATATCACCTTAGGAATCATTTCAAGTCCAAACCTTTCAAGTGTAACAAGTGCCCATATTCTTGTGTCAATAAATCCATGTTGAACTCTCATTTGAAATCCCACTCAAACATATATCAGTATCGATGTTCAGATTGTACATATGCTACCAAATATTGCCACAGTTTGAAGCTTCATCTCAGGAAATATGCACACAAACCAGCAATGGTCCTCAATCCTGATGGGACACCCAATCCTCTACCAATCATCGATGTATATGGTACTCGAAGAGGACCGAAACAGCGTACCAAAAATTCAGATAGCATAAATGAAAACAACAACTCCTTGATGGCACCCACAACTCAGCCTCAAGCTACCCACCCAATGGGACCCCAATACACCTTGTTCCAGCCTTCATACAGTGTTTTGCAAACTCCTCAACAGTCTTCTTCAAATTTGGCCCTTCCATTTCCATATGGCCCCTTAATCAACAGTTCTTTCCCGCCAACTTCTGATGGGTCTTTGATAAGATTCccaattattaacaaaattcaGCCTTTACGAGATGATGGTGGGAGTACTCTTCAAGAGGGAACAATGTCCTGCTTGAATAAAGTTTTGATTAGTCAgttaaataacaacaataacaacacttCTGATGTCACTGAAAAACATTATATGGCACAGATCTCCTTACAGCAACCAGGAGGTGGTCAGATTAATATTGATGGTATCGGGATGAAGCATATTGGTTCTCCCCTAGACTTGAGTAAGCCTGACACTCCAGAGGTGACAGAGCCTCCTAACACATCTATTAATACAAGAACTGACGGATCACCAACTGCCACTGCAAAGAACCGTAGAAAGGGTAAAGCTTTCAAACTTGAACGAATCGCCATGAAACTCCAACATCAGCAGTCTTCAGAAGAAGAGGAAGAACCTAACATTAAAGTCCCAAAATTAAGGGTTGACAAGGTAATAGAAAACACTGCATCAGTATCAAACACTGCTCCTTCGACACCTGAGACTCTGTCTCAGATTCCTCACGATGAAGATGAACCAGAGAAGAGGAAAGAGCCTGAAAAATCCTTGTGCTCAGATGAACAGGATACTTATAACTGCTCCTATTGTGACATTACATTTAAGGATATTGTGATGTACACAGTGCATATGGGCTATCATGGCTACCAAGATCCATTCACATGtaatatgtgtggacagcagacTCCAGATAAGGTGGCATTTTTTCTGCACATTGCAAGGTCATCGCACATATAA
Protein Sequence: MNTTCTLPSSLTHPGGLLGYEDGSRMVVDTPSWHQTMTSIKEEPSEEREHTSHSPNNDSGISPGHGSSCTNSDGPSPSHATHTNNDVQSPVGSPQSRYTLNIPQQCVTRPCTNPFTPAGPPSFPDKELSSTKSVHSPSITNTSSPNNTPNLVAMTSNHETIEMTPGNSTPENKNQIITVSNTRLTDENSHSSSSASEGEGLYYNSKMTSGEELDDSLHRLQLTFGHTPVMEGGDNDKVYSPNEEKTIFQCPLCSFSSLYRSQFNNHLSSHYNHKCSYCNFATKDMEKLHTHLREDHDQYMSAPEDDCEGDGSIEGDEEEPGVRVPRVNSQGKVKTFRCKQCKFAAVTKLEFWEHSRCHIKVEKLLTCPKCPFVTEYKHHLEYHLRNHFKSKPFKCNKCPYSCVNKSMLNSHLKSHSNIYQYRCSDCTYATKYCHSLKLHLRKYAHKPAMVLNPDGTPNPLPIIDVYGTRRGPKQRTKNSDSINENNNSLMAPTTQPQATHPMGPQYTLFQPSYSVLQTPQQSSSNLALPFPYGPLINSSFPPTSDGSLIRFPIINKIQPLRDDGGSTLQEGTMSCLNKVLISQLNNNNNNTSDVTEKHYMAQISLQQPGGGQINIDGIGMKHIGSPLDLSKPDTPEVTEPPNTSINTRTDGSPTATAKNRRKGKAFKLERIAMKLQHQQSSEEEEEPNIKVPKLRVDKVIENTASVSNTAPSTPETLSQIPHDEDEPEKRKEPEKSLCSDEQDTYNCSYCDITFKDIVMYTVHMGYHGYQDPFTCNMCGQQTPDKVAFFLHIARSSHI*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01446069;
90% Identity: iTF_01451031;
80% Identity: -