Tcom000944.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Timandra comae
Gene Symbol
GIP
Assembly
GCA_958496195.1
Location
OY292353.1:12115731-12126624[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 9.9 8.9e+02 1.3 0.5 2 8 252 258 251 262 0.86
2 12 0.011 0.99 10.6 0.1 2 20 913 931 912 933 0.96
3 12 0.0036 0.32 12.1 1.4 1 23 974 996 974 996 0.98
4 12 0.032 2.9 9.1 0.2 2 20 1104 1122 1103 1124 0.90
5 12 0.00047 0.042 14.9 1.9 1 23 1132 1155 1132 1155 0.97
6 12 0.00078 0.07 14.2 0.7 1 23 1177 1199 1177 1199 0.98
7 12 1.4e-06 0.00012 22.9 4.5 1 23 1206 1228 1206 1228 0.99
8 12 7.9e-07 7.1e-05 23.6 1.7 3 23 1242 1262 1240 1262 0.96
9 12 2.7e-06 0.00024 22.0 0.8 1 23 1268 1290 1268 1290 0.99
10 12 8.7e-07 7.8e-05 23.5 2.5 2 23 1297 1318 1296 1318 0.96
11 12 8.5e-08 7.6e-06 26.7 1.5 1 23 1324 1346 1324 1346 0.99
12 12 0.0072 0.64 11.2 0.1 1 23 1352 1374 1352 1374 0.97

Sequence Information

Coding Sequence
ATGGAAAGTTCTATCGTTGATGCAGCTAAAATTCATATAGGTGCACTAGAGGCATCGAACTGGACAACATGgaaatttaaagtaattatagcACTGCGAGGTCTGAAGATTCTCGATGTAGTTGAGGGCAAACTTATGCCGCCCCAGAAACTAAAAGTGGATGCAGCAGCAGCAGatgtaaaaaagtataaagaaCAAGAGCAAACATATTTGTCAGCGGATAGCGCAGCCTTACTACTCATAACAACAAACCTATCAGAAGAAAACTGCGAAAAAGTAATGAGATACTCAACAGCGAGAGATGTATGGTTAGAATTACATCGACTGTATGATGGCATTTCAGAAAGTAAAGCCTACGACTTATGCATGAAGTTCTTCAGCTATAAGATGCAATCTGGTGGTGACGTGTTAGCGCATGTcagcaaattgaaaaatatctgGTCAGAACTTACCAGGGAACTGCAAAAAGAACACCTGAAGGAAGAGCTGCCAGAACTATTCCTAATTTGTAAGATACTAGATACTTTACCTGAAGAGTACTTCTCGTTTAAGTCAAGCTGGATGATGATGTCAAAAGAAGACAGGACTGTTGAAAATCTAACAACTCAGTTGAGTAACCACGAAAGAGCTTTATCTAGTAGGCATGAAGAAAAGATAGAAGCACTGGTAGTGAGAGACAACAGAGTTATAACAAATAGGAAGAGTAAGATGAGTAAGAATTCTGGAAAAAGTAAGGTGGAAGCGAGCACAGACAAATGTCATTATTGTGGCATGGTTGGTCATAGAATAAGAGGATGCTCTAAATGGATATCCGATGGACGACCACCTAAGCCAAAACCATCAACATCTAAGTCAAAAGGACCTACTAGAAGTGTGAATATGCATATTATGGCAGTGAATCCAAATGATTCTGCTGATAAAGATCACTGGTATGTGGACAACGGAGCTACTAGTCACGTCACGAACAGGGAGGATCTATTCCAGACATTTGAGAGGTTTCACAATTCACACACCGTTACGACAGCTAATGGAGATACAATTAAGGCAGTTGGAAAAGGAATTGTATACATAGAAGCTGATGTAAAGGGTCGTAATGAACAGATAGCACTTAATGATGTATGGTATGTGCCTACAATACAGAAAAACCTATTTTCGGTACTGTCAGCTCAAGACAAGATGTCAAACAGCCTTTTTATGTCTACAACCGAAGAATGCAAATTGTTACAGCATGGAAAAGTGATACTCATTGGACAAAGAGAAAAAGATGGAGGTCTTTATAAGTTAAAAGTAAGAAATATCAGACCTGAATGTCCAATTGAGATCAACAATATTTCAAAAGAGGATCAATTGCAGCTATACCATGAGAGGTTGGCTCATCAAAGCAAATCACATGTGAAGAAGGTGATTGAGAGAGAACTTGGCATTAAGATGAAGCTAGACAAAGAACTATGTGAGAGTTGTAAGTATGGTAACGCACATAAGTTAAAATTTGGAACAAGAGAAAGAGCTACTGAAACAGGGGAGCTAATACATGCAGATGTATGTGGGCCGTTCACTAACTCTTTATCCAAATACAAGTATTTTGTACTCTTCAAAGATGATTTCAGCAAATTCCGCAATATCTACTTTCTGAGAGAGAAATCAGAGGTTCATAAGAAGCTTGAAGTGATGTTAGCTGAAGCAAAGACTGCAGGACATACAGTAAGAGAGCTATTAAGTGATAATGGAGGAGAATTTGATAACGGAAATGTGAGAAGAATACTGGAGTCGTATGGCATAAAGCAAAGATTAACAATGCCACACACGCCAAACCAGAACGGATGTGTAGAAAGAGATAATAGAACCGTTGTGGAAGCAATGAGGACGATGAGGCATGCAAATGACTTACCTGAAAGTCTATGGGCTGAGTTAGTAAATACCGCAGTGTACATACTGAATAGAACGGGCCCTACTCCACTAGATAAGTCACCGTACGAGATCTGGTACAACAAGAAGCCCAGGATTAAGCATTTAAGAGTGATTGGTAGTATTTGCTATGCACACATTCCTAAAATAACGAGAAAGAAGCTGGACAAGAAAGCTATCAAAGGAGTGCTGGTCGGTTACGATAATGACGAAGGTTATAGAATTTGGGTTAAAGAGAAGAACAAAATAGTTCGATCCAGAGTTGTAATGTTTGAAGAAAAGCCTTTGAAGTCTAAAGATGAGACGAAGGAGAgtattcaagaaacaaatcttCAGAAAGGTCTTATCGGTAAAATAGAAATTCCAGAAGTGATAGTTAAACTTGTGAAACCAGATACATTAAAACCAATTAATGATGAAGAAGAGCCCAGTGATGATGAAAGATTCGAAGACTGTGGTTCTGAACATATAGAAAGTGAGGTTGAAAATGAAGAAGTCTTACCAGAGGTACAGCAAGGAGTAGAACCAGAAATACAGATGGACCCAAATGCAGAACCAGAAGAAGAGCAAGGTATGAGACTGAGAGATCGTTCAACATTGAGAGCACCTGTAAAATTTGAAGATTTTGTGATGATGACAGTTGCAGAGTTGAGTGATATGAAAGAACCTCAATCGTTCAGAGAAGCTATGGAATCCAAAGATAAGGAAAAGTGGAAAATAGCTATGGATGATGAAATAAAGTCGTTGAAAGAAAACGAAACATGGGAAATGGTACCTTTGCCTAAGGGAAGAAAGGCTATACCATTTGAATATGAAGACGTCAATGGGACTTACTGTCCTATCTGCGGTACATGTTATGACGGGGCCAACAGTTTATCGAATCATATGTGGGAGTTTCACGCGGATCTAATGGGTACTAAAAAGAAAGGAAGaccaaagaaaatattgaccACGacaATTCTGAATAAGCTATcagaaaatggtttttttatttcaaccaTTCAAGGAAAAAACTTTCAATGTGCATTTTGTAAGGTTAACTCGAAAACCAAAGATGACCTGAGTAATCACATGCAGCAACATAAAGacacaaaattgttttgctgtatattatgtaaaaaaatgtttttgaagaaaaaatattatgatatgCATAATTGTACCGAagattcaaatttaaaaaaacttgttacaAATCACATGGACAGCgaTATTCCTGACACACAAGCTACCAAATATAAGTTGGCATTCGCAAGTGAAATGACATTACAAGACCTCCAAGATCCAGACAGTGATTTGGACAGTGCTAATTTGATACAAGTTTGCAGCGCATGCAGTGGTGTATTTCTGTCTGAAGGAGATCTCATTAATCATCATGACGCCGAACATCCGGAGCTCTCCTTAAGATGTAATCATTGTACAAAGGTATTTGCGTCTGTAAAAACAGCTGCTCGTCATAGAATAATTTGTAAGCAAGTAGAGAGAACACATAAGTGTACAACTTGCGGCCTTAAATTTGCTTACGAAATATCGCTCaataaacacattttgcgatatCATCAAGGGCAAAGCGTGTCCGTCGCATTCCTCAGTAAGAAACCTAAACAAGTTGGTAATGTGCAATATCAATGTGATTCCTGCAACAAACTGTTCCAAAGAAAAGAAGCTCTAGCAAAACATGCCAAATTGCACTTGGCCAATCAAAAGCTTTACGAATGTGATATTTGTCACCGCAAGTTTAACAGAAGTGATAATTTACGTACTCACAAACGAACCCATGACGTGGACCGGACAAAGCCGCCACCCAATAACTGTTTGTGCCTGTACTGCGGCAGAGGATTCTCCAATTCGTCTAATCTTATAGTCCATATGCGTAGGCACACTGGGGAGAAACCATACAAGTGCGATTTTTGTGAAAAAGGGTTTCCTAGATCGTCGGATCTCATGATTCACAGAAGATCACATACTGGCGAGAAACCGTGTGTCTGTCGAATATGTGGCAAAGCATTTTCCCGAAGCAATAAACTATCCCGGCACATGCGCGTTCACACTGGTCAGCGGCCATATAAGTGCACCTACTGTGATAAGGCATTTTCTCAGAGCAACGATTTGACCTTGCACATCAGGCGTCACACCGGCGACCGCCCCTACATCTGCGAGGTGTGCGGTGACAGATTCATTCAGggAACTGCTCTACAGAACCACAGGAGGGCTCATGGTCACTACCCGGTGCCTCACCCAGACCCCTCCAACCAGGTGCAGGCCATCACTTACAATGTATCTAATATGACTCACGAGCCGCACTTGCCTAACTAG
Protein Sequence
MESSIVDAAKIHIGALEASNWTTWKFKVIIALRGLKILDVVEGKLMPPQKLKVDAAAADVKKYKEQEQTYLSADSAALLLITTNLSEENCEKVMRYSTARDVWLELHRLYDGISESKAYDLCMKFFSYKMQSGGDVLAHVSKLKNIWSELTRELQKEHLKEELPELFLICKILDTLPEEYFSFKSSWMMMSKEDRTVENLTTQLSNHERALSSRHEEKIEALVVRDNRVITNRKSKMSKNSGKSKVEASTDKCHYCGMVGHRIRGCSKWISDGRPPKPKPSTSKSKGPTRSVNMHIMAVNPNDSADKDHWYVDNGATSHVTNREDLFQTFERFHNSHTVTTANGDTIKAVGKGIVYIEADVKGRNEQIALNDVWYVPTIQKNLFSVLSAQDKMSNSLFMSTTEECKLLQHGKVILIGQREKDGGLYKLKVRNIRPECPIEINNISKEDQLQLYHERLAHQSKSHVKKVIERELGIKMKLDKELCESCKYGNAHKLKFGTRERATETGELIHADVCGPFTNSLSKYKYFVLFKDDFSKFRNIYFLREKSEVHKKLEVMLAEAKTAGHTVRELLSDNGGEFDNGNVRRILESYGIKQRLTMPHTPNQNGCVERDNRTVVEAMRTMRHANDLPESLWAELVNTAVYILNRTGPTPLDKSPYEIWYNKKPRIKHLRVIGSICYAHIPKITRKKLDKKAIKGVLVGYDNDEGYRIWVKEKNKIVRSRVVMFEEKPLKSKDETKESIQETNLQKGLIGKIEIPEVIVKLVKPDTLKPINDEEEPSDDERFEDCGSEHIESEVENEEVLPEVQQGVEPEIQMDPNAEPEEEQGMRLRDRSTLRAPVKFEDFVMMTVAELSDMKEPQSFREAMESKDKEKWKIAMDDEIKSLKENETWEMVPLPKGRKAIPFEYEDVNGTYCPICGTCYDGANSLSNHMWEFHADLMGTKKKGRPKKILTTTILNKLSENGFFISTIQGKNFQCAFCKVNSKTKDDLSNHMQQHKDTKLFCCILCKKMFLKKKYYDMHNCTEDSNLKKLVTNHMDSDIPDTQATKYKLAFASEMTLQDLQDPDSDLDSANLIQVCSACSGVFLSEGDLINHHDAEHPELSLRCNHCTKVFASVKTAARHRIICKQVERTHKCTTCGLKFAYEISLNKHILRYHQGQSVSVAFLSKKPKQVGNVQYQCDSCNKLFQRKEALAKHAKLHLANQKLYECDICHRKFNRSDNLRTHKRTHDVDRTKPPPNNCLCLYCGRGFSNSSNLIVHMRRHTGEKPYKCDFCEKGFPRSSDLMIHRRSHTGEKPCVCRICGKAFSRSNKLSRHMRVHTGQRPYKCTYCDKAFSQSNDLTLHIRRHTGDRPYICEVCGDRFIQGTALQNHRRAHGHYPVPHPDPSNQVQAITYNVSNMTHEPHLPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-