Basic Information

Insect: Thymelicus lineola
Gene Symbol: zfh1
Assembly: GCA_963932265.1
Location: OZ010688.1:448323-462779[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0069 0.65 11.5 0.4 1 23 103 125 103 125 0.97

2 8 6.9e-06 0.00065 20.9 3.2 1 23 136 158 136 158 0.98

3 8 2e-06 0.00019 22.6 6.2 1 23 167 189 167 189 0.99

4 8 0.00014 0.013 16.8 1.0 1 21 195 215 195 216 0.95

5 8 0.0056 0.53 11.8 0.3 2 19 479 496 478 499 0.96

6 8 1.1e-05 0.001 20.3 1.1 1 23 801 823 801 823 0.94

7 8 0.00025 0.024 16.0 7.3 1 23 829 851 829 851 0.98

8 8 0.075 7 8.2 7.1 1 21 857 877 857 878 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0069	0.65	11.5	0.4	1	23	103	125	103	125	0.97
2	8	6.9e-06	0.00065	20.9	3.2	1	23	136	158	136	158	0.98
3	8	2e-06	0.00019	22.6	6.2	1	23	167	189	167	189	0.99
4	8	0.00014	0.013	16.8	1.0	1	21	195	215	195	216	0.95
5	8	0.0056	0.53	11.8	0.3	2	19	479	496	478	499	0.96
6	8	1.1e-05	0.001	20.3	1.1	1	23	801	823	801	823	0.94
7	8	0.00025	0.024	16.0	7.3	1	23	829	851	829	851	0.98
8	8	0.075	7	8.2	7.1	1	21	857	877	857	878	0.96

Sequence Information

Coding Sequence: ATGGTCGCGAGAACCGATGAGATGTTCGGCTGCTACGGTGACAGCTACTCGTATCGCCTGTGGAGTCTGGCCAACGTGTGGGGCGCCTGCCGATTGCAGGGCCCGCTTATGGGAGTCGGCGGATGGTACGAACGGTTGGCGGCCGGCTGGCTTGCCGACATGCGGAGTAAGCAGGTCCCGACTTCCACCACTTCGGCCAGGCGGCTCGCGGCCACCATCCGGCCGCTAGCCGGCGGTGGCTCCGAGGGTAAACCTTCGGAGGAGGAGGAGGATCGCGGCGGGTCCCCCCTGGGACCCGGGGGCCCCTTCTCCTGCAGCCAGTGCCGCGGCGCGTACCCCACGCGCGAGCAGCTCGAGCGCCACGAGAAGCTGCACTCCCCCAACACACAGGTGGATAAAGTCAAATATACATGCAAGATCTGCCACAAGAGCTTTATCAACGTGTACCGCCTCCAGCGACACATGATTAGCCACGATGAGAGCGCCCGCCTGCGAAAGTTCAAATGCAATGATTGCGACAAAGCATTCAAGTTTAAACATCACCTCAAGGAGCATCTGCGTATTCACAGTGGAGAGAAGCCCTTCGAATGTGCCAATTGTGGGAAAAAGTTTTCACATTCTGGCTCCTATTCGTCTCACATGACCTCCAAGAAATGTCTTGTGATGAACTTAAAAATGGGAAGAATAAAACCGAACAATCCTGCGCTTAACCCCGATCGAAGTCCTTCGAGAAAGCGATCGAATGCCATGGTTGCCTCGCAGCTCAATAACAATATAACACCAAATAGTAATTCATTTTTACCTACCTTACCTAAATATAATACTGCAGCGTTCTTTGCATGGACGCCAACGCAAGACAATAATTTTACCCAACCAGCGCTACCCCAGCCAGGTATGAATCCTTTCTACATGCCACCCGGAGTACCCATGAGTCCCACGACGGGTATTGCACCTTATACTATTCCGGCTTCTATAGGTCAATTTTTTGCGCAGCTAGCATCCTCGCAATACCCACTTAGAAAAATTGACAAACCTTTGAGCCCTAGCCAACACGGTATTCCTTCAGGAGATCCTGAAGATTTAATAGAAGAAGTCACTGAAGAAGATGATAAAAGATCAGAAGGAAGCGCTGAGCTAGTAATGGATATTGAAGATGATGCAATATCAGTAAAAAAGGAACAAGAAGACCTAGAGGCAGAGCCCAGGTCTCCTCATAATTTTGAATCCGTCCCTATGCCTGAAAACGAACATGAATCCGGTAATGATCATGCAGGATTCAATACAATATTGGACTCAGTTAGTGCATCCGTGACAAAGCATTTTTTTAGGGCAAACATGGAAAAGCTTTCTCCAGTTTCCGGAAACATTTGTCCGAGCTTAGAATCATCGCCTGCTCAGCATATtgtggttaaaaataaattcgcGGATACAAACCAATGCTCAAAATGCAATGCTACGTTTAGCACTATTGATGAATTAATCAAACATGATAAAACTGAATGTGAAAACATATTTAGAAAACACGAAAGCTTAGCAGCTCAAGTTGCAGAAACAGTAGCTTTAAATAGATTGGAAGCTGAAATTCGGGCATCTATGCAAAGTGGTGTTAGTGCTAGCGAAGATGAAGATTTCAGTAGGGACGAACGCGAGGATAAAACTTCTTTGAATGACTCAGACAGAAAGATCAGAGTACGTACTGCGCTAACAGAAGAGCAACAGGTAATACTAAAGGAACATTACATGATTAATCCGAGACCAAATAGAGAAGAGTTTAAGAAAATCGCTCAGAGAATTGGACTTGATAGTAGAGTTGTGCAGGTCTGGTTTCAAAATAACAGAGCGAGGGTGCGAAGAATGAATCAAACGGTTCCAATATCTGACCAGCCATTGGATctttctacaaaaaaatcaaatatatcTGTGACGTCAAGTCCTTCACCTTCGCCACCTTGCAGCATTTCAGTAACACATTCCGACTCTGAGGAAGCGGTAAACCTGAGTCAAAAGTCGTCTCGCAGTACAACCCCGCACCATACACAATATTTAAACACGTATCCACATTCCAACTGTTCATCTTCGTCGTATACCGACTTTGGATTATCACCCTCACCCGGAGAGAATTTAAATGGTCACAAAAGGCCATTACCTcaaaaaatacctataaatCCAATCTTACCCATGGACAAACTCCTACAGTATAATGATCTTGCGAATGCTAGATCTCCCATCCTGAACAAACACGTGCCGGCTGACACTAACTGGCAAGGATCGAGCCCCTCGTATGAAAGGAATTCTTGGGGCGACGAACTGCAAACTCCAACTGAATTCGACGATAAAACATTAGTATTTAAGAAAACTAAGCTGAAGAAAAACGCTGAATTTAAAGAAGGCGAAGGACAATTTGTATGTGACCAGTGCGACAAAACTTTCGTGAAACAAAGTTCACTGGCGCGACATAAATATGAACACTCAGgTCAACGTCCGTACAGATGTCTGGAATGTCCGAGGGCGTTTAAGCATAAGCATCATCTGACCGAGCACAAGCGGCTCCACACCGGAGAGAAGCCCTTCCAGTGCTGCAAGTGCCTCAAGAAGTTCTCCCACTCCGGCTCCTACAGCCAGCACATGAACCACAGGTTCGCCATCTGCAAGCCCTACAGAGATTGA
Protein Sequence: MVARTDEMFGCYGDSYSYRLWSLANVWGACRLQGPLMGVGGWYERLAAGWLADMRSKQVPTSTTSARRLAATIRPLAGGGSEGKPSEEEEDRGGSPLGPGGPFSCSQCRGAYPTREQLERHEKLHSPNTQVDKVKYTCKICHKSFINVYRLQRHMISHDESARLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPDRSPSRKRSNAMVASQLNNNITPNSNSFLPTLPKYNTAAFFAWTPTQDNNFTQPALPQPGMNPFYMPPGVPMSPTTGIAPYTIPASIGQFFAQLASSQYPLRKIDKPLSPSQHGIPSGDPEDLIEEVTEEDDKRSEGSAELVMDIEDDAISVKKEQEDLEAEPRSPHNFESVPMPENEHESGNDHAGFNTILDSVSASVTKHFFRANMEKLSPVSGNICPSLESSPAQHIVVKNKFADTNQCSKCNATFSTIDELIKHDKTECENIFRKHESLAAQVAETVALNRLEAEIRASMQSGVSASEDEDFSRDEREDKTSLNDSDRKIRVRTALTEEQQVILKEHYMINPRPNREEFKKIAQRIGLDSRVVQVWFQNNRARVRRMNQTVPISDQPLDLSTKKSNISVTSSPSPSPPCSISVTHSDSEEAVNLSQKSSRSTTPHHTQYLNTYPHSNCSSSSYTDFGLSPSPGENLNGHKRPLPQKIPINPILPMDKLLQYNDLANARSPILNKHVPADTNWQGSSPSYERNSWGDELQTPTEFDDKTLVFKKTKLKKNAEFKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYRCLECPRAFKHKHHLTEHKRLHTGEKPFQCCKCLKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00795950;
90% Identity: iTF_00971109;
80% Identity: iTF_01438784;