Basic Information

Insect: Thymelicus acteon
Gene Symbol: topi
Assembly: GCA_951805285.1
Location: OX638224.1:3337960-3349217[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.00044 0.042 15.2 1.7 1 23 213 235 213 235 0.99

2 11 0.0022 0.2 13.1 3.4 2 23 243 264 242 264 0.97

3 11 0.042 3.9 9.0 0.5 2 23 269 290 268 290 0.96

4 11 0.00022 0.021 16.2 3.6 1 23 295 318 295 318 0.95

5 11 0.021 2 10.0 0.1 2 23 323 345 323 345 0.95

6 11 0.01 0.99 10.9 0.3 2 20 356 374 356 376 0.95

7 11 0.0011 0.11 13.9 0.3 3 23 386 406 384 406 0.97

8 11 0.13 12 7.5 0.4 2 20 421 439 420 443 0.94

9 11 9.3e-08 8.8e-06 26.8 0.3 1 23 458 480 458 480 0.99

10 11 6.4e-06 0.0006 21.0 0.3 1 23 486 508 486 508 0.98

11 11 2.1e-06 0.0002 22.5 0.2 1 23 516 538 516 538 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.00044	0.042	15.2	1.7	1	23	213	235	213	235	0.99
2	11	0.0022	0.2	13.1	3.4	2	23	243	264	242	264	0.97
3	11	0.042	3.9	9.0	0.5	2	23	269	290	268	290	0.96
4	11	0.00022	0.021	16.2	3.6	1	23	295	318	295	318	0.95
5	11	0.021	2	10.0	0.1	2	23	323	345	323	345	0.95
6	11	0.01	0.99	10.9	0.3	2	20	356	374	356	376	0.95
7	11	0.0011	0.11	13.9	0.3	3	23	386	406	384	406	0.97
8	11	0.13	12	7.5	0.4	2	20	421	439	420	443	0.94
9	11	9.3e-08	8.8e-06	26.8	0.3	1	23	458	480	458	480	0.99
10	11	6.4e-06	0.0006	21.0	0.3	1	23	486	508	486	508	0.98
11	11	2.1e-06	0.0002	22.5	0.2	1	23	516	538	516	538	0.98

Sequence Information

Coding Sequence: ATGGGGCACATTACGTTCTGCTTGATTTGCTTGAGAACAGAAGTGAAGATGTATTCTATGAATTCTATGATGATGAGGATGTACAATGAGCTGATATCATGTCCAgTATCAGAACAATTTTTGAACAGCATTGATCGAAAGCAACATAAATTAGAAACAGTGCTGACTTCATGTACAATAACTCATGACTATCAACCCAAACAAGAATATGAATCACATGAGGAGTTTGAGACTGAGAAAGTTAAATCTGATCCAATTACTTTTGATAACAATTTAACCAATTATGAAGATGATCCTTTACAAATGCAAGGAATGCAGCTCGATATTAAAAATACTGCGGAAAGTGTTATTGAACATGAGCAACTGTTGGATATAAAAAATGATTACCATATTTTAGATGATGTAAATACAACAGAACATGACATCAATGATTACCAATTCACACATACATTTCAAGTAGAAAATTCCAACTATAAATCAGATACTGATAGTATGCTTTGGTTAACCATTCAAAATTCCAAGTTAAACTCCAAAACatcaaaagataatattatgactGTTATTGAATTGACACCAGATGAAATACAGCGTGAATTTCTTCTAAGAAAGAAATCAagtaattacataaataatccTTACAAATGTGATTTATGTTACCGGGGATTTATTTCTAACAATTCATATGAATCTCATTTGAAGAAACACAGTTTGAAACATGGAGCCTTACAATGTGATATCTGCAAATTGTGTTATACTAACACAATCACACTCAGCAAACATCGGAAAATgcacaaatttaaaatttcatgtaaTATTTGTACATACGTTTGCTCTAATCTggGTCAAAGTAATGCCCATATCCTGTCACACAGAGGCAAGGAGTTTACATGTAAGGAATGTGGGATGACTTACAGgtatCGCAACAGTCTTTTAACGCACATGCATTTAAAACACAGCGTGGAACGTGTATGTGAGTTCTGTGGCAGCACATTTGCATCAGAAAAAGGATTGGCTCTTCATAAGCAGATTATACATAGACAGGAAGAAAATAAGCACCTAGGTCCGCAATGCGACGAGTGCGATGTACACTTCACCTCTGAGCGGGCGTGGAAGAGGCACCGCGTGCTGTGCTCCAGACACGAAGTACAGTTCGGCTGCAAGGTCTGCGGCGATGAGTTCACGGACTCTGACAGTTTAAAGCAACACTCGCGTGGTCATGTCGAGGACATTCACTGGTCTAAACAAAAGTATTGTATCCAGACTTGCGTCTTtTGTAAGCGAATGTTGCCCAACAAAGTAGCTTTAAAGAAACATCTATGGAATGAGCACCCAACGGAAACCAGTGGCCAGTTAAAATCGGTGTCCTACAAGTACGTTTGTGAGTTCTGCGGCAAGGCGTTTACACAACCTTCCACCCTTGCCTTGCATCAGAGAAAACACTCAGACGAGATGCCATACAGTTGCCCCGACTGCGGAATGAGAACTAGGTATAAGGAAACCTTGACAGCGCATCTGAAGATACATACCGGCGAGGATGATGATAAGTTTCAGTGTGATTTGTGTGGGAGGCCGTTCAGCGATAAAGGTAGACTCGCCAGACACATAAAGGGTCACATGGGTATTCGACCGTTCAAATGCGTCGCTTGTGACAAAACATTCATGTTTCGGTGTGACGAGAGAAATCATTACAAGCATGTGCACGACAAGGTGCCCTACCCCAAAAAGAATGATGATCCTAAAAAGAAACGTAAGACAAAGGGACCCTTTGCGAAAATACAAATCTTAGATAATATCTAG
Protein Sequence: MGHITFCLICLRTEVKMYSMNSMMMRMYNELISCPVSEQFLNSIDRKQHKLETVLTSCTITHDYQPKQEYESHEEFETEKVKSDPITFDNNLTNYEDDPLQMQGMQLDIKNTAESVIEHEQLLDIKNDYHILDDVNTTEHDINDYQFTHTFQVENSNYKSDTDSMLWLTIQNSKLNSKTSKDNIMTVIELTPDEIQREFLLRKKSSNYINNPYKCDLCYRGFISNNSYESHLKKHSLKHGALQCDICKLCYTNTITLSKHRKMHKFKISCNICTYVCSNLGQSNAHILSHRGKEFTCKECGMTYRYRNSLLTHMHLKHSVERVCEFCGSTFASEKGLALHKQIIHRQEENKHLGPQCDECDVHFTSERAWKRHRVLCSRHEVQFGCKVCGDEFTDSDSLKQHSRGHVEDIHWSKQKYCIQTCVFCKRMLPNKVALKKHLWNEHPTETSGQLKSVSYKYVCEFCGKAFTQPSTLALHQRKHSDEMPYSCPDCGMRTRYKETLTAHLKIHTGEDDDKFQCDLCGRPFSDKGRLARHIKGHMGIRPFKCVACDKTFMFRCDERNHYKHVHDKVPYPKKNDDPKKKRKTKGPFAKIQILDNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -