Tact022795.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Thymelicus acteon
Gene Symbol
Prdm5
Assembly
GCA_951805285.1
Location
OX638230.1:1294878-1303265[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00017 0.016 16.5 0.9 1 23 96 118 96 118 0.97
2 10 4.4e-05 0.0041 18.4 1.2 2 23 124 145 123 145 0.97
3 10 1.3e-07 1.2e-05 26.4 1.4 1 23 151 173 151 173 0.98
4 10 4.2e-05 0.004 18.4 0.1 1 20 179 198 179 200 0.96
5 10 7.6e-06 0.00072 20.8 1.6 2 23 212 233 211 233 0.97
6 10 4.1e-07 3.8e-05 24.8 0.5 1 23 239 261 239 261 0.99
7 10 6.3e-05 0.006 17.9 2.3 1 23 267 289 267 289 0.98
8 10 6.8e-06 0.00065 20.9 3.8 1 23 295 317 295 317 0.98
9 10 7.1e-05 0.0067 17.7 0.6 3 23 325 345 323 345 0.96
10 10 9.8e-05 0.0093 17.3 1.5 1 23 351 374 351 374 0.93

Sequence Information

Coding Sequence
ATGGAAATAGATACGTTTGACGCTACgGTAAAACAAGAACACACTTCAGATTCAGAAGAAGATGCTCAACCTTTAAGTTGGCACAAGCCCTTGAGTGACTCCGGCCAGACAGCCAGGGTGACCAATGGACAGATATTTGAAGTAGAAATCAAACAAGAGACTATTGAAGCAGACTCTGAACCCAATACTCAAGGAAATCAAATGTTGGAGATATCCTTCCAGGACCAAACATTAGTTGAGGGGGAAGATGAAGCACTAACCCAGAACTCTACCCCGGACGGTAAATACATGTGCCCCGTGTGTCACAGTCGCTTCGCTACAAAAGGACTCGTCCAACGCCACCAGCTCTTGCACACCAATGAGAAGCTACAATGTCATATTTGCTTGAAGAATTTCATTAAAGCGGCATATCTGAAGAAACACATCCTGTCTCACTCGACCGTCAAGTCCTACGACTGTCCGGAGTGTGGGAAGCAATTTAAATCGACATCCAATCTCAGCCAGCATCGGAAGACACATCTGGAAATAAAGCCGTTCCAGTGTGAGTTGTGTGACAAGCAGTTTGCGGTCCGAGCCAACCTGATCAAACACCAAGGGAAGAGCAGATGCAAACGCTCCTCGGACCAGCCGATAGTTTGCACCGTATGCAATAAGACTTTTAAGAAAGAGTTCCTCCTGCGAAGTCACCTTCGAAGACACACGACAGAGAAGCCGTACCAGTGCGAGATATGTAACGTGAGCTTCAAGGACAAGTTGTCGTTGATCCGACACATCCAGACGCACAACGGGGTGCGGCCGTACTCCTGCAAGATCTGCCAGAAGACGTTCACCCACGCCGGGCTCATCAAGCCGCACATGAGGAAGCACACGGGCGAGAAGCCCTACCCGTGTCCCGTGTGCAAGAAGATGTTCGCGCACAAGCACAACATGGAGCGCCATACCCTGAGACACAACAAGGTGAAGAACCTCGACTGTGTGATCTGCCAAAAGAGGTTCCCGAAGGAGAGCCGACTGCGGTACCACATGCGGATCCACACGAACGAGAAACCGTTCGCTTGCAAGGTGTGTCCGAAGAAGTTCTCTTACAAGCAGAACGTGATCCGGCACTACGGCAGGAAGCACCCTGGGAAGACGTTCGACTGCGAGATCACGGACGCCAGCTTCGCGCGCGACGTGTGGGAGTCCGTGCTCAAGACCAAGGAAGTGACTATAACGGTGGAACAGTGTGAACCAGTTGAGTCTTGTGAGAGTAATGACGAATATGTCATACCTTGA
Protein Sequence
MEIDTFDATVKQEHTSDSEEDAQPLSWHKPLSDSGQTARVTNGQIFEVEIKQETIEADSEPNTQGNQMLEISFQDQTLVEGEDEALTQNSTPDGKYMCPVCHSRFATKGLVQRHQLLHTNEKLQCHICLKNFIKAAYLKKHILSHSTVKSYDCPECGKQFKSTSNLSQHRKTHLEIKPFQCELCDKQFAVRANLIKHQGKSRCKRSSDQPIVCTVCNKTFKKEFLLRSHLRRHTTEKPYQCEICNVSFKDKLSLIRHIQTHNGVRPYSCKICQKTFTHAGLIKPHMRKHTGEKPYPCPVCKKMFAHKHNMERHTLRHNKVKNLDCVICQKRFPKESRLRYHMRIHTNEKPFACKVCPKKFSYKQNVIRHYGRKHPGKTFDCEITDASFARDVWESVLKTKEVTITVEQCEPVESCESNDEYVIP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01438235; iTF_01439234;
90% Identity
iTF_01438235;
80% Identity
-