Tsen001638.1
Basic Information
- Insect
- Thumatha senex
- Gene Symbol
- PLAGL2
- Assembly
- GCA_948477245.1
- Location
- OX419746.1:9790680-9792242[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 7 5.5e-05 0.0055 18.0 1.0 1 23 109 131 109 131 0.97 2 7 8.6e-05 0.0087 17.4 1.8 1 23 137 159 137 159 0.96 3 7 9.9e-08 1e-05 26.7 1.2 1 23 165 187 165 187 0.97 4 7 0.027 2.7 9.6 2.3 1 23 194 218 194 218 0.94 5 7 0.00041 0.041 15.3 0.2 2 23 226 247 225 247 0.97 6 7 1.6e-05 0.0016 19.7 1.5 1 23 261 283 261 283 0.97 7 7 1.4e-05 0.0014 19.9 1.1 1 23 289 312 289 312 0.94
Sequence Information
- Coding Sequence
- ATGGCCAGTCCGCCACCGAACCCTAAGGAAGGCGAGGAGGGCGACCCCGAGTACCAAGAGGAGTCGAGCGGGGAACGCCCGCCCACCCCGCCGAAGAAGCTCATAGCGCCGCCCGCGTCGCAGCTGGATTCGAAGCTGCAATACGTCACGCTCGGCGCCCCCGGGCCCAGCGGCATCAAGCAGTTGTTCCGTACGGTAAAGGTCGCTCGTCGCGTGCCCACACTGCCGCGCAGGCCCAGGGAGGGTGAGGGCGGCTCCGGGGGCGCCAGCACGTCGGCGCCGCCCGTTCCTGCATCCCGCACGCGCCGCGACCATGCCAAACGCCATGTCTGTGAAACTTGCGAGAAGCGCTTTTCCAGTCCTGGCAAGCTCAGTCAGCATGTCCTGTCTCATACTGGTGAGCTACCATTCTCCTGTGATCTATGTGACAAGCGTTTCAACTCCAAGTTCAAGCTAGTGCGTCATAATCTTATTCACAGTGAGTCTCGAGCCTTTGCGTGTGCTGTATGTGGTAAGACATTTAACCGTAAGGATCACCTCACTAATCATGTTAGAGTGCACAATCCAGTAAAAAAGTTGTTCACCTGTGACAAGCCAGACTGCAGGAAATCTTATACATCTCATCTAAGTTACAGGAAACATGCTGCTTTGCATTCAGCTGAAGAGGGTGACCTACAGTGTAAAATATGTGATATGACTTTTGCCACACGACAGGAAATAGTTTATCATTTAAAAGTTCACACAGGTAGTCGAACTGTTAAGAATGATTCTGATAAAAAGTTCACATGCAATTATTGTGGCCGAAAGTTTTTTACAGCAAAGGATGTCAGGCGGCATCAGGTGGTACATACTGGCAGACGTGATTTTCTTTGTCCTTACTGCCCTCAGAAGTTTGGACGGAAAGATCATCTGGTGAGGCATGTTAAAAATGCTCATCCAGATGAGTCCTGGAGATCTGCTGCTGTAGGGACATCAAGTGAGCCACCTCCAGAGGCCTCTGCATTTGAGGAAACATATACTGACTACTCATTAGAGGGAACTGAATTTAATATATGGAGTCCATCTTCACCTACAGAGGGTACATCCGAAGGCGGTCCAACTAGAGTGCCGTCTACTGACATAATAGTAGAAATTTCACCAGAACTTGATATTAAAGCAGAGCCTATAGATATTAAACTTGAGGAGACCATAATACCAGAAATAAAAATAGAGGAGCCAGAGTCCCCAAGTTGCTCATTGCTACCTATGGAGTATCCGATGATGTATATGGTGGCTCCACCATACTCTCAGACACCACCTGACTTGCCTTACATGACCACTGAGGAGCTGTCTGACCCAATAGAGGCACATTTACTCCATCAAGCGAATGTAGAATCTCTGTTGATGGATCCAGGTGAAGGGCCCTCTGGTTTGTCAAGTCAAATGCTAGAGCTGCTGGAGGAAAGTGAATCGACTTTTACAAGTGAGGAAGGCCGATCCCAGCAACGGCTACCTGCGTTTACACAGGCATTTCAAACAGCACAGAGCCCAAAACCTCCACCTCCGCCTCCCCCACCACACTAG
- Protein Sequence
- MASPPPNPKEGEEGDPEYQEESSGERPPTPPKKLIAPPASQLDSKLQYVTLGAPGPSGIKQLFRTVKVARRVPTLPRRPREGEGGSGGASTSAPPVPASRTRRDHAKRHVCETCEKRFSSPGKLSQHVLSHTGELPFSCDLCDKRFNSKFKLVRHNLIHSESRAFACAVCGKTFNRKDHLTNHVRVHNPVKKLFTCDKPDCRKSYTSHLSYRKHAALHSAEEGDLQCKICDMTFATRQEIVYHLKVHTGSRTVKNDSDKKFTCNYCGRKFFTAKDVRRHQVVHTGRRDFLCPYCPQKFGRKDHLVRHVKNAHPDESWRSAAVGTSSEPPPEASAFEETYTDYSLEGTEFNIWSPSSPTEGTSEGGPTRVPSTDIIVEISPELDIKAEPIDIKLEETIIPEIKIEEPESPSCSLLPMEYPMMYMVAPPYSQTPPDLPYMTTEELSDPIEAHLLHQANVESLLMDPGEGPSGLSSQMLELLEESESTFTSEEGRSQQRLPAFTQAFQTAQSPKPPPPPPPPH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01333127;
- 90% Identity
- iTF_00636834;
- 80% Identity
- -