Tsen016593.1
Basic Information
- Insect
- Thumatha senex
- Gene Symbol
- Zfa
- Assembly
- GCA_948477245.1
- Location
- OX419750.1:13384571-13393561[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.078 7.8 8.1 7.1 1 23 214 237 214 237 0.95 2 18 2.4e-05 0.0024 19.2 1.0 1 23 246 269 246 269 0.97 3 18 0.027 2.7 9.6 0.7 2 23 282 304 282 304 0.97 4 18 0.00086 0.087 14.3 0.8 1 23 313 336 313 336 0.96 5 18 0.00072 0.072 14.5 3.5 1 23 348 371 348 371 0.97 6 18 0.00033 0.033 15.6 0.6 2 23 402 424 401 424 0.97 7 18 0.0014 0.14 13.6 1.2 2 23 434 456 433 456 0.96 8 18 0.2 20 6.8 1.6 3 20 462 479 460 481 0.90 9 18 0.0014 0.14 13.6 0.3 2 21 486 505 485 508 0.95 10 18 0.011 1.1 10.8 2.2 3 23 518 539 517 539 0.96 11 18 0.00072 0.072 14.5 2.6 1 23 544 567 544 567 0.93 12 18 0.004 0.4 12.2 3.8 2 23 579 601 578 601 0.96 13 18 0.023 2.3 9.8 1.6 1 23 626 649 626 649 0.95 14 18 0.61 62 5.3 0.1 2 23 653 674 652 674 0.89 15 18 0.0021 0.21 13.0 2.4 2 23 680 701 679 701 0.97 16 18 5.2 5.2e+02 2.4 0.8 1 23 738 760 738 760 0.84 17 18 0.021 2.1 9.9 0.1 1 23 767 789 767 789 0.97 18 18 0.15 15 7.3 1.6 1 23 795 818 795 818 0.97
Sequence Information
- Coding Sequence
- ATGGGTACACTACCTTGCTGCTTGCTGCGAGATGCTGAGGTGGAGGCTGCCGGGGGCGTCCCCGGACCCGAATTCCCGGCTTCCTTGCACGAAAACACCACTTATCCATGGAAAATACAATTATTGCGATACTTGGTGCGGGACTACTGCGAAAGTAAGGAGTACCTAGCCATGGCGGAAACCGATGTAAAAGTTGAAATTAAAATTGAAAGGAAAGATCCTACTACATTTTTGCCTGAAGAGCCAATGTCTTATGAAATCAAAAAGAAGAAGAAGAAAAAGAAAAAGAAGCTTCTAGAAGACCCTTTTAAAGATGTTGATGATAAAACCAGCGCTGGTCGCACACCAGTGACTATAGATTTATCACCCACTGCGTTAGACCCAGAGGTTAACATAAAAGTTGAAAACATTGAAGTTGAATTAGACTTCCATGACTTTACCGATAATTCAGGTATGCTCCTAGAAGGGCCACACAGTGAAGACAGTCAGGAGCCAGCGGTGAAAATCGAGCATCACAATCATGAAGCTACCTTGCTTACCTTTGAGAGTATCATCAGGGAAAGTACTTTATTTCAATCATTGGAAGAAGATGAAGATGAAGAAGTTGCTGTCAGTCTTCCCGTGACGCCTAAACCAGATCACTTCTGTAAAGTGTGTCATCTGGTATTCCAGTCAACGAAAACATTAAAAATGCATCAAAAACGATTTCATAAAATGTTTAGGAAATCGTTCAAACATGTTTGCGACTACTGTGGTATGTCTTATGAGACTAAAAATAGTCTAGTGGCACATATTAAAAGGAAACACGGACCAAATTCTTTGCCTGTTGATAAAGAGGAGAGGACTTGTGAAAAATGTGCGTTAGTGTTTAAAGGTATGGCTAGACTACGTTTGCATATGAGACGGAAGCACGGCGAATTTCAGGACTCTTTCAAGCATGTATGTGAGGACTGTGGCCTGACTTATGACAAATACAGAAGCTTGGTTATACACATACAACGAAAGCATACAAATGAGGTACGACCAGAGATAAGCCAATGGTACAAGTGCAGGTTTTGTCCAAAAGTATTCAATAAAAGGGAAACTTACTCAAGACATGTGCAAAGAAAGCATAGAATTGCAGATGATAAAAATGAAACTAGTCGTTCGGAAAACCCCGAGGTAAATTTGGAAAATTGTAAAAATGAACAAACTGGAGAAATTACTTGTAAAGAATGTGCACTAGTCTTTTCGTCTATCACTTACTTAAAATTGCACATGCGACGAAAGCATAACGCTTTGAAAGAAGACTTTAAACTAAAATGTAGAATATGCAACTTGTCTTATGACAAGGTAGAAAGTCTCAAGCGCCATGTGAGGCGAAAGCATGATAAAGGCTCGCATTGCGACGTGTGCAATAAACAATTTGGTACTCGAGAAATGTATTTAAATCACTCACACACCAAAAGTGTACAAGAATGTTCACTCTGTGGGTTAATCTTTGCTTCAGCGGGGGGTTTAGCAAAACATATGAGGTGTACACACAAAATGGATTCACCCAACACAGTATTCTGCAATATATGCAATAAAGGATTTCATGATAAACGTTATTTGAAACCGCATTTAATGAAAGTGCATTTGCAAGCTTCATACAATTGTGCGTACTGTAAGAAAGTTTTTAAAGCTAAGGAGAGTTATCGGCGCCATCTTCTGTTCAAGCATCCCACTGCAAATCAAGTTAATACGCAGGAACAGAAATGTGATCAGTGTTCAGAAACGTTTAAGGATGAATTTGGGCTTTGTAAACATATACATTCAGTGCACAGGCATCTTTCAGATGATGGTATCACAAATGTGATTGAAGTGAAGAAAGAAGAGGATGACGTTAAAAACAAGTATCAGTGCACAAAATGCCCAGAAGGATATTTAACCTGGGAACAGTTGAAATTACATTACTTACAATGTCATAATACAACTCAGTGTCAGATATGTGGAGAGATCTTGCCTGGCAACGATTTAAAAAAGCACATACGTGATGTTCATCAAAATTCTGATATGCAATGTAAATATTGCGAGTTCAAAACAAATTTGAAATCAAGTTTAACTCAGCATATGCTGAGACATAAGAATGCTACAACAATACATTGTAGCTACCAAGGTTGTCGATACAAAACATTTTATGAAGGTGCCATGGAGAAACATAGTCAAAGGCATTTGGATCAAGGGGTCAAATTCCAATGTACTCAATGTCCATTTCAAACTATGAATAAGTACATTTTAAGGTACCATGAGGAAGCTCATGAAACTGGTAAGAAACGGTATATGTGTGACCAGTGTGATTATGCCACGATACTGCCAGCAAATTTGGTGCAACATAAGTACAAGCATTCTACTGAGAAACGTTTCAAATGTGAAGTATGCCCTTTTGCTTCGAAGTACAATACCTCACTAAGGTTCCATGTGAAAACAAAACACTGTGATCTCCCCATATCCAGCTAG
- Protein Sequence
- MGTLPCCLLRDAEVEAAGGVPGPEFPASLHENTTYPWKIQLLRYLVRDYCESKEYLAMAETDVKVEIKIERKDPTTFLPEEPMSYEIKKKKKKKKKKLLEDPFKDVDDKTSAGRTPVTIDLSPTALDPEVNIKVENIEVELDFHDFTDNSGMLLEGPHSEDSQEPAVKIEHHNHEATLLTFESIIRESTLFQSLEEDEDEEVAVSLPVTPKPDHFCKVCHLVFQSTKTLKMHQKRFHKMFRKSFKHVCDYCGMSYETKNSLVAHIKRKHGPNSLPVDKEERTCEKCALVFKGMARLRLHMRRKHGEFQDSFKHVCEDCGLTYDKYRSLVIHIQRKHTNEVRPEISQWYKCRFCPKVFNKRETYSRHVQRKHRIADDKNETSRSENPEVNLENCKNEQTGEITCKECALVFSSITYLKLHMRRKHNALKEDFKLKCRICNLSYDKVESLKRHVRRKHDKGSHCDVCNKQFGTREMYLNHSHTKSVQECSLCGLIFASAGGLAKHMRCTHKMDSPNTVFCNICNKGFHDKRYLKPHLMKVHLQASYNCAYCKKVFKAKESYRRHLLFKHPTANQVNTQEQKCDQCSETFKDEFGLCKHIHSVHRHLSDDGITNVIEVKKEEDDVKNKYQCTKCPEGYLTWEQLKLHYLQCHNTTQCQICGEILPGNDLKKHIRDVHQNSDMQCKYCEFKTNLKSSLTQHMLRHKNATTIHCSYQGCRYKTFYEGAMEKHSQRHLDQGVKFQCTQCPFQTMNKYILRYHEEAHETGKKRYMCDQCDYATILPANLVQHKYKHSTEKRFKCEVCPFASKYNTSLRFHVKTKHCDLPISS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -