Basic Information

Insect: Thumatha senex
Gene Symbol: -
Assembly: GCA_948477245.1
Location: OX419737.1:4642854-4647481[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 3.4e-06 0.00035 21.8 1.7 1 23 224 246 224 246 0.98

2 9 3.3e-08 3.3e-06 28.2 1.6 3 23 254 274 252 274 0.98

3 9 0.00011 0.011 17.1 0.3 1 23 280 302 280 302 0.98

4 9 1.2e-05 0.0012 20.1 1.7 1 23 308 330 308 330 0.99

5 9 2.5e-05 0.0025 19.1 1.7 2 23 492 513 491 513 0.96

6 9 3.2e-09 3.2e-07 31.4 1.6 1 23 519 541 519 541 0.98

7 9 0.0027 0.27 12.7 0.6 3 23 549 569 547 569 0.97

8 9 6.9e-05 0.007 17.7 1.5 1 23 575 597 575 597 0.99

9 9 0.021 2.2 9.9 0.8 1 23 603 627 603 627 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	3.4e-06	0.00035	21.8	1.7	1	23	224	246	224	246	0.98
2	9	3.3e-08	3.3e-06	28.2	1.6	3	23	254	274	252	274	0.98
3	9	0.00011	0.011	17.1	0.3	1	23	280	302	280	302	0.98
4	9	1.2e-05	0.0012	20.1	1.7	1	23	308	330	308	330	0.99
5	9	2.5e-05	0.0025	19.1	1.7	2	23	492	513	491	513	0.96
6	9	3.2e-09	3.2e-07	31.4	1.6	1	23	519	541	519	541	0.98
7	9	0.0027	0.27	12.7	0.6	3	23	549	569	547	569	0.97
8	9	6.9e-05	0.007	17.7	1.5	1	23	575	597	575	597	0.99
9	9	0.021	2.2	9.9	0.8	1	23	603	627	603	627	0.95

Sequence Information

Coding Sequence: ATGGAGGGCTGGTGTTCACTTTGGGATCTCACATTGGTAGATATTGTATACACGACCACACCGTACGTCCTCTACAAAGATGGTGTGGAGCGCGCACCGCCCGGCACGCAATGGGGCGGCGGTATGCTGGACGGCGGCTACCAGCCCATGCAGCACCAGAGCCCCGGGGGCCCCTCGCCGCAGCCCGAGCCGCAGCTCGCCTCCCCGGCGCCGTCGCCCTACCCGCCCGCGCCCCCGCCGCCCGACCCCACCGGGGCGGCAGAGGACGCGGCCCAGCAGCTCGCACAGCAACAGGCCCAGCAGCAAGCGCAGCAACAGCAGCAACAACAGCAGCAGCAGCAGCAGACCTCGCCCGAACATATGCAAGTTGAGCAACAGCTCCAAAGTCAGCCTCCAACGCAGGATCACCTGGACCGAACACCGTGCTTTGTCCCGCAGCCGGATCTTCAGCAACAGTATACGCCGTACTTCAAGGAAGCGAGACCGGCGAGCCACATGCTCAGTACTGGTGGTTTCCCCCTACACTACCTAAAACAAAACGGCGGAGTGCTCTCCCTCGAGGGTCCCCTCGATCAGTATGCGACGCCGGACTTGCGTCATTTGCCAGATATAGTGCAGGCCGAGCCGCCGAAGCCACGGAAACACAACCCGAATTCTGAGCTGCGGCTGTTCAAgtgcctcacctgtggcaaagacttcaagcagaagtctaccctgttgcagcacgagcggatacatacggactcgcggccgtacgggtgccccgagtgcggcaaacggttccggcagcagtcgcacctgacccagcacctgcgcatccacgccaacgagaagccgtacgcctgcgtgtactgcccgcggtccttccgccagcgggccatcctcaaccagcacctgcgaatccattccggtgagaagccatatacgtgcggcgagtgcggcaaacatttccgccagaaggccatcctgaaccagcacgtccgcacacaccaaggcgagCGCTATTCACACATATATGTCCCGCCCCGGCCCGCGCGCGCGCCGCCCGCACTGACCGCGCCCGCGCCGGTCACTGCCGCCGGCGCCCGTGCTCCCCGCCGCTCCCCGCACCGTCGATTCGGTCTCGCATCCATTGGCCATCCTATCAGACAAATTCTCGGTCCCCTCATCGCCCACGTATCGCCGCATCTCATCTTCAAGAACGGGACGACACCGACGCTCTGGCCCCAGGATGTGCCCTTTCCGGCCGACGAAAATAAGGAAGAGGTGCAGTCGACGTTCGGCGACGCGGACGGTCAAAACGATCAGCGCGGCTCCTGCTTCTCCCCCGGTGATACCGCACAGTATCCTGCTTATTTCAAGGATACTAAAGGTCTCAACCACTCAGTATTTACCTCAGGACTGTCACTACAATATTTAAAAGGTGGCAAACTTCCCGACGTGCTCGGCGGTCGAGCCATGCCCCTGTACGTTCGCTGcccgatctgtcagaaagaatttaagcaaaagtcaacgcttctccaacatggatgcattcatatagaatcgcgaccgtatccctgtccggaatgcggcaagcgcttccgacaacaatctcatctcacacaacaccttcgcattcacaccaacgagaagccttacggctgcgtttactgtccccgcttcttccgccaacggacgattctcaaccagcatctccgcatacacaccggggagaagccgtacaagtgcacgcaatgcggcaaggacttcagacagaaggctatcctcgaccagcacacaaggacgcaccagggcgaccggccgttctgctgcccgatgccgaactgtcgacgacggttcgccaccgagcccgaagtgaagaagcacatcgacaaccacatgaacccgcacgcggctaaggCCCGGCGGGCGGACGCCGCCAAGACGCCGCGGCCGCTGCCGCCCGCGGCCGCCGTGGTGAAGCCGGAGCTGTACTTCCCGCAGTGCTACGCGCCGCCCTTCCAGCAGTTCGCGGGCGCGCAGCCCGAGTTCAAGCCGGCCGTGGGCCCCGGCGCGTGCCTGCCGGCGCAGTGA
Protein Sequence: MEGWCSLWDLTLVDIVYTTTPYVLYKDGVERAPPGTQWGGGMLDGGYQPMQHQSPGGPSPQPEPQLASPAPSPYPPAPPPPDPTGAAEDAAQQLAQQQAQQQAQQQQQQQQQQQQTSPEHMQVEQQLQSQPPTQDHLDRTPCFVPQPDLQQQYTPYFKEARPASHMLSTGGFPLHYLKQNGGVLSLEGPLDQYATPDLRHLPDIVQAEPPKPRKHNPNSELRLFKCLTCGKDFKQKSTLLQHERIHTDSRPYGCPECGKRFRQQSHLTQHLRIHANEKPYACVYCPRSFRQRAILNQHLRIHSGEKPYTCGECGKHFRQKAILNQHVRTHQGERYSHIYVPPRPARAPPALTAPAPVTAAGARAPRRSPHRRFGLASIGHPIRQILGPLIAHVSPHLIFKNGTTPTLWPQDVPFPADENKEEVQSTFGDADGQNDQRGSCFSPGDTAQYPAYFKDTKGLNHSVFTSGLSLQYLKGGKLPDVLGGRAMPLYVRCPICQKEFKQKSTLLQHGCIHIESRPYPCPECGKRFRQQSHLTQHLRIHTNEKPYGCVYCPRFFRQRTILNQHLRIHTGEKPYKCTQCGKDFRQKAILDQHTRTHQGDRPFCCPMPNCRRRFATEPEVKKHIDNHMNPHAAKARRADAAKTPRPLPPAAAVVKPELYFPQCYAPPFQQFAGAQPEFKPAVGPGACLPAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00772240;
90% Identity: iTF_00909085;
80% Identity: -