Tsen027336.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Thumatha senex
Gene Symbol
-
Assembly
GCA_948477245.1
Location
OX419751.1:9526010-9554049[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.5e-05 0.0015 19.8 5.6 1 23 152 174 152 174 0.98
2 16 2.4e-05 0.0024 19.2 1.4 1 23 180 202 180 202 0.98
3 16 0.00043 0.043 15.2 0.5 1 23 208 231 208 231 0.96
4 16 0.004 0.4 12.2 0.2 1 23 236 258 236 258 0.97
5 16 3.6e-05 0.0036 18.6 0.4 1 23 264 287 264 287 0.96
6 16 1.6e-06 0.00016 22.9 3.5 1 23 305 327 305 327 0.98
7 16 7.4e-07 7.5e-05 23.9 0.1 1 23 333 356 333 356 0.98
8 16 1.1e-05 0.0011 20.2 2.8 1 23 362 384 362 384 0.99
9 16 6.6e-06 0.00066 20.9 1.7 2 23 505 526 504 526 0.97
10 16 3.3e-05 0.0033 18.7 2.4 1 23 532 554 532 554 0.98
11 16 0.00011 0.011 17.0 1.5 1 23 560 582 560 582 0.98
12 16 0.0012 0.13 13.8 0.1 1 23 588 610 588 610 0.98
13 16 7.1e-05 0.0072 17.7 2.0 1 23 616 639 616 639 0.95
14 16 3.4e-05 0.0034 18.7 3.5 1 23 654 676 654 676 0.98
15 16 2e-06 0.00021 22.5 0.4 1 23 682 705 682 705 0.98
16 16 6e-06 0.0006 21.1 1.8 1 23 711 733 711 733 0.99

Sequence Information

Coding Sequence
ATGTCTGAGAACATGGCTTTGGAAGATATTGGCATGTTCCTACAAGTGGAAGTGAAGGAAGTAGATGAGGAAGGAGAATACAAAAAGGAGATTGAAGAAAACGATAAAACAGAGACTTGTGAGTCATATTATGACCCCCTAAGACCTATAAAGACTGAAGTCATTGAAATAGATGTAGATGATGAGAGAGTCGTGAAACAAGAACTTATAGAGATAGAATTAGCACCCGTTCACTCATCCTTTGATGAATCTCAAAACATGACTGAAATGACTGAAGCTAATGACGAACCGCGTGGGACGAGACTTAGACGATCCGCGCGCAAGAAGCCTGAACCCAAATTAGAATTTAAAAGCGAAGAGGAGATATACGATTTTAAAAAGAAAAAAAGATCTCGTGTCATATCTAAGTCAAGTCTTGTCAAGACAAAAACAAAACGTAAATATCTTAAAAAACATGTGTGTGAACATTGTTTGAAAGTTTTTAAAACTACTAGTCATTTAAAAATACATATACGTGTACACACGGGTGAGAAGCCGTATCAATGCGACGTGTGTCAAAGAAAATTTTCAGAGAGGGCTAGCCTGACCAACCACAAGCGGTTACACACAGGCGAGAAACCATTCAAGTGTAATTTGTGCGAGAAAAGTTTTCCTATAAATAAGTCTTTAGTGTATCATATCAAAGCAAACCACGCGGAAAAGTCTTTCGAATGTGATGTGTGCGGTAAAATTTTTCCAATAGAAAAGGTATTTGAAGAGCATAAACGTAAACACACCGGGGAAAGGCCTTATCCATGTGATGTATGCAATAAACGTTTTATAGTAAAGCGTACTTTGAAAACCCATATTGATCGTGTGCATAACGAACGTAACAATATAAAAGCTATTCGCAGTAACAATCTTGAGAAAACACATAAATGCCACATTTGTGACAAGAGATTTTATTCTAATAGCGGTTTAGTTGTCCATATTCGGTCGCATACCGGTGAAAAACCTTTTAAGTGTAATGTATGTGAAAAAGGTTTTACAGTGAGGGGTAATTTAAACGCTCACATTCGGATTATTCATTCGGGAGTGAAACCTTTTCAATGTAATATTTGTAAAAAATACTTTGGCTTTAAGACTACTTTGAAAGTTCATATTCGCACACATGACAATGAGAAGCGAAAGAAAGATATTAGTCGCAATTTAAACATGGCGGAAAACACATCGGTTGCCACTCGTAAAAAGGCCAATATACATGAGTACCCTTCGAGATTCGTGAAACAAGAATTCGTGGCAGGCGATGTACGGCCGGTTGATTTTACATTTAATAGTCAACCTACAACTATTAACGAGATTGTAGAAGCAAATAACGGTGTTCCAACTCGCAGAAGATCAAGAAGGAAGTCACAACTAAAGAAAGATCTCAAAGAAGAATTAGACAACGCCAAAGTGAAAAAAAGAACTCGAGATAAAACTGCCCCCAAAACAAAACGCATAAGAAAATATATTCACCCAAAAAAACATGTCGTCTGCGATTATTGTCAGAAAGTTTTCACTCGGGATTATCATTTAAAAATACATAAACGTGTTCATACCGGTGAAAAGCCGTACCAATGCGATCTGTGCCAGAAGAATTTTTCAGAAAAAACCAGCCTGAACAACCACAAGCGGTTACACACAGGCGAGAAACCGTACAAGTGTTCAATATGCGAAAAAACTTTCGCTATAAGTAAGTATTTAAGGTATCATTCCCGTGTACATGTCGAAGAAAAACCGTTTGAATGTGATGTGTGCGGTAGAGCATTTGCTTTACAAAGAGTATACGAAAGTCACAAACGAATACACACCGGAGTAAGGCCATACCCTTGTGAAATGTGTGAAAAGCGTTTTACTGAAAAGCGACATTTAAAAACCCACGTTGATCGCATACACAATTCCGATAAACATATTCGGAGTGATACCGTTGAGAAACCCCATAAATGTCCCATTTGTGACAAGTGTTTTCATGCTAATATTAATTTAGTGGTGCATATTCGTTCGCACACTGGTGAAAAGCCTTTTAAGTGTCATTTATGTGAAAAAGATTTCGCAGTTAAGGGCAATTTAAACGCTCACATTCGTATTATTCATACTCGTGATAAACCTTACGAATGTGATGTGTGTAAGAGATCCTTTAGTTTAAAAAGTACTTTGAAAGGTCATTATCGTACACATACGGGTCAAATGCTAAATTCCTGCTTACAACGAACGCGCCAATCGAAACATGACACCGCTTTTTCGGAACCGCAAGTAGTTCCATACTCTGGACTGGCCGCAATGATGGGCGCTTGCGACGCGAGTGTGGAACAGGCTTAA
Protein Sequence
MSENMALEDIGMFLQVEVKEVDEEGEYKKEIEENDKTETCESYYDPLRPIKTEVIEIDVDDERVVKQELIEIELAPVHSSFDESQNMTEMTEANDEPRGTRLRRSARKKPEPKLEFKSEEEIYDFKKKKRSRVISKSSLVKTKTKRKYLKKHVCEHCLKVFKTTSHLKIHIRVHTGEKPYQCDVCQRKFSERASLTNHKRLHTGEKPFKCNLCEKSFPINKSLVYHIKANHAEKSFECDVCGKIFPIEKVFEEHKRKHTGERPYPCDVCNKRFIVKRTLKTHIDRVHNERNNIKAIRSNNLEKTHKCHICDKRFYSNSGLVVHIRSHTGEKPFKCNVCEKGFTVRGNLNAHIRIIHSGVKPFQCNICKKYFGFKTTLKVHIRTHDNEKRKKDISRNLNMAENTSVATRKKANIHEYPSRFVKQEFVAGDVRPVDFTFNSQPTTINEIVEANNGVPTRRRSRRKSQLKKDLKEELDNAKVKKRTRDKTAPKTKRIRKYIHPKKHVVCDYCQKVFTRDYHLKIHKRVHTGEKPYQCDLCQKNFSEKTSLNNHKRLHTGEKPYKCSICEKTFAISKYLRYHSRVHVEEKPFECDVCGRAFALQRVYESHKRIHTGVRPYPCEMCEKRFTEKRHLKTHVDRIHNSDKHIRSDTVEKPHKCPICDKCFHANINLVVHIRSHTGEKPFKCHLCEKDFAVKGNLNAHIRIIHTRDKPYECDVCKRSFSLKSTLKGHYRTHTGQMLNSCLQRTRQSKHDTAFSEPQVVPYSGLAAMMGACDASVEQA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-