Tsen027448.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Thumatha senex
Gene Symbol
-
Assembly
GCA_948477245.1
Location
OX419751.1:11917109-11932401[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 2.6e-06 0.00026 22.2 3.3 1 23 334 356 334 356 0.96
2 16 1.8e-07 1.8e-05 25.9 4.3 1 23 389 411 389 411 0.99
3 16 5.2e-07 5.2e-05 24.4 4.1 1 23 417 439 417 439 0.99
4 16 0.0051 0.51 11.8 6.2 1 23 445 465 445 465 0.91
5 16 2.4e-06 0.00024 22.3 2.2 1 23 471 493 471 493 0.99
6 16 4.7e-07 4.7e-05 24.6 5.4 1 23 499 521 499 521 0.99
7 16 4.6e-08 4.7e-06 27.7 4.8 1 23 527 549 527 549 0.99
8 16 3.1e-05 0.0031 18.8 1.3 1 23 555 577 555 577 0.99
9 16 2.6e-08 2.6e-06 28.5 4.8 1 23 583 605 583 605 0.99
10 16 6.6e-06 0.00066 20.9 1.8 1 23 611 633 611 633 0.99
11 16 4.7e-07 4.7e-05 24.6 5.4 1 23 639 661 639 661 0.99
12 16 4.4e-07 4.5e-05 24.6 4.5 1 23 667 689 667 689 0.99
13 16 9.1e-08 9.2e-06 26.8 7.5 1 23 695 717 695 717 0.99
14 16 5.3e-05 0.0053 18.1 0.5 1 23 723 745 723 745 0.99
15 16 4.4e-07 4.5e-05 24.6 4.5 1 23 751 773 751 773 0.99
16 16 0.0004 0.04 15.3 7.9 1 23 779 801 779 801 0.99

Sequence Information

Coding Sequence
ATGGCTTCTATTTGTAGAATTTGTTTAGTGGATGATGGCGTTCAGTTACGTTTGATTGTCGACACATATCTGCAAGAGATGTACGAGTCCTTGACTTTTAAGCCGTTTGTTACAGAAGAGCAGAGACCAGTAAAGGTCTGTCTCATATGTTGTGCAAAGCTGGAGATCTGCTACCAGCTGAGGAGAAGTTGTCTCCGGAGTGAGAATCTGTTTACTCAGATTTTAAAGAGCAATGTGCAAGTCAGACTACAAAAAATAAGACCCGATGCACACTTGAACAGAGGTGATGCGGTCGAGAGGGCTCCATCTGCGTCTTACAGTGATGAAGTGAAACAAGAAGACACCGAAGTTTCTGAACACGAACCAGTAGAAGATGACTACACCCAGCAATCGGATCCGGAAGAAAATTCAAATAACTCGGTTGTCAAGAATGAACAGAGCAACGTCACATTTGTTGCTGAGCAAGATCTGTTAGAAAATGACTACATCCAGCCATCAGATCCGGAAGAGGATTCAAGTGTCTCGGTCATCAAGAATGAACAGAGCGACGCCGCATTTGTTTCTGAGCACGAACCAGTAGAAGATGACTACACCCAGCCATCAGATCCGGAAGAGAATTCAAATATCTCGGTCGTCAAGAATGAACAGAGAAACGCCACATTTGATACCCTTAAGTGTCATACATACTGTAAACCGCAGCTGGTCGCTAAAAAGCCTCGACTGATCCGGCACAAGCACCAAGAAGATGTTACTTTAGGCAAACTTAAGAGAAGTATAAAAAAGGCTATAACTAAACAACCAATGAGAAAAACTAATTCAACTATTGAAGACAGTCCAGTCCAGAGAAGCAAGATCCTTGGAACCAGTGATGAAGTACAACCAAAAATACATACAGACAGAGAAATTAATAAAACAACCGCCGATAACAGTACCATATCTGTAATTGAAATCAATAGACAACGAAAAATTAAAAATGATTTTTCCAAGAAACTAaagtcatatttatgtgacacctgtcggaaatgtttcagtacaaagagttcgttagttattcacattcgtacacacactggtgagataccttataagtgtgaagtttgtaagaaatataatgaaaagagtagttcagttaatcatatttgtacacacactagcgagaaacgttataagtgtgatatatgtaagaaatgttttactaaaaagggtaatttaagtaaacacattcgtatccacactggtgagaaaccttataagtgtgatatatgtaagaaatgttttactgaaaagggtactttaagtagacatattcgtacccacactggtgagaaaccctataagtgtaatatatgtaagaaatgttttcgtaataataacaataaacatattcgaacacacactggtgaaaaaccttataagtgtgttgaatgtaacaaatgttatagtcaaaagggttctttagatatacatattcgtacacacactggtgagttaccttataagtgtgatatatgtaagaaatgttttactgaaaagagtaaattaagtagacatattcgtacacacactggtgagaaaccttataagtgtgatgtatgtaagaaatgttttactaataagggtaatttaaggacacatattcgtacccacactggtgagaaaccttataagtgtaatatatgtaagaaatggtttcgtaatacgagtgatttagatttacatattcgtacacacaccggtgagaaaccttataagtgtgatatatgtaagaaatgttttactaataagggtaatttaaggacacatattcgtacccacactggtgagaaaccttataagtgtaatatatgtaagaaatggtttcgtaatacgagtgatttagatagacatattcgtacacacactggtgaaaaaccttataagtgtgatatatgtaagaaatgttttactgaaaagagtaaattaagtagacatattcgtacacacactggtgagaagccatataagtgtgatgtatgtaagaaatgttttactagaaagagttctttagatttacatattcgtacacacaccggtgagaaaccttataagtgtcacgtatgtaacaaatgttttagtcaaaaaagttctttaaatacacatattcgtacacacactggtgagaaaccttataagtgtgaggtatgtgaaaaaggttttattgtaaagggtcaattcaatactcatatttttacacacactggtgagaagccatataagtgtgatgtatgtaagaaatgttttactagaaagagttctttagatttacatattcgtacacacaccggtgagaaaccttataagtgtgatctatgtaagaaatgttttggtcacaagattagtttagttaaacacatttgtacacacactggtgagtag
Protein Sequence
MASICRICLVDDGVQLRLIVDTYLQEMYESLTFKPFVTEEQRPVKVCLICCAKLEICYQLRRSCLRSENLFTQILKSNVQVRLQKIRPDAHLNRGDAVERAPSASYSDEVKQEDTEVSEHEPVEDDYTQQSDPEENSNNSVVKNEQSNVTFVAEQDLLENDYIQPSDPEEDSSVSVIKNEQSDAAFVSEHEPVEDDYTQPSDPEENSNISVVKNEQRNATFDTLKCHTYCKPQLVAKKPRLIRHKHQEDVTLGKLKRSIKKAITKQPMRKTNSTIEDSPVQRSKILGTSDEVQPKIHTDREINKTTADNSTISVIEINRQRKIKNDFSKKLKSYLCDTCRKCFSTKSSLVIHIRTHTGEIPYKCEVCKKYNEKSSSVNHICTHTSEKRYKCDICKKCFTKKGNLSKHIRIHTGEKPYKCDICKKCFTEKGTLSRHIRTHTGEKPYKCNICKKCFRNNNNKHIRTHTGEKPYKCVECNKCYSQKGSLDIHIRTHTGELPYKCDICKKCFTEKSKLSRHIRTHTGEKPYKCDVCKKCFTNKGNLRTHIRTHTGEKPYKCNICKKWFRNTSDLDLHIRTHTGEKPYKCDICKKCFTNKGNLRTHIRTHTGEKPYKCNICKKWFRNTSDLDRHIRTHTGEKPYKCDICKKCFTEKSKLSRHIRTHTGEKPYKCDVCKKCFTRKSSLDLHIRTHTGEKPYKCHVCNKCFSQKSSLNTHIRTHTGEKPYKCEVCEKGFIVKGQFNTHIFTHTGEKPYKCDVCKKCFTRKSSLDLHIRTHTGEKPYKCDLCKKCFGHKISLVKHICTHTGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-