Basic Information

Gene Symbol
-
Assembly
GCA_027580255.1
Location
CM050405.1:43253502-43262811[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.18 26 6.8 1.7 2 19 321 338 320 340 0.95
2 13 0.11 16 7.5 4.4 3 23 345 365 343 365 0.92
3 13 5.3e-05 0.0078 17.9 7.0 1 23 398 420 398 420 0.99
4 13 2.6e-05 0.0039 18.9 2.5 1 23 425 447 425 447 0.98
5 13 2.7e-05 0.004 18.8 2.1 1 23 479 501 479 501 0.97
6 13 0.15 22 7.1 0.3 1 16 561 576 561 578 0.89
7 13 6.3e-05 0.0093 17.7 7.6 1 23 619 641 619 641 0.99
8 13 1.9e-05 0.0028 19.3 0.6 1 23 646 668 646 668 0.98
9 13 1.1 1.6e+02 4.3 1.7 2 20 674 692 674 694 0.87
10 13 0.00034 0.05 15.4 0.0 1 20 700 719 700 721 0.95
11 13 0.00048 0.072 14.9 0.4 5 21 772 788 771 788 0.93
12 13 0.00063 0.093 14.5 0.4 3 23 798 819 797 819 0.97
13 13 0.082 12 7.9 0.2 1 23 824 846 824 846 0.97

Sequence Information

Coding Sequence
ATGACTCATTCAAAGAATTATGCTGGACAACCAAAAATAGTGAGCTTTATTGTAATAGATGATGACATCTCTGAACTTGATATCGAATTTGAGGAAAACCCAGATTACGATGAACTGACAGAAGCATGTTTACATGATGCAAATAATTCACCAAATGTATACATGGCTTCAACATCCAATCAAAATATTGAACAACACGACGCCGAATTAATTGAAGACGAAATTTCTTACGATGAACTGACAGAAGCATGTTTACATGATGCAAATAATTCACCATATGTATACATGGCTTCAACATCCAATCAAAATATTGAACAACACGACGCCGAATTAATTGAAGACGAAATTTCGATGAACATACTTGAAATGACTCATTTAAAGAATTATGATGGACCACCAAATTTACTGAGCTTTATTGAAATAAAGGATGACATCTCTGAACCTGATATCATATTTGAGGAAGAACAAGATTACGATGAACTGACAGAAGCATTTTTAGATGATGCAAATAATTCACCAAATGTATACATGGCTTCAACATCCAATCAAAATATTGAACAAAACGATGCCGAATTAATTGAAGACGAAATTTCGATGAACATACTTGAAATGACTCATTTAAAGAATTATGATGGACCACCAAATTTACTGAGCTTTATTGAAATAAAGGATGATATCTCTGAACCTGATATCATGTTTGAGGAAGAACAAGAAAACGAACTGACAGAAGCATGTTTTGATGATGCAAATAATTCACCAAATGTGGACATGGCTTCAACATCCAACCAAAATATTGAAGAACATGCCGTCGAATTAATTGAAGCTGAAATTACTTCAACAAATAGCAATGAAGAGTACCAAGGACATGAAACATCTGACATGAGAATCGATCAAGGAAGAAGTGGGCAAAGTATAACAATCGACAAAACACCAAATTTTATAAACCGAAATCATTATTTGTCATGCAAGGTATGTGGTACATTATTTTCTCAAGTCACAGATTTCAAGAATCATTGTAATATAGCTTATGGATGTGAATTATGTCACATATCATTTTGTACTCAGAAAGAATTGGACCACCATAATTTAGGGCATGAAAAACTTGAGATACCTTCCACTTGTAATGTAGCATCTTTACGTCAAGAGTCTATTGAGGAATCCAACCAGAATGTCCTCGACAAAGAAAAATCATATACATGTGAAACTTGTAATCAATGTTTTTGTAAAAAGTCATTATTGATTCGGCATGTAAAAACTCATATGGATATCAAGTATGAATGTGAACATTGTAAAAAAGTATTTTATAAAAAATCATCCATAATAAGTCACATCAAAATTCATATTCCTAAAGCAAATAGTTGTCTTTCGTGTAATCAAGTATTTTATGACGAATTACGTTTTAAATCCCACAAATGTCTTAAACTGGACAAAATCTATAAATGTGATGATTGTGGGCAAGAATTTAATCATAATGAGGCTTTGGAACATCATACAAGTTTGCATAAAAATATTGATTCAAAAAAAGAGATACCTTCCGATCATCATGTAGCATCTTTTTATCAAGAATCTACACTGAAAAATGAAATTCATTTTTCTAAAGCAAAAAGTTGTCCTTATAATCAAGTATTTAATGACGAAGTAGCTTTGAAATCTCACAAATGTTTTGATGAGTTCTTATCATTTCAATGTCTTCTTTGCAAAAAAGAATTTAATCGAGAATCGGTTTTGAAACTATTTAGGAGTTTGTATGAAAATTTGCATTTGAAAATTAGTATACCTCCCGATATTGTAGAATCTTTAAATCAAGAATTTATAGAGGAATCTAACAAGAATGTCCTCGACAAAGAAAAATCATTTAAATGTGAAACTTGTAATCAATGTTTTTGTAAAAAGTCATTATTGATTCGGCATGTAAAAACTCATATGGATATCAAGTATGAATGTGAATATTGTGAAAAAGTATTTTATAAAAAATCAGCCATAATATATCACATGAAAATTCATTTTTCTAAAGCAAATAGTTGTCCTACTTGTAATCAAGTATTTTATGACGAATTACGTTTTAAATCCCACAAATGTCTTAAACTGGACCAAACGTATACATGTGGTGTTTGTGGACTTGAATTTATTCAAAAAGCGGCTTTGGAACGACATACGAGTTTCTGTAAAAGTATAAATTCAAAAGTTGAGATACCTTCCGATCATCATGTAGCATCTTTCTATCAAGAATCTACACTGAAACCCAACAATAGTGTTCTTGACGAAGAAAAATCATTTTTAGAAAATTTGCATGTTATTAAAAAGTATTGGCACTTTTGTGGCAAAGGGTTTTATCAAAAATCAAATTTAATCTCTCACATGAAATGTCAATTTCCCAAAACAACAGAAATTTGTTCCATTTGTTATCAAGAATTCAACTACAAATCACTTTTAGATAAACATATCAAAAGCATACATGAAATGAATTCATTTACATGTGATTCCTGTAATGAAATTATTTATTCTAAATCAAGATTAATTGATCATTTGATGGCTCATGAATATGGTATAATAGATGCAAGTTAA
Protein Sequence
MTHSKNYAGQPKIVSFIVIDDDISELDIEFEENPDYDELTEACLHDANNSPNVYMASTSNQNIEQHDAELIEDEISYDELTEACLHDANNSPYVYMASTSNQNIEQHDAELIEDEISMNILEMTHLKNYDGPPNLLSFIEIKDDISEPDIIFEEEQDYDELTEAFLDDANNSPNVYMASTSNQNIEQNDAELIEDEISMNILEMTHLKNYDGPPNLLSFIEIKDDISEPDIMFEEEQENELTEACFDDANNSPNVDMASTSNQNIEEHAVELIEAEITSTNSNEEYQGHETSDMRIDQGRSGQSITIDKTPNFINRNHYLSCKVCGTLFSQVTDFKNHCNIAYGCELCHISFCTQKELDHHNLGHEKLEIPSTCNVASLRQESIEESNQNVLDKEKSYTCETCNQCFCKKSLLIRHVKTHMDIKYECEHCKKVFYKKSSIISHIKIHIPKANSCLSCNQVFYDELRFKSHKCLKLDKIYKCDDCGQEFNHNEALEHHTSLHKNIDSKKEIPSDHHVASFYQESTLKNEIHFSKAKSCPYNQVFNDEVALKSHKCFDEFLSFQCLLCKKEFNRESVLKLFRSLYENLHLKISIPPDIVESLNQEFIEESNKNVLDKEKSFKCETCNQCFCKKSLLIRHVKTHMDIKYECEYCEKVFYKKSAIIYHMKIHFSKANSCPTCNQVFYDELRFKSHKCLKLDQTYTCGVCGLEFIQKAALERHTSFCKSINSKVEIPSDHHVASFYQESTLKPNNSVLDEEKSFLENLHVIKKYWHFCGKGFYQKSNLISHMKCQFPKTTEICSICYQEFNYKSLLDKHIKSIHEMNSFTCDSCNEIIYSKSRLIDHLMAHEYGIIDAS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01434362;
90% Identity
iTF_01434362;
80% Identity
-