Basic Information

Insect: Therioaphis trifolii
Gene Symbol: Wee1
Assembly: GCA_027580255.1
Location: CM050407.1:5551848-5564126[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 2.9e-05 0.0043 18.7 1.0 1 23 728 750 728 750 0.98

2 9 4e-08 5.9e-06 27.7 2.6 1 23 756 778 756 778 0.98

3 9 0.00028 0.042 15.6 0.5 1 23 784 806 784 806 0.98

4 9 7.7e-05 0.011 17.4 0.2 3 23 814 834 812 834 0.98

5 9 2.4e-05 0.0036 19.0 1.6 2 23 1070 1091 1069 1091 0.96

6 9 6.3e-08 9.4e-06 27.1 1.8 1 23 1097 1119 1097 1119 0.98

7 9 0.0042 0.62 11.9 1.3 1 23 1125 1147 1125 1147 0.96

8 9 0.00044 0.065 15.0 1.2 1 23 1153 1175 1153 1175 0.99

9 9 0.074 11 8.0 1.3 1 23 1181 1205 1181 1205 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	2.9e-05	0.0043	18.7	1.0	1	23	728	750	728	750	0.98
2	9	4e-08	5.9e-06	27.7	2.6	1	23	756	778	756	778	0.98
3	9	0.00028	0.042	15.6	0.5	1	23	784	806	784	806	0.98
4	9	7.7e-05	0.011	17.4	0.2	3	23	814	834	812	834	0.98
5	9	2.4e-05	0.0036	19.0	1.6	2	23	1070	1091	1069	1091	0.96
6	9	6.3e-08	9.4e-06	27.1	1.8	1	23	1097	1119	1097	1119	0.98
7	9	0.0042	0.62	11.9	1.3	1	23	1125	1147	1125	1147	0.96
8	9	0.00044	0.065	15.0	1.2	1	23	1153	1175	1153	1175	0.99
9	9	0.074	11	8.0	1.3	1	23	1181	1205	1181	1205	0.95

Sequence Information

Coding Sequence: ATGGACACCAACGGTGACAACAAGATGGAATGCGACGACGAGTCGTTTTTTGTCCAGAAAATGAGACGGCTCAGCTTCGACGGTGATAAAGCTATACCGGCAATAGTAACAACTACCAGCGTACCGTCACCGGCCGGGTCTGACATCCGTCGGTCGTTTTCACCCGAGCTCGGTGTAGACTCTTCTACTCCTTTCCTCAAACCGCGAGCCTTGCATAAGGTGCGCCTCAGGGGCCAGTCGCCGTTGAGTGACACTAGCTGTGATGCGACTCGTGCTAACAATAGGTTCCGTTTGTCGGTCAACCCGTTCACGCCAACCGGTATAGAAATATTAAAGAACAAACATCGCAAGAAATTGAGTTCCGGACTAAATGAGAGTTTCTCCAGTTCAGGTCAGTCGTCGGATCATAGTAACCATGATAGTAGCCAATCCACACCACCCGATCATAAGACGTCCTCTACGATTGATCCATCCATTAGGGATTTGATGAATGAGGGCGAAGTGACCAACGTCAGTATATATGAATTGCAGACATCACGTTTCAACGAAGAGTTCCGTATGGACGAGTTCATTGCCACCGGTACGTTTGGGGAAGTGTACAAGTGCACAAATTTATTAGATGGAATTGCATATGCCATTAAGAAAACCAAAAAGACAATTTACCATAGTCAAGAGTATTTCATTCGTAAAGAAGTATATGCTCATTCTGTTATTGGACGACATCCGAACATAGTCTCGTATTTTACAGCATGGCATGAAAAAGGTCATATTTATATTCAAACAGAATTTTGTAATGGTGGTACTCTAGAGCGCATGATTCATGATTCAGATCATGTATTCTGTGATAGTGCTTTGAGACGACTTCTTTGCCATGTGTGTAAAGGTCTTGCTTATATTCATTCCAAAAAACTAGCCCACTTAGATATTAAAGCAGCCAATATATTGATTAGTCGTACTGATGGCGCTTTGTTGTTTGCTGAAGATCTTGACGATGATGAAACAATTGACAAAGATATTGTGTATAAGATAGGAGACTTTGGACACACAATATGTGTTGAAGATGTACGAACTATAGAAGATGGAGATTGTCGATATTTACCTAAAGAGCTATTACGTGATGATTATTCTCAGTTGCAAAAAGCTGATGTGTTTTCGACAGCGCTTACTGCATATGAGGCGGCAACTAAAAAAGATTTACCTAAAAATGGACCAGAATGGCATCGTTTAAGAGATGGTGAATTTTCTTTGCCTCAAACACCTGTATTTAGTACTGGTCTTGAAAAAATGCTAAAGAAAATGGTTGACTTGAATCCTATTAATAGGCCAAATGCTTCTACAGTGGTTAATCTGTTGCTTGATAGAGGAATGGCAGCTGTAAAGCAGCAACAAGATGAAATGGAAGTATGGAAATTAAGTTCTAAGTTTCTTACACCTTGTTATTCGGTTGAGACTCAAACGCCTCAAACATCATCAAGAACTTTTGACCGAATTGGACAGAGAAGATATGAAAGCTCTAAATTTTACCGTACGAGAAAAGAACGAATTAAACGATTAGTTGGAAGTGATGAAGGGGATATTATGGCAATCAATTTCTCAGCTTCATTCGCAGCATGTCTGGCAGCAGGCCTCAAAGTTCCTCGGAATTTTATGTATTGCATTGCCCAAGAGAACGGTGCTCCATATGTTATATACAACAAAGATGGCCACCACCAACAAGGGCCAAATGGTAGCAACGGTCAATGGGGACCGGGACCTTCACAAAACGGCTACCCAGCTCTTGTATCGTCTCAACATGAATCAGCAGAACAGTCGACTGAACAGGCATCTCAATCAACGATTGCATCGCCTTTGCCATCACCATATCCTAATACCAACCATTCTATTCAAGGTTCTGGAAATGGTGCTGAAGAAGAAACGCCACCTGAAGACAGTGTTGTTGAATCGGATCGAACCCAAGGAGGCCAGTATGGTGCGGGCGACCCTTCCAATTACTATTCTGGTGTGAGAGGAGGCCCTCCACATATGCTGAGTCCATCTAGTTTCATGTCTTATCTGAAACAACCTGGGGTCATGTTAACTCCTTTAAACCCGGCTGAAGCGTCTGGTGATTTTCCTAACATGCCAGATCTTATACATCAACAACAAGAAGGATCTGGGAAAAAAGGTTCTGATCTTCGACTGTTTAAATGTCTTTCAtgtggcaaagacttcaaacaaaaggctactctaatgcaacacgaacgcatacataccgactccaggccatttgtgtgcagtgattgtggaaaaagatttcgtcaacagtcccatcttacgcaacatgtgcgtattcatgccaatgaaaaaccttttgtttgcgtatactgtgaaagaaccttcagacagcgagccatcctcaatcagcatttacggattcattcgggtgagaaaccgtacgggtgtggagactgcggcaaggcgttccggcagaaagccatcctgaaccagcacgtccgaactcaccaaggcgagcACTCTCATTCCTCGTTAAATAGTAGCGATTCCTCAAGCTCACCTCCGCCCTCTCAACTTCACAATAATTTAAACGCTTTTCTCAAGTCTTCAGCTGAAGCGTTTAGAATGAAATACTACCCGAACCTAAGCGATAGCGCACAAGACGAACAACACTTGACCAACTCTGAATTTAGAAATGTTGCTTCTAGATTGCTACAAAACAATCTTAAAGTTAAACAGTCAAATTCTTCTACCCATAATTCTTCATCTAGTAGCCCTAAAACCTCTTTCAACTTGATGGATTTACCTACACGATCTTTCCCTAAAACCATTGTTAGGACAAATATTGCCCATCTTAGAAATGAAGAAGTTCTCCCCATGAGAGTTGTAACTGAAGTTGAAAAAAATCACGCTGCACATGGAGTAAATGGTGACAACGTCCGAGGAGAAAATGTCGCTCCGCTCAAGGAAGACGTCGGCCCACACTTAGTGTATAAAAATGGACAACTTTGGCCTCAAGACGTGCCATTACCACAGTCTAAAAGTGGACAATATGATTCAAATGATCAATGTTTTTCTCCAGAAAATGCTCCTCAGTTCCCTGCATATTTTAAAGATGCCAAAGGTGTTGTTCATGAAATTTTTGGTCAAGCTGGTAAAAGTCTACCCGATGTAATCCAACATGGTCGCAGTGCTGGCATGCCACTTTACGTTCGTTGTCCTATTTGCAATAAAGAATTTAAACAGAAATCTACTTTGCTTCAGCACGGTTGTATTCATATAGAATCTAGGCCTTACCCATGTGTAGAATGTGGGAAACGATTTCGACAACAGTCACATCTTACTCAACATCTACGTATACATACAAATGAAAAACCATTTACGTGTATTTATTGTGGACGAAATTTCCGACAACGTACTATACTAAATCAACATTTACGGATTCATACTGGTGAGAAACCATATAAATGTTTACAATGTGGCAAGGATTTTAGACAAAAAGCCATTCTAGACCAACACACGAGAACTCATCAGGGAGAAAGACCATTTTGCTGCCCAATGCCCAACTGTCGTCGACGGTTTGGTACCGAACAAGAAGTCAAACGTCACATTGATAACCATATGAACCCACATGCTAATAAACGTAGATCCGATAGTGGCAAACCAGGAAGGCCACCACATTTGAATACTATACTCAATCAACCATCTGGCATTGTTAAACCAGAATTATACTTTCCTCAGTGTTATGCAATGCCTTCACCGTTTGGTAACCACCACCATTCTCAACAAAGTTTTGTGTCCTCTTCTCCTGTTAATCATGTTCCTCCACCTCCTCCACCTGAGTTCAAAGGCCCACCTACAGCAGTTAATAACACCCCAGATTTTAAGGCTCCACCTACAAATCTTACGACGGCTGCACCTATTGCAGTTGTTCAATAA
Protein Sequence: MDTNGDNKMECDDESFFVQKMRRLSFDGDKAIPAIVTTTSVPSPAGSDIRRSFSPELGVDSSTPFLKPRALHKVRLRGQSPLSDTSCDATRANNRFRLSVNPFTPTGIEILKNKHRKKLSSGLNESFSSSGQSSDHSNHDSSQSTPPDHKTSSTIDPSIRDLMNEGEVTNVSIYELQTSRFNEEFRMDEFIATGTFGEVYKCTNLLDGIAYAIKKTKKTIYHSQEYFIRKEVYAHSVIGRHPNIVSYFTAWHEKGHIYIQTEFCNGGTLERMIHDSDHVFCDSALRRLLCHVCKGLAYIHSKKLAHLDIKAANILISRTDGALLFAEDLDDDETIDKDIVYKIGDFGHTICVEDVRTIEDGDCRYLPKELLRDDYSQLQKADVFSTALTAYEAATKKDLPKNGPEWHRLRDGEFSLPQTPVFSTGLEKMLKKMVDLNPINRPNASTVVNLLLDRGMAAVKQQQDEMEVWKLSSKFLTPCYSVETQTPQTSSRTFDRIGQRRYESSKFYRTRKERIKRLVGSDEGDIMAINFSASFAACLAAGLKVPRNFMYCIAQENGAPYVIYNKDGHHQQGPNGSNGQWGPGPSQNGYPALVSSQHESAEQSTEQASQSTIASPLPSPYPNTNHSIQGSGNGAEEETPPEDSVVESDRTQGGQYGAGDPSNYYSGVRGGPPHMLSPSSFMSYLKQPGVMLTPLNPAEASGDFPNMPDLIHQQQEGSGKKGSDLRLFKCLSCGKDFKQKATLMQHERIHTDSRPFVCSDCGKRFRQQSHLTQHVRIHANEKPFVCVYCERTFRQRAILNQHLRIHSGEKPYGCGDCGKAFRQKAILNQHVRTHQGEHSHSSLNSSDSSSSPPPSQLHNNLNAFLKSSAEAFRMKYYPNLSDSAQDEQHLTNSEFRNVASRLLQNNLKVKQSNSSTHNSSSSSPKTSFNLMDLPTRSFPKTIVRTNIAHLRNEEVLPMRVVTEVEKNHAAHGVNGDNVRGENVAPLKEDVGPHLVYKNGQLWPQDVPLPQSKSGQYDSNDQCFSPENAPQFPAYFKDAKGVVHEIFGQAGKSLPDVIQHGRSAGMPLYVRCPICNKEFKQKSTLLQHGCIHIESRPYPCVECGKRFRQQSHLTQHLRIHTNEKPFTCIYCGRNFRQRTILNQHLRIHTGEKPYKCLQCGKDFRQKAILDQHTRTHQGERPFCCPMPNCRRRFGTEQEVKRHIDNHMNPHANKRRSDSGKPGRPPHLNTILNQPSGIVKPELYFPQCYAMPSPFGNHHHSQQSFVSSSPVNHVPPPPPPEFKGPPTAVNNTPDFKAPPTNLTTAAPIAVVQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00136330;
90% Identity: -
80% Identity: -