Basic Information

Insect: Thereva unica
Gene Symbol: zfh2
Assembly: GCA_949987705.1
Location: OX465286.1:16672489-16693087[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.028 8.1 9.1 0.3 1 23 132 155 132 155 0.95

2 10 0.0045 1.3 11.6 0.2 3 23 271 292 270 292 0.94

3 10 0.19 54 6.5 0.2 1 21 336 356 336 360 0.91

4 10 0.0012 0.35 13.4 2.3 1 23 406 428 406 428 0.96

5 10 0.00013 0.037 16.5 2.0 2 23 435 457 434 457 0.94

6 10 0.11 32 7.2 5.5 1 23 590 614 590 614 0.92

7 10 0.0088 2.5 10.7 0.6 1 22 635 656 635 659 0.89

8 10 0.004 1.1 11.8 0.1 1 23 736 760 736 760 0.93

9 10 0.74 2.1e+02 4.6 4.0 1 19 863 881 863 886 0.91

10 10 0.00035 0.1 15.1 0.2 2 23 1218 1240 1217 1240 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.028	8.1	9.1	0.3	1	23	132	155	132	155	0.95
2	10	0.0045	1.3	11.6	0.2	3	23	271	292	270	292	0.94
3	10	0.19	54	6.5	0.2	1	21	336	356	336	360	0.91
4	10	0.0012	0.35	13.4	2.3	1	23	406	428	406	428	0.96
5	10	0.00013	0.037	16.5	2.0	2	23	435	457	434	457	0.94
6	10	0.11	32	7.2	5.5	1	23	590	614	590	614	0.92
7	10	0.0088	2.5	10.7	0.6	1	22	635	656	635	659	0.89
8	10	0.004	1.1	11.8	0.1	1	23	736	760	736	760	0.93
9	10	0.74	2.1e+02	4.6	4.0	1	19	863	881	863	886	0.91
10	10	0.00035	0.1	15.1	0.2	2	23	1218	1240	1217	1240	0.95

Sequence Information

Coding Sequence: ATGTATAACAATGTGTTGCCCCAAAGGCAGCAGTGGAGATCAGGTTCACGCAGATATCGCGGTAGTGATCGTAGAACGCGATGCCTAGTTGAGATCGAATTGTATGTGCAAGCGGCAAGTTTCAACACAATAAAAAGTGAAAGAGCTAGCCCAGAACAGTCACcaattgaaaaatatgataCATCAATTGATAATATCAGTAATCAAGATATGAAATCATTGCATCATAcatcaacaacaccaacaagACCGGTATCGCGTGATAGTCGCGGTGAAAATTTATCAGCAAATAACAGTGGCAATAGTAGCAGCGGTAATGGCAATTTGCATTCACCAACAttacagcaacaacagcagcaatcgctacatcatcatCAGCCACCATCAACAATATATAAATGTAACAATTGTGATTATTTTGCtgaaactaaaaatgatatggAACAACATATTGATAATGCGCATCCAAATTATTCGGAACATGATTATTTAACAATACCAACCAATCCCGCAGCATTGCAGGCATTTCaagctgctgttgctgctgctgctgccgctgcagctgcagcagcatcATCATCAAGTACAAAATCAACAATTGAATTACCGCAATCACCAATATCTGGTGGTGGTGTAGCTGGTGGTATGATTGGTGATAATCAAAATGTTAGCAGTAGTAGCAATTATGATGAGATCAAGTCTGAACGTATTGATGCTGATGAATCAGAATCTGGCGGTGATATTATGGATCAGGATCAGCCAGATATTGATAATATTGACTCAAATAATGATGATACAATCAGTATACTATGTCCATTGTGCCAAGATAGCTTCACTGATAAAAAATCATTAGAGAAGCATGTTATGGGTGTTCATAGTGTTAATAGTGATGGTCTAACACGTTTACTACATTTAGTTGATACTAGTCATTGGCTAAatagtaatattaaaaaaagtcccGATCATAATAACAGTTCTGAACAAAATTTATCTATTAATTGTGATTATGAATGCTTAAAATGTGGGCAAAATTTAAAATCGTATCAGGATCTACTAATACATGCCAATGATAATCAGCATTATCAAACAATAAACGAACAATATCAATGCTTAATTAAGCAATGTtcacaattgtttattaatttgcCAGCTATGTTAACGCATTTTAAGGATACCCATATGAATATTGTCATATCAGAACGACATGTATATAAATATCGTTGTAAACAATGTTCATTAGCATTTAAAACACAAGAGAAACTCAATACGCATTCGTTATATCATACAATGCGCGATGCAACCAAATGCATGATATGCAATCGCAGCTTTCGTAGTACACAATCGCTACAGAAGCATATGGAGCAGTCACATCAACACcaccagcaacagcaacaacaacagcattcACATCATCAAAGTGTTGGTGGAAATAGTCCATCACCATCACCGAATAGCACTGGCTGCAATGATCATATTAtcaatgataataataaaaactcaacaataacaacaactaATGCATCATCGTCAGCTATAGATGATTATATAACATCACCAACATCAAGTATTAAGCAGGAGGATAACGATTCTGTTACAACAACAGCAACCGCTCAAGATTTAGTATTACGTGATGATATACAattgcagcagcaacagcaacaggACAATATAAGTGGAATTTGCAGCGATGTTGAAACAACTGAACttgatatatatttaaattccCAACAAATGTCTGAAGATAATTACAATGATATTAACCGCAAATATAAATGTCATAAATGTAAAATGGCATTCACACATCAAATATTTATTGCTCAACATTATAAAACCAATCAGCATAGACGTAAcgagaaattaaataattatccatTGGAAAAATATTTAGACCCAAATCGGCCATTCAAGTGTGAAATATGTAGAGAAAGCTTCACACAGAAAAATATCCTATTAGTACATTATAACAGTGTATCGCATTTGcataaattgaaaaagcaaaatgaaaataataataccCCATCGACATCGCCAACAAGCAATTTATTAATTGGTACAACAGAATACGATCGTAAAAGTATCGAGCTAGATCATCGCAGCAATGATTATGACCGTAAATCAATAGATTTAGATATCGAAAATTCGGTTAATGATCAGCAAAAGCGTAAGCTAAGCCCAGAAAGCGATTATGATAGTCCGAAGAAGCGTTTTAAATGTGACATTTGTAAGGTTGCATACGCACAAGGTAGCACACTTGACATCCACATGCGTAGTGTACTACATCAAACAAGAGCATGTCGCTTACAAGAACAGCAATCGTTGCAGCAGCTCCAGCAACAGCAATCTATATCGCCAAATTTAGCGCGTATTGCCGATTTGAgccaacagcagcaacagcagcagcagcaccaacAGAGTATCAGTCCAACACCATCAAATCTAAGCGGAATACAGGATGATGCTATACCAAAATTTAACAATCAAATCTATAAAACACTGTTAGAAAATTTCGGTTTTGATATTGTTAAGCAATTTAATGAAATCAACAAGCACAGCAATGAGCTAGCACGCGAAATAAGCGAAGATAAATACTATTGCCGTCATTGTAAGAAGATATTCTCATcaatatttgttttaaaatcgCATTGTGAAGAGATTCATAATGATAAAATACCGCTTGAGTTCCTAGagaaatttgctgaaaaatttaaaaattattaccttGAAGCTAGCGAAAACGACAATGAAATACTTGACTTTTCAAAGAAGCAACCATCAGAGCCACCATCGCCAGCGCCATCATCAATTGGTGGTGGTGGAAGTGGAGGTGGGCATAATAACAACAATGTCAAGGAGGAGAAACTTGATAACGTTCAACCGATTGTAGTAAGTTCGCAGCAAAATATTGCTAATTCGCCAACTCCACCATCGCCGCCACCGCAATTGCCACAAATAACATCCCAACAACAGCTTCAgctgcagcagcaacaacaacagcagcagcagcagcaaccacCACAAATTCCGCCATCAGCTGCATCTGTAGCTTCAGCATTACTcaaacagcagcagcaacaacaacagctagCATCTCCACAAAATCCATTAATGCCAGATTTGGCACAAAAACTAAATATCGATCCAACAATATTGGCGCAAAAAATTATGGAACAAAATTTAGCAAATTTACCACCAAATTTTGCTAATCTACCACAAAATCTACAAAGTCTACAAAATTTACAAAGCTTACAAAGTTTACAAAGCttacaaaatttaccaaacaTGGGCAATATACCGTTAAACACATTGGACATGTTGAATTTAATGCAATTCCATCATTTAATGTCGTTAAACTTTATGAATTTGGCACCACCATTAATATTTGGTGCAACTGGAGCTGCTGCTGCCGCGGCTGTTGCCGGTAGTGTACCACCAGTAACACCGGAACTGCCAGTACCAGGACAACCAGTACAATTATTGCAGCAACAAGCAGCTGCTGCCGCTCAGAATGAATCAAATCCGAGCAGAAAAATGCTGgaagaaatatcaaaaaaagttaatttaaaaaaacgcgTCGTACAGGTTTGGTATCAAAATTCTCGTGCCCGTGAAAGAAAAGGACAATTTCGGCAAAATTtacaaataattaataaaaaatgcccATATTGTGGtgccatatttaaaataaaatcagccCTCGAATCGCATTTACAAGCAAAACATCCAGATAAACAACCAATTAATATTGATCAAATACCAGATGTTAAACCAATGGACGGCGGACTCTCATCATTTAatcaaaataatataacatcAAGCATTGACCAATCTGGCGGCGGAAATAATTGTACAACATCGGGTGGCAGCATATCAAATCTAGTTGGTGCAGGTGGctttagtaataataataataatggcaGCAATTTACTACATAATAGTGATGGATTATTAAATGATCATAAACAGAATGGTAATAATGATAATCTaacatcatcatcaacaacagcaacaatacCAACAGCATCTTTAATGGATTCAGCTGGTAATTTACAAAATCTTAATAATACATTGTCAAAAGGTGGACTACCATTGGACTTAAGTAAAAATCCTCTTAAATATGAGCCAAGTGAAAGTGAAATTAGTTATTCAGACTCTAATAATGATCATGAGGAATCGAatgattattttataacaacATCATCCAGTGgcaatataattaataataataatcatagtAAAAATGATAATAATTTGACAACAACATTCGGTggacatcatcatcatcataataataatagtaataaccATCAAAATAATAACAACGATTTATATTATGATAGTGATTTAATGCATAGTGGCAATAGTATTGGTATTGGCAAAATATCATCTAGTGATGCAGCTATGATGTATTCAAATGACCGGGATAATGCTATATCACCAGCTAGTCCAGCATCTAGTACTCAGAGTATGCAGAAGAAGCGTTTTCGTACACAAATGAGTAATATACAAGTTAGAATTTTACGTATGCTATTCCAAGATGTTAAAACACCAAGCATGACTGACTGTGAGAACATTGGTAAAGAGATTGGACTACCAAAGAGAGTTGTTCAgGTCTGGTTCCAAAATGCACGTGCCAAAGAAAAGAAAAGCCGCAACAATCGTTTCATTGATGAAGCATTGGATAATACTGAACAATCACCAGATATAATACCATTACCAGAAGATTGTAAATTATGCAATATACAAAAGGTTAATGTACAGGAGCATGTTTTTTCTGCTGGTCATATTGCAAAAGTTAAATCAATGCTAGAATCAACTGATTTTTCAAGTGGTGGTAATGGTAATGATATATGCGATCAGAATGatcaacaacagcagcaaataAAATGTTCACAATCACCAACATTAAATAATATACCACATCATAATTCAAGCAATGATCATGATTCAATAAATATTTATAGCCAAATACATTCAATGTTTATGAATCATACTGGTGGTAATAATAATTgtgttggtggtggtggtggtggtggtggtagtgGTGCGAAAATGATTGATGATCTATGTTCACCATCTGATCAAGCTtgtaatgataataataatccaATGCAGCATCATAGCATATCACAGCATGATGGTGGTAATACTGTAGCTGCAACAGCAGCAGCCATGATTAATTTACAACATCATTTGGCAGctgtacaacaacaacaacaacaacaacagcaacaacaacatcaacgaGAGAACTCATCAACACCAGATGGTGGTAGTTCGGcggccgctgctgctgctgttgccgCACATCAAATATTAATGGAGAATAATTTATTGCTACAAATAAATGCTGATAATAGTATGCAAACTAACACCAATTCAGAAATTCTGCAACAATTATACAACTACAGCCACATGAGCGGTGAGTTGATTAAGtaa
Protein Sequence: MYNNVLPQRQQWRSGSRRYRGSDRRTRCLVEIELYVQAASFNTIKSERASPEQSPIEKYDTSIDNISNQDMKSLHHTSTTPTRPVSRDSRGENLSANNSGNSSSGNGNLHSPTLQQQQQQSLHHHQPPSTIYKCNNCDYFAETKNDMEQHIDNAHPNYSEHDYLTIPTNPAALQAFQAAVAAAAAAAAAAASSSSTKSTIELPQSPISGGGVAGGMIGDNQNVSSSSNYDEIKSERIDADESESGGDIMDQDQPDIDNIDSNNDDTISILCPLCQDSFTDKKSLEKHVMGVHSVNSDGLTRLLHLVDTSHWLNSNIKKSPDHNNSSEQNLSINCDYECLKCGQNLKSYQDLLIHANDNQHYQTINEQYQCLIKQCSQLFINLPAMLTHFKDTHMNIVISERHVYKYRCKQCSLAFKTQEKLNTHSLYHTMRDATKCMICNRSFRSTQSLQKHMEQSHQHHQQQQQQQHSHHQSVGGNSPSPSPNSTGCNDHIINDNNKNSTITTTNASSSAIDDYITSPTSSIKQEDNDSVTTTATAQDLVLRDDIQLQQQQQQDNISGICSDVETTELDIYLNSQQMSEDNYNDINRKYKCHKCKMAFTHQIFIAQHYKTNQHRRNEKLNNYPLEKYLDPNRPFKCEICRESFTQKNILLVHYNSVSHLHKLKKQNENNNTPSTSPTSNLLIGTTEYDRKSIELDHRSNDYDRKSIDLDIENSVNDQQKRKLSPESDYDSPKKRFKCDICKVAYAQGSTLDIHMRSVLHQTRACRLQEQQSLQQLQQQQSISPNLARIADLSQQQQQQQQHQQSISPTPSNLSGIQDDAIPKFNNQIYKTLLENFGFDIVKQFNEINKHSNELAREISEDKYYCRHCKKIFSSIFVLKSHCEEIHNDKIPLEFLEKFAEKFKNYYLEASENDNEILDFSKKQPSEPPSPAPSSIGGGGSGGGHNNNNVKEEKLDNVQPIVVSSQQNIANSPTPPSPPPQLPQITSQQQLQLQQQQQQQQQQQPPQIPPSAASVASALLKQQQQQQQLASPQNPLMPDLAQKLNIDPTILAQKIMEQNLANLPPNFANLPQNLQSLQNLQSLQSLQSLQNLPNMGNIPLNTLDMLNLMQFHHLMSLNFMNLAPPLIFGATGAAAAAAVAGSVPPVTPELPVPGQPVQLLQQQAAAAAQNESNPSRKMLEEISKKVNLKKRVVQVWYQNSRARERKGQFRQNLQIINKKCPYCGAIFKIKSALESHLQAKHPDKQPINIDQIPDVKPMDGGLSSFNQNNITSSIDQSGGGNNCTTSGGSISNLVGAGGFSNNNNNGSNLLHNSDGLLNDHKQNGNNDNLTSSSTTATIPTASLMDSAGNLQNLNNTLSKGGLPLDLSKNPLKYEPSESEISYSDSNNDHEESNDYFITTSSSGNIINNNNHSKNDNNLTTTFGGHHHHHNNNSNNHQNNNNDLYYDSDLMHSGNSIGIGKISSSDAAMMYSNDRDNAISPASPASSTQSMQKKRFRTQMSNIQVRILRMLFQDVKTPSMTDCENIGKEIGLPKRVVQVWFQNARAKEKKSRNNRFIDEALDNTEQSPDIIPLPEDCKLCNIQKVNVQEHVFSAGHIAKVKSMLESTDFSSGGNGNDICDQNDQQQQQIKCSQSPTLNNIPHHNSSNDHDSINIYSQIHSMFMNHTGGNNNCVGGGGGGGGSGAKMIDDLCSPSDQACNDNNNPMQHHSISQHDGGNTVAATAAAMINLQHHLAAVQQQQQQQQQQQHQRENSSTPDGGSSAAAAAAVAAHQILMENNLLLQINADNSMQTNTNSEILQQLYNYSHMSGELIK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01431665;
90% Identity: iTF_01431665;
80% Identity: iTF_01431665;