Basic Information

Insect
Thereva unica
Gene Symbol
-
Assembly
GCA_949987705.1
Location
OX465283.1:160151217-160165042[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.071 20 7.8 1.2 1 23 879 902 879 902 0.93
2 13 0.81 2.3e+02 4.5 3.2 1 23 1007 1029 1007 1029 0.95
3 13 6.4e-05 0.018 17.4 2.1 2 23 1032 1053 1032 1053 0.97
4 13 0.00019 0.054 15.9 0.1 1 23 1059 1081 1059 1081 0.97
5 13 0.00014 0.039 16.4 6.5 2 23 1088 1110 1087 1110 0.95
6 13 3.6 1e+03 2.5 0.4 5 23 1122 1140 1119 1140 0.95
7 13 0.0097 2.8 10.6 3.6 3 23 1147 1168 1145 1168 0.95
8 13 0.12 36 7.1 0.1 2 23 1179 1199 1179 1199 0.95
9 13 5.1e-05 0.015 17.7 0.8 1 19 1205 1223 1205 1227 0.95
10 13 0.00021 0.061 15.8 0.3 1 23 1235 1257 1235 1257 0.98
11 13 0.00026 0.073 15.5 7.2 1 23 1263 1285 1263 1286 0.96
12 13 0.00096 0.27 13.7 5.4 1 23 1291 1313 1291 1313 0.98
13 13 0.0092 2.6 10.6 5.6 1 23 1319 1341 1319 1342 0.93

Sequence Information

Coding Sequence
ATGGGTGAGCAGGTTCCTTGCCCCGTGTGCACATTATTCCTGCACCCGGGAATGAGCCTTGCTGATCATTTGGAAACACATCCAAAGGAGCAAGTTATTAAAGCTTTGGTAAGCCTCGCTTCCGCGTTCCCATCCAATAAGGAACAAAAAATTGCATCTCCAGCACAAGAAGCACCCCCTATCATCCCTACAATACATGCAGCTGAAAGTAATACAAACATATTAAGCACTAGCGAATCGAAATTGGGATTTGTTGCTCCCAATAAGCAaaatgttatgattgttaatagaCAAAGTACTATGGTATATCAGACTAGTGATGCTGAGCATCAAAGACCGTTGTCACAAAGTATACCAGAGTTGGAAACCACTTCAGCGATGCAGatgTTCAACATGCCAaataatcaaacaaaaattcttcCTCCTCCACCTGCTTATGGAACAGCAATAAATCAATTACGATCtcaaaataataatcaaaatttttatggaCGGCAAATgcaattacaacaacaacaatatgaGGCTGAAAATTATGATTATGGTCCCCCCAGCAGTAACTATGACTATCCAAGGACAATATCACCCGCTCGCCCGCCATCAAGACCAACATCATCACCATCTGTCTTACGTTTTGCCGAAAGTCCAGTAACGGCACACTATGTGGAACGGGAGAATGGGGATTTCGTAGTACAAGAGACTCCACGGCATGTTGTCCAATGTGTCGAGAAAGATGATGGAGAATTTTCTGTGATTGAAAAAGTAATAAGATCACCACCAAGTGTTGTTCAATTTAATGATAATGAAAATaccgaaaataatgaaattaataatgaaagtaATGATAATGATGAAAATAATACTGATCAATATCATCAACCTGGTGAGCCAGATGAAGTACAATGCGATAATCATGAAGCTAGTAGTGAAACATCACAAATTATTGAGACGCAGGAGACGCAGCAGCAACAGAAGGTACAGCCATGCGTTACGGTTTTAAGCGATGTTAAGCTAGATCCGACAGAATCTTTGGATATAATGGAGAATATTATAGCTGCAAGTAAACAACGTAAAGGACGTTTAACAGATCTGGTAGAATCGGTGACTGAAGTTATTAAAAAAGAGGAATCAGAGAAAAACCTGGAGAATATATTTAGTCATCTGGAAAATGAAGATTCATATAACGAACAATTTGATGAAAGTTGTAAGACTGATGAACAAAAGAAGCCGTGGTCATCGGCAGCAACCAGTGTAATACGACTAGCTACACAGCAGCCAAACACTAGTCAAGAGCCTATTCAACAAAAAGACAACTTGAAGAAGCCTGGAATTACGCCAAAAATTAGCTTACCAATTAAAAGATCATTCAGAAAAACACCGAAAAAACTtgtagttaaatttaaaaatcggCCAAAATCTTCGAATACACGTGAAACTGTCGCGACGACTATTGGTCCTCAGCCGGGGCCGTCTGACACGAAAGAGAAATTTGTAGAAGAACCTATGATAGACCTTTCGACGAAGAAGCCTGATttgataaaacaacaaaatgaacaagaaaaaaacccACCAGAAATGGCCGAagaaaagcaatttttcgaaaagaaATTAGAAGCAATAACCAACGAgaaaccaattgaaatcgatgAGGAAGTTGATAAAAAGGACATAAAACCGGTTATAGAACCTATGATGCCTTGTGTTATCGTTCATGAGCCAACTGCAATGGATGCAATGGAAGAAGAAATGGAATCAGAAATACCAACTGAAAAAATCGAAACGATTAGCAAGGAAGAAATCAAAGATGATAAAAAAGACTCAGAACTTTCAAAATTACTAGAAGAATGCATAACTAATACAGAAACTGATTCTTATTCAGTTCATTTATCTACAATCGATACAATTCCACATGCTCCAACAGGAAATTTCATCGTTACAGATTTTTCTGAAAGCAATGCATTtgatacacaaaaaaatgaAGTAACTAATTTAACTCCAATCGCATTAACAACAACATCTACATCATCATTTTCAAAACCTTCAACCAGTTCCTTTGCATTAAGAGATCAGACTGATTTTCAAAGTTCGCATAGTTTTAATGATTATCCATTCAGTTTTTTATACGCTAATAGTATCGATAAAAATCGATTATCACCAATTTATCCAGGTGATGATCAATCATGGCATCGTTATAGTGGGCCTATATTTCAACAAAGTCAACAAGTTCATAATCATAATGATTTAGATGGTGAAAAGAATAGCTATATTGATTTAGATGCATGTAAGAAACAAATGTGCACTGATACAGTACCTTTAGATGCGTTAAATATTCGTACTGATGAAAAAATGCCAGCGAAAGGGGAAATTTCGGAACAAGAGAGTAATGGTGAAATTGATTTATCATGGAGTCAACCGTTATATCACGACACCCAAAGGTTTTCCAATCAATTGGAAAATTATGTTACTAGGGGAAGCGGCAGCTATAGCAACGATGCATTCTTTTTCTATCCTCAGGATTTAAGTACTGAAACAAAACCTATACCATCTTTATTGCCAACTCCAGAACACGAAAAGCCTCCTGAATCTCTAATAAAAAAAGAGCCTAGAAAAACAGCAACTCGCGGGAAAAAAACCTTTCAGTGCGATCATTGTCCTTCGTCATTCCCAAAGCTAAGAGAACGTAACACCCACCTTATAGAACAGCACAATTATAAGCGAATTAATAGACGTTTAGTAAGAGAACCGCCACCAGCCACAGTTACAACTCTAGATGAAAAACCATTTCAGTATTCAGGAGAGTTCATACTGCCCGATTTTATAAATGAAGCAGAAGAGGACATTAAGAAGAATGACATAACATTATTAAGTACAATAGAGGCTTCGTCGCATTTACCTAAAACAAAGTATGATTCTCTCCGTGTGGGCGTGTATCGAATGTTAATGAATTTCAATTTGAGTGTACTCCAGCAGACAGATAGCAGTATAGATATAGATAAGACACTATTTGATTCGAAGTCGTTTTGTTGTTTTACATGCAAAGAAGCTTTTATTAGTGTTAAAACATTTGATAAGCATTTAAGTGAGCATCCAGCTGAATGCTTTACGTGTGGTAAGAAATTTACCAGATGGACGTATTTTTCGGTACATTTAAAACGGCATTTAGGCTGGAAGGATTTTGCATGTTCGGTTTGTAGTAAAAAGTTTGTTATACGAGTCGCCTTAATAGAGCATATGCGAATGCATACCGGGTTGGCTCCGTTGAAGTGTAAGTTTTGTGACAAACAATTTCGCAGATATTCTAACTTAACGCAGCATAAGAGATTATGTCATTTGAGAGTGACTAAGAAGAAGGATTATGTTTGTCATTGCGGGGAAGTCTTACCATCAAAAGCACGATTCCTTTGGCACAAAGAAACTCACGATACAAAGCCCAAATGTTGCCCATATTGTCGAGATCGATTTGTGCATTCGATCAGCTTAAAACGTCACATTAGGCTAGCTCATTCAGATAAATTCTCATACACTGAACCAGCTGAATGTCCTATATGCAATCAGGTGTATGCTAAAACTAGTATAAAGGCTCACATGAGCATACATTCGATGGAGACACAGCACGAGTGTGTAATATGTAATAAGTCATTTAGCACGAAATGGAACTTGAAGATACATAGTTGGGTGCATGCTAACAGAGCTGCAAAGCCTTTTAAGTGTGACCAATGTGTGAAGGCGTTTGTACGGGAAGTTGACTACAAAAATCATATTAATGCTCATAAGCAAATAAAGCCGTATACATGCGAGTATTGTGGCTGTAAATtcattagaaaatataattatatGCGACATAGTCGAGAGCATCATGGGCAGAAGAAGTTTAGCTGTGATTTATGCGGGAAATTATTTCACAGGCATTATTACTTGATCGAACATAGAAGAACGCACACTGGTGAGCGGCCTTTTTTATGCACAATATGTGGTAAAAGTtcgacaacaaaaacaaatcataATAAACATTTGAAAATCCATCATTCACGGGATCCATTCACTTCAGAgacataa
Protein Sequence
MGEQVPCPVCTLFLHPGMSLADHLETHPKEQVIKALVSLASAFPSNKEQKIASPAQEAPPIIPTIHAAESNTNILSTSESKLGFVAPNKQNVMIVNRQSTMVYQTSDAEHQRPLSQSIPELETTSAMQMFNMPNNQTKILPPPPAYGTAINQLRSQNNNQNFYGRQMQLQQQQYEAENYDYGPPSSNYDYPRTISPARPPSRPTSSPSVLRFAESPVTAHYVERENGDFVVQETPRHVVQCVEKDDGEFSVIEKVIRSPPSVVQFNDNENTENNEINNESNDNDENNTDQYHQPGEPDEVQCDNHEASSETSQIIETQETQQQQKVQPCVTVLSDVKLDPTESLDIMENIIAASKQRKGRLTDLVESVTEVIKKEESEKNLENIFSHLENEDSYNEQFDESCKTDEQKKPWSSAATSVIRLATQQPNTSQEPIQQKDNLKKPGITPKISLPIKRSFRKTPKKLVVKFKNRPKSSNTRETVATTIGPQPGPSDTKEKFVEEPMIDLSTKKPDLIKQQNEQEKNPPEMAEEKQFFEKKLEAITNEKPIEIDEEVDKKDIKPVIEPMMPCVIVHEPTAMDAMEEEMESEIPTEKIETISKEEIKDDKKDSELSKLLEECITNTETDSYSVHLSTIDTIPHAPTGNFIVTDFSESNAFDTQKNEVTNLTPIALTTTSTSSFSKPSTSSFALRDQTDFQSSHSFNDYPFSFLYANSIDKNRLSPIYPGDDQSWHRYSGPIFQQSQQVHNHNDLDGEKNSYIDLDACKKQMCTDTVPLDALNIRTDEKMPAKGEISEQESNGEIDLSWSQPLYHDTQRFSNQLENYVTRGSGSYSNDAFFFYPQDLSTETKPIPSLLPTPEHEKPPESLIKKEPRKTATRGKKTFQCDHCPSSFPKLRERNTHLIEQHNYKRINRRLVREPPPATVTTLDEKPFQYSGEFILPDFINEAEEDIKKNDITLLSTIEASSHLPKTKYDSLRVGVYRMLMNFNLSVLQQTDSSIDIDKTLFDSKSFCCFTCKEAFISVKTFDKHLSEHPAECFTCGKKFTRWTYFSVHLKRHLGWKDFACSVCSKKFVIRVALIEHMRMHTGLAPLKCKFCDKQFRRYSNLTQHKRLCHLRVTKKKDYVCHCGEVLPSKARFLWHKETHDTKPKCCPYCRDRFVHSISLKRHIRLAHSDKFSYTEPAECPICNQVYAKTSIKAHMSIHSMETQHECVICNKSFSTKWNLKIHSWVHANRAAKPFKCDQCVKAFVREVDYKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHSREHHGQKKFSCDLCGKLFHRHYYLIEHRRTHTGERPFLCTICGKSSTTKTNHNKHLKIHHSRDPFTSET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-