Basic Information

Insect: Thereva unica
Gene Symbol: L
Assembly: GCA_949987705.1
Location: OX465281.1:3000706-3005384[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.36 1e+02 5.6 5.7 1 23 71 93 71 93 0.98

2 17 1.9e-07 5.6e-05 25.3 3.1 1 23 99 121 99 121 0.99

3 17 1.6e-05 0.0046 19.3 0.2 1 23 127 149 127 149 0.98

4 17 0.34 97 5.7 0.3 10 23 214 228 206 228 0.90

5 17 0.0015 0.42 13.1 0.6 2 23 251 273 250 273 0.96

6 17 0.032 9.1 8.9 0.3 1 23 361 383 361 383 0.95

7 17 0.0017 0.47 13.0 2.4 1 23 391 413 391 413 0.97

8 17 0.002 0.56 12.7 0.2 1 23 421 445 421 445 0.87

9 17 0.0081 2.3 10.8 1.7 1 23 480 503 480 503 0.98

10 17 0.0012 0.33 13.5 2.9 1 23 535 557 535 558 0.96

11 17 5 1.4e+03 2.0 0.6 1 23 691 715 691 715 0.83

12 17 0.00033 0.094 15.2 4.7 2 23 724 746 723 746 0.96

13 17 0.098 28 7.4 0.1 1 23 752 774 752 774 0.92

14 17 0.18 52 6.6 0.5 2 23 782 803 781 803 0.96

15 17 2.3 6.7e+02 3.1 0.5 2 23 887 908 887 908 0.93

16 17 0.0007 0.2 14.2 0.0 1 23 918 940 918 940 0.98

17 17 0.11 32 7.2 0.3 1 23 947 969 947 969 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.36	1e+02	5.6	5.7	1	23	71	93	71	93	0.98
2	17	1.9e-07	5.6e-05	25.3	3.1	1	23	99	121	99	121	0.99
3	17	1.6e-05	0.0046	19.3	0.2	1	23	127	149	127	149	0.98
4	17	0.34	97	5.7	0.3	10	23	214	228	206	228	0.90
5	17	0.0015	0.42	13.1	0.6	2	23	251	273	250	273	0.96
6	17	0.032	9.1	8.9	0.3	1	23	361	383	361	383	0.95
7	17	0.0017	0.47	13.0	2.4	1	23	391	413	391	413	0.97
8	17	0.002	0.56	12.7	0.2	1	23	421	445	421	445	0.87
9	17	0.0081	2.3	10.8	1.7	1	23	480	503	480	503	0.98
10	17	0.0012	0.33	13.5	2.9	1	23	535	557	535	558	0.96
11	17	5	1.4e+03	2.0	0.6	1	23	691	715	691	715	0.83
12	17	0.00033	0.094	15.2	4.7	2	23	724	746	723	746	0.96
13	17	0.098	28	7.4	0.1	1	23	752	774	752	774	0.92
14	17	0.18	52	6.6	0.5	2	23	782	803	781	803	0.96
15	17	2.3	6.7e+02	3.1	0.5	2	23	887	908	887	908	0.93
16	17	0.0007	0.2	14.2	0.0	1	23	918	940	918	940	0.98
17	17	0.11	32	7.2	0.3	1	23	947	969	947	969	0.96

Sequence Information

Coding Sequence: ATGACTGGTCAAGGTGCAGCTCTCAAACTCATCATCGCCTCTGAGTCGACTCTTCTAGTCACCGTAGGAGTTTATCAGTTCTGGCAAAATCTTACCGCAATTACCACAGGGTGTATTCTTGAACTTTTACaacatcaaaaatttcaaacacaGGGCTTACTTCTCATGCATCCTCAGACTCCCCTTAACAGCCATGCGGAGCACCTGCCCTTCAAGTGCGAGTACTGCGCTCGATTGTTCAAGCACAAACGTTCCAGGGATCGGCACACCAAACTCCACACCGGGGACCGGCGCTACCGTTGCCCACACTGCGAGGCAGCCTTCTCGAGGAGTGATCACCTTAAGATTCACATGAAGACGCACGACAACCAAAAGCCGTTCCAGTGCACAGTATGCAACAGGGGCTACAACACGGCGGCGGCGTTGACGTCGCACATGCAGAACCACAAGAAGCAAGCTGCTCTTTTGGGCAGTGGCCAGAGCTTGAATTACAGTCCGCGCTCGACTGGATCTGGATCGAGCAACGGGAGCTTCCATAAGAGACGTTACGCAACCGCGGAGAACAGCCCCAACAGAACGGACTTCAGGAAGCACGTCCGCGGCTCCTACATCGCCTGCATTTACTGTACAAAATCCGATTTCACCACTTTGGAGCAGCTCAACAGCCACATCCAAACCATGCACGAGAACGTCGCAACCAAAGACAACGCACACCACCCGATGGGCAACAATCAGGCCGTTTTCCAGCTCTCCTGCGAGTACTGCACCATGAAGTTCCCCAACATCCCTTCCATGTTCCAGCACATGCGAACGACCCACATCGACCGCTTGGCGAGCCCGAATTCGTACTTTGAGCACTTCAACAGACTTGCAGCGTCGGGGACGTTCAGCCCCAGGCTGGCTACCAACATGCGTTTTGAGGAAATGAAAGTGAAAACTGAGGAGCCCAGTCCCAAGGCGGACCGTCAAACAGAAACCGAGAAGGACGACGAGCAGCAAGGCCCGACAGACCTTAGTCAGCCGAAGAAGAGGTCGCAAACGCCCTCGCAGGTTTCGGATAATTCAGACAAGCCCGGCGCGTTTCTGTGCAACCAATGCAACGCGGGACTGCCTGACTTCGACACCTTTCGTGCCCACCTGAAGACCCACATAACTCAAGGTGTCACCAACCACGTTTGTCATCACTGCGGCGTCTCACTGCGGGACCAAATCGAGTACGAACGTCACGTGATCTCGCACTTCCTAATATCCAGCTCGGAGTACGCCTGCGCCAGTTCCTGCAACAAAGCGTTCCCGAAGCCAGACGACCTGCAGAAGCACCTCTTCGAAAACCACGTGCAGACGATGTACAAATGTTCCTTATGCTCCGACTTGTTCGACACTAAGGTGGCGATCCAAGTCCACTTCGCATGCGCTCATTCCAATGAAAGTAAGATCTACCGATGCTCAGCGTGCATGGAATCGTTCCGATCGGAGAAGGATTTCACTACGCACGTAAGGACGCGGCACTCGAACACTGGATCTATTCAGTGTATGTTTTGTCGAGCGGTTTGCTCCTCGGAACTGGAAATGCACTTTCATCTTGCAGCGCATGCTCGGCAGTTCAGGTGTCCGTCATGCCCGGAAACATTCCATGTGGAATTCCTGCTCGATCGGCACATGCAGACGCACCACGCTCAGAAAGACGGTGCTCCGGTAGCTGCGGCAGCAACTCCGCCTAATCCGCTGTATCAAGGTCAATTCGCGAAAACcccgaacaacaacaacaacattctAGACTACCACGCCTTTGCTGCCAGCAAGGGGCTGTTTCAGCTGCCGGGGAATAAGTTCTACAGTCCGCTGCAGGTGGACACCAACGCTTTGAACCCAGCCAACAAGCATCCAGCTCTCATGTACGGCTTGGGACAGAGATACTTCGACACGAACAAGACTCTTCTAGACATGTACAACTACCACCAAGAAAAGGCGAGTTCGACATTCTTCGCCAGTCCGAGTGGGTTTGAGCCCAACCGGACTTCCAAGGTGCCGTCGGAAACTAAAGCTGTGGAACGCCCACACACCAACGGCTTCAGCTGCGGCATCTGCGAAAGAAGCGATTTTAGAACTGAAGCAGAGGTCCACTCCCATCGGAAAATAGTTCATAACCTCAAAACAGGCGTCAGCTTGCGCTGTGCCTACTGCAACGGCAACTTCAAATCCCGCAGCGAACTGGAGCACCACATGAAAACATGCCACAACTCTACAGGAAAGCACAAGTGCTTGATATGCGACGAGATCTTCCCATCGCCAGCGATTCTAGCCGAGCACAAGCTGCAGCACTCCAAAGTCGGCCAATCGGGCAAGTGCTCGCACTGTTCGGCCGCTTTAAACGACGTCTCTGCCTTCAAGTCGCACCTCTCAGAGCACAACACCGAAGGTCAAATTCCCGTTCAATGCATTTGCTGCCGGCAGACTCTCAACTCGGACTTTGAAATCGGACTCCACGCCAAGTTCCACACGAAATCCTCGGGTACCCCCGAAAACCTCTGCGCCTTGTGCCTGGAAGCAATTCCATCTAACTCCGAAGCCCGGGTTTGCGAGAAATGCTGCCGCAAACACAATCTCACCTCAAAGTTCAACATGCGCTTCGAAACGTCACGAGCCTACGTAGAGAACCGGTGTAACTTGTGCAAGATGATCCTGCCGCACGCCCAAAGGCTGCAAGAGCACTTAGTGGAGCACACCTTCGTCGGCTGCGAAGAACGCGGCTATTCCTGCTACATATGCTCGGCCGTGTTCACAGTACCAGCGGGACTCCTCACGCATATGAATGAGCACGGCCCGAACGCCCGTCCCTACGACTGTAACTTGTGCTCCGAGAAATACTTCTTCAGAGCCGAGCTGGACAATCATTTGATAGAGCACGAGAACCGTGGGAAGACGGATATCAAGAACGAAACGAAGCAGCCCCAGCCGCAGCAACCGCCGCAGCAGCAGCAAATCCATGAAAACTCCTCATTGGAAAGCGGCGAGGAACCCAAGCCAGAAGTTAAGACCGAAGCCGCCGAGGAGCCGGAAGACGATGAGGAATACATCGAGGTGGAGAAAGTAGCCGAATCGAATCCTCCTGGCGAGGACGACGATCAGAAGGAGACTTGA
Protein Sequence: MTGQGAALKLIIASESTLLVTVGVYQFWQNLTAITTGCILELLQHQKFQTQGLLLMHPQTPLNSHAEHLPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLGSGQSLNYSPRSTGSGSSNGSFHKRRYATAENSPNRTDFRKHVRGSYIACIYCTKSDFTTLEQLNSHIQTMHENVATKDNAHHPMGNNQAVFQLSCEYCTMKFPNIPSMFQHMRTTHIDRLASPNSYFEHFNRLAASGTFSPRLATNMRFEEMKVKTEEPSPKADRQTETEKDDEQQGPTDLSQPKKRSQTPSQVSDNSDKPGAFLCNQCNAGLPDFDTFRAHLKTHITQGVTNHVCHHCGVSLRDQIEYERHVISHFLISSSEYACASSCNKAFPKPDDLQKHLFENHVQTMYKCSLCSDLFDTKVAIQVHFACAHSNESKIYRCSACMESFRSEKDFTTHVRTRHSNTGSIQCMFCRAVCSSELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHAQKDGAPVAAAATPPNPLYQGQFAKTPNNNNNILDYHAFAASKGLFQLPGNKFYSPLQVDTNALNPANKHPALMYGLGQRYFDTNKTLLDMYNYHQEKASSTFFASPSGFEPNRTSKVPSETKAVERPHTNGFSCGICERSDFRTEAEVHSHRKIVHNLKTGVSLRCAYCNGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSAALNDVSAFKSHLSEHNTEGQIPVQCICCRQTLNSDFEIGLHAKFHTKSSGTPENLCALCLEAIPSNSEARVCEKCCRKHNLTSKFNMRFETSRAYVENRCNLCKMILPHAQRLQEHLVEHTFVGCEERGYSCYICSAVFTVPAGLLTHMNEHGPNARPYDCNLCSEKYFFRAELDNHLIEHENRGKTDIKNETKQPQPQQPPQQQQIHENSSLESGEEPKPEVKTEAAEEPEDDEEYIEVEKVAESNPPGEDDDQKET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00628637;
90% Identity: iTF_01431345;
80% Identity: -