Basic Information

Insect: Thereva nobilitata
Gene Symbol: ZEB2_1
Assembly: GCA_963855945.1
Location: OY979695.1:164653454-164663737[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 1.1e-06 0.00026 23.0 1.7 2 23 514 535 513 535 0.97

2 4 2.3e-06 0.00056 21.9 1.8 1 23 541 565 541 565 0.97

3 4 1.1e-06 0.00026 23.0 3.4 1 23 571 593 571 593 0.98

4 4 0.00025 0.061 15.5 0.6 1 23 603 625 603 625 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	1.1e-06	0.00026	23.0	1.7	2	23	514	535	513	535	0.97
2	4	2.3e-06	0.00056	21.9	1.8	1	23	541	565	541	565	0.97
3	4	1.1e-06	0.00026	23.0	3.4	1	23	571	593	571	593	0.98
4	4	0.00025	0.061	15.5	0.6	1	23	603	625	603	625	0.97

Sequence Information

Coding Sequence: ATGTCGGGATACCGGAGTGTGAATTATTATGATTTATGTCGTCTATGCACGACTAGCAGCGGcacaaaaattcatattttttcagctgaaggaaagaaaaagaatttgtaTCAGAAAATATCGGAATGTCTACCGATTTCGGTAAACGAGGAAGACAAGCTACCAAAAATATTATGTGGGCAGTGCTTACAGCAAGTAGAAACAATTTCCGAATTCCGGAATACTTGTATCAATTCACAGGCAATGTTAGAGGGATGCCTTTCCTCAACATTACAGAATGGAGGAAAGGTTTATATAAAAGATGCAACCCCACGAATTGTTAATACCCAAATAGTGAATCAAATAAAACAACCTGTGAATACAAATACGATTACGACAACACACAATTCCGATTTTCTAAGTAGCATTATTCAAGCTGTTGGGATTCAAACAAATGACGAAGTTACAGTTGAAAACCGCACGAATTCTACACCTCACTACACCGTGACTTTAGATGGCAAATCAATAAACACTGGACAAATCCAATATAAAGTAGAAGATAGTAGAAACATTACTCTGCACTCTGAAAAGCAAGCGAAGCAAAAcTCTCTGGCAGAATTCTTGAAAATGAAACCGAATATTAAAGTTACACCAATATCTAAAAAGAAAGTGGAAAATACACAACAAACCCAAGTACAAGTACAATCGCCAATAACAATAACACATCCAGAAACACCGAAAATGAAAAAACCTAAATATAATATTGTACTTACGTCACCATCTCAACAAAAACAGCATATAATACAAAATGCTGTTACACCAACAACGACAACAACACAAATTCATCAGCCATCTACATCGATTGGGAAAACAGTTTCCTTGCAAGatgttaaaataatttcacCCGGCAATAAATGCTTTCTACCAATTACATTAAAAGACTGCAATTCAGATCAACAAATCGTTGCTCAGattgatacaaaaaatttagttttaccAACAACTTACCACTTACAAATGAAGttaCAACCGCAATTGGCTACCGTTGATGGACAACCAATAATGCAACTAACACCAACAGCCATTCCAGCCACTCTGTCAATAACTCCAACACAAACAATATCACAAAATTATCAAACAGATCACACGAACACAAATCAAATCTTGTCGAGTGGAATTGATGCATCAACTTCAACAAATGAGccagaaattatttttaccaCAACAGCGAATCAAATGCAGACCCATCAGCAGGCCATAACTATTCAACCAATAACGCAACCAACAACACACCAGACAACTATGCAAAAGCTACAAATAACGACCATACCCACATCAATTGGAACAACACAAATTCAAACTgttcaaaatcaaaaaacacaGAGTGCAATAACAGTTCAAAGGATCAATCCACagcatgtaaaaataaaacaggAACCCTCCGTCAAGCTGCCCACCCAACCTCAACAAACTGTTCAGCAGACTACGAAGGCTGTCACTGTAACGACTAGTTCAAATATAAAACCTGAGAGCCCGCAACAAAGTGGCGGCCCTATGCTGCAGTGTACTGTATGTGGGCGAGCATTTAAGAAGAAGGAGCATCTTGCGCAACATATGAAACTGCATGCTGGCCTGCGACCCTTTAAGTGCACAGAACCAAACTGCAACAAAGCATTTAGTAGAAAAGAACACCTTATGCGACATATTGTCTCTCACACAGGCAAGAAAATGTTCAGCTGTGATATGTGTCAGAAGCTTTTTTCAAGAAAAGATAACCTTAACAAACATAAAAGAACCCACAGTGAACAAGGTGGAAGTAATACTCAGTTCGTTTGTGAAGTATGCAATAAGAGTTTTGTAGTAAAAATGTACTACATTCAACATAAGTTAATGCATGAAAAGAACGGCCAGACAGCAGGATCTGTTAAGCCTAAAaatGAAAAAACTGAGCAAATTACAGAAGATGTAAATGCTACGAACAATCAAATTCAGACTGTAATGACCCAACAGACCCAGCAGCAACAACATCAGCAGCCACAAATGATGCAGCTGCAGATATCATCACCAGTTGTAACAACATCAGGTGGTAATACGATATCTATTAGTCAGGCCCCTGATCATCAACAGCATACAACAACAACGGTTCTTAAAGCATTGGGAACTCATGACACTGCTGTCCTTAATTTGCCATCAAGTTTAGCTAATTTAGTATCAATAAATTCAGCACAGTTTATGACCACCTCCGATTTAATGGGACATATTAAAATagagaataaataa
Protein Sequence: MSGYRSVNYYDLCRLCTTSSGTKIHIFSAEGKKKNLYQKISECLPISVNEEDKLPKILCGQCLQQVETISEFRNTCINSQAMLEGCLSSTLQNGGKVYIKDATPRIVNTQIVNQIKQPVNTNTITTTHNSDFLSSIIQAVGIQTNDEVTVENRTNSTPHYTVTLDGKSINTGQIQYKVEDSRNITLHSEKQAKQNSLAEFLKMKPNIKVTPISKKKVENTQQTQVQVQSPITITHPETPKMKKPKYNIVLTSPSQQKQHIIQNAVTPTTTTTQIHQPSTSIGKTVSLQDVKIISPGNKCFLPITLKDCNSDQQIVAQIDTKNLVLPTTYHLQMKLQPQLATVDGQPIMQLTPTAIPATLSITPTQTISQNYQTDHTNTNQILSSGIDASTSTNEPEIIFTTTANQMQTHQQAITIQPITQPTTHQTTMQKLQITTIPTSIGTTQIQTVQNQKTQSAITVQRINPQHVKIKQEPSVKLPTQPQQTVQQTTKAVTVTTSSNIKPESPQQSGGPMLQCTVCGRAFKKKEHLAQHMKLHAGLRPFKCTEPNCNKAFSRKEHLMRHIVSHTGKKMFSCDMCQKLFSRKDNLNKHKRTHSEQGGSNTQFVCEVCNKSFVVKMYYIQHKLMHEKNGQTAGSVKPKNEKTEQITEDVNATNNQIQTVMTQQTQQQQHQQPQMMQLQISSPVVTTSGGNTISISQAPDHQQHTTTTVLKALGTHDTAVLNLPSSLANLVSINSAQFMTTSDLMGHIKIENK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01432573;
90% Identity: iTF_01432573;
80% Identity: -