Basic Information

Gene Symbol
-
Assembly
GCA_963855945.1
Location
OY979697.1:15965446-15969248[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 6.1e-05 0.015 17.4 0.8 1 23 152 174 152 174 0.97
2 15 4.2e-05 0.01 18.0 0.6 1 23 180 202 180 202 0.97
3 15 0.00054 0.13 14.5 0.1 1 23 288 310 288 310 0.98
4 15 0.0091 2.2 10.6 2.1 1 23 316 338 316 339 0.96
5 15 3.7e-05 0.009 18.1 3.5 1 23 366 388 366 388 0.97
6 15 0.0045 1.1 11.6 0.2 1 23 401 423 401 423 0.94
7 15 0.098 24 7.4 0.2 1 23 429 452 429 452 0.91
8 15 0.34 84 5.6 0.6 3 19 461 477 460 478 0.94
9 15 8.6e-05 0.021 17.0 5.9 1 23 487 509 487 509 0.96
10 15 0.015 3.6 9.9 0.5 2 23 515 536 514 536 0.96
11 15 7.4e-06 0.0018 20.3 1.0 1 23 544 566 544 566 0.98
12 15 0.0038 0.92 11.8 0.2 3 23 574 594 572 594 0.97
13 15 4.5e-05 0.011 17.9 0.5 1 23 600 622 600 623 0.95
14 15 0.24 59 6.1 0.0 1 23 633 655 633 655 0.97
15 15 0.0023 0.57 12.5 0.0 1 20 1033 1052 1033 1055 0.94

Sequence Information

Coding Sequence
ATGAACAATTCAAATTTCCAAATACAATGGGTTCAAGAGATTGACCATGCAACACAAATCGTCAGCGAAGAAGTAATTACAATAGATGCCCAAGACGATGAGGATGAAGGGACTGAGCAGCGGTACCTTGTGCATGAAATATCCTCAATGCCAACCAGCATCGATCAGATAGCAGCAGAGAATCTTATCTACATGGCACAAGATGGTCAGGTTACAACAATGGATGGCTTAGTACAAAATGTTGAAAGCCAAAATATTGACGATCATCAGTATTTTGAATGCCAAGTTACAGAAGAAGTTATTACCGATGACTGGGTACAACAACAAGGCGAAGAGAGAGTGGAAATACCAGTCGATCAACTTTGCGGATCTGGTGGCGGTGAATCTCAACTCGTAGAGGAATTAGATGTTCCTCTACCAACTGATCAAGATGAATATACAGCTCTGCGGCCATATCCTTGTGATTTCTGCAGCCGTCGCTTTCGAAAGAAAGTAAGCTTAATGAATCACATGATTGCGCATCAAAATGATCGTCCGCATGTCTGTAATTTATGTGGTGCCCGGTATATTCGTCGTAGTGatttattaaatcatttaaagATTCATGCTCATATTCCTGATACAAAGGGAGAGGATGTTGATGatTTCTATCAAGTCTTAAATGATCATATTGAAGCTAGGCCACCCAGACGAGGAGATTATTATGAGCATGATTTCTATGAGGAAAAACCAAAGACAAAGACTCGTGGACGaactaaaaaaatgaaaatcaaaGAAGAACAAGCTTATATCGAAGAGCCAGATATAGAAGAGACAATAACTGAACAAACTCGATATCCTATTATTGATCCAAATAAGCCATTTGTGTGTCAACAATGCGGCGTTGGTTTTGCTAGAGAAAAGGCATTACTTTCTCATTCAAGagTACATGGTAGCGATTCGCCTTATGAATGTGGAAGCTGTAACGAAATGTTTTGGGATGTTAGCTCATTGCATGATCATCAAAGGACACATCATTTTGAAGCAAGCAATTCAGAATATGAGCCTGAAAATGATGAAGAAACTGAATCGGATAATGATTCAAAATATGGTGATTTTTATTGCAGTGTTTGTGGAATGTCATTTCACAGACAAGATTTATTAAAAAGACATTCAAAAAGTCATGTTAAACGAGAATTTGCAGAAGAAGGTGATTCAAGGCATTGCTGTAATGTTTGCGGTGAAACATTTGCCGAAGCATTAGATTTGTTGGCTCATGCAGAAATTCATGCTAGATTTCAGCCATTTAAGTGTGTCCTATGTGGTGAATCATTTCTAGAAGAATCTACAATAAAAAAGCATTTGGCAAATGTTCATTCGTCTGAGATGAATGCAAACTCCTGCAGATTATGCGGAAAACAATGTCGAGATGGACGTGCATTAATGAAACACGCATGGGATCATTCTAgagaaaaaaatcattcatGTTCGAAATGTGGAAAAACTTTCCATAATAAAGCAAGACTTAAAAGACACATGGTTTCACATCGTAACAAATCTGTTACTTGTGATGTATGCCAAGAGGAGTTTCCCGATGGTCGTTCACTTATGAACCATCGTCATTCTCATACCAATTCTTCTGGACGCCTATTCCCGTGCCATGAGTGTGGAAAAACATTTGGATCCCGTAGCTCACAGCAGATACATGTAAGAATTCATACTGGAGAGAGGCCATATGGATGTAGATTTTGTTGGAAAGCATTTGCTGATGGTGGAACTTTAAGGAAGCATGAACGAATTCATACtgGAGAAAAACCGTATGCATGCTCAGTATGCCCCAGAGCCTTCAATCAAAGAGTTGTGCTTAGGGAACATATTCGATCACATCATTCAGCATTGGATAATAAGACAGGAACATACTACTGTACAGTGTGTTCAGATGTTCTTCCATCTTCAGTTGAACTTATACAGCATTTAATACAGCACAGTGATATGAATACTGCCATGCAACGACAGCCTATTactgGTCCACGTAAGTATAAGCGACGAAGAAAACTCAAACCACatgaaatcgaaaaattacGGCATGAAAAACCAAACAGTGACATTGATTATTCTGACTTGGATATGGGTAATGTAGACGATTTACTTGGATTAAGTACCAAAAATAAACGTAGCCGTACAACGACAACATCATCAATTACAAATACAACAAGTAGAAATAGAAAATATTCTGGAAATTCTGATAAATTAACTAGCAGCTGGCATAATAAGCTAATGTCAACAGCTGATGATtctttaaattcagtttttaataatttagaaaatgcattgcaaaatattgaaccgcTTGTTGTTAATAGCAGTTCAGCAAATGATACAATTGTTACACCAGCTAAAActaaaacaacagcaacaaaaaggaaaaataataagaatGATTCTGCTGATAAACCGTCTAGGCCTAAAATGATACATACGCAGAAGACTCGAGTCGCAGCTGAGGATGGTAAACGAAAAACTCGAACTTTAATTACACGAACTGAGCCAGCTGAAATCGATGAACAGGTATTTAATCAACTTGATCGAGTAAAAGGTTCTAGAAAGCGCGATAATAGCACGAATAGTGATTATGAATTGATATTAAATGATCCTTCATCAGAATCTTCAAATCGTACTGCAGTCAAGCAGGAACAGACATCGCGTAGCGATTTATTCGATGCTCAGTTGCTACTAGAAGCAGCAACAATGCGTAAGGAGCTTGAAAAGTACAATCCTGATGTAGTTAATGatttagaagaaatattacgttctccaattaaaacaaaacaatcgCCACGTTCAAATACAACACCAAGTGTCTCGGATTATCAGCCAGAAGTTGAGGAGCCAGTTCATGAGGAGACAGAAGATTTACGTCGATCTACACGTATTAAAAGATCATCAGCTGCTAAAAAGTATATCGATTTTGAAACATCATTAAAGTTATCACCAACGTATAAGACTCCGCAAGCTCATAAAGTTAAGCACGAAAAACATGagaaagttgaaataaaaattgaaaagtcTGAAACTATGAAATCTGAGCCAGGATGCTCACCAGGTAAAGCTGAATACTTTCAGTGTGAAATGTGCAGTGCAATGTTCACTGATCGTGCACAATTGCTTGTTCATGTTCCAATTCATATTTAA
Protein Sequence
MNNSNFQIQWVQEIDHATQIVSEEVITIDAQDDEDEGTEQRYLVHEISSMPTSIDQIAAENLIYMAQDGQVTTMDGLVQNVESQNIDDHQYFECQVTEEVITDDWVQQQGEERVEIPVDQLCGSGGGESQLVEELDVPLPTDQDEYTALRPYPCDFCSRRFRKKVSLMNHMIAHQNDRPHVCNLCGARYIRRSDLLNHLKIHAHIPDTKGEDVDDFYQVLNDHIEARPPRRGDYYEHDFYEEKPKTKTRGRTKKMKIKEEQAYIEEPDIEETITEQTRYPIIDPNKPFVCQQCGVGFAREKALLSHSRVHGSDSPYECGSCNEMFWDVSSLHDHQRTHHFEASNSEYEPENDEETESDNDSKYGDFYCSVCGMSFHRQDLLKRHSKSHVKREFAEEGDSRHCCNVCGETFAEALDLLAHAEIHARFQPFKCVLCGESFLEESTIKKHLANVHSSEMNANSCRLCGKQCRDGRALMKHAWDHSREKNHSCSKCGKTFHNKARLKRHMVSHRNKSVTCDVCQEEFPDGRSLMNHRHSHTNSSGRLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSALDNKTGTYYCTVCSDVLPSSVELIQHLIQHSDMNTAMQRQPITGPRKYKRRRKLKPHEIEKLRHEKPNSDIDYSDLDMGNVDDLLGLSTKNKRSRTTTTSSITNTTSRNRKYSGNSDKLTSSWHNKLMSTADDSLNSVFNNLENALQNIEPLVVNSSSANDTIVTPAKTKTTATKRKNNKNDSADKPSRPKMIHTQKTRVAAEDGKRKTRTLITRTEPAEIDEQVFNQLDRVKGSRKRDNSTNSDYELILNDPSSESSNRTAVKQEQTSRSDLFDAQLLLEAATMRKELEKYNPDVVNDLEEILRSPIKTKQSPRSNTTPSVSDYQPEVEEPVHEETEDLRRSTRIKRSSAAKKYIDFETSLKLSPTYKTPQAHKVKHEKHEKVEIKIEKSETMKSEPGCSPGKAEYFQCEMCSAMFTDRAQLLVHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01432454;
90% Identity
iTF_01432454;
80% Identity
-