Tobe017985.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Thera obeliscata
Gene Symbol
znf423
Assembly
GCA_947578465.1
Location
OX387925.1:7692342-7700812[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.0034 0.21 12.5 2.5 1 23 64 86 64 86 0.98
2 20 0.063 3.9 8.5 3.1 1 23 344 366 344 366 0.97
3 20 1.6 99 4.1 4.3 1 23 632 655 632 655 0.97
4 20 0.53 33 5.6 3.2 1 19 660 678 660 683 0.90
5 20 4.1 2.5e+02 2.8 3.3 2 23 687 708 686 709 0.93
6 20 0.0033 0.2 12.6 0.2 1 23 713 736 713 736 0.97
7 20 0.0043 0.27 12.2 0.8 3 23 800 821 798 821 0.92
8 20 1.4e-05 0.00086 20.0 2.7 1 23 827 850 827 850 0.96
9 20 0.048 2.9 8.9 0.6 2 21 854 873 853 874 0.93
10 20 0.013 0.81 10.7 1.5 1 23 882 905 882 905 0.94
11 20 0.00019 0.011 16.5 0.7 1 23 910 933 910 933 0.96
12 20 0.028 1.7 9.7 0.3 2 23 946 967 945 967 0.95
13 20 0.0029 0.18 12.8 1.0 1 23 973 995 973 995 0.97
14 20 6.7 4.1e+02 2.2 0.4 2 10 1001 1009 1000 1018 0.79
15 20 0.0004 0.025 15.4 0.3 3 23 1033 1053 1031 1053 0.95
16 20 2 1.2e+02 3.8 1.3 3 23 1059 1079 1058 1079 0.84
17 20 0.0063 0.39 11.7 2.7 1 23 1096 1119 1096 1119 0.97
18 20 5.1e-05 0.0032 18.3 3.6 1 23 1125 1147 1125 1147 0.99
19 20 0.0014 0.085 13.8 6.5 2 23 1154 1175 1153 1175 0.96
20 20 0.024 1.5 9.9 2.2 1 23 1181 1204 1181 1204 0.96

Sequence Information

Coding Sequence
ATGATTGCGGCCGATCATTTCAAAGTTGTTGAGTACGCTGATCCCTTATTCCACATCATCAATACTCACTCTGAAGCACTATCAACTGAACCTGCAATAAACCCACTTGAATGCCTGAAATGCTGTCAAGTCCTACCAAATGTGGAATCACTGGCGAACCACTCAAAAATTCACCCAGCGTCCATGTGGTTTACTTGCAGACTCTGTTCAAAATCATTTCCCAAACTGTACTTGATCAAACGGCATTATCGTGATCATCAACAAGAGCTTCTGCATCCAAACTTAAATGATAAAAAGTTTGAATGCAAGGAATGCAGCGAGTTGAGTAAAAATTATTACGAGCATTTGCAGCATCTGGAGAAACATCATTTTAAAACCGTCTTGGAACATCTTTTAGATGAACAGATGAATAAGTTGTGTGCTGTTTGTATGAACAGAGGCACCTTAGTGCCGTTAGATGATATTATCTGTCTGCATGGTGGGCCTCCAGACTTGATGGGAGATCGAACGATACAAAGCATTTTGGATTTTACACTGCCAGAGTTGCAGAAGAATAATATGGAGGAATATACTGGATCTAAAATTTGCGAAAAGTGTTTAAATAGTGCTCTAACATCTTATACTTTCATGCACAACACTTATTTTGCAAGAAAGAGGCTAAACACATGTGTTACCCACATGTTAGATAGCTTGAAAGGCATAAAACCAGAAAAAACATTATGTGTTGAGATAGCTAAAGATACAATCCTGCCTATAAAACTTGATGAAATGGATTTATTTGACAACTTAAAAGAAAAAGAGGAAGCTGAGAAGGATATTAATAAGGAAGTATTCTTAGAAGATGAGTACAGGATGAAATCTGAAGATGAAGAACCAGAAATAGAAACAAAGTTGAAACCTCATGTAGAATTGAAAGGTCCAAAAACTGAAGTTAAAAAAGAAATACATTTAAATGGGTTTCAAAATAATGTCTGCAGTGAATTCCTCACATTCAACAAAAGACCCAAAATACAAAAAATCTGTAAAAGATTTACATGCCCGATGTGTGACAAACATTTTCTATCAGACTATTTTGTAAAGAAACACATTTTGAAACATGTTAGTTACAAAGTCAGCAGTAACTGCCTGCCTGCCTGCACGTTCAGAATGGACTGTACCCTGACCAAGCTGAGAACCCAAGAGTTGATAAACACAGAATGGCTGAAATCACGCATGAAAGCCATCTGGACCTCACCAAGATACTGTGCTCTGTGCCTCAGTTCTGATGCAGAGTTCTTTGCTTTGAGCATGGAGTTTACAAGCAATGAGCAAACTCTTTCAAAGCCTATGAGAGATGTGGTTAATTACGTGTTTAATTTTGACATTGAAACCTGTATCCCAAGTGACTACATATGCGTGCACTGTGCAGAAAAAACTATACAAACATACACTTTCATAACCGATACCAAAAAAACATATGAAATATTGGATAACTGCTTGAACGATATGAATTCAAAAGTCAATGACATTAACAACACATTGAGTGAAGACACACAATATGAAGATTCAAATGTAGTGATTGTCGTTGAATGTGATACTGAGACTTATGGAAAAATAAGTGAGCTGGCATCATCCAATAATGCTGTCTTAGTTGATGAATCAACCAATGTCAAAGTTGAGAATAGTCCAAGACCGTCAGACCCAATCACTACAGTAGCTAGCAACGAGGAAAACATTGGGCCAGTACTCATTCCAACATTGAGGGTAGTCAAACATCCAAGGAAAAAAGAGGTTGAAAGAAAAGTTGATTATGAAGAAAAAGTTTCTACTCCAAACATAACTCTCCAAGAAGGTAAATTGGTGATAGAACCTTTGGTAACAAAGAGTATACCATCTACTGCAAGATTCAACACCTACTCCTGTCACTCGTGCACGGATATCTTCACCACATACAGATCTATGAAGGAGCATGAAAAAACTAAACATAACTCCGTCATCTACAAATGTAGATTTTGCACTAAAATCTACAATACTCAACAGTATCTAGATGTCCACTGCTTATCAGCTCATAAGAAATCTAGATGTAAATTCTGTAAAAACATGTTTGATTCCGAATCACTGGACAGTCACTTGAAAGAGAAGCATCATCAGTTGATCTATGCTTGTGCCGACTGTAATCTTGTCTACTATAACTCCGAAAAGCTTGACACTCATATCAAATCGAGCCACATCAAGCCTACCCTTATGACTAATGTGAAGAAGCACTGCGTTATGTGCTTAAAAAATTTGAAAGACGCTGAAGTTCCTTCTCACAAATGTAAATTTAATTGTCTAGAATGCCCTACAGTTCCTTGTGTTCATTATAGTTACCTCATGTCTTATAGAGAGCAAGTCTTGAACCGTTCCCCGATAATTCGTTGCATAGACTGTGACTACACCACTAAGAGGAAGGAACATCTCATCGCTCATGTTAATAGAGAGCATTTAGACCATCATCCATTCACATGCAACGATTGCGGAACACAGTTCTACACAAAACAGTCTCTTAAAACACACATGATGCAGTTCCATCAAGATTTGAAATGCCAGTACTGCGATTCAGACTTTAAGAACATGAAACTACTGAAAATGCACCGACAAGCATGTAAAGAGAGTACTAGGAGGCATAACTGTGAGAAATGTGTAGCATCTTTTGATACTTGCCAAGAGTTGGAAAAGCATATCGCAGTCAATCATAGCGAGTTTGTGTATCCTTGTTCACTTTGCACCAAAGAATTCCCCAAGAAAGACAATTTGGAGGAACACCATGCGAGGGTACATAACGGAATCCAATACAAAAAGCGACGGAAGATGATTGAATGCACTCTCTGTGATATCACTTTCAAAACCATCAAAGAAATGCTTGAGCATGAAAAACAACATCCACCCAACGAATTGTTTCCTTGTAAAGTGTGTCCGAAGAGTTATCGAAACCTTAAGTTAGTCTACATTCACAAACAAAAGCACTATTCCCAGAGGAAGAAATGTCCCGGCTGCAATAAAGCTGTGGCGGTCTCATACTTCAAGCAACACAAAGCTTTATGTGTGACTCTGAGGAAAATAGAGCCAGCTATAATCTGTGAAGTTTGCGGCGAAGTCTTCCATTTGCAATCCAGTCTAAAATCCCACCAGCTACTCCACGACAAGCCAGAGCCATGTGTGCATTGCGGCAAGAAAATCAAATCGGCATCTATGAAAAAACATCTAGAATTAAAACATGAATCATATGCTGACCAAGACGATATTTCCATTAAGTTAATCCAGCTTCATAAGTGCAGAGATTGTGGGTTTGTGACTCGCAAGAAAGGAGAATACGAGAACCATAGGAATAAAATACATTTAAAGATCAAACCATACAGTTGTGATGAGTGTAGTCGCACGTTTTGCGTTAAGTCTAGACTGAGCGAGCACATGCGAACTCATTCTACAGCCAATTCTTGCTATTGTTCGTTCTGTGGAAAGAAATTTGCTAACAAAGTATGCTTGAAGATGCACGTCCGGAGACATACCGGTGAAAGTCCCTATGAATGCAACATTTGCTTCGAAAGATTCCGTTCTTCCAGTATTATGAAGACTCATCGGTTGAAGAAACACCAGGATAAGACCATAGCCTGTCCTTTATGTGATGCTATGTACCACATAGTAGCCGAGATGAGGTTCCATGTAAAGAAAACCCATTGGAAAAGTTCTGAGCCGTTTGATTATAAGAAGATTGTGCCGGAAAAGTTTCACCATTTGTTCCAAGATAGGAGACTGACGAGGTTAGGTGATGAGTCTCTGGTTATCACTGAGAGTATGGTAGGTACTGATGAGTATATGCAGGGTTGA
Protein Sequence
MIAADHFKVVEYADPLFHIINTHSEALSTEPAINPLECLKCCQVLPNVESLANHSKIHPASMWFTCRLCSKSFPKLYLIKRHYRDHQQELLHPNLNDKKFECKECSELSKNYYEHLQHLEKHHFKTVLEHLLDEQMNKLCAVCMNRGTLVPLDDIICLHGGPPDLMGDRTIQSILDFTLPELQKNNMEEYTGSKICEKCLNSALTSYTFMHNTYFARKRLNTCVTHMLDSLKGIKPEKTLCVEIAKDTILPIKLDEMDLFDNLKEKEEAEKDINKEVFLEDEYRMKSEDEEPEIETKLKPHVELKGPKTEVKKEIHLNGFQNNVCSEFLTFNKRPKIQKICKRFTCPMCDKHFLSDYFVKKHILKHVSYKVSSNCLPACTFRMDCTLTKLRTQELINTEWLKSRMKAIWTSPRYCALCLSSDAEFFALSMEFTSNEQTLSKPMRDVVNYVFNFDIETCIPSDYICVHCAEKTIQTYTFITDTKKTYEILDNCLNDMNSKVNDINNTLSEDTQYEDSNVVIVVECDTETYGKISELASSNNAVLVDESTNVKVENSPRPSDPITTVASNEENIGPVLIPTLRVVKHPRKKEVERKVDYEEKVSTPNITLQEGKLVIEPLVTKSIPSTARFNTYSCHSCTDIFTTYRSMKEHEKTKHNSVIYKCRFCTKIYNTQQYLDVHCLSAHKKSRCKFCKNMFDSESLDSHLKEKHHQLIYACADCNLVYYNSEKLDTHIKSSHIKPTLMTNVKKHCVMCLKNLKDAEVPSHKCKFNCLECPTVPCVHYSYLMSYREQVLNRSPIIRCIDCDYTTKRKEHLIAHVNREHLDHHPFTCNDCGTQFYTKQSLKTHMMQFHQDLKCQYCDSDFKNMKLLKMHRQACKESTRRHNCEKCVASFDTCQELEKHIAVNHSEFVYPCSLCTKEFPKKDNLEEHHARVHNGIQYKKRRKMIECTLCDITFKTIKEMLEHEKQHPPNELFPCKVCPKSYRNLKLVYIHKQKHYSQRKKCPGCNKAVAVSYFKQHKALCVTLRKIEPAIICEVCGEVFHLQSSLKSHQLLHDKPEPCVHCGKKIKSASMKKHLELKHESYADQDDISIKLIQLHKCRDCGFVTRKKGEYENHRNKIHLKIKPYSCDECSRTFCVKSRLSEHMRTHSTANSCYCSFCGKKFANKVCLKMHVRRHTGESPYECNICFERFRSSSIMKTHRLKKHQDKTIACPLCDAMYHIVAEMRFHVKKTHWKSSEPFDYKKIVPEKFHHLFQDRRLTRLGDESLVITESMVGTDEYMQG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-