Basic Information

Gene Symbol
-
Assembly
GCA_947397855.1
Location
OX377612.1:11506857-11509259[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.088 5.3 7.9 2.7 1 23 425 447 425 447 0.96
2 10 0.61 37 5.3 5.4 1 23 453 475 453 475 0.98
3 10 2.2e-05 0.0013 19.2 2.4 1 23 481 503 481 503 0.98
4 10 0.0013 0.078 13.7 2.1 1 23 508 530 508 530 0.97
5 10 9.8e-07 6e-05 23.5 2.5 1 23 536 558 536 558 0.98
6 10 0.015 0.9 10.4 2.4 2 23 564 586 563 586 0.92
7 10 0.0087 0.53 11.1 1.6 1 23 600 622 600 622 0.97
8 10 9.3e-05 0.0056 17.3 1.1 1 23 632 654 632 654 0.97
9 10 7.8e-06 0.00048 20.7 0.2 2 23 661 682 660 682 0.96
10 10 0.003 0.18 12.5 2.6 1 23 687 710 687 710 0.96

Sequence Information

Coding Sequence
ATGAATTTCATGTCGAACACGGAGCCTATATCAAAAGATAATTTCAACAAATGTGGTGAATTGTACAGATCACCAATTATTAATGATAAACAGTACATATTTCTTTCGTGTATTTACTGTAAATATATTTCTTGGGAGTTTGACACCTTCTTGAAACATCTGGATAGCAGCCACCGTGTAATAAATAATATTTGTTTGAATTTATATAAAAAAGATTCTATCACAGAAGGAAACGGCCAAAGTTTAAAAAATACAAATCCTAAAATTAATTCAAATCTATCTTTAAGTAGAGAGATTGATCCTTTGGATGAAAAACATTTTGATTTTTGTGCCCTATCACCGGTAACTATTAAAGAAGAAAAGTCTGAAACGATTGAATACAAAAATGAAGCCAAAACTGAGATCGAAATCACTAGCAAAGATATCAGCGCAATAAATGAAGTTTATCAAATAAACGAATTTAAACATGACGATGGTAACAGCCTTCAAGAAGACTTTGAGCAAGATAAAATATGCATTGATGCTGATCTTAATGAAGATGAAGACGATTCTGTTGATACAAAAAATGATTTAAAACATTATGATAAAGACAATAAGAAATCAAACGTAAAGAACTTGACTAAAAATCGTGATCTTATTAAATTTATTATAAATGCTTATCGAAAACAAAACATTTTATGGGACAGTATTAATAAGACTAAAAAAATTACAACATCAGAGAAGCAGGAAGCGTTTGAAATAATATTAAAAAATATACAAGAAATTTCTAAAATTAATATATCTCGCCAACAAATAGAATATATAATAAAAAGTTTCAAATTAAGATTTGCACACTACTTGCGACACAGAGATAAAAAGGAATCATTGAAGCCTTTATGGTACTTTGAACTTTTAACATTTTTAGAACCTCATTTAAATGGAAAGAAAAAGAAGAGTGGTATATGCAAAAAATTAAACGATAGTCAACTTCTAACGTTGATTAAAATTTTAAAAGAAAATGAATGTTTCTGGAATGAAAATAATATTTACCACACTTCGATTACAAATAAACAGGAAATATTAAAACGTATAACCGAAGATTTTTTAAAAATATGTGATTTAGCAGATTTCAACTCGAATATTATGCAAAATAGTATAGATGAAATAATTGAAATGGCTAGAAAAGAGAATACCACTAAAATGCAATGCTTAGAAAATGATAAATGTGATGATTATCAAAGCAGCTGTAAATTTTATAAGGAAATAGAATTTCTACTACCACATGTTGGGCCATTTAAATGCAAATATTGTCTAAAAATATTTGTTGATATCTATACTTATAAATTTCATATATCAAGACATGACGGTACCAAGCCGTTTAAATGTATGGAATGTCCGCGAGAACTAACACATAAGAAAGAATTTGTATGTCACTTAAGGCGACATACTAAAGAATGCCCTTTTCAGTGCAACACCTGTGATAAATCGTTTCCCAGTCAAAAGGAATGGCATCGACATGTTATAAAACATGGCTCAAAGCCATATATATGCGAATTATGTGCCGATAGTTTTTATACTCAACACCAGCTAACTAATCACATGAAAAATCATAACAACATAAAAGATCATGTTTGCCCTCAATGTGGCAAAGGATTCACTCACCGTGGCTTATTAAGACAACACTTGCAGACCCATAATAAAACCAAATGTTTTTGTAACCTTTGTAATAATATATATTCGAATCCGCGTAGTTTGCGTAAACATTACGTCAGAGTACACGAGTCGAGAGACCAACAAGCAATGTCATCTAAAGCCCAGTATAATTGTCATATCTGTAAGATAACATTTGCATCAATACAAGATGCAAAGCAACACCGAAAAGAGCATAAACGGAGTAATCCCGCAGAACGCAAACATGTGTGTGACATCTGTGGTCATAATTTTGCATATCCCAGAAATTTAGCTGATCACAAGAAAATACATTCGAATATACGTGACCAAGTCTGCGATGTTTGTGGGAAAGCATTTACAAACGCCAACTTATTAAATCAGCACAAAAACGTGCATACGGGAGAGAAATTTGTGTGCAAGGCATGTGGTAAAGACTATGCACACTATCGTGGGCTATGTCGACATATCACTAAAGCTCATAGTACTAATATAAGAGATTTGGATGCTGTATTGGAAAAGCAAAAAATGTCCTCTTTGTCCTTATAG
Protein Sequence
MNFMSNTEPISKDNFNKCGELYRSPIINDKQYIFLSCIYCKYISWEFDTFLKHLDSSHRVINNICLNLYKKDSITEGNGQSLKNTNPKINSNLSLSREIDPLDEKHFDFCALSPVTIKEEKSETIEYKNEAKTEIEITSKDISAINEVYQINEFKHDDGNSLQEDFEQDKICIDADLNEDEDDSVDTKNDLKHYDKDNKKSNVKNLTKNRDLIKFIINAYRKQNILWDSINKTKKITTSEKQEAFEIILKNIQEISKINISRQQIEYIIKSFKLRFAHYLRHRDKKESLKPLWYFELLTFLEPHLNGKKKKSGICKKLNDSQLLTLIKILKENECFWNENNIYHTSITNKQEILKRITEDFLKICDLADFNSNIMQNSIDEIIEMARKENTTKMQCLENDKCDDYQSSCKFYKEIEFLLPHVGPFKCKYCLKIFVDIYTYKFHISRHDGTKPFKCMECPRELTHKKEFVCHLRRHTKECPFQCNTCDKSFPSQKEWHRHVIKHGSKPYICELCADSFYTQHQLTNHMKNHNNIKDHVCPQCGKGFTHRGLLRQHLQTHNKTKCFCNLCNNIYSNPRSLRKHYVRVHESRDQQAMSSKAQYNCHICKITFASIQDAKQHRKEHKRSNPAERKHVCDICGHNFAYPRNLADHKKIHSNIRDQVCDVCGKAFTNANLLNQHKNVHTGEKFVCKACGKDYAHYRGLCRHITKAHSTNIRDLDAVLEKQKMSSLSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-