Basic Information

Gene Symbol
hang
Assembly
GCA_937641085.1
Location
CALMRH010000055.1:802206-809906[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.046 6.8 8.1 1.3 3 23 330 351 329 351 0.93
2 19 0.35 52 5.4 4.5 2 22 449 469 448 469 0.93
3 19 0.018 2.7 9.4 2.4 1 23 544 567 544 567 0.91
4 19 0.55 81 4.7 0.1 2 21 579 598 579 599 0.93
5 19 2.7 4e+02 2.6 1.7 2 22 607 627 606 629 0.87
6 19 0.00094 0.14 13.4 0.2 3 23 703 724 702 724 0.96
7 19 2.2e-05 0.0032 18.6 0.2 1 23 732 755 732 755 0.98
8 19 9.8e-05 0.014 16.6 0.1 2 23 860 881 859 881 0.97
9 19 6.1e-05 0.009 17.2 2.6 2 23 949 971 948 971 0.93
10 19 0.0032 0.47 11.8 0.2 2 23 980 1002 979 1002 0.95
11 19 0.00044 0.065 14.5 0.2 1 23 1015 1038 1015 1038 0.97
12 19 9.9e-05 0.015 16.5 1.1 1 23 1099 1121 1099 1121 0.99
13 19 0.0015 0.23 12.8 0.9 1 23 1129 1152 1129 1152 0.96
14 19 0.048 7.1 8.1 0.1 2 20 1160 1178 1159 1178 0.95
15 19 8.6e-06 0.0013 19.9 0.5 3 23 1251 1271 1250 1271 0.98
16 19 3.3e-05 0.0049 18.0 0.6 1 23 1306 1328 1306 1328 0.97
17 19 0.0001 0.015 16.5 0.5 2 23 1405 1427 1404 1427 0.92
18 19 0.003 0.44 11.9 0.7 3 23 1482 1502 1482 1502 0.99
19 19 0.00098 0.14 13.4 0.3 1 23 1737 1759 1737 1759 0.98

Sequence Information

Coding Sequence
ATGGTCGGTCGAATTCGCAGTAGCCAAACCACAGCATTATTAACACTAAATTTGGTGACACCCAACGACGGGTTGTCCTTACGCATCTGTCACGCTTGTATTAGCTACTTGAACTCCTGGCAAAGCTTTAAAAATCGTTGCGTCTCTGCTCAAAATAAGCAATTGAATTTAATCGAGCACGTGAAAAGGCAACAATTGACGGGAAATAATGTCAGCATTACTACAGTATCGGAGGCAGCTGGATACACAACACCAAATCAGCAGAAACATCAACAGGATCAGCAGGACAATCATCAATATTCGTCGCAGGAATCGAATGCGACGTCTTCTCTTTTGGAAGGCATCACATCGCTAAAGAAGCGCAAATCGTTGACAGTCTATGTGAGTCCAAAACAACATAAAATTCCACAAGAACAATCGCCAAAGCAACAACAATTGCATCAAAAACGACCAAAGCAGCCGCCGTCGCAGCAGATGCAGCATGTTTCACATGCGCCGCTGCTGTCTCTGCCGCCTCTGCAACCTCAGCCACATTTAATGCAGTTGAAAGATTTAGAATCACAAAATAAACATCAGTCTCAGATGCAAAAGTCGCATCAGCAGGAACAAAATCAAGCAGAAGAACTTCAACCGCCTTCTCAGCCACTTCAGCAGCATCAACAGCAAGAATTAAATCTTGCAACTGCTACGCAACAATTACGTTACTTTAGACGTTGCTCTTACAATCCTTTGCCGGCGGTTCAGGTGAAAGACGAGCCTATGGATGAGGAGGATTATGAGAGCATGAAGCAACAGCCAGACGAATCCGATGAAATGGTAGATCCTACGCTCTTCCTTGAGCGGAACGAAGAGGAAGTTGGTGAACCGTACATGACGCACGTCCATTCATCCATCCAAGACGTGAGTAACTACAGCTATGAGTTGCCGCAGTCTGTACCGGACCGTACAACCATTGAAGTGGCTGCCGCCGAGGTGAAGGAAGCCTCTTGTCGCGCTTGTAACTTAAAGTTCTCCACCCGAGCAAATGCTCGACGTCACGAACGCAATCTGCATCCGAATCTTTTCGAATTGTCCACTACAACACCGAATTCAACGCCCATTACCAAGCCAACTGCTGCCTTAGCAGCCGCATTGGAATTGCAACGTGCTGCAGTTGTCGCTGGCGATATGGCCAAGAAGTCATTTGCCGCCCTTAACATCACCTCGGGCGCCATGACACAGCGCAACAAATTAGACGCAAACTTTGACTATGAGAATCCTGAACGATATCAAGATCTCTTGACCGATGAGAAGATTGTTTTCATACAGCAAAATGAGGAATTCCTCCAGCAGTACCAGACCATGACATGCAAATGTTGTCGCAAATTTTACACTAGCTACAAGAACTTCATGGCGCACATGCGTAAAAAGTACGTGACGCTGCCGCGCAACGTTTGCTTCAATTGCCTGAAACTGAATGACTCGAAGGCACTCTTCATATCGCATCTTAAGAAACGCAACTGCATCAATCTGTACAAAGTTATGCACAGTCTCATCGCTCGCGTTCCGAGCTTTGCTGCTGCCGTCGCAGGCACCGCTGCTGCCATGCCAGAAAAAATGCGCGCCAAGGAATTGCTGGTCAATAAGATTTATGAGTGCAAATTGTGCCCGAAACACTTCCGTTTAAAGTTGGAATTTCGCACGCATGTGTACGAGGAGCACGGCGATGCTCAGAAGAAGGATTTGTCACCGGGTCAATGCGGCTTCTGCGGTTTGGAGTTTGAAGATCCCTTGGAGCGCAAGCGTCATTACAATAACATGGATTGCATCGTCATCCTGCGCTGTGTCACTTGCAATGAGAAGTTCGGCAATCATCAGAAATTCTTAGATCACGTTTATGCTAAACACTTGGTACAATCGGCCAACAGCGCTTTGGTCGACCGTCAGCGTCAGCTGCACCAAACTTCGTCCCATTCTAACGTCGGCATTTCAGATAATTCACCTGGGAAAAAGTCAAATACAGGAGGATTTGGAGGACCCACTTCATCGGCCGATGAATCGCGAGGAAGCAGCGTTCAGCAGCATGCTGCTGCCAAGTCTCAATACTTTTCGCGTATGCCACAAGCCTGTCCGATTTGCGGCCAACAGTACAACAACTACAACAACGTTTTACGACACATGGAATCGAAACATCCCGATCAGCTACCGCAAACCTACAAATGCGTCAAATGCGGCAATGGATATCCTCGTCTATCGAATCTCAGGGAGCACATGCTAACAGTGCATTCAGGAGCGGCAATGAGCGAAAAGGCACGCAGCACCAGCTTCGAATACATCGTGAATGCAGACGCTGTGAAATCGATGGAGAGTGGCGGAACAGGAAGTGGTGGAACAGGCGTTAGCGGTGCATACAGTGGACGTTATGACTACGTGATGAAAGACCTGATGTCGATTACAAATGGCGGCGCTGTCGCTGATGATGACGATGATGATGAGGAGGGGGGCGGCAGCGCTCATGTGGCCAAGAAAATGCGCTTAGACAACAGTACCAACAACGCCTCCTCCTCCGGAAATTCGAATGCTTTAAGTCATTATAAAGAGTGCCCCATCTGTAGCGCCATCTTTAGCAATAACATCGGCCTTTCTAACCATATGCGTTCTCATACTGCTGGGCAACATAACTTTTCGGGCATTGGCTCCAGCTTTAGAGATCAATCAGGCAAGTTTAGCGCCGATAAGTCAACAGCCGGCGGTGGCACGAATACTGCTGCTGCTGGATCCTCGTTATCTATGCAACAAAAGACGTCGGCACAAATGTTTAAACGTAGCCTAGAGCTGGCTGCTGATCGTCGTTTCCGGCGCATGCGCTGCCGCATCTGTCAGAAGCGATTCTCGTCGAAGAAGTCGTATCGACGTCATATGCTCGATGAGCATCAGATCACCAACGTCCAGTTCATCAAGTGCAAACTGTGCGATGCCGAGTTCGCTTACGAGAAAGGTCTGAAGGTGCATATGTTTAAGATTCACAACACATTGTTGAAGAATGAGATGATTATCAAGCAGTTCGAGTGCGACATTTGCTCGATTGTCTATCGCACCGAGGATCAGTTATTGCAGCATAAGAATTCAGTTCACGGCAACGAACACGCTCACCCGGATGATTTCGTAGACAAGGGCAACAACAGTTCTATGGGCGGAGCAAGTGGCAATAATAACAACGGCAGACGTGCCGCCTCCGCAGACGTGTCCGCCGCTAACCTGTCCAGCACGTCGCAGGGGGATCCGATCGTGCATTTGTCTGCTCCTCTCTACTGGTACCAATGCAAATATTGTCCCTCCAACTTCAACACGAACAAGAAACTAGCGATTCACATCAATTCACACGACGAATTCGATTCCAGCGATTATTCGTGCAAGGACTGCGGTAATGTGTACAGCGGACGGAAAAGTTTGTGGGTTCATCGCTACAAGAAGCATCCACAAATTGCGGAACCCTCGGAGTGCGTACTCTGCCGCAAAGTATTCTTCGACAGCCAAATGTTGGAGAACCATATTCCGACTTGTAATCGTAAGCCAATCACTGCAACCGGAGCAATTGCCGATCAGTCGACACCGGGCAACAGTTTCTATCGTCACAAGACGGGCGACGATGAAGACGATGACGGCAGCCGCCCCGGAGCCGAGAATGCCGAGGAGAATGCTGATGCTTTGACTGGCGGCGGCGGCGGCGATGGAGAACTCAAACTTAAAATCAAATTACCTGAAGTGGCTTGCACGATGTGCGGACAGCGTTTCACCGACCAAGACCTATTCACGAAGCACATCCAAGTGCATGAAATGGAGCTGTACACGGATAATCCTCTGGCCGCCATGTTCGATACTGGGCCCGCCGATCCCAACCAATTCTACTTGGATCGAGTGAATGACAACGGGGAATATGCGTGCGACATCTGCACGAAAACCTTCACTCAGATGACTGCGTTGAAGGTGCATCGTAAATGGCATTTCAGAGGTGATAGCAAACAGGACTTTGATGTACCATATTTTGAAATTTTACTAACCTTTGCGCCTCATCTCCACACACAGCAGCAGCAGAACCAACAATCCGACGCCGATCCTTCAGCATTTGTGACCTCACAGACCCCCAACCTTCTACATCCACCGGGATTACAAGCAGTCGGCCTCATGCCGAATCCACGCCCTTCCAAGCCGATGAAACGCAAGCGCGAACTTAAGTGCGAGTACTGTCCGTCGACCTTCATCAGCAACAACAACCTGCGTCGCCACATCTATGAGCTGCACAAGTCGGAAATCGCTCATTGGCCGGAGCCGCCGAAAATCAAGCTCGACGATTATCTGCAGTGCCGGAAATGTGCCCTTAAGTTCGAATCGAAGAAGGTGTGGATCGATCACAAGGTGGCCGATGCACGAATAATGAAGCCCTACGGCCCCTTCCAGTGGGGCTGCGAGTTGTGCGGCGAGTATGTGTCACGCAAGGAGAAACTGATTCATCATATCCAGTCGCACATGAAGGAGCAggtggtgctgccagtgcagcagaggcgccagcaggaagcggtagcagcagccgcagcagcagcagctgaggcgcaaaatgatagaaatgctagagacggggaaagcgacggcggaggtgactcgcaacactctcgtcacaatgaggaaaacggcggcgaatacgatggtggcgatggaacagctaaagacgaggactacgaaggagatgatggactggactatgttggggatgatgacgaggatcaagagcaggaggaggaggaagacgatgacaatgaagaggatgatgacgatgacgacggcggagttgatgttaacgataatgaagcaatgaataaaactggcaaatctttacatgaaattggaggacctgaagaggcaaacgatgacgatgacgacaacattgagaatattgatgaaaatgcaaacgacgggcagcatggcaatgatgacgacttggatgacgatgtagacgaggaggaagatgagggcgacgatgatgacgacgtggacgacgatgatgatgacgacggggaagacgatgatgatgatgatggagagcttgagattagcagacgcttaatacgcgaccacgattatattgaggttgacgttgataatgaagaaatggatgatgaaaacggagacgaggccggcatagaagatgcagaactgaaaccgAAAGCTCGATTCCCTTGCGATCTCTGCCAGGTATTTTTCGACACGCAGCTGGAGCTGCAGAAACATGTGAAAATACATTTTTTGAATGGGCCTGGATCAGTCACTCTCACCGAAATCCGAGCCAAGCAAGGCAACAAAAGCCGCAACGGCGTCAATAACGACGCTACGTCGGCCTCATCACCATAA
Protein Sequence
MVGRIRSSQTTALLTLNLVTPNDGLSLRICHACISYLNSWQSFKNRCVSAQNKQLNLIEHVKRQQLTGNNVSITTVSEAAGYTTPNQQKHQQDQQDNHQYSSQESNATSSLLEGITSLKKRKSLTVYVSPKQHKIPQEQSPKQQQLHQKRPKQPPSQQMQHVSHAPLLSLPPLQPQPHLMQLKDLESQNKHQSQMQKSHQQEQNQAEELQPPSQPLQQHQQQELNLATATQQLRYFRRCSYNPLPAVQVKDEPMDEEDYESMKQQPDESDEMVDPTLFLERNEEEVGEPYMTHVHSSIQDVSNYSYELPQSVPDRTTIEVAAAEVKEASCRACNLKFSTRANARRHERNLHPNLFELSTTTPNSTPITKPTAALAAALELQRAAVVAGDMAKKSFAALNITSGAMTQRNKLDANFDYENPERYQDLLTDEKIVFIQQNEEFLQQYQTMTCKCCRKFYTSYKNFMAHMRKKYVTLPRNVCFNCLKLNDSKALFISHLKKRNCINLYKVMHSLIARVPSFAAAVAGTAAAMPEKMRAKELLVNKIYECKLCPKHFRLKLEFRTHVYEEHGDAQKKDLSPGQCGFCGLEFEDPLERKRHYNNMDCIVILRCVTCNEKFGNHQKFLDHVYAKHLVQSANSALVDRQRQLHQTSSHSNVGISDNSPGKKSNTGGFGGPTSSADESRGSSVQQHAAAKSQYFSRMPQACPICGQQYNNYNNVLRHMESKHPDQLPQTYKCVKCGNGYPRLSNLREHMLTVHSGAAMSEKARSTSFEYIVNADAVKSMESGGTGSGGTGVSGAYSGRYDYVMKDLMSITNGGAVADDDDDDEEGGGSAHVAKKMRLDNSTNNASSSGNSNALSHYKECPICSAIFSNNIGLSNHMRSHTAGQHNFSGIGSSFRDQSGKFSADKSTAGGGTNTAAAGSSLSMQQKTSAQMFKRSLELAADRRFRRMRCRICQKRFSSKKSYRRHMLDEHQITNVQFIKCKLCDAEFAYEKGLKVHMFKIHNTLLKNEMIIKQFECDICSIVYRTEDQLLQHKNSVHGNEHAHPDDFVDKGNNSSMGGASGNNNNGRRAASADVSAANLSSTSQGDPIVHLSAPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSSDYSCKDCGNVYSGRKSLWVHRYKKHPQIAEPSECVLCRKVFFDSQMLENHIPTCNRKPITATGAIADQSTPGNSFYRHKTGDDEDDDGSRPGAENAEENADALTGGGGGDGELKLKIKLPEVACTMCGQRFTDQDLFTKHIQVHEMELYTDNPLAAMFDTGPADPNQFYLDRVNDNGEYACDICTKTFTQMTALKVHRKWHFRGDSKQDFDVPYFEILLTFAPHLHTQQQQNQQSDADPSAFVTSQTPNLLHPPGLQAVGLMPNPRPSKPMKRKRELKCEYCPSTFISNNNLRRHIYELHKSEIAHWPEPPKIKLDDYLQCRKCALKFESKKVWIDHKVADARIMKPYGPFQWGCELCGEYVSRKEKLIHHIQSHMKEQVVLPVQQRRQQEAVAAAAAAAAEAQNDRNARDGESDGGGDSQHSRHNEENGGEYDGGDGTAKDEDYEGDDGLDYVGDDDEDQEQEEEEDDDNEEDDDDDDGGVDVNDNEAMNKTGKSLHEIGGPEEANDDDDDNIENIDENANDGQHGNDDDLDDDVDEEEDEGDDDDDVDDDDDDDGEDDDDDDGELEISRRLIRDHDYIEVDVDNEEMDDENGDEAGIEDAELKPKARFPCDLCQVFFDTQLELQKHVKIHFLNGPGSVTLTEIRAKQGNKSRNGVNNDATSASSP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-