Basic Information

Gene Symbol
-
Assembly
GCA_017165845.1
Location
WUAW01012201.1:47439-62559[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.099 9.1 7.6 4.0 1 23 244 267 244 267 0.92
2 26 2.3 2.1e+02 3.3 0.3 5 23 299 318 292 318 0.86
3 26 0.0046 0.43 11.8 0.8 1 23 340 362 340 362 0.97
4 26 0.3 27 6.1 1.3 1 21 366 386 366 388 0.76
5 26 0.083 7.6 7.9 3.0 1 23 392 415 392 415 0.96
6 26 0.17 15 6.9 5.2 1 23 421 444 421 444 0.96
7 26 0.004 0.37 12.0 0.5 1 23 451 474 451 474 0.94
8 26 0.0026 0.24 12.6 4.6 1 23 480 502 480 502 0.98
9 26 1.7e-06 0.00016 22.6 1.1 1 23 508 530 508 530 0.98
10 26 0.0044 0.41 11.9 1.1 1 23 536 558 536 559 0.96
11 26 0.41 38 5.7 2.0 1 23 602 624 602 624 0.95
12 26 0.54 50 5.3 0.0 3 23 654 675 652 675 0.94
13 26 0.23 21 6.5 0.3 2 23 696 718 695 718 0.95
14 26 0.00083 0.077 14.2 2.1 2 23 724 746 723 746 0.95
15 26 0.0033 0.3 12.3 1.0 1 23 751 774 751 774 0.94
16 26 0.96 89 4.5 0.1 2 23 777 799 776 799 0.92
17 26 0.052 4.9 8.5 1.7 2 21 806 825 805 826 0.93
18 26 0.0069 0.64 11.3 0.4 1 23 885 908 885 908 0.93
19 26 0.2 19 6.7 0.1 3 23 937 958 935 958 0.91
20 26 0.088 8.2 7.8 0.2 3 23 982 1004 980 1004 0.94
21 26 0.00076 0.07 14.3 0.6 3 20 1011 1028 1009 1032 0.90
22 26 0.008 0.74 11.1 0.2 1 23 1037 1060 1037 1060 0.97
23 26 0.0026 0.24 12.6 0.5 2 23 1066 1088 1066 1088 0.94
24 26 5.3e-05 0.0049 17.9 4.9 1 23 1092 1115 1092 1115 0.97
25 26 0.00024 0.022 15.9 0.6 2 23 1122 1143 1121 1143 0.96
26 26 0.0038 0.35 12.1 2.3 1 23 1149 1171 1149 1171 0.97

Sequence Information

Coding Sequence
ATGGAGTTCAATGAAATCGTGGTTAAAGAAAGCCCTGGGCTCTGCAGGTGCTGTCTTTCTGAAGGCTGCTACAAAGACTTGGGATCAGAGTATAATTGGATGAATGAAACTGAAATATATGCTGATATGTTGTTAGAATGTTTTGACATTAGCATAACACAACACAACGAAGGACCAAATGGACCTAATCGGCTTATCTGCGAAGTGTGCATTACGCGGCTACGAGATGCGTGCAATTTTAAGAAGCAAGTTCTTGACTCCGAAAAGAAGTTTATTGATATGGTTGCCCGGGGAGAGTTTAAGCCTAAGATGCTGGTATATCAGGCCAACATGAAAGCTGAGGATACCTTAGAGGCCCCTTCTGAAGATGGTGATGGTGAGGTGGAGTTTCTTGAGGAAGAGATAAACTTTGGAGATGATGAAACGGTAAAAGATGAATCGGAGGAACCGTCAGCGTCCAATATAACGGTCACCACACTGCCTATAAAATCCAAACGTGGAAGACCACCAAAGACCAGTGCCCTCATAAAGCCAGAGAAGAAAATCAAAGTTGCCAAATTTGAGGATAAACCCAGGACCTCGAAAGCAGTCCCCAAAGGTGTGACATCGGCAGAGGCAGCGAGTAAGTCCTCTATATCATCCACAAAACGCAACAGACAAATGAAGAAGAACGCTATAGCTATTATAGAATCATCCACAGCAGTACCCTTTAAGTGGCACAGACAAAACTATCTTTGTTTCTTCTGCCACTTgacatttaaaactataactagCCTTAAAGAACATACTAAAGACACACATgctaattcaaatataaaagcTGCTGTATCAATATTAAGAAGGGATGAAAAGGTCAAAATAGATGTCACAGAGTTAGAATGTCGTAATTCGTCGTTTTGTAGAGCAAAATTCGAAGATATTCCATCGTTAATAGATCATTTAAAGACTCGTCACGATAAAGTATTCAATGAGGAGTACGATTATGGTGTTATACCGTACGTGATCGAGAATGATATGTTCTACTGTGCAATTTGTAAAGAAGTATTCCAGTATTTTATCAAACTAAATCAACATATGAACGAACATTACGGTACTTATATATGCGAGCTATGTGGAAAGACGTTTCTAAGTCAGGAGCGGTTGCGATGTCACGGCCTTTCGCACAATTCAAGTCACAAATGCATGTATTGCACAGAATCATTTCCGTCAACCACTTCAAGGAACAATCACATTTACAAAGTGCACGACATTAAAAAGTTACACAAATGTTTCTACTGTCCGGAAACCTTTGAAAATTTCAATCAAAGGAAGAGCCATCATAATGTCGTACATAATGTGGCAATAACTGAGTTCAACTGTCCAATATGCGATAAGAAATTTCAAATAATGAGCAAAATGAAGATACACTTGAAGGAAGTGCACGATAGGGAGAGGAATTACTCTTGCACTATGTGCGATCTGAAGTTCTTTTCGAGGACTCACGTTAGGAAGCACATGGTGAAGCATTTAGGTGATAGGATATACAATTGCGAGGTTTGCAAGAAGTCATATCCGAGAAAGCAGAGTTTAAGGGACCATATGAGGATCCacaataaagataaaagatTCGTGTGCTCCGTGTGTAGTGCCGCGTTCGTTCAAGGTCACAGTTTGAAATTGCACGTGAAGGTGCATCATTCGGAGTCGCAgaGTCTAAAATCGAGGATATACAAAGGCAGCGAATCGTCGTCCATGCGCCGACGACGAAATCTACAGATTTTATTCAACAACACGTCGATAATACCTTTTAAATGGCGCGGGAAGTATTTGTGTTTCTTTTGTAGCAAAGATATTAGTGAATATACCGAGTTGCGGAAGCACACGAAGTCTCATGGTAAATGTTCCACCAGGGACCATTCCCTTAAGGTATTGAAAGGTGGACAAAACATGGAAATCAAAATTGATGTTTCTGATATAAATTGCGAAGTTTGCTCGGAACCTTTCCCGGTTTTCGACGAAGTGGTCAATCatttattgatgaaacataagtTAGAGTATGATCGAGGAGTCGAAATGGCTATAGAAGAGTATAAACTTGTAGACCTCAGCTGTTTGGTTTGTCTTCAGAAGTTTTCTTACTTTGGATACCTGGTGTCTCACGTAAACAGCAACCATCCAAAAAAATGTCTCATTTGCGATAAATGTAAccaaaaattcaacaaaaaaaggGATTTGTTCTCTCATATCAAAAATTACCATCGCGAAGGGGGATACCAATGCGAAGTGTGTCCGCAAACATTCAGTTCACTCAATATCCTGAGAAAACATCGTACCAATCGACACCTCACTAGATGTAACATTTGTCAACTGAAATTACCTTCAGCTGCTTTGAAACAGAAGCACATCGATTTGGAGCATCCGGACGATGGCTCTTTGCAAtgtgataattgttttaaaGATTTCCACACAAAGCAAGGTCTTAGAATGCATGAAAGAAAGTGCAAAGGCGAAGATGTCTTCGAAATTGCTATCAAAAAAGAAGACTATGTGTCGATGGATTTAGATCAGACGTACGAGGAAATAAAGAGGCCTAGCGTTAAACAGATCAGAGAAAACATCGTTATAGTCATTAATATGTCAACTGCGATACCTTTTaacttctataaaaataaattcaattgtttttattgcTCTAAAGATTTCCCCGATTCGGATTTGATGAGGGAACACACAATTTTGGAACATCCAACTTGTGATGTTAAACAAAAATGCATCAGAAAATGCAGGGAATCTGTCGCGTGCGTCAAAATCGACGTGTCCACTTTAGCTTGCAAAATTTGCTTTGAATCTATGTCCGATTTGGACAATCTGCTCGACCATTTAATAGCGAAACATAATGCGACttatgataaaactattacaacaTGTTTACAGCCTTATCGGCTTATAAAGGACCATATGGCTTGCCCAAATTGTCCAGGAGAGGCGTTTAGGTTCTTCGGGACTTTGCTCAAACATATGAACAAGAAACATACTAATAATAACATCATATGCGTTTATTGTGGCCAGACATTTCGTAGGGATCAAAATTTAAGAGTCCACATCTGGAGGCATCACAGAGATGGACGCttcaaatgtaatatatgtGGAGCTGAATGTAATATACCCTCCAGATTGTACGTGCACATGGCTAGTGCGCACGGTGTGAAAGCAGCCAAGTGCACGAAATGCCCAGAAAGATTTGCAACTCAATATTTGAGGCAGAAACATTTAATAGAGGCTCACGATTCAGGACACAAGTGTACTTATTGTGGCAAATTGTTCACTAGAAACTCGTTCATGAGGGACCACATAAGAAGGACCCATTTGAAAGAGAAGAACGTAGAATGTTCTATATGCAATATGAAATTCTTTAACAATATTCTTCTGAGGCGGCACATGGTTAAGCATAGCGGCGAGAAGAACTTCCATTGTGATATTTGTGGGGAACGATTCTTTTGGAGGAAAAGCCTTAGGACTCATATGGCTAGGCATAATAGACATCTTGGCATCGTCCAAGTGTAG
Protein Sequence
MEFNEIVVKESPGLCRCCLSEGCYKDLGSEYNWMNETEIYADMLLECFDISITQHNEGPNGPNRLICEVCITRLRDACNFKKQVLDSEKKFIDMVARGEFKPKMLVYQANMKAEDTLEAPSEDGDGEVEFLEEEINFGDDETVKDESEEPSASNITVTTLPIKSKRGRPPKTSALIKPEKKIKVAKFEDKPRTSKAVPKGVTSAEAASKSSISSTKRNRQMKKNAIAIIESSTAVPFKWHRQNYLCFFCHLTFKTITSLKEHTKDTHANSNIKAAVSILRRDEKVKIDVTELECRNSSFCRAKFEDIPSLIDHLKTRHDKVFNEEYDYGVIPYVIENDMFYCAICKEVFQYFIKLNQHMNEHYGTYICELCGKTFLSQERLRCHGLSHNSSHKCMYCTESFPSTTSRNNHIYKVHDIKKLHKCFYCPETFENFNQRKSHHNVVHNVAITEFNCPICDKKFQIMSKMKIHLKEVHDRERNYSCTMCDLKFFSRTHVRKHMVKHLGDRIYNCEVCKKSYPRKQSLRDHMRIHNKDKRFVCSVCSAAFVQGHSLKLHVKVHHSESQSLKSRIYKGSESSSMRRRRNLQILFNNTSIIPFKWRGKYLCFFCSKDISEYTELRKHTKSHGKCSTRDHSLKVLKGGQNMEIKIDVSDINCEVCSEPFPVFDEVVNHLLMKHKLEYDRGVEMAIEEYKLVDLSCLVCLQKFSYFGYLVSHVNSNHPKKCLICDKCNQKFNKKRDLFSHIKNYHREGGYQCEVCPQTFSSLNILRKHRTNRHLTRCNICQLKLPSAALKQKHIDLEHPDDGSLQCDNCFKDFHTKQGLRMHERKCKGEDVFEIAIKKEDYVSMDLDQTYEEIKRPSVKQIRENIVIVINMSTAIPFNFYKNKFNCFYCSKDFPDSDLMREHTILEHPTCDVKQKCIRKCRESVACVKIDVSTLACKICFESMSDLDNLLDHLIAKHNATYDKTITTCLQPYRLIKDHMACPNCPGEAFRFFGTLLKHMNKKHTNNNIICVYCGQTFRRDQNLRVHIWRHHRDGRFKCNICGAECNIPSRLYVHMASAHGVKAAKCTKCPERFATQYLRQKHLIEAHDSGHKCTYCGKLFTRNSFMRDHIRRTHLKEKNVECSICNMKFFNNILLRRHMVKHSGEKNFHCDICGERFFWRKSLRTHMARHNRHLGIVQV*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-