Basic Information

Insect: Tetragonisca angustula
Gene Symbol: mecom-b
Assembly: GCA_036937485.2
Location: JAWNGG010000219.1:11844-25286[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0072 0.7 10.9 0.3 2 23 133 155 132 155 0.94

2 9 0.54 52 5.0 0.1 1 23 162 185 162 185 0.93

3 9 1.6e-05 0.0016 19.3 1.7 1 23 191 218 191 219 0.93

4 9 4.6e-06 0.00045 21.0 2.6 1 23 225 247 225 247 0.95

5 9 2.8e-05 0.0027 18.5 5.0 1 23 253 275 253 275 0.99

6 9 0.00056 0.054 14.4 0.7 2 21 283 302 282 303 0.95

7 9 6.6e-09 6.4e-07 29.9 1.2 1 23 654 676 654 676 0.99

8 9 3.4e-07 3.4e-05 24.5 1.7 1 23 682 705 682 705 0.97

9 9 9.7e-06 0.00095 19.9 3.4 1 23 711 733 711 733 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0072	0.7	10.9	0.3	2	23	133	155	132	155	0.94
2	9	0.54	52	5.0	0.1	1	23	162	185	162	185	0.93
3	9	1.6e-05	0.0016	19.3	1.7	1	23	191	218	191	219	0.93
4	9	4.6e-06	0.00045	21.0	2.6	1	23	225	247	225	247	0.95
5	9	2.8e-05	0.0027	18.5	5.0	1	23	253	275	253	275	0.99
6	9	0.00056	0.054	14.4	0.7	2	21	283	302	282	303	0.95
7	9	6.6e-09	6.4e-07	29.9	1.2	1	23	654	676	654	676	0.99
8	9	3.4e-07	3.4e-05	24.5	1.7	1	23	682	705	682	705	0.97
9	9	9.7e-06	0.00095	19.9	3.4	1	23	711	733	711	733	0.99

Sequence Information

Coding Sequence: ATGCTGGAGCGACAAGTAACACTGGGTGATGAGAGGGCAATATCCGTGAGCGGCAGTCCGTTAAACGCAACGCCCCGGgTTCGTACAGCTGGAAGTGGAGTAAGGGGGTGGTTGGACGCTTCtcacgaaacgaataattgGTTGAAGTATATTCGAAGCACTAGCAGTCCGCACGCCGTTAATATGCGACACGTGCTTATTGGTGGACAGATGGTGTACGAGGCGGTGCGAGACATAGCGGCCGGTGAAGAGCTGTTTCTCGGTGTTCGAGAACCTCTTCAATTGCAGGATATGTTTGGCGAGAATACTACAGAAGACAGAAGCGATCGAGAGACCGCCTCGCAACATAGTGGCACCGTAGACGAGGATAAAGAGGACGAGGAGGAAGGTGAGACCAGGTGTCCGGTCTGCGACAAACCGTTCCAAGACATTGAACTGTTGGATAGTCACGTGGTTACCTGTCACAGATACCCAGCGGAACAGCATCGTTGCGACAGCTGTCCTCGTGCATACGCCTGGCGGCCACTGCTGGTTCGTCATCGTGCGATAGTTCACGGTGATCTCCGGAACTACCCCTGCGAAAACTGTCCAAAGTCGGACAAACCGCAGGTCTTCACGGACCCGTCGAACCTGCAGCGACACATTAGGACCCATCACGTGGGCGCGAGGAGTCACGCGTGCACTGAGTGCGGAAAGACGTTCGCCACCAGTTCCGGCCTTAAGCAGCACACCCATATCCACAGCAGCGTGAAGCCGTTCCAGTGCGAGGTGTGCTTCAAAGCGTACACTCAGTTCTCAAACTTATGCCGACACAAACGCATGCACGCGGATTGCCGTATGCAGATCAAGTGCGTTAAATGCGGACAGTCGTTCAGTACGGTCACTTCGTTATCAAAGCATAAGCGATTCTGCGATTCAACGCCGCCAACCGGTCCACCTGGCGCGATGCCGCAATTACCGACACCGGCGCCTAGCCCATTTCTCGTCTATCCTAGACCTCCCGTTAGTCTCCCGGGAGGCTTGCCTTTCTATCCGCCTAGTCTAATGGGGCCGTATCCAGGAATTTTTCCAAATGCGTCCAATTTCTTGAACACTCCTTTGCTGTTTCCTCCAAAAATCGAGGAAGCTGAGAAGAGATGCGACAGTCCAAAGAAAGAACGCTTCACTCCGCCGAGGGTTCTACCGCAACATAGCAAGATATCACCTTCAACAGCCGAGGAAGCTACATCTTCCTTCAGACCATCCCCGGCTAGACCACCCGTTCAACCAACCCCGGAGAGCGACGACGATCCTTccaagaaacgagagaaagacagaagcAACGAGAAGAAGGCGGATTCTGAAAACGTATCGAAAACTACGAACGAAGAGACAACGGATCAGCCTTTGGACCTGAGAGTGCAAACAAAGAAACAACGGACGAACGTGAACGTTACCAACAGAAAGAGCCCATCGCCAACACCAGCACCGATGGAGGAAGTTCCAGCTCCTCTGGATCCTCCAAAACCAGAGGAAGAGACGTCCATGCTGATGGAAGTCGATTCCAAGGACGTGGCAAGAAGTcctcaattaaaaattagtttacCCGCAGAACAACCGCCTACTAGTACACCGCACATGGCGTATCCCAGACCGATTCATCCAATGTTTCTGGAGGCCATGTACCGCGGACCAACGAGTTCCTTTCCAGGATTTCCAGGCGGACCACCGCCTCCTGGAAGCGGAACAGAACCGAGACTCTTGCCACCACTACCACCGTTCGGGACACCGCGTGGACTTCCTTTTTTAGGAACACTCATGAACGGGCTCAGCGGCGCTAGGCCAGGAAGCGGAGGATTCGACTTGCTTGCCAGGCCGCCACTGGGACCGTTCCCCGGCGTGAAACCCTTTCAGGACGCCGTGATTCCACCTCACCatcatcaccatcaccatcacgCTCACGGCAAAATGAAAGATCGATATTCCTGCAAGTTCTGCGGCAAGGTATTCCCCAGATCCGCCAATTTGACAAGACATTTACGCACACACACCGGCGAACAACCTTACAAATGCAAGTACTGCGAACGGTCCTTCAGCATCTCTAGTAACCTTCAACGGCACGTAAGAAATATCCACGACAAGCAGAGACCGTTCAAGTGTCCACTCTGCGAGAGATGTTTTGGCCAACAGACGAATTTGGACAGACATTTGAAGAAACACGAAGCCGACGACGGCAGTGGCGTTGTTTCCGTGGCGGATTCACCGGGGAGCAGCAATGAAAATGAACGGGAGGACACGTATTTTGACGAAATTAGGTCGTTCATGGGGAAGGTGACTTACGGCGGTGAGGCTGGCTACGGATTACCCCCTCACCCGGCCTATTTGCCCAGTAGACTTCACGAGATTCACGAGTCCAAGATGGAAACGGAGTATGACGAAGACGAGGATAGCGAGGAAGGAGTTTCTCCTTTGGATGAAGCGGATGGCTTATCGCCAGCAGAAGCCAAAGAATCGACTCCACCACCGCAGTATGATCTGAAGCTGAGAGAGAAGCAGGAATTGCTTAACAATAACACGGCCGAGCCAGTTATCGAGATTTCGACATAG
Protein Sequence: MLERQVTLGDERAISVSGSPLNATPRVRTAGSGVRGWLDASHETNNWLKYIRSTSSPHAVNMRHVLIGGQMVYEAVRDIAAGEELFLGVREPLQLQDMFGENTTEDRSDRETASQHSGTVDEDKEDEEEGETRCPVCDKPFQDIELLDSHVVTCHRYPAEQHRCDSCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSDKPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTPPTGPPGAMPQLPTPAPSPFLVYPRPPVSLPGGLPFYPPSLMGPYPGIFPNASNFLNTPLLFPPKIEEAEKRCDSPKKERFTPPRVLPQHSKISPSTAEEATSSFRPSPARPPVQPTPESDDDPSKKREKDRSNEKKADSENVSKTTNEETTDQPLDLRVQTKKQRTNVNVTNRKSPSPTPAPMEEVPAPLDPPKPEEETSMLMEVDSKDVARSPQLKISLPAEQPPTSTPHMAYPRPIHPMFLEAMYRGPTSSFPGFPGGPPPPGSGTEPRLLPPLPPFGTPRGLPFLGTLMNGLSGARPGSGGFDLLARPPLGPFPGVKPFQDAVIPPHHHHHHHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPPHPAYLPSRLHEIHESKMETEYDEDEDSEEGVSPLDEADGLSPAEAKESTPPPQYDLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539779;
90% Identity: iTF_00118172;
80% Identity: -