Basic Information

Gene Symbol
-
Assembly
GCA_951216915.1
Location
OX578241.1:1796984-1830865[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 30 0.016 1.2 10.4 0.1 1 23 514 537 514 537 0.95
2 30 0.062 4.8 8.5 3.8 2 23 744 765 743 765 0.95
3 30 0.00011 0.0082 17.2 0.3 2 23 808 831 807 831 0.97
4 30 0.12 9.4 7.6 0.2 1 23 837 859 837 859 0.93
5 30 0.011 0.84 10.9 5.3 1 23 865 887 865 888 0.96
6 30 1.6 1.2e+02 4.1 0.0 2 13 898 909 897 912 0.88
7 30 1.6 1.2e+02 4.1 0.0 2 13 929 940 928 943 0.88
8 30 1.6 1.2e+02 4.1 0.0 2 13 960 971 959 974 0.88
9 30 1.6 1.2e+02 4.1 0.0 2 13 991 1002 990 1005 0.88
10 30 1.6 1.2e+02 4.1 0.0 2 13 1022 1033 1021 1036 0.88
11 30 1.6 1.2e+02 4.1 0.0 2 13 1053 1064 1052 1067 0.88
12 30 1.6 1.2e+02 4.1 0.0 2 13 1084 1095 1083 1098 0.88
13 30 1.6 1.2e+02 4.1 0.0 2 13 1115 1126 1114 1129 0.88
14 30 1.6 1.2e+02 4.1 0.0 2 13 1146 1157 1145 1160 0.88
15 30 1.6 1.2e+02 4.1 0.0 2 13 1177 1188 1176 1191 0.88
16 30 1.6 1.2e+02 4.1 0.0 2 13 1208 1219 1207 1222 0.88
17 30 1.6 1.2e+02 4.1 0.0 2 13 1239 1250 1238 1253 0.88
18 30 1.6 1.2e+02 4.1 0.0 2 13 1270 1281 1269 1284 0.88
19 30 1.6 1.2e+02 4.1 0.0 2 13 1301 1312 1300 1315 0.88
20 30 1.6 1.2e+02 4.1 0.0 2 13 1332 1343 1331 1346 0.88
21 30 0.36 28 6.1 0.0 2 19 1363 1380 1362 1383 0.86
22 30 1.3 1e+02 4.4 0.2 1 23 1462 1484 1462 1484 0.96
23 30 3.6 2.8e+02 3.0 7.2 1 23 1491 1513 1491 1513 0.95
24 30 0.0024 0.19 13.0 1.8 1 23 1564 1587 1564 1587 0.95
25 30 0.0016 0.12 13.5 0.8 1 23 1594 1617 1594 1617 0.98
26 30 0.0067 0.52 11.6 0.2 2 23 1639 1661 1638 1661 0.96
27 30 0.0042 0.32 12.2 4.4 2 23 1683 1705 1682 1705 0.95
28 30 0.0022 0.17 13.1 0.5 3 23 1747 1767 1745 1767 0.96
29 30 0.00011 0.0086 17.2 0.1 1 23 1773 1795 1773 1795 0.98
30 30 0.00067 0.052 14.7 0.7 3 23 1803 1824 1801 1824 0.95

Sequence Information

Coding Sequence
ATGGAGGAGCCTCAACCTCCTCTAATATTGTGCATGGAGAATATGTCCGGGGAAGAGGTGGCACTGCCGATTGAGCCTCATGATGATTTTCAAACGTTCCTAGATAAGGCTAAATCACTACTAGGTTTCGACGTTGATATAAATTCGATCACAAGAAACCAACAAGTTTCTCTAAATGATAACATTTACCAATTCCTCATAACCGCTGAGAATACGGCTGATGGTGGCTTGGACACACAAAACTTTGATCAAATGTTGGAGCCAAACGATGGGTCTAATGACCTAGTGTACATTTTAGATGATGGCACTCAAATACGAGCTTCACAAATACACTTTGATAATGAAGATCCACCCGTAGACCTTACAGCAGAGAAAATACCTTTTGTTAAATATACAGATGATTGTGTTGATGATTTAGATTTAGAAAACCTTAATATTGAGGAaactaaaaactataatatcatTGAAAGTCCTGTATCACGATGGTCTAGTAAAAATTCTAGTCCAAAATGCAGTTTCGTCAACAGTCTACCATTCAAACTGGTTTGCAACAATACTTCGGCTTTCGAAGCTCAATTCACGAAATTTCTAGAAGCAAACACAGCTAAAACTTACGCGACTTTGAACCCTGTCGCTAATAGAAATAAGTCTCCTCGGAGTTTGATTAAGGAGAACTTTAAAAAGTTTGAAGATAATTACCAGAGAGACGATTTGAGTTATACTCGGGAAGATATTTTGAATATGTTCAAAGATTCTCCTGTAGCTTCTTTACCATATGAAAACCACGAGAGAAGACATGTAAGGAAAACTGATCCTTCTAGGCTAGTACATAAGAACTGGAATGCGAAGCCAACTTACGTGGATATAGGCGGGGTTCTGATTGGAGGAAGCGAGAGccaaatatgttttatttgcgGTAAACACGTAGATAAGAATGCAGATAAGCTATATCTATTTGATAACGAAGACCAAAAGATACACAGATGTTCTCCGCAAAAGAAAATGTCTACACAACTGAAGATTATATGTGAAAAATGTCTTAATGAAAACTTCATGCCTTGTAGAATGAAAAGTGCTAACCAATTTCTGAACCCAGACGAGTATTTAGTAATACGTAATAATCAGCAGTACATTTTCCAAAAGACGAAAAATTTCAAGTATTGCGGTGCCAAAATCATAGACAAAGAAGTAACAGATAAAGATGAGTTGGTCAAAGTTGAAATTGGATCTGATGGTGAAATAGTAACGAAACCAATAGACAATGACTCTAGGTCTGAGGACGTTATAATAGTAAAGGATGAAATGAGGGACAGCTCCAGTGACGTTGAGGTTATTGAGCCGGAATCGGAGATTGATAAAATTGTCGATAACTTGGAGGATGCCGATGAGGACGTTAAGCAATTCTTGGGGAAGTATTCGTGTGATGTTGAAGATTTGAAGGAATTGAAATGCAGATTCTGCGAACAAATATTTGCGGCTCTACCGGAAGTGATAGAACACGGTGAAACACATAAGCACAGCTTGGAAGATGGTGAAGTGTACCCTTGCCCTCTATGTAATTATGGTTATGCCAACTTTAAATGGCTGAAGGGTCACCTGAAGGCGGCACATGATAAACCTGAAAAGAAAAATGAAGAAAACAAGGAAGAATCTAAAGATGACATCAAAATTGATACAGATAAAACCACTCCAGTGGAATCACCTATAGCAAAACGTACGCGAAGCTCCATCAAAAAGTCGGAGAGCGATAAAAATGATAGTCCCGAGCACAAAGAAGATGAGAAACAGTTAGATTCCAATGCTGAATCGACTGAGCGTATAATAAAAACGGAGGTGAAACAAGAATGCCTCGAGTCCAGCGATGATGAGATATGGATCGTGCAGACCGCAGATGATGAAGCGTCCAGGCAACTGCAGATATTACTTGGTGCTGCCAAGggtAAAGTTAAAGAAACTGATGACTCAAAGGAAACCCATAAATGTTTGAATTGCAGTCAAATAATAGAGTCAACAGAAATCACGTCCGCACACAAATGTCTAAGAAGACGGGGAAGAAAACGGAAGACTACTGGGAAAGATGACAATCTACTGTGCATACCTACCCGGGAAGATTTCtataagAGAGCTCAAGGCAGACCGCGAGCTgtaaatctatctaataacgaTTTACTTGTACCGaggCCTCGTAAGAAAAGGAATAAAGAAGCCAGTTCAGATCCACAAATTGTGACGTGTCATAATTGTAATGAATCTTTTACATCCAAAGTTCGACTCAAGTTCCATATGCAATTCCACGAGTCATCAAATATGCTATCATCTGACGGACAGTACTCTTGCTACGATTGTGAAAACGCTACTTTCGGCACTGAAACTGAATTGTTCGACCACGTACACTTCCAACATGGGAAGCAGAAGAGGTGGCAGTGTCCGGTTGATGGGTGTGGGAAGACTTTCTATCTCAGAGCAACACTAACGAAACACAGTCGCACGCACACAGACACCCGTCGGTATGTGTGCGTGACATGTGGTAAACGGTTCCTCGACAAGCAGACACTTGACGAACACGGTGTCACACATCTGCAGATAAAGCCGTTCCAATGCCACATCTGCCTGAAGCAGCTGACGCGGCGGTCCCGGCTCCGCATGCACCTGCGCGCGCACCACGAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGTGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGTACAACTAGATATAGTGAAGGAGCTGGCGCCGCGGCTGGTGCTCGTGTGCGCAGTCTGTGGACGCGCCTTCAGGGACCACGGGGGGGCGCAGGATCACGCTACAAAATCGACGGAATGCATAGAAGCTTTCGCCAGCGAGCTGAAGGAAGAAGCTGAAGAGGTGACGGTTCAGCTGTCGCCCACTAGTGGACTTGTCAGGCATACGGTGCAGATTGTTGAATCTCCAAAGTTATCGAAGCCCATACATCGCGAGGTGTCGAGCGGGCTGGGCTCGGCGCTGGCGGCGCAGATACCGGACGAGTGCCGGACCATCATACGAGTTGTGGAGATTGAGAAGGCGTTCCGCTGCGAGTTCTGCGAGGACGTGTTCTACTTAGAAGACGGGTTGAACAGCCATCGTGTAATACATAAGGGTGTCAAAAATCCATTTACATGTCACATATGTAAAGTGAGCTTCGCTACTTACTCCAGATGCACAACCCATAAGACGACTCACGGCTTCTACAAGCGACCCCTGGCGGAAGCCAAGCGGTCGGCGGCCCTCGGGGCGGCGGGGCCCCCGGGGACGGCGCCGGGGGGCCCGGGGGCCTCGGGGGACACGCACACACCTATACTGGGATATGGAGACTTTCCTGTCGTGAAACATTTCTTGTGCGAGgaTTGCGGCCGGTCGTACCTCCATTGGACATATTTGCAAGTCCACCGACGAATGAAGCACGCAAATGAAAACTTTGTATACAAATGCAATCAATGTGATCTCACCTTTCCTAACAgCTGGAGTGTAGCATACCATCGGAAGAAATTACACGGAAAAACTGGGCAAAATTTCCCCAATCATACCACTAAAATGGTCAGAGAAGATTATAGGATACCCTGCAGGGATTGCGACGAGGTCTTGCCGAACAAAACTGCACTCTATAAACATAGGAAGAAGGAACACAGCGATATATCGCTGCGTTTTAATAGTAAACCAAATGAGACCGCCCCCCACACTACTACAGTCAGCTGCGGCCATTGCGGACTGAGCTTCCCACATGCGCACGATTTGCATACGCATCTCAAACAAGTGCACGAGCACACGGCGACGCACCCGTGCGCGGTGTGCGCGGCGCACGCGCGGGCGGGGGCGGTAGGGGCGGtaggggcggtgggggcggcgggggcggctaCAGGGGCGGCGCGGCGCACGCACCTGTGCCCGGTGTGCGCGCGCGTGTTCCGCACGGCGTCGATGCGCGCCGACCACCTGCGCACGCACACCGACGAGCGGCCCTACCCCTGCGACGTGTGCGGCCTCGCCTTCAGACGGTCGACGGCGATGCGCAACCACCGGCTGATCCACACGGGCGTGCGCGCGTGGGCGTGCGGCCGCTGCCCCAAGCGGTTCCGCATCCGCTCCGACCTGCGCACGCACCTGCGGCTCAAGCACCCCGCGCACCTCGCGCTCCTTGAGgtgGAAGGCTTAAATCCGACCACGGAAGAGGTGATGAAATACCTGAACGTGAACAACATACCCCAGGACAAGGTTATAGAAATATCCAAAATATCATTCTCAAAGGGCACCTCGAGCATTATACCAAACAGTGCTCGTGCATTGTCGATGTTGAGCAATATAACCCGTACACAAATTACTTTTAACCAGCCCCCACCGCTTCATAATgATGAATTCCAGCCTGTTCGTCGCGGTAGGGGCATAGCGAAGAACCCGCGCAGACCCAAGATACTTCAACGCGGGGGTGATGAGGTACCCCACCCAGATCCGAACAATTATCCTATAGCTGTCAGCGTTACGGGCGAgGAATTATCAGAACTAAACGTACAGCTATTGCTAAGAGATGGGGTACTGGTCAATGGGAACCAGATGGTACAACTGCAATTAGACGACTCTATGTTAATGTAG
Protein Sequence
MEEPQPPLILCMENMSGEEVALPIEPHDDFQTFLDKAKSLLGFDVDINSITRNQQVSLNDNIYQFLITAENTADGGLDTQNFDQMLEPNDGSNDLVYILDDGTQIRASQIHFDNEDPPVDLTAEKIPFVKYTDDCVDDLDLENLNIEETKNYNIIESPVSRWSSKNSSPKCSFVNSLPFKLVCNNTSAFEAQFTKFLEANTAKTYATLNPVANRNKSPRSLIKENFKKFEDNYQRDDLSYTREDILNMFKDSPVASLPYENHERRHVRKTDPSRLVHKNWNAKPTYVDIGGVLIGGSESQICFICGKHVDKNADKLYLFDNEDQKIHRCSPQKKMSTQLKIICEKCLNENFMPCRMKSANQFLNPDEYLVIRNNQQYIFQKTKNFKYCGAKIIDKEVTDKDELVKVEIGSDGEIVTKPIDNDSRSEDVIIVKDEMRDSSSDVEVIEPESEIDKIVDNLEDADEDVKQFLGKYSCDVEDLKELKCRFCEQIFAALPEVIEHGETHKHSLEDGEVYPCPLCNYGYANFKWLKGHLKAAHDKPEKKNEENKEESKDDIKIDTDKTTPVESPIAKRTRSSIKKSESDKNDSPEHKEDEKQLDSNAESTERIIKTEVKQECLESSDDEIWIVQTADDEASRQLQILLGAAKGKVKETDDSKETHKCLNCSQIIESTEITSAHKCLRRRGRKRKTTGKDDNLLCIPTREDFYKRAQGRPRAVNLSNNDLLVPRPRKKRNKEASSDPQIVTCHNCNESFTSKVRLKFHMQFHESSNMLSSDGQYSCYDCENATFGTETELFDHVHFQHGKQKRWQCPVDGCGKTFYLRATLTKHSRTHTDTRRYVCVTCGKRFLDKQTLDEHGVTHLQIKPFQCHICLKQLTRRSRLRMHLRAHHEELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQVQLDIVKELAPRLVLVCAVCGRAFRDHGGAQDHATKSTECIEAFASELKEEAEEVTVQLSPTSGLVRHTVQIVESPKLSKPIHREVSSGLGSALAAQIPDECRTIIRVVEIEKAFRCEFCEDVFYLEDGLNSHRVIHKGVKNPFTCHICKVSFATYSRCTTHKTTHGFYKRPLAEAKRSAALGAAGPPGTAPGGPGASGDTHTPILGYGDFPVVKHFLCEDCGRSYLHWTYLQVHRRMKHANENFVYKCNQCDLTFPNSWSVAYHRKKLHGKTGQNFPNHTTKMVREDYRIPCRDCDEVLPNKTALYKHRKKEHSDISLRFNSKPNETAPHTTTVSCGHCGLSFPHAHDLHTHLKQVHEHTATHPCAVCAAHARAGAVGAVGAVGAAGAATGAARRTHLCPVCARVFRTASMRADHLRTHTDERPYPCDVCGLAFRRSTAMRNHRLIHTGVRAWACGRCPKRFRIRSDLRTHLRLKHPAHLALLEVEGLNPTTEEVMKYLNVNNIPQDKVIEISKISFSKGTSSIIPNSARALSMLSNITRTQITFNQPPPLHNDEFQPVRRGRGIAKNPRRPKILQRGGDEVPHPDPNNYPIAVSVTGEELSELNVQLLLRDGVLVNGNQMVQLQLDDSMLM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-