Basic Information

Insect: Tethea ocularis
Gene Symbol: ZFX
Assembly: GCA_963555595.1
Location: OY741973.1:511489-518992[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 2.7 1.7e+02 3.4 0.7 6 23 305 323 305 323 0.96

2 23 6.2 4e+02 2.3 0.0 3 23 335 356 334 356 0.89

3 23 2.4e-07 1.6e-05 25.6 1.1 2 23 379 400 379 400 0.97

4 23 3.6e-05 0.0023 18.8 1.0 1 23 407 430 407 430 0.96

5 23 0.18 11 7.1 0.2 1 23 436 458 436 458 0.93

6 23 0.00026 0.017 16.0 4.3 1 23 464 486 464 486 0.98

7 23 0.081 5.2 8.2 3.5 1 23 628 650 628 650 0.96

8 23 0.00042 0.027 15.4 2.0 2 23 657 679 656 679 0.92

9 23 2.4e-06 0.00015 22.5 1.5 1 23 685 707 685 707 0.97

10 23 4.3e-06 0.00028 21.7 4.4 1 23 713 735 713 735 0.98

11 23 0.0005 0.032 15.2 0.4 1 23 741 763 741 763 0.98

12 23 5.7e-05 0.0037 18.1 0.4 1 23 769 791 769 791 0.94

13 23 0.018 1.2 10.3 4.1 1 23 797 820 797 821 0.94

14 23 5.6e-07 3.6e-05 24.4 1.9 1 23 931 954 931 954 0.97

15 23 7.9e-06 0.00051 20.8 4.5 1 23 960 982 960 982 0.99

16 23 0.00053 0.034 15.1 1.5 1 23 988 1010 988 1010 0.97

17 23 0.00021 0.013 16.3 1.0 1 23 1015 1037 1015 1037 0.97

18 23 0.017 1.1 10.3 0.1 3 23 1200 1221 1199 1221 0.95

19 23 0.00094 0.061 14.3 0.1 1 19 1227 1245 1227 1249 0.94

20 23 5.9e-05 0.0038 18.1 0.6 1 23 1255 1277 1255 1277 0.99

21 23 0.016 1 10.5 0.2 3 23 1285 1305 1283 1305 0.95

22 23 0.011 0.72 10.9 1.8 1 23 1316 1338 1316 1338 0.96

23 23 0.00053 0.034 15.1 4.5 1 23 1347 1370 1347 1370 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	2.7	1.7e+02	3.4	0.7	6	23	305	323	305	323	0.96
2	23	6.2	4e+02	2.3	0.0	3	23	335	356	334	356	0.89
3	23	2.4e-07	1.6e-05	25.6	1.1	2	23	379	400	379	400	0.97
4	23	3.6e-05	0.0023	18.8	1.0	1	23	407	430	407	430	0.96
5	23	0.18	11	7.1	0.2	1	23	436	458	436	458	0.93
6	23	0.00026	0.017	16.0	4.3	1	23	464	486	464	486	0.98
7	23	0.081	5.2	8.2	3.5	1	23	628	650	628	650	0.96
8	23	0.00042	0.027	15.4	2.0	2	23	657	679	656	679	0.92
9	23	2.4e-06	0.00015	22.5	1.5	1	23	685	707	685	707	0.97
10	23	4.3e-06	0.00028	21.7	4.4	1	23	713	735	713	735	0.98
11	23	0.0005	0.032	15.2	0.4	1	23	741	763	741	763	0.98
12	23	5.7e-05	0.0037	18.1	0.4	1	23	769	791	769	791	0.94
13	23	0.018	1.2	10.3	4.1	1	23	797	820	797	821	0.94
14	23	5.6e-07	3.6e-05	24.4	1.9	1	23	931	954	931	954	0.97
15	23	7.9e-06	0.00051	20.8	4.5	1	23	960	982	960	982	0.99
16	23	0.00053	0.034	15.1	1.5	1	23	988	1010	988	1010	0.97
17	23	0.00021	0.013	16.3	1.0	1	23	1015	1037	1015	1037	0.97
18	23	0.017	1.1	10.3	0.1	3	23	1200	1221	1199	1221	0.95
19	23	0.00094	0.061	14.3	0.1	1	19	1227	1245	1227	1249	0.94
20	23	5.9e-05	0.0038	18.1	0.6	1	23	1255	1277	1255	1277	0.99
21	23	0.016	1	10.5	0.2	3	23	1285	1305	1283	1305	0.95
22	23	0.011	0.72	10.9	1.8	1	23	1316	1338	1316	1338	0.96
23	23	0.00053	0.034	15.1	4.5	1	23	1347	1370	1347	1370	0.97

Sequence Information

Coding Sequence: ATGAACGAAGCTCCTCTACAAATATACCTCCCTAAGTCAGAATCGTCAACATCGCAGAGACATTTAGAATTACCACCAGCAACACAAGTTAATCTTGAAGACGTTGAAGACTTCTCCAATGTGTGTCGGATATGTGCAACGGTCACAGAGCTGGTCATCCCCATATTTAACGGAGAGGGACTGCTCAACAACCTAGCTGAGAAGATATGCAAGCATTTGCCTATACAGGTGAGCGAGGAGGACGTGCTGCCGCGCGTGGTGTGCTACCAGTGCTCCAGCACCATCCTGGCGTGGCACGAGCTCGTGCAGTGCTCGCTGCAGGCCGACCAAGCACTCAACACCAGGCTGCTCACTTCTCGAGCTGCACACGATGGACCAGATAATCAGGCAGCTCAAGAATGGCATAAATTCAAAATAGTACATTTACCATTATGTTTTCTGCAGGAACCACATCCAAATAATGTCAAACCTCAAATCAAAACAACAGACCGAGATAACAAGTCGGAATCTCCGttaatattttaccaaaatgtaagaaatgtgCTGGTCGATTACTGTCGTACACTGAAAATCGGCGGAGATAACTTAGATATGAAATTTGTTTGTACCAAATGTGCAGAAAAACCTGCTCTATCATCTGTGGAACATTTAGCCGCACATCTGTCGTGCCATAAGCTGGACGCTCAGAGTACGGAGGCTATTCAAATATTCATACAGGAATACATCATTTTTGAAGAAATCCTAGATGATGAAAATTTTTACAGAGACGATTCATCCGAACCGGAAGAAAAGTTAGAAACGCTCCCATCTTTCTGTTGTCCATTCTGTGAAAACGTATTTTCGTCGACAACTCGGCTCATTTGTCATCTCAACAAGCATGTCGAAGTCAGCATTGACGACGGCGTGATCTGCTGCGATATATCATACGACGACAGAAAGAGTTTCGTCCACCACCTGCAGCAGAAACACGTGGATCGTTCCATAGACAGCGGGACGAACGTATGCCGCAGCTGTGGCTTCGTCGCCGAAGATGCCACCGGCCTCGAGGCGCACCTGACGGATGCCCACAGCCAAATAGAGGAAACTAAAGTGAGGAAGGAGCAGAGCCTAAAAAATCAGAAATACATTCCGGCCGTATGCCCCGAGTGCAACAAAACATTTTCCAATAAATACAACATGTTCGTTCACATGAGGAGCCACAGCGGTCAGGTGAACGCGTACCCGTGCGATAAATGTAACAAAAGCTACAAAGCGCAGGGTAATTTGAGAAAACACAAGAAACTGGCGCACGAGGGGATTCTGAGCTACCTCTGCACGAGTTGTGGCGAAGCTTTCCCCACGCGGACTACGCGAGACGTCCACGCTCGGCTACACTCCGGAGACAAACCTTACAAATGCGACCACTGCGGAAAATGTTACAGAGCCAAAAATACTCTCGACCGACACCTAGAAATCCATTTAAACATAAGGAAGTGGAAGCCCTGCGTTAAAAACGAAACTGAATCGTCGAGCGACAGCGACACCGATCGCAGATACTCGCCTATCAAACGCGGAGTCGACCTATCGGACGAGAACTCCCTCGACGACGACAAACCGCTGTCGGTCGTAGCCAAAAAGAAAtcctacaatatttacaacacatTTTATAGGGCGCTAATCAATTTCAGAGACCACTACGTTTCCGACCACGACAAATGTAGCTACCCCGAATTCACGGATTCGAGCCACTCCGAGAGGAGCTTCGACGAACGTAACGACGAAAGCGATAACATCGAGAGTTTCGACGACTTGACGCAATGGAACATGAGGAGGGACAGAATGGACGACGAGACGCGCCTCGAGCTGACTCAGGCGCAAACCAAAATTAACGGAAAAGTTTTCTACACGTGCAAAGAATGCGGAAAGAACTTGAGCTCCTCGCACACGTACGTGTTCCACAAGCGCATTCACACCGGCGAGCGGCCCTGCGTCTGTCACATATGCGGGAAGCAGTTCCGAGCCCCGAACGGCCTGCAGCGCCATCTGACGGAGACGCACGAGCGCGCCCGGCGGCACTCGTGCCCGATCTGCCTGAAGAACTTCGCCAACTCACAAAATTTAAAACAGCACATGCGCATCCATACCGGGGAGAGGCCGTTCATCTGCTCCCACTGCGGCAAGCGGTTCACCCAGAGCGGGTCGCTGCACGTCCACCTGAAGACTCACAGCGAGCAGGTCCCGCACCAGTGCGCCGAGTGCGGCGCCAAGTTCCGGGTGCGGGCGGGCCTGGCGAGGCACCGGCTCAAGCACAGCGGCGAGCGGCCGCACGTGTGCCCGCAGTGCGGCCGCGGGTTCCGGCAGCGGCACGAGCTCGCCGCCCACGCCCTCGCGCACACCGACTCCAAGCCGCACGCCTGCGCACTCTGCCCGGCCACCTTCAGGCAGCGCCGGGCTCTCCGCCACCACGCCAAGAGGATGCACCACGAGGAGACCGAGGTAGagcgcaaaaatattttttttgttgtttttttttatcgattccACCCCGCTAACGTATCTCCCCCCGATTGCGTTTCCAGAGATGAGATTCCGACGCTCACGGTGGAGGTCAAAATCGAACCGACCGATAGCGACGAGCGGGAGGGGGCGAGCGGGGGCCCACGACAGCGGCGGCTGCGGTCGGGCAGCGGGCCGTCGACGGTGGTGGTCGGGGAGGACGGGCGGCGGTACGGGCTGTGCGGGGTCTGCCACAAGCACGTCCACGTGGGCGTGTGGAGCCGCCACGTGGGCAGCCACTCCCGCGCGCGCGACCACCGCTGCGACAAGTGCGGCGCCGGCTTCAGCGACCGGAGCAACCTCACGCGCCACCAGCGCTCGCTGCACGCCCAGCGCCGGCCCTACGTCTGCGACACCTGCCACAAGGCCTACACGAGGAAGTACCACCTCGAGGAGCACGTGAGGACGCACTCGGACGCCAGGGACTTCGTGTGCGACGCGTGCGGGAAGACGTTCAAGTCCGGCACGTGCCTGCGGGTGCACCGGCGCGCGCACGACCGGCTGCGCTTCCACTGCCTCGAGTGCGGCGGCCGCTTCCGCAGGCTCGGGGAGCTCAAGTCGCACATGAGCGTCCACACCGGCGAGAAGGCCCACGCGTGCCCGTTTAACGAACCGCCCGATTTGATCGCTCCGACGGAGTTCGCGAGGCGCGCCCCCTCCCCCCGCCCCGTCGCAGTACAGGGCTGCACCCCCGACGACCCGATGCTTCCCTGCGGCGAGGGCGACACCCACGTCGACGGGAGGGACGCGTCGCCGGAGTCGCGACCGAGGCGGCACGGAACGAGCGAGCCCGCCGGCGACGACGGTCGAGTGCTCCACGAAAGCCTCGACGTCAAATCCGAGGGGGAGGGCCCCGACGACGAGAGCGACGACCTAGAGGACGAGTTCGCCGATCACAGCGACGCGGAGTTCGGGGCGCTCCCCGAGTCGGTCTTCGAGGCGATCGAGGACACCCGGGACGGCCTCCCGACCGCGGACGACCCCGCGAGCCCGCCGCCGGAGCCCGACCCCGCCCCCGCCGCGCCCCCCGGGGAGCCTACGAGTCGGAGGAGACCTCGCGCGTGCCCCGTCTGCTCGAAGGTGTACACGGCCCCGTCGAGCTACTTCTACCACGTGAAGTACTCGCACCGCGAGACGAAGGAGCACGAGTGCGAGGTGTGCGGGCGCAGGTTCGGCACCGCGGCCAGCCTGCGGCAGCACGCGCCGATCCACACCGGCGAGCGGCGCTACGAGTGCCCCGAGTGCTCGAGGCGGTTCGGGTCGCGGGCCAGCCTCTACAACCACCGGCTGACGCACGACTCGGACAGGAAGTGGGCGTGCGCGCAGTGCGGCCGCGGGTTCGGGTCGCGGTGCGGGCTGGTGCGGCACGTGGCGCGCCACGCGGGCGCGGAGGGGGCGGGGGAGCGGCGGCACGCGTGCGGCACGTGCGCGCGCACCTTCGCCGTGCGCTGCGACCTGGTGCGGCACGCGCGCACGCACTCGCGCCCGCACCCCGACGACCGGTACGCGTGCCACCAGTGCCACCTCAAGTTCGCGCAGCCCAGGTACTTGAAGGTACATATCAAGAAGAAACATTCCTGA
Protein Sequence: MNEAPLQIYLPKSESSTSQRHLELPPATQVNLEDVEDFSNVCRICATVTELVIPIFNGEGLLNNLAEKICKHLPIQVSEEDVLPRVVCYQCSSTILAWHELVQCSLQADQALNTRLLTSRAAHDGPDNQAAQEWHKFKIVHLPLCFLQEPHPNNVKPQIKTTDRDNKSESPLIFYQNVRNVLVDYCRTLKIGGDNLDMKFVCTKCAEKPALSSVEHLAAHLSCHKLDAQSTEAIQIFIQEYIIFEEILDDENFYRDDSSEPEEKLETLPSFCCPFCENVFSSTTRLICHLNKHVEVSIDDGVICCDISYDDRKSFVHHLQQKHVDRSIDSGTNVCRSCGFVAEDATGLEAHLTDAHSQIEETKVRKEQSLKNQKYIPAVCPECNKTFSNKYNMFVHMRSHSGQVNAYPCDKCNKSYKAQGNLRKHKKLAHEGILSYLCTSCGEAFPTRTTRDVHARLHSGDKPYKCDHCGKCYRAKNTLDRHLEIHLNIRKWKPCVKNETESSSDSDTDRRYSPIKRGVDLSDENSLDDDKPLSVVAKKKSYNIYNTFYRALINFRDHYVSDHDKCSYPEFTDSSHSERSFDERNDESDNIESFDDLTQWNMRRDRMDDETRLELTQAQTKINGKVFYTCKECGKNLSSSHTYVFHKRIHTGERPCVCHICGKQFRAPNGLQRHLTETHERARRHSCPICLKNFANSQNLKQHMRIHTGERPFICSHCGKRFTQSGSLHVHLKTHSEQVPHQCAECGAKFRVRAGLARHRLKHSGERPHVCPQCGRGFRQRHELAAHALAHTDSKPHACALCPATFRQRRALRHHAKRMHHEETEVERKNIFFVVFFYRFHPANVSPPDCVSRDEIPTLTVEVKIEPTDSDEREGASGGPRQRRLRSGSGPSTVVVGEDGRRYGLCGVCHKHVHVGVWSRHVGSHSRARDHRCDKCGAGFSDRSNLTRHQRSLHAQRRPYVCDTCHKAYTRKYHLEEHVRTHSDARDFVCDACGKTFKSGTCLRVHRRAHDRLRFHCLECGGRFRRLGELKSHMSVHTGEKAHACPFNEPPDLIAPTEFARRAPSPRPVAVQGCTPDDPMLPCGEGDTHVDGRDASPESRPRRHGTSEPAGDDGRVLHESLDVKSEGEGPDDESDDLEDEFADHSDAEFGALPESVFEAIEDTRDGLPTADDPASPPPEPDPAPAAPPGEPTSRRRPRACPVCSKVYTAPSSYFYHVKYSHRETKEHECEVCGRRFGTAASLRQHAPIHTGERRYECPECSRRFGSRASLYNHRLTHDSDRKWACAQCGRGFGSRCGLVRHVARHAGAEGAGERRHACGTCARTFAVRCDLVRHARTHSRPHPDDRYACHQCHLKFAQPRYLKVHIKKKHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -