Basic Information

Insect: Tenthredo mesomela
Gene Symbol: ham
Assembly: GCA_943736035.1
Location: CALSEY010000035.1:846182-872298[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.023 4.7 9.2 0.3 2 23 299 321 298 321 0.93

2 9 0.99 2.1e+02 4.0 0.4 1 23 328 351 328 351 0.82

3 9 9.2e-09 1.9e-06 29.3 1.4 1 23 357 379 357 380 0.96

4 9 8.3e-07 0.00017 23.2 1.7 1 23 386 408 386 408 0.95

5 9 1.4e-05 0.003 19.3 4.9 1 23 414 436 414 436 0.99

6 9 0.00018 0.037 15.8 1.9 2 21 444 463 443 464 0.95

7 9 7e-09 1.5e-06 29.7 1.2 1 23 788 810 788 810 0.99

8 9 3.7e-07 7.6e-05 24.3 1.7 1 23 816 839 816 839 0.97

9 9 1e-05 0.0021 19.7 3.4 1 23 845 867 845 867 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.023	4.7	9.2	0.3	2	23	299	321	298	321	0.93
2	9	0.99	2.1e+02	4.0	0.4	1	23	328	351	328	351	0.82
3	9	9.2e-09	1.9e-06	29.3	1.4	1	23	357	379	357	380	0.96
4	9	8.3e-07	0.00017	23.2	1.7	1	23	386	408	386	408	0.95
5	9	1.4e-05	0.003	19.3	4.9	1	23	414	436	414	436	0.99
6	9	0.00018	0.037	15.8	1.9	2	21	444	463	443	464	0.95
7	9	7e-09	1.5e-06	29.7	1.2	1	23	788	810	788	810	0.99
8	9	3.7e-07	7.6e-05	24.3	1.7	1	23	816	839	816	839	0.97
9	9	1e-05	0.0021	19.7	3.4	1	23	845	867	845	867	0.99

Sequence Information

Coding Sequence: ATGGTTGACTACAAAGTGAGCGGTGGAAGTAGCGACGAGGGCGAGACAGCCGGTGGTACTGGCGGGGGCGGAGGTCCTGGAGGTGAGGATACGGACCTTGAGGAAAATTCGGTACGGCCAAACAGCAACCCCATATATCGTGACCTGAAACCACTTCACGCAACGAGTGCCCACGACGTTCCACAGGAGTATCCGCAAACCACGACAGCTTACCAGCAGGAATTCAACCCCGCTGCAATGGAAAGACCAACCTATGAGAAACAGGCACAACAACCCTTGGTCAGGGAGGATGAACTCAAGCCTTGGGGCTACGAAAAAACAGACCGTAAAGACTACGCGAGAACTCCTGAAGTCTACCGTGGAGAGTTTCGTGATATTATGAAGCAGGAACCTCGCGCGATGAAAGAAACGCCATTGAGAGAGTGGATATCCCCGGTTCCGGAAGTGGAGGTTGGTCGATCACCGCTAAGCGGACCACAGGTTAGAGCGCGAAGAGACATCGCGAGGGGTGCTAGATTTGGACCGTTTTTTGGCAAATGGACCAGCGAACCATTGAACCCACATTACGCATGGGAGATTAGAATTTCTGGAAGCGGCGTCCGAGGGTGGCTTGATGCATCTCACGAAGCTAGCAATTGGCTCAAGTATGTCCGAAGTACGGAGAGTCCTCACGCGGTCAACATGCGTCACGTTCTCATCGGTGGACAGGTCGTTTACGAAACTATCCGAGATATAGCCGCAGGTGAAGAGCTTCTCTTAGGTCACCGAGAACCATTACAGCTGCAGGATATGCTTGGTGAGAACACTGCTGAGGATAGAAGTGACAGAGAGACCGCTTCCCAGCACAGTGGAACTGTCGACGAAGACAGAGAAGAGGACGAAGACGGTGATATTAGATGCACAGTATGCGACAAGCCTTTCCAGGATATTGACTTACTCGACGGACATCTGGTGACTTGTCATAGGTATCCAGCTGAACAGTATCGGTGTGAGACTTGTCACAGAGGATATGCATGGAGGCCACTGGTTGTACGTCACCGTTCGATCGTTCATGGAGACCTGAAGAAGTACCAGTGTGAAAACTGCACAAAGGTGTTCACTGATCCCTCAAATCTCCAGCGCCACATTAGGGCACATCACGTTGGCGCCAGAAGTCACGCCTGCCCAGACTGTGGGAAGACGTTCGCCACCAGTTCCGGCCTAAAACAGCATACCCACATCCACAGCAGCGTCAAGCCCTTTCAATGCGAGGTCTGCTTCAAGGCTTACACCCAGTTCTCCAATCTTTGTCGACATAGGCGAATGCATGCCGATTGTCGTGCACAGATAAAGTGCGGTAAATGCGGACAGTCTTGCAGCTCAGCATCGTCACTAACGAAGCATAAACGATTTTGTGACTCAACCGGGCCACCCGGACCAACTGGAGCTATGCCACAGCTTCCAGCCTCGGGACCAAGTCCGTTCTTGGTGTACCCAAGACCTCCTGGATCGTTACAGGGATCCTTGCCATTCTACCCACCAAGTCTGATGGGTCCTTACCCTGGGATTTTTCCCAACACACCGAACTTTTTAAACAGCTCGCTCCTGTTCCCACAAAAAATGGAGGAGCTTGAAAAGCGGTGTGATAGCCCGAAGAAGGAGAGATTCACACCGCCCCGTGTTCCTACACACCACAACAAGGTCTCTCCATCCACAGCCGAGGAAGCAACTTCAACCTTTAGACCATCTCCAGCTAGACCCCCGGCTCAACTCACTCCTGAGAGTGACGAGGAGGTGAAATCGAAGCAACCGAAGCCGGAAAAAAACATCAAGGCTGAAGCTATGGAGGAATCGGCTGATCAGCCACTTGACCTTAGGGTCGAAACCAGAAGACGCCAGACCCCCAGCGTTGCTGGTAGCCATAGTCCCTCCCCAATACTTATGGTCGAGGAAACTCAACCTGAACCATGGAAGGTCAAGGATGAAGAACGCATGGAAGCCAGGGTTAAGGAGCTTGCTATCAGCCCAGTCTGCAGTGTGGCGGAACAGCAGCCTCCGACGAACGCACCCCCTCACATGGCGTATCCCCGGCCAATTCATCCGATGTTCCTGGAGGCTATGTACCGCGCTCCATCCGGGACGTTTCCTGGCTTTCCAGGAGGCCCTCCGCCATCTGGGGGACCAGAATCCCGGCTACTACCTCCACCGCCACCTTTCGGACCTACGCGTGGAAGTTTTCCTTTTTTAGCACCGCTAGTGAATGGGCTGAGTGGTGGTCGACCAGGTGGATTTGACATCCTTGCCCGGCCGCCGCTAAGTGCATTCCCCATGTCGCATCATCATCACCATCATCATCACGCTCATGGAAAGATGAAGGATCGCTACTCGTGCAAATTTTGTGGCAAAGTGTTTCCCAGGTCTGCAAACCTGACGAGGCATCTCCGCACTCATACTGGCGAACAGCCCTACAAGTGTAAATATTGCGAGAGGTCATTCAGCATCTCTAGCAATCTTCAACGTCACGTTCGGAATATTCACAACAAGGAAAAACCCTTCAAATGTCCTTTATGCGAACGTTGTTTCGGCCAACAGACCAATCTCGATCGTCATTTGAAGAAACACGAGGCTGATGACGGCAGCGGCGTTGTTGCCGTAGCCGATTCACCAGGAAGTAGCAACGAAAATGAACGGGAAGATTCGTGTTTTGACGAGATCAGGTCGTTTTTCGGCAGAGCTACCGAAGGAGATGGATATGGTGTCCCGCATAATTACCCTGCGTACTTACCCGAGCGATTACACGAACCCCATGACCCTAAAATAGAGGGTGAATATGACGAGGACGAGGACAGTGAAGAGGGAGTATCTCCCCTTGAAGAAGCTGACGGTATGTCGCCCATGGATACGAAAGAATCACCCCCTCCCCAGTACGAGCTCAAGCTTAGGGATAAGCAGGAATTGCTCAACAACAATACGGCCGAACCAGTGATAGAGATATCGACATAG
Protein Sequence: MVDYKVSGGSSDEGETAGGTGGGGGPGGEDTDLEENSVRPNSNPIYRDLKPLHATSAHDVPQEYPQTTTAYQQEFNPAAMERPTYEKQAQQPLVREDELKPWGYEKTDRKDYARTPEVYRGEFRDIMKQEPRAMKETPLREWISPVPEVEVGRSPLSGPQVRARRDIARGARFGPFFGKWTSEPLNPHYAWEIRISGSGVRGWLDASHEASNWLKYVRSTESPHAVNMRHVLIGGQVVYETIRDIAAGEELLLGHREPLQLQDMLGENTAEDRSDRETASQHSGTVDEDREEDEDGDIRCTVCDKPFQDIDLLDGHLVTCHRYPAEQYRCETCHRGYAWRPLVVRHRSIVHGDLKKYQCENCTKVFTDPSNLQRHIRAHHVGARSHACPDCGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHRRMHADCRAQIKCGKCGQSCSSASSLTKHKRFCDSTGPPGPTGAMPQLPASGPSPFLVYPRPPGSLQGSLPFYPPSLMGPYPGIFPNTPNFLNSSLLFPQKMEELEKRCDSPKKERFTPPRVPTHHNKVSPSTAEEATSTFRPSPARPPAQLTPESDEEVKSKQPKPEKNIKAEAMEESADQPLDLRVETRRRQTPSVAGSHSPSPILMVEETQPEPWKVKDEERMEARVKELAISPVCSVAEQQPPTNAPPHMAYPRPIHPMFLEAMYRAPSGTFPGFPGGPPPSGGPESRLLPPPPPFGPTRGSFPFLAPLVNGLSGGRPGGFDILARPPLSAFPMSHHHHHHHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKEKPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVAVADSPGSSNENEREDSCFDEIRSFFGRATEGDGYGVPHNYPAYLPERLHEPHDPKIEGEYDEDEDSEEGVSPLEEADGMSPMDTKESPPPQYELKLRDKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01414411;
90% Identity: iTF_01414411;
80% Identity: -