Basic Information

Gene Symbol
-
Assembly
GCA_963966615.1
Location
OZ016484.1:11019237-11023780[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0012 0.12 13.4 0.1 1 22 147 168 147 170 0.91
2 13 1.5e-06 0.00016 22.5 1.3 1 23 177 199 177 199 0.98
3 13 2.1e-06 0.00022 22.0 6.6 1 23 205 227 205 227 0.98
4 13 0.00015 0.016 16.2 6.1 2 23 244 265 244 265 0.98
5 13 1.9e-08 2e-06 28.4 3.1 1 23 270 292 270 292 0.98
6 13 4.4e-07 4.7e-05 24.2 0.8 1 23 297 319 297 319 0.98
7 13 1.5e-08 1.6e-06 28.7 2.5 1 23 325 347 325 347 0.98
8 13 2e-05 0.0021 19.0 8.1 1 23 403 425 403 425 0.97
9 13 1.2e-05 0.0013 19.6 0.8 1 23 494 516 494 516 0.98
10 13 1.2e-05 0.0012 19.7 3.9 2 23 532 553 532 553 0.98
11 13 7e-06 0.00074 20.4 1.3 1 23 558 580 558 580 0.98
12 13 3.2e-05 0.0033 18.3 3.1 1 23 586 608 586 608 0.93
13 13 0.00021 0.022 15.7 5.8 1 23 614 636 614 636 0.97

Sequence Information

Coding Sequence
ATGAATCGATCCGCAGCAGAGGAAAGCAAGGGAAGGTATGAGAGAGCACACCAAACTACCACCTCGGGTCAAGAGTTGAGGTATCAACCTCACGATAAGGGATGGGATAATATATTGTTCGACAGCGTCGACGGAATAAGACACATCATAGAAGAGCCTCTAGATAACGACGTCTCGACTTTGAGAGGATTCCTTGACTATGTCGAGACTATAACAActcaagaaattaaaatcgagCTACAGGATTCGACGAAAACTAACAACGCCGCTGTTTCCGCTCCTGCAAAGTTTGCTGATAATAATCTAACGAATTTGATGAAAAAGGAATCCCTGGAAAAATCATCGATTCAATACAATGCTTTGCCTGAGCAGCAGGAACTGTTCACCGAGGGTACTGCCGATGTTAATTGGAAGCTAAATGATGGAAATCCAAGCCTTTATCGCTGTGCTATTTGTCAAGTTCAATTCTCCAGTCGAGTTTCTCTGGACAGACACATCGTGGACTTACATCTGGGTACAACGGGTCGTTTCCAGTGCGATATTTGCCATAAAGAATTTTCTCGAGTCTCTGACTTGGCTAGACACAAGCTAATACATTCAGGCGTTAAACCATTCCAATGTAACACTTGCCATAAGCAATTTTCTAGACAAGATCACCTCAAGCAGCACATACTTAGCCATTCGCAATGCTCTGATAGCGAGCTATTCGCTTTTGAAAACGGTTTGAATAGGTGTACTATTTGCCATAAGCAATTATCACGGCCTCAACACTTGAGAACTCACATGCGACAACATTTGGGGACTTTGTTTGAGTGCGATAAATGCAACAAGAGATTTTCACGAGCTTCGCACCTCAGAGCTCACATGCGTCTGCACTTGGGTACATGTTTTCGCTGTGATATTTGccaaaaagaattttctagACCTTCTGATTTAGACAGACATAAGCTTACCCATTTGGACAAGAAATTATTCGAGTGTCCTACTTGCCAGAAGAAATTTTCTAGAAAGGATAATCTGAAAAAGCACATGCTTTCTCATGTGGAATCTATACCACCGAACCAAATTAGCCATCGTCAGAATCACTTTGAGGAAGATTTGTGTttgaattcaaagaaaaattgccAATGCAGTATTTGCGTAGCGAAAATTTCTTTGCCTATCGAATTTGAAGGGCATACGATTATTCACTCTGATATAAGATGCCACGAATGTCACGTTTGCAAGAAATATTTCACTAGGAAAGATCATTTGAAGAGACACCTAGCTTCGCACAAGATCTTACCTCGTGATCAGTCGGTTGATCAATGCATTGCAAGTAGGAAAACCAAGCAGCAAATGCTTTTAAACGTAATTCCAGTTTCAAACTCATTTGATTCTAGAGAAAAATCGGGCGGTCACGATGCCTGCAAAGTAGAGTTTGGTACTAGGTTTAATTACGATGAAAGCATGTGCCCCCATAATtggatagagaaaaaattcgaatgtGCGATTTGTGAGAAGAGATTCAATAGAAAAGTTAGATTAAAAGAACACGTTCGTATGCATGGAGTCGGGAATTTTGAGCTTAACGATGGGGATAAGGATCAAAACAGATGTAATATTTGTCACAAACAATTGTCACGCCCAGAGCATTTAAAGGCACACATGCGACTGCATCTGGGAACACTTTTTAAGTGCGAAACTTGccaaaaagaattttcaagattATCAGACTTGGATAGACACAAGCTGGTCCATTCAGGGCTTAAACAGTTCATATGTATTATTTGCCACAAGCAATTCTCGCGGAAAGATTACCTAAAGAATCACATGCTTTCACATGCTaatcaaaaatcatttgaatgTGACAAGTGCAAAAAGCGCTTCACCTATTTCACCAATTTAAGAAATCACTTGCATCTTCATATAGGGGACTAA
Protein Sequence
MNRSAAEESKGRYERAHQTTTSGQELRYQPHDKGWDNILFDSVDGIRHIIEEPLDNDVSTLRGFLDYVETITTQEIKIELQDSTKTNNAAVSAPAKFADNNLTNLMKKESLEKSSIQYNALPEQQELFTEGTADVNWKLNDGNPSLYRCAICQVQFSSRVSLDRHIVDLHLGTTGRFQCDICHKEFSRVSDLARHKLIHSGVKPFQCNTCHKQFSRQDHLKQHILSHSQCSDSELFAFENGLNRCTICHKQLSRPQHLRTHMRQHLGTLFECDKCNKRFSRASHLRAHMRLHLGTCFRCDICQKEFSRPSDLDRHKLTHLDKKLFECPTCQKKFSRKDNLKKHMLSHVESIPPNQISHRQNHFEEDLCLNSKKNCQCSICVAKISLPIEFEGHTIIHSDIRCHECHVCKKYFTRKDHLKRHLASHKILPRDQSVDQCIASRKTKQQMLLNVIPVSNSFDSREKSGGHDACKVEFGTRFNYDESMCPHNWIEKKFECAICEKRFNRKVRLKEHVRMHGVGNFELNDGDKDQNRCNICHKQLSRPEHLKAHMRLHLGTLFKCETCQKEFSRLSDLDRHKLVHSGLKQFICIICHKQFSRKDYLKNHMLSHANQKSFECDKCKKRFTYFTNLRNHLHLHIGD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00060529;
90% Identity
iTF_01412510;
80% Identity
iTF_01411720;