Tmol003907.1
Basic Information
- Insect
- Tenebrio molitor
- Gene Symbol
- lola
- Assembly
- GCA_963966145.1
- Location
- OZ014538.1:43446054-43452700[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 23 3.4 2.9e+02 2.8 3.7 1 20 2 21 2 23 0.82 2 23 0.9 77 4.6 1.0 1 21 31 53 31 54 0.96 3 23 0.18 15 6.9 5.7 1 22 55 77 55 80 0.91 4 23 0.031 2.7 9.2 4.6 1 23 85 108 85 108 0.96 5 23 0.00014 0.012 16.6 2.7 3 21 120 138 117 139 0.96 6 23 0.0036 0.31 12.2 0.4 1 23 147 170 147 170 0.93 7 23 0.0024 0.21 12.7 0.5 1 21 198 218 198 219 0.95 8 23 0.033 2.8 9.2 0.1 1 23 227 250 227 250 0.96 9 23 0.0022 0.19 12.9 0.4 1 21 290 310 290 311 0.95 10 23 0.0022 0.19 12.9 0.3 1 23 319 342 319 342 0.97 11 23 0.0033 0.28 12.3 3.2 3 21 356 374 353 375 0.91 12 23 0.00012 0.01 16.8 4.4 1 23 383 406 383 406 0.94 13 23 0.0023 0.19 12.8 0.6 1 21 446 466 446 467 0.95 14 23 0.18 15 6.9 2.3 1 20 475 494 475 496 0.94 15 23 0.0064 0.55 11.4 0.3 5 21 497 513 496 514 0.93 16 23 0.011 0.96 10.6 1.2 3 23 524 545 522 545 0.93 17 23 0.0056 0.48 11.6 0.2 3 23 573 594 571 594 0.95 18 23 0.0017 0.14 13.2 1.9 1 21 627 647 627 648 0.96 19 23 0.0064 0.55 11.4 1.2 1 23 656 679 656 679 0.94 20 23 0.051 4.4 8.6 1.0 2 21 717 736 716 737 0.92 21 23 0.29 25 6.2 3.9 2 23 746 768 746 768 0.97 22 23 0.00056 0.047 14.7 5.0 1 21 781 801 781 802 0.96 23 23 0.0037 0.32 12.1 1.9 1 23 810 833 810 833 0.96
Sequence Information
- Coding Sequence
- ATGTTCTGTTGTGACGTTTGCGGCAAGAAGTACGTGTGGAGCTGCGGCTTGAGCCAGCACAAGAAGTACCAGTGCGGCAGAGAACCGCAGTTCCGGTGTCCGGAGCCCGGATGCACCCACAAGACGCAGCTGAAGGGCAACATGAAGCAGCACATCCGTCATTTCAAGTGCGACCAGTGCTTCAGCAGGAGCTACAAGAACAAGAAGTCGCTTCTGAGGCATCTGCGCTACGAGTGTCACAAGGACCCCACTTTCAGTTGTCCCTACTGTACCCACAAATCCAAATACAAAAACACGCTCCTTTCGCACATTAAACAGCGACATCAGCTGCTCTGTGAACGCAATCGTTGTCATGGCTGTCCAAAGTGCGGTCGCTCATACAGACTGTCTAGTTCCCTTCGAAGACATCTCCGCTACGAATGCCAGAAGGAACCGTCATTCACGTGCGACCATTGTCCGTACAAAGCCAAACAGAAAGTCAATCTTGGAGCGCACATCGCGGCCAAACACCCGCACGCTTTCCGCAAGACCCAAGAAAGACTTATTCTCATTTGTTCACCCAGTCTAACAGTCTCCCTTTTAGATGGGCCCTTCTCGTGCGTGACTTGCGGACGCATCTACAAGGCGAAGAGGTCGCTTTGGAGGCACCAGAAGTACGAGTGTCGGAAAGGACCAGCTTTTAAGTGTCCCGAGTGTCCCTACGGGGCGAGGCGGAAGATGACCGTGGTGGGGCACATGATGAACAAGCACAAGTTGCAAAAGTACGCTTCTGCAGCATCCGCGCTAAAAATGTCTTTCACGTTTGCCCAGAGTGTCGGAGGAAGTATCGGAGTAAGCGGTCGTTGCAGCGCCACCAACGGTGGCCCCTTCGTGTGTATGACTTGCGGACGCATCTACAAGGCGAAAAGGTCGCTTTGGAGGCACCAGAAGTACGAATGTCAGAAAGAACCAGCGTTTAAATGTCCGGTATGTCCCTACAGGGCCAAGCAGAAGTCCACCGTGGTGGGCCACATGATGAGCAAGCACCAGTTCCTCAACCAGCTGAAGCACCAGTCGTACGACTGCTGTGACGTTTGTTTTAAGACGTACAAAACCAAGAAGACGCTCGCTCGCCACAAGAGATACGAGTGCTCTTGCGAGAAGATGTTCGTCTGTCCGGTGTGTCCCAGCAAGTTTAAACGCAGCGACCATCTCAAGCGCCACTACGAACACAAGCACAACTCTGGTCTTCGTCGTTCCGATGCGACGTTTGCGGCAAACGCTACCGCCATTTCGCCTCTTTATGTCGCCACAGGAAGTTCGAGTGCCAAAAGGAAGCCGCATTTAGGTAAACCCTTCCCGTGTGAGCTGTGCGGCAACGCGTACATGCGGAAGAGCGCCTTGAACCACCACAAGAGGTTCTACTGCCAGAAAGAACCCGCCTTCCAGTGCCAACACTGCTCGCACAAAGCCAAGACCAAGTGGAACATGAAGATGCACGTAGCTAAGACTTGTGGTAAATCGTACATGTACAAAACCAACCTGAACCACCACATAAAATTCTACTGCCAGAAGGAGCCGTCCTTCGGGTGCACCCATTGCCCTTACAAGGCGAAAACCAAGGGCAATTTGAAAATCCACTTCAACGGAGTGCACCTCAAGATAAAAAGGACCAGGCATCAGCCCTCGCTGTGGAAGCACGTCAGATACGAGTGCCAAAAGGAGCCGACTTTTGGTTGCTCGTTTTGCCCTTACAAAGCTAAGACGAAAGGCAACTTGCAAATTCACATCAACGGGGTACACCTCAAGCTGAAAAGGACAAAGAAGAGCGGCCAGCCGTATACCTTCAGACTTCAGCGTGAGTGGTTCCGACGTAACTTTGTCATCGTTTCAGAGAGGTTCCAGTGCGGAGCTTGCGGAAAGCGGTACACTAAGCAGCTCTCTCTGCACAAGCACCAGCGGTACGACTGCCAAAAAGAGCCGACTTTTAGCTGTCCGCATTGTCCCTTCAAAGCTAAGAGAAAGTACAACGTGAAGCTGCACGTGAACGGGGTCCACTTGAAGCTGCCGCGGCCCAAACGGTCGAGAAAAGCCGTGCAGAACGTGCTGTGTAGAATTGTTGATTCGTCCTGGAAGCTTGACCGTCACTTGTCCGTTACAGGAAAGTTTCTGTGTGTCACGTGCGGGAGCGTCTACCAGCACAGGAAGACGCTTATGAGACACTTGAGGTACGAGTGTCAGGTGAAACCGAGTGCCAGGTGCGACAGGTGCACTTACGTCGGCAGAAATAAATTGCATCTGCGAGATCATTACAAGCGGAAGCACAAGAAGCGCCTTCCGCAGGCACTTGCTCTTCCAACGTTCACCTGCTCTATGTGCGGACGCCATTACAAGTACAAGAGATCTCTCAAGCACCACATCAAATACGAATGCTTCAAAGAGCCGACGTTCGCTTGTTCGTTCTGTTCTTACAAGTCCAAGACAAAAGGGAACTTGAAGCTGCACACGATGAAGGTGCACTTGACGACGAAGAAGCGCAAGTGA
- Protein Sequence
- MFCCDVCGKKYVWSCGLSQHKKYQCGREPQFRCPEPGCTHKTQLKGNMKQHIRHFKCDQCFSRSYKNKKSLLRHLRYECHKDPTFSCPYCTHKSKYKNTLLSHIKQRHQLLCERNRCHGCPKCGRSYRLSSSLRRHLRYECQKEPSFTCDHCPYKAKQKVNLGAHIAAKHPHAFRKTQERLILICSPSLTVSLLDGPFSCVTCGRIYKAKRSLWRHQKYECRKGPAFKCPECPYGARRKMTVVGHMMNKHKLQKYASAASALKMSFTFAQSVGGSIGVSGRCSATNGGPFVCMTCGRIYKAKRSLWRHQKYECQKEPAFKCPVCPYRAKQKSTVVGHMMSKHQFLNQLKHQSYDCCDVCFKTYKTKKTLARHKRYECSCEKMFVCPVCPSKFKRSDHLKRHYEHKHNSGLRRSDATFAANATAISPLYVATGSSSAKRKPHLGKPFPCELCGNAYMRKSALNHHKRFYCQKEPAFQCQHCSHKAKTKWNMKMHVAKTCGKSYMYKTNLNHHIKFYCQKEPSFGCTHCPYKAKTKGNLKIHFNGVHLKIKRTRHQPSLWKHVRYECQKEPTFGCSFCPYKAKTKGNLQIHINGVHLKLKRTKKSGQPYTFRLQREWFRRNFVIVSERFQCGACGKRYTKQLSLHKHQRYDCQKEPTFSCPHCPFKAKRKYNVKLHVNGVHLKLPRPKRSRKAVQNVLCRIVDSSWKLDRHLSVTGKFLCVTCGSVYQHRKTLMRHLRYECQVKPSARCDRCTYVGRNKLHLRDHYKRKHKKRLPQALALPTFTCSMCGRHYKYKRSLKHHIKYECFKEPTFACSFCSYKSKTKGNLKLHTMKVHLTTKKRK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -