Basic Information

Insect: Temnothorax nylanderi
Gene Symbol: tio
Assembly: GCA_030848795.1
Location: JASTWM010000036.1:340062-347897[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.008 1.2 11.0 0.2 2 22 440 460 439 463 0.90

2 4 0.00097 0.15 13.8 0.4 2 22 554 574 553 577 0.90

3 4 0.00032 0.05 15.4 0.4 2 22 650 670 649 673 0.89

4 4 0.0056 0.87 11.4 1.2 2 23 1220 1242 1219 1242 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.008	1.2	11.0	0.2	2	22	440	460	439	463	0.90
2	4	0.00097	0.15	13.8	0.4	2	22	554	574	553	577	0.90
3	4	0.00032	0.05	15.4	0.4	2	22	650	670	649	673	0.89
4	4	0.0056	0.87	11.4	1.2	2	23	1220	1242	1219	1242	0.96

Sequence Information

Coding Sequence: ATGAGCGGCAGGCAAATACTAGATTCCACGGATTCGCGATCAAGCGCCCGTAGGGGACTCCGAAAGGGGGAGGACGGCGTCGAAGGCTCTGCGCCCGGTACGGACCTCCAAGGCGAGGAGGGCGATTGCGTCGACGAGGATGGTCCCATTAGCCCCAGCGAAAGGGGCTGCGCGCCCGCTGCGAAGGAGGACGAGGATGCCGAGGGAACGGACGAAGAGGACGATGAGGAGGCATCGCCACCTACGCCCCCGCCTTCCGCCACCTCGAGGTTAAACCCGACTATCCTGCGAGACACGGGACCTCCGGATAGGGAGCCAATGAGTCCGCGCTGTCCCTCGAGAGATTCTCGGGAATCATCCGGTCCGGCGACCGGAAGTCCCCCGCCACCTGCTACCAGGAGCAGCGCGAGCCCGGTCAGTCCAAGTAGTATCGTGCCTCTACCCCTTGGAACTCACTCCCTGCTACCACCCCACTCTGCAGCGGTCATGGCGGCGTATCTGCAACAAACCCATCAGCGCCTCCTTCTCGGCCACTCGCCCTTATCGCGTGGCTCGGTATCGCCGCTGGTCTCCTCCTCGTGTTCACCACCAGCCGCCACCCCCGGCCTCCTGGTGTCGCCTACCAGCGTCGGGGAGATCTCGCCGTCAGCGACACCCCTGCCGGCAGTGCTGGACTTTAGCACGAGGAAAACGTCCTCGACCGAGGAGGACGAGGAAGAGCAGATATTAAATCTCAGCAAACCACCTACGCCGTCTTCCTCGACGGAGACGAACAATGGTCCGTTGGATCTTTCGGTACCCAGCAGGAAACGACCCGGCCCGGAAGactcgccgccaccgccaccgcgcAAGTCATCGAGACTGGCCTCCACGACAAGTTCCTCGAGCCATCAGGAAACAGCACCGGGAGTCACGCCATCCGGTTTCGGTAGACCGCCCGTCGTGTCTCCTTGGACGTCTCCAGTGGTGGCTTCGCACTTTCCGTACTTCGCCGCAGCGGTAGCGGCAGCAGCTACTAGTCAGCAGCAGCTTTCGCCGAAGAGCACCAGCGGGGTGGTGGATCATCATCAGCTCTGGAACGGGAAGATGAAGCCGCCAGCCGCGTTAGAAAAGCCCTATCAACCCAGCGAAGCTACAAAGGCACTCGAGAAAATGAGCGAGCTGAGTAAGCTGGGCGGCGAGGATCTTTTCAGGTCGTCTTCCGGAAGCGGTGGTGCCGCGAGTGCCAACGCGCCGGCGACGACGTCCAGCAGTCGTCATAGCGCTTGGCAGTCCCACTGGTTGAATAAAGGTGCCGATCAAGCGAAGGATGTTCTGAAATGCGTGTGGTGCAAACAGAGCTTCCCGACTTTGGCCGCAATGACGACGCACATGAAGGAGGCGAAGCACTGTGGCGTGAACATGCCGGTCCCACCACCAGCGCCAGGAATGCACTCACAACAGACGACGATGCCGACCATACCACCGCCTCAACAGCCGCATCAACCACAGACATCCACCGGTAATATCGGCAGTAACAATTCGGCCACACCTAGCAACAAACAAAGTCCATCCGATTTGAATTTACTGATCAAGGAAACGATGCCGCTGCCGCGGAAGCTCGTGCGAGGTCAGGATGTCTGGTTGGGCAAGGGTGCCGAACAAACGCGGCAGATTCTGAAGTGCATGTGGTGCGGACAGAGCTTCCGCTCGCTAGCCGAGATGACTTCGCATATGCAGCAAACGCAACATTACACAAACATCATCTCTCAAGAACAAATAATATCCTGGAAATCATCGGACGAAAGCAAGGGCGGTAGTGCTACCGGTGCTGCCGGAGGTGGCGGAAGTGTCGCCGGGGGAGGAGGCGGCGCAGGAGGACCGCCGGGAGGAGGGTCCGGACCTCACAGCGGAAACAACGGTGGTCCCGGTCCCGGCGCCACGAGCAGTCACGTTAGCGCCGTGCTGACCTGCAAGGTTTGCGATCAAGCGTTTAGCTCCCTGAAGGAGTTGAGCAATCACATGGTAAAAAATTCGCATTACAAGGAACATATAATGCGCTCGATCACTGAAAGCGGCGGACGTCGACGGCAGACGCGCGAGAAGCGGAAAAAGTCACTGCCCGTGAGGAAATTGCTGGAGCTGGAACGCGCGCAGAACGAATTCAAGAACGGTGACGCTGCCGTCGGTCTAACCCACAGCCTCGGCAAACACGCCGGCAGAATCACGTGCGAGAAGTGCGGCGACAAGATCGAGACTCCGCTTTTTGTGGAGCACATACGTCAATGTATCGGCGCAGGCACGGTCGGCGCCAATCAGCGAAACTTCCTGAAGAACGCGCTCATGTCCAATCATTTGCCCGCGACGTTACCGCCGGCCGAAAGCGGACGTAAGAGCGTCAACGAGGAAACGTCTTCGATATCGTCGAGACACCACCGATCTCCATCTTCGGCCAGCGACGCGACGACACCGGGAAAAGATACTCCTACACCGACCGCTAACGAGACTACCGCTCCGCTAGGTACCTCGCCGTCAGTTTTGAACGCAATAGAGAAGCTCATCGAGAAGAGTTTCGATTCTCGCGTGAGGCATGGCACGCCCGGCTTGCATCACACTCAGCCCGGCGCGCCGATAGGTACGAGCATTCTCAAGCGTTTGGGCATCGACGAGAGCGTGGATTACACGAAACCTCTGGTGGATCCGCAAACGATGAATCTACTACGATCTTATCAACAGCAGCATCAGCAGCAACATTATAACGCCAATGCCGCGGCGAGAAGGGAACGAAGCGGCAGCGAGTCCAGTTCGATATCAGAGCGAGGAAGCGGCAGGACGGATACCATGACACCGGAGAGACGCATGGACCTGTCTAACGCGAGTCACGAAAGACACTCGAGTTCCCGGTCTCATCATCATCGCGTCACTCCCGAGAAGCAGGCCACCCCGTTACCTAGTCGCCATCGTCAAACCACGGAGGAGTCCGGGGACGAGGAGTCGTCTACCGTGGTGGTGAAGAAAGAACCGAGGGACGAGGAGACAGAGGAGCGAGGCGCGACCGAGGAAGAGCAACAGCAGTCGCAGTCGACGAGGGAGGTGTTCGTGAAGAAGGAAATAGTAGACGACTGCAGAGACGAGGAGGATCAGAGTTCCTACAATCACCGACGAAGCAGCATCCATGAGACGCCGGAGGACGGTCGAGAAGTTCTGTCGCCTCGCATGAATCCACCTACGCCCCGGTCGACCAGCCAGGTGGAACAGGTCGCGCGTAGCCCTTGTAGGAACAGCACGAGCAGTCCTACCAGCAGCGACCGATCGGTCACACCGCGGGGTACGCCTGACACTAAGGCATCTAGCAGTCTCGGAGCGCTCTCCTCCATGTTCGACAGCTTGtccggcggtggcggtggtggcggcggtaACAACATCGACTCGCAAGGACGTAAAACAAGTAGCCATCCTCTCGCGGCCTTGCAGAAATTATGCGATAAGACGGAAACGCGAGGTCCCGGCGCTAGCGGAGCCTCGAGATCCGGGGGTGGTTCCGGAGCCAGCACCATCGGTTCGGGCAGCGGTAGCACAGTAGGGGTGACCGGTCCGGGTCCCGGGCCAACGCCAGGTGCCATCTTGGCTTTCAGCTGGGCCTGTAATGATGCCGTGGTCACCGCGGATTCAATAATGAAGTGTGCATTCTGCGATACACCCTTCATTTCGAAAGGTGCATACAGGCACCACCTGTCCAAGATGCACTTTGTCAAGGACGGCGTCATCCCCGATCCATTGACCATCGGTAGGTCGGCGGCAGCAGCCGCAGCAGCAGCCGCCGCGGCGGTTTCCCAGGGCACTTCCGGCGGGCCGAGTCGCAACTCGTCACCGCCGACGTCGCAGCGCAACAAGTCGCCGCCGCTTCCGCAGGCGAACGGCAGCCCGTCGCAGTCAGCGGCCTCACCCCTCGAGGAGAGCCCGCACTCCAAATTTCTCAAGTATACGGAGCTGGCAAAGCAATTGTCCAGCAAATACGTATAG
Protein Sequence: MSGRQILDSTDSRSSARRGLRKGEDGVEGSAPGTDLQGEEGDCVDEDGPISPSERGCAPAAKEDEDAEGTDEEDDEEASPPTPPPSATSRLNPTILRDTGPPDREPMSPRCPSRDSRESSGPATGSPPPPATRSSASPVSPSSIVPLPLGTHSLLPPHSAAVMAAYLQQTHQRLLLGHSPLSRGSVSPLVSSSCSPPAATPGLLVSPTSVGEISPSATPLPAVLDFSTRKTSSTEEDEEEQILNLSKPPTPSSSTETNNGPLDLSVPSRKRPGPEDSPPPPPRKSSRLASTTSSSSHQETAPGVTPSGFGRPPVVSPWTSPVVASHFPYFAAAVAAAATSQQQLSPKSTSGVVDHHQLWNGKMKPPAALEKPYQPSEATKALEKMSELSKLGGEDLFRSSSGSGGAASANAPATTSSSRHSAWQSHWLNKGADQAKDVLKCVWCKQSFPTLAAMTTHMKEAKHCGVNMPVPPPAPGMHSQQTTMPTIPPPQQPHQPQTSTGNIGSNNSATPSNKQSPSDLNLLIKETMPLPRKLVRGQDVWLGKGAEQTRQILKCMWCGQSFRSLAEMTSHMQQTQHYTNIISQEQIISWKSSDESKGGSATGAAGGGGSVAGGGGGAGGPPGGGSGPHSGNNGGPGPGATSSHVSAVLTCKVCDQAFSSLKELSNHMVKNSHYKEHIMRSITESGGRRRQTREKRKKSLPVRKLLELERAQNEFKNGDAAVGLTHSLGKHAGRITCEKCGDKIETPLFVEHIRQCIGAGTVGANQRNFLKNALMSNHLPATLPPAESGRKSVNEETSSISSRHHRSPSSASDATTPGKDTPTPTANETTAPLGTSPSVLNAIEKLIEKSFDSRVRHGTPGLHHTQPGAPIGTSILKRLGIDESVDYTKPLVDPQTMNLLRSYQQQHQQQHYNANAAARRERSGSESSSISERGSGRTDTMTPERRMDLSNASHERHSSSRSHHHRVTPEKQATPLPSRHRQTTEESGDEESSTVVVKKEPRDEETEERGATEEEQQQSQSTREVFVKKEIVDDCRDEEDQSSYNHRRSSIHETPEDGREVLSPRMNPPTPRSTSQVEQVARSPCRNSTSSPTSSDRSVTPRGTPDTKASSSLGALSSMFDSLSGGGGGGGGNNIDSQGRKTSSHPLAALQKLCDKTETRGPGASGASRSGGGSGASTIGSGSGSTVGVTGPGPGPTPGAILAFSWACNDAVVTADSIMKCAFCDTPFISKGAYRHHLSKMHFVKDGVIPDPLTIGRSAAAAAAAAAAAVSQGTSGGPSRNSSPPTSQRNKSPPLPQANGSPSQSAASPLEESPHSKFLKYTELAKQLSSKYV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00452860;
90% Identity: iTF_01477202;
80% Identity: -