Basic Information

Gene Symbol
-
Assembly
GCA_030770215.1
Location
JASTWO010000028.1:146688-147683[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0021 0.32 12.7 0.1 2 23 9 30 8 30 0.97
2 10 0.00037 0.056 15.0 2.8 2 23 43 64 42 64 0.96
3 10 0.0024 0.37 12.5 1.4 1 21 70 90 70 92 0.94
4 10 0.00032 0.049 15.2 2.3 1 23 98 120 98 120 0.98
5 10 0.00037 0.057 15.0 1.6 1 23 127 149 127 149 0.97
6 10 7.5e-05 0.011 17.2 5.3 1 23 160 182 160 182 0.97
7 10 2.8e-07 4.4e-05 24.8 0.3 1 23 191 213 191 213 0.99
8 10 6e-07 9.3e-05 23.8 0.9 1 23 219 241 219 241 0.98
9 10 8.1e-06 0.0012 20.3 5.4 1 23 247 269 247 269 0.98
10 10 0.00033 0.051 15.2 5.9 1 23 275 297 275 297 0.97

Sequence Information

Coding Sequence
ATGCTCACTCACGATAACGTCTTGCAGTGCGAATTCTGCGGTGACAGTTTTGTTTCCGATCAGGATCTTAACTTGCACCTAGAGACGCACGAGTCCCATTCGGAGGGGACACAGGATGAGCAGTTGGTCTGCGAGAATTGCGGCTGCAGCTTCATGACAACGTCGGAGCTGCATGAGCATCAGAAGGAACACGTTTCAGAGGAGTGTTTTAGCTGCGACAGTTGCGACTACGTGACCTCGCGCAGGGAGAGCCTGATCGCTCATGAGCGGTGCCACATATCCAATTACAAATACCAGTGCGAGACATGCGGCGAACAATTCCAGAGCAAGAGCAATTGTCAGGTACATCTGTTGTCGCACGCGCGTGAAGAAAAGCCGTTTCAATGCGACGTGTGTAACGCCACGTTTCGCTATCACCAAGGTCTACGACTGCATGCGAAGCTGCATCAACCGGACTATGTGCCGCCACAGAGGAAACATCACTGCGAGCTGTGCAACAAGCGTTTCTCTCGGAGACAGGTGTTGTTGGTGCACATGAAGACCCACGGCAACGTGGAACCGCAAAACGAGTACGTGTGCACGATTTGCGGCAAGTCCGTGTCAAGCAAAACTTATCTCGCGGTGCATCTGCGCAAGCACACCGGCGAGAAGCCGCATGTTTGCGATATTTGCGGCAAGGGCTTCATCTCACAGAACTACCTGAGTGTGCATCGTCGCACGCACACGGGCGAGAAGCCGCATCAGTGCACGCATTGCAACAAAAGGTTTACTCAACGGACTACGTTGGTAGTGCATCTACGAGGTCACACGGGCGATCGACCTTATCCCTGCACATGCTGTCACAAATCATTTGCTTCGAAAACGATGCTGAACTCGCACTTGAAAACACACGCGAAACAAAGCGCCCGGCAACAACAGGAGCAACAGCAACAAgtacagcagcagcagcaacaagaAGAGTCATTACCCCTCGAAACCGTTACTATAGTGTTGTAA
Protein Sequence
MLTHDNVLQCEFCGDSFVSDQDLNLHLETHESHSEGTQDEQLVCENCGCSFMTTSELHEHQKEHVSEECFSCDSCDYVTSRRESLIAHERCHISNYKYQCETCGEQFQSKSNCQVHLLSHAREEKPFQCDVCNATFRYHQGLRLHAKLHQPDYVPPQRKHHCELCNKRFSRRQVLLVHMKTHGNVEPQNEYVCTICGKSVSSKTYLAVHLRKHTGEKPHVCDICGKGFISQNYLSVHRRTHTGEKPHQCTHCNKRFTQRTTLVVHLRGHTGDRPYPCTCCHKSFASKTMLNSHLKTHAKQSARQQQEQQQQVQQQQQQEESLPLETVTIVL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01523558;
90% Identity
iTF_01408490;
80% Identity
-