Basic Information

Gene Symbol
-
Assembly
GCA_002237135.5
Location
CM026970.3:129679540-129683258[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0011 0.18 13.6 1.6 1 23 114 137 114 137 0.96
2 13 0.00031 0.047 15.4 0.4 3 23 144 165 142 165 0.94
3 13 2.7e-05 0.0042 18.8 4.6 2 23 175 197 174 197 0.93
4 13 6.2e-07 9.6e-05 23.9 4.7 1 23 339 361 339 361 0.97
5 13 2.4e-05 0.0038 18.9 0.2 2 23 364 386 363 386 0.94
6 13 8.7e-05 0.014 17.2 0.7 2 23 393 415 392 415 0.96
7 13 5.4e-06 0.00083 21.0 4.6 1 23 420 442 420 442 0.98
8 13 4e-05 0.0062 18.2 0.2 1 23 447 471 447 471 0.93
9 13 0.0022 0.34 12.8 1.3 3 23 477 497 476 497 0.99
10 13 5.2e-05 0.0081 17.9 1.4 1 23 503 525 503 525 0.98
11 13 2.6e-06 0.00041 21.9 2.5 1 23 531 553 531 553 0.96
12 13 1.8e-06 0.00028 22.4 0.8 1 23 559 581 559 581 0.99
13 13 1.1 1.6e+02 4.3 0.1 1 21 586 606 586 609 0.76

Sequence Information

Coding Sequence
atggatatgaataaaatatgtcGGGTATGCTTGAGGGAAGATCAAGACATGCTATTGATATTTGAAGAAAAGTATACAAATAATGTTGAAGCAAATCTTAGTATAGCAGCAATGTTATcagaaataacaatttataagGTACAACGTTTCGATGAATTACCCCATTTAATCTGTAGTGGTTGTTTTTTGGCTACACAAAATGCATTTGCTTTTAAACGCAGTTGTGAAAAGTCTTACCGGCAGCTTGTCACATTGTTAGGCAATAATGAACTCAATCTCAATTCTAATATCGACGGAAACAGACTTGATAATAGCACTCAAACAGTCGACACCTGCTTGTACCCATGTGAACGGTGCGATGAGAAGTTTTTCACATTTTACGAGCTAAAAagTCATAGAGACAAAGAacataaaggcagtgatatcATTTGTCGATATTGTTCAAAGAGATTTAATCGTATTGGATATTTGAAAACGCATATTGCTATATTTCATCCGGAGATTGGCTTAAGGTCTCATCTCCAATGTCACATATGCAAACGTCAATTTACACGAAGTCAACATCTAAAACGGCATTTAGCTTTACTACATAAGTACAGTGAAGAGAAATGCGATCTGAAGGATGAAAATACGATAGAAGAAAttacGCTTAGTTTTGATAGCAAATTATTCTATCCTGGGTTTAATGATCAAACTgaagacaaaaattttgaatccgGTAGTGATAATGAAAATATAGATTCACAAACTGATGTTTCAAATCTATTACTTCCAAAAAGTGAAGATGAAGATAAAAAACTAGTAacggaattttttaataaaaaccctTCAAGCGGTTTTACGGAAGaaaatacGATAGATCCTACAgaaataaaatctgaaaaacTTCAGCcaacaattgaaaatagtttagATGCATTAGATTTGCCTATAAAACGTAGACGTGGGCGTCCACGAAGAAAAAGTAATACTGCTACTACCACCACCACCACTAGTCCTATtaacgataaaaaatataaatgtagtgAGTGTGACAAACGATTTTCACATGAGAGCAACTTAAAACGTCATAAACTGAACCATGAGATACgctgcaaaatttgttcactgaACTTTTCTAGTCCAGATAACTTGACAGATCACATTCAAGCTACGCATAATGCAACAAAACTATTGAATTGTGAAAACTGTGATGAAATATTTACACGTGATGATCAATTAAAAGAACATTATAAAActaaacataaagaaaaaacacACAAATGTGATAAATGTAACAAAACTTTCAGGACAAAACCATTTCTACAACGGCATCTTGCAACACATGGTAATAAACGTTATGTTTGCAAGGAATGCTTACAGGATTTTAGTAGTAAGGATGACTTGAATTCCCATATAAAGATGGCAGGTCATGATAAGCCATTATTATGTCCAGAGTGTGGTTTACGTTGCAAAACAAGTACTATACTCCTAGTGCATATGAGACGTCATACCGGAGAAAAACcgtttaaatgtaaattttgcaGTAAAGGTTTTCCACGTATGGATGATTTACGGGTACATGAAAGATACCATACAGGTGAAAAATCTCATTTTTGTGAGACGTGCGGTAAAGGatttcaaagaaaatacaatttaacaaTTCACCTACGAGTGCACACTGGTGAAAAACCCTACAAATGTCCACATTGTCAGCAAGCCTTTGCACAAGGGAATGACCTAAAAGCGCATATAAGACGTCACACAGGAGAAAGATTTCGTTGTGATATTTGTGGTGGTGCTTTTCTTCAAGGCTATCAAATCCGTCAACATAAGTTAGCTGAACATGGTATAAAAGATATTCCTCCAACACAACGTGTTGCAAAATTTACATCACGCGAAGCACAAGagaaacaaatacaacaaaatttacaaaaagaaCTTCAGGAAGCCGAGGCTATGAGTGGTAGCACAACAGAGAGTACAAAACTACAATTAGACAGTTCCAGCTAA
Protein Sequence
MDMNKICRVCLREDQDMLLIFEEKYTNNVEANLSIAAMLSEITIYKVQRFDELPHLICSGCFLATQNAFAFKRSCEKSYRQLVTLLGNNELNLNSNIDGNRLDNSTQTVDTCLYPCERCDEKFFTFYELKSHRDKEHKGSDIICRYCSKRFNRIGYLKTHIAIFHPEIGLRSHLQCHICKRQFTRSQHLKRHLALLHKYSEEKCDLKDENTIEEITLSFDSKLFYPGFNDQTEDKNFESGSDNENIDSQTDVSNLLLPKSEDEDKKLVTEFFNKNPSSGFTEENTIDPTEIKSEKLQPTIENSLDALDLPIKRRRGRPRRKSNTATTTTTTSPINDKKYKCSECDKRFSHESNLKRHKLNHEIRCKICSLNFSSPDNLTDHIQATHNATKLLNCENCDEIFTRDDQLKEHYKTKHKEKTHKCDKCNKTFRTKPFLQRHLATHGNKRYVCKECLQDFSSKDDLNSHIKMAGHDKPLLCPECGLRCKTSTILLVHMRRHTGEKPFKCKFCSKGFPRMDDLRVHERYHTGEKSHFCETCGKGFQRKYNLTIHLRVHTGEKPYKCPHCQQAFAQGNDLKAHIRRHTGERFRCDICGGAFLQGYQIRQHKLAEHGIKDIPPTQRVAKFTSREAQEKQIQQNLQKELQEAEAMSGSTTESTKLQLDSSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-