Basic Information

Gene Symbol
-
Assembly
GCA_011170035.1
Location
BLKR01004678.1:37235-39848[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 4e-05 0.029 17.8 0.1 1 23 54 77 54 77 0.95
2 10 5.9e-06 0.0043 20.5 0.2 1 23 96 118 96 118 0.99
3 10 9.7e-07 0.00071 22.9 0.1 1 23 124 146 124 146 0.98
4 10 0.0019 1.4 12.6 0.1 1 23 152 174 152 174 0.96
5 10 7.4e-06 0.0054 20.2 0.2 1 23 180 203 180 203 0.96
6 10 6.5e-05 0.047 17.2 2.7 1 23 210 232 210 232 0.96
7 10 4.7e-05 0.034 17.6 0.3 1 23 238 260 238 260 0.98
8 10 4.3e-07 0.00031 24.0 1.2 1 23 266 288 266 288 0.99
9 10 1.3e-05 0.0091 19.4 4.3 1 23 294 316 292 316 0.98
10 10 7.1e-06 0.0052 20.2 0.9 1 23 322 344 322 344 0.99

Sequence Information

Coding Sequence
ATGTTCACTCGTTtggcgaactgcgcggcggaggcgacatCGGCGGCGCCGGTGAAGGCGGCCGGTGGCAAGAGCCGGTGCCCGTGGCCGCGGGGCCCCGGGGGGCGGGTGGTGCGCGTGGGGGGCGCGGGCGCCCCGCGGCCGGCGCCCAAGCTGTCGCACGCCTGCGCCGACTGCGGCGCGTCCTTCCGCTCCTTGTGGGCGCTGCAGGTGCACGAGCGCAAGGCTCACCCGAAGcccgcgacggtggcggcggcggctgcggctgccgCTGCCCGCGCCACCTACCGCTGCGCCACCTGCGACGGCACCTTCCCCACGGCGTCGGGTCTCAAGAtccacacgcgcacgcacacgggcgagcggcccTTCCCGTGCGAGCTGTGCGGCGCCGCCTTCAGCACGTCGTCCTACCTGTCGGTGCACCGGCGCATccacacgggcgagcggccgcACCGCTGCGCCGCCTGCCCGGCGGCCTTCGCCACCAAGAAGCTGCTGACggagcacgcgcgcgcgcacacgggGGAGCGGCCCTTCGCGTGCGACCTGTGCGGCGAGCGCTTCGCCCGCGCCTACGCGCTGCGCACGCACCGCCTGCGCCAGCACGCCGGCGCGGACCACGCGCACGCCTGCGACCGCTGCCCGGCCACCTTCACGCAGCACAACAGCCTGCTGGTGCACCAGCGCACGCACACGGGCGAGCGCCCCTTCCCCTGCGACCTGTGCGCCTCGGCCTTCAAGAGCAGGTCGGAGCTGAACGTGCACCGCCGCAGCCACACGGGCGAGCGGCCCTTCCGCTGCGAGCTGTGCCCGGCCGCCTTCACCACCAGCTCGCACCTGCTCGTGCACCGCCGCACGCACACGGGCGAGTGCCCCTACTGCTGCGACTTGTGCGGGGAAACCTTCATCACCAGCACCAAGCTCAAGATCCACCGGCGCCgccacaccggggagaagccctaCAAGTGCGACCGGTGCGAGCGCGCGTTCAGGGACGACTCCGGGCTGCGCGCGCACCGCAAGAAGCACACGGAGGGCTGA
Protein Sequence
MFTRLANCAAEATSAAPVKAAGGKSRCPWPRGPGGRVVRVGGAGAPRPAPKLSHACADCGASFRSLWALQVHERKAHPKPATVAAAAAAAAARATYRCATCDGTFPTASGLKIHTRTHTGERPFPCELCGAAFSTSSYLSVHRRIHTGERPHRCAACPAAFATKKLLTEHARAHTGERPFACDLCGERFARAYALRTHRLRQHAGADHAHACDRCPATFTQHNSLLVHQRTHTGERPFPCDLCASAFKSRSELNVHRRSHTGERPFRCELCPAAFTTSSHLLVHRRTHTGECPYCCDLCGETFITSTKLKIHRRRHTGEKPYKCDRCERAFRDDSGLRAHRKKHTEG*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-