Basic Information

Gene Symbol
pita
Assembly
GCA_948473455.1
Location
OX419585.1:8582726-8605773[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.35 25 6.1 0.7 3 23 191 212 189 212 0.93
2 17 0.001 0.074 14.1 0.4 3 23 219 239 218 239 0.97
3 17 0.00023 0.016 16.1 0.6 1 23 245 268 245 268 0.95
4 17 0.57 41 5.4 1.7 2 23 275 296 274 296 0.95
5 17 0.00036 0.026 15.5 0.3 1 20 304 323 304 324 0.95
6 17 7.2e-05 0.0052 17.7 0.5 1 23 335 357 335 357 0.98
7 17 6.3e-05 0.0045 17.9 7.7 1 23 363 386 363 386 0.97
8 17 0.0017 0.12 13.4 0.2 1 23 396 418 396 418 0.95
9 17 0.25 18 6.6 0.1 2 23 424 445 423 445 0.96
10 17 0.19 14 6.9 0.6 1 21 451 471 451 474 0.83
11 17 1.3 92 4.3 2.6 2 23 492 513 491 513 0.94
12 17 0.00036 0.026 15.5 0.3 1 20 521 540 521 541 0.95
13 17 7.2e-05 0.0052 17.7 0.5 1 23 552 574 552 574 0.98
14 17 6.3e-05 0.0045 17.9 7.7 1 23 580 603 580 603 0.97
15 17 0.0017 0.12 13.4 0.2 1 23 613 635 613 635 0.95
16 17 0.25 18 6.6 0.1 2 23 641 662 640 662 0.96
17 17 0.19 14 6.9 0.6 1 21 668 688 668 691 0.83

Sequence Information

Coding Sequence
ATGGAGAATAGGAGAAAAGGTTTATATACTGCAAAAGCGTGCCGCTTTTGTTTATCGCAAGAGGAGCCGCTAACAGGCCTGTTTGATAAGAAACAAGGGTCAAAGAATTCAGTCCCGCTTTCACTGAAAATATTGTCCAGCATCTCTGTAGAGGTCTTTCCTTCTGAAAAAATGCCTCCTTACATTTGCCGCCGCTGCATATTTTTCATGGATGTGGTGTATAACTTTAAGAATGTCTGCCGAGAAGGGGATAAATCTATTCTAGACTTTGTTCAAACTGGCTCTGCGTTGGAACCAGTTGTGTGGCCCCCGTCTCTGGTCAAACTTTTTCGCTATGGATCTAAGCCGGCTCCTGATGTGAATGTAGTAAAGGTTGAAGGGGGAGCCACTGTAGAAGTGTCTCAGGGTGCTTCTGATAGTGAGGGAGATATTGAAAATGTCTATAATGTCCAGATAGGAGATGGAACAGAGGAAGGGACGTCGGCTTGTGTCAAAGTGGTAACCAGCATAGATACTGAAAATTCCACCAAAGAGAGAAAAAAAGATTGTGAGAGCGTGGACTGCTGGGCCTGCGACGAGTGCAACTGCACCTACCCGCTGCAGCAGCTGCTGGAGCTACACAAGATGCAGAAACACCGCGCCCGGAACGTCGCCTGCGAGCTCTGTGACAACAAATTCTTCACCAAGTATGATCTGAACATCCACATGCTGCTGCATTCGAACGAAATGCCGTTCCAATGCGTCGCCTGTGGGAAGCGATTCCGCCGGCTCATATTACTCAAACGACACGAAAAGCTGATTCACTCGGAGCTGCCGCAGCAGAAGTGCCCGCACTGCCCTGCCAGCTTCCTGTCCTCGGAGGAGTGCGAGGCTCACCAGCTGCGGCACCAGCGCCGCGGCGACCGCAAGTTCGCCTGCACGCAATGCGACAAGAGATTCTTCGAGCGCAGCGCTTTAAATAGACACATAGACTGTGTGCACGAGTCTAAGTCCAAAACCATGTATTCCTGCGAGTATTGCCCCGAGCAATTCACATCAATCACGAAGCTTGCGCGGCACGTGCGATCCCACGCCAGCGACAGGCCGTACCCGTGCAAATATTGTGACAAAACGTTTATCAAGTCACATCATTACACAAGACATCTCCGCTACAAGCACGGCTCGGAGGCTCAGCCCCAAGAGGAATTCCGCTGTGAGCAGTGCACGGAGAGCTTCGGCAGCCAGGACGAGCTGATGTACCACTCCGCCATACACGCCACGCAGAACCTCACCTGCCCGCTCTGCCAGGAGAAGTTCCTCAACGTGGACGCCGTCACCGACCACATCAAGTCACACGTCAATGGAATGGAATTTATGTGCGACTTCTGTGAACTAGTATTCACAACTAAGGAGAAGCTCGACTTTCATCTGGAAAATGTGCATGAAGAAGAGCTTCGCAACACAGAGCTGATCCACTCGGAGCTGCCGCAGCAGAAGTGCCCGCACTGCCCTGCCAGCTTCCTGTCCTCGGAGGAGTGCGAGACTCACCAGCTGCGGCACCAGCGACGCGGCGACCGCAAGTTCGCCTGCACGCAATGCGACAAGAGATTCTTCGAGCGCAGCGCTTTAAATAGACACATAGACTGTGTGCACGAGTCTAAGTCCAAAACCATGTATTCCTGCGAGTATTGCCCCGAGCAATTCACATCCATCACGAAGCTTGCGCGGCACGTGCGATCCCACGCCAGCGACAGGCCGTACCCGTGCAAATATTGTGACAAAACGTTTATCAAGTCACATCATTACACAAGACATCTCCGCTACAAGCACGGCTCGGAGGCTCAGCCCCAGGAGGAGTTCCGCTGTGAGCAGTGCACGGAGAGCTTCGGCAGCCAGGACGAGCTGATGTACCACTCCGCCATCCACGCCACGCAGAACCTCACCTGCCCGCTCTGCCAGGAAAAGTTCCTCAACGTGGACGCCGTCACCGACCACATCAAGTCACACGTCAATGGAATGGAATTTATGTGCGACTTCTGTGAACTAGTATTCACAACTAAGGAGAAACTCGACTTTCATTTGGAAAACGTGCATGAAGAAGAGCTTCGCAACACAGAGGAGATGGAACAAGACGAGACTTCAATGGAGATGGAGGAAGAAGATGACGATGAAGATATAAAAGTAAAAGAAGAAGATGATCACATGGTAGTAGAAATCAAGAAACCAAGTGAATTTATGCTTTCAGCAATGGATCAAGACGCAGAAGAGAAAATGAATAATACTAATTCTGAAGAGAGCGAGTCGGAGGGTATGGGCTCAGAGCCGGCAATGGTTCCAGTCCCGCAGGCAGTCGCCGCCGCGCCCCCCGCGCAGCTGCCCCCGCTCACGCGCGCGCCCAGCACCCCCCCCACCGCCACCGCCACGCCGCCCAGGGACGATGCCAGCCAACCTGCTAGCAATAGCCTGACCGCTACAATTCTACGAAAAGCAGAAGAAGTTAAACGCAAAGTACAAGACACCCCACCTCAAGAAAAGAAAGAGAAGCCAAAAACTGAGAGCAGCTCTGGCGCGAGTGATAAATCTCTTCGTCTGCTGGAGAAGGAGTTACAGGAACTGCAAAGGACAAAAAAAAGAGAAGAAAGCACTAAGACACCAGTAAAGACGTTAGAAACTATTCGAGGTAGAGGACGACCGCCGATATACACCTCTACACCAAAACCGAGGTCAGAAGAAAAGAAACCTAGTGTCACCAAATTGACGCCATCTGAAAAGAAAGTGCCAGAGAAGCGAGCCGTTAAAGAAAACAAGAAACCCGAAGAAAGCAAAGAAGCCAAAGTAAACAATGTTAGCGCAAAAGAAAATAAGGAAGAGAGAGATACAAAAACAAGGGAAGATAAAGAAACGAAATCTAAAGAAGACAAAGAAATGAAGGTGAACACTACCAAGGAAGAGAGCAAAGATAAGAGTGTTGTCAAGAATGGAAGCAGCGGCAACAAGAGTTCGGAGGAGCCGGTGCGGCGGTCGTCGCGCCCCTCCAAGGTCAAGGACTATGCCAAGATGGTCAACAACGTCAGAAAAGAAGAACCTTTGCAATCAGACGACGACTCGGAGGAAGATGACGACGACGAAGAGTACGTCGAAGATGATAAACCTGAGGTGCGTCCCAAGGGGCGGCGTGAGACTCCGAAGCCCGCGGCCAGGGTGCCCGCGCTGAAGTCCCCTCCCAGCGCCACGCCCACACGCAAGCGAGGCCGCCCGCGCAAGACTGCGCTGTATGAAATACCAGCGAAAGTCAAGAAAGCTGATGAAGATAGTGAAGAAAAAATGTTGACTGATGACGACACAGAACCCAAAGATAAACTTGACCAAACCGACATAGCTAAGGAAAAGAATACGTCACAAGAAAGTACCAAACTGACAAGTCCCGAAAAAGCACCAAACGTTCTAGTAGCGCCGACTGGACAAACCCTAAAAAAGGTACCAATCAAGGCGCTACCGCCAGGAGTAAAGCCTTTACCATTGCCACATACTGCTAGAACCATCGGAACTACGGAAACATGTGAGATGCAAATAGGGAAGAAAATGGTTAAAGTTCAGAAGATTGTGATGACGAAAGCCGAGGTGGAAGCTATGGCCAAAAAAGGACTCGTAGAAATGAAGGATGGCACTATGGTCCTAAAACCAGGAGTGAAGATACCTTCAGATCCGAGCGCAATCAAATCTACTCTAGTCGGCGACAGCGAGAAGAAAACGAAAGAATCTCCAATTAAACCTGCCCCATCGCGCTGTGAGGTGGAAGACGACATATAA
Protein Sequence
MENRRKGLYTAKACRFCLSQEEPLTGLFDKKQGSKNSVPLSLKILSSISVEVFPSEKMPPYICRRCIFFMDVVYNFKNVCREGDKSILDFVQTGSALEPVVWPPSLVKLFRYGSKPAPDVNVVKVEGGATVEVSQGASDSEGDIENVYNVQIGDGTEEGTSACVKVVTSIDTENSTKERKKDCESVDCWACDECNCTYPLQQLLELHKMQKHRARNVACELCDNKFFTKYDLNIHMLLHSNEMPFQCVACGKRFRRLILLKRHEKLIHSELPQQKCPHCPASFLSSEECEAHQLRHQRRGDRKFACTQCDKRFFERSALNRHIDCVHESKSKTMYSCEYCPEQFTSITKLARHVRSHASDRPYPCKYCDKTFIKSHHYTRHLRYKHGSEAQPQEEFRCEQCTESFGSQDELMYHSAIHATQNLTCPLCQEKFLNVDAVTDHIKSHVNGMEFMCDFCELVFTTKEKLDFHLENVHEEELRNTELIHSELPQQKCPHCPASFLSSEECETHQLRHQRRGDRKFACTQCDKRFFERSALNRHIDCVHESKSKTMYSCEYCPEQFTSITKLARHVRSHASDRPYPCKYCDKTFIKSHHYTRHLRYKHGSEAQPQEEFRCEQCTESFGSQDELMYHSAIHATQNLTCPLCQEKFLNVDAVTDHIKSHVNGMEFMCDFCELVFTTKEKLDFHLENVHEEELRNTEEMEQDETSMEMEEEDDDEDIKVKEEDDHMVVEIKKPSEFMLSAMDQDAEEKMNNTNSEESESEGMGSEPAMVPVPQAVAAAPPAQLPPLTRAPSTPPTATATPPRDDASQPASNSLTATILRKAEEVKRKVQDTPPQEKKEKPKTESSSGASDKSLRLLEKELQELQRTKKREESTKTPVKTLETIRGRGRPPIYTSTPKPRSEEKKPSVTKLTPSEKKVPEKRAVKENKKPEESKEAKVNNVSAKENKEERDTKTREDKETKSKEDKEMKVNTTKEESKDKSVVKNGSSGNKSSEEPVRRSSRPSKVKDYAKMVNNVRKEEPLQSDDDSEEDDDDEEYVEDDKPEVRPKGRRETPKPAARVPALKSPPSATPTRKRGRPRKTALYEIPAKVKKADEDSEEKMLTDDDTEPKDKLDQTDIAKEKNTSQESTKLTSPEKAPNVLVAPTGQTLKKVPIKALPPGVKPLPLPHTARTIGTTETCEMQIGKKMVKVQKIVMTKAEVEAMAKKGLVEMKDGTMVLKPGVKIPSDPSAIKSTLVGDSEKKTKESPIKPAPSRCEVEDDI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-