Timp008789.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Teinopalpus imperialis
Gene Symbol
GLIS1
Assembly
GCA_029286865.1
Location
JAGSMU010000014.1:9071624-9076010[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 0.67 75 4.9 0.0 5 23 320 339 315 339 0.87
2 5 0.71 79 4.9 0.2 8 23 360 375 348 375 0.86
3 5 4.1e-06 0.00046 21.3 2.3 2 23 382 405 382 405 0.96
4 5 6.3e-06 0.0007 20.7 0.9 1 23 411 435 411 435 0.97
5 5 2.6e-06 0.00029 21.9 0.1 1 23 441 465 441 465 0.95

Sequence Information

Coding Sequence
ATGGCGGACTATGATATCATACCTTGTTATGACGACGATGAATTATTTCAAGAGAAAAATGAAAACGTAACCGATCTACACGCTTATTATATGTCACAGTTCAATCTCGAAGTGGAAAATGGGAAGAGTAAAGCAAAAGATAGTTTTAAATACGGCGTGGAAGAAAGCTTCGACTTTGAAGTACTTGATAATTGGGACAACACTgaaaataaaactgattttgAAATGATAGAGGAGGTAATAGATAGTAATATTAACgatcaaaatattaaagaagTTCTATTAGATCTAGATGGAATAGAGTTCGATGAAAATTATAAACCAGAATCTTCGGCGAAGAGCAAGGAAATGGAGAGCATTTCAAACAATGATTATATAGACGATGAATCCCTAATAGATGAACTATGTAGAGAAGATGGAGAATCGTGTATATCTCCGGATATTTTTAACGAagaatatttaaacacaattgCTAACGAAAACCTTCTTCCATCCATAGAAACTGCGTTTTCAAAACGATattgtaactttaataatatagaagAATACAATACTCAAGAATACAACGTTGAAATGACACCGATACCAACGAATCCGCCTGTTATTAATAGCTTAGAGCATTATAGTTATCCTAACAATGTACTTTATAACTTGGATAACGAAAAAAAGTACATTCTACCCGACACCCCAACGAGTTGTACTGAATTCAATTTTAACAGGAACGAAAGGAAAGCGTCCGTATCAGATTCCATAGAAAGCGATGTACAAAGCTCGTGTTACTACGACGAGAATTCAGAAAATTTTGATGAAGACGAACTGTTCATAAATTTAGATGATTTCGGTCTTACCTTTGAAaaagataatgaaattaataatgtgGCTGATAATAGGACCAATAATCGAAACGAACGGAAAGACAAGGAAAGAACTCAAGgtGAACGGGTTTGTTTATGGGAGAACTGCTTGGAGAGGTACCCGAACCAAAACACACTGGTGGAACATATAGAGAGGGCGCATGTCAACACATATAAGGGTGACGAATTTAGCTGTCTCTGGCGAGACTGCGCCCGCGCAAGGAGGCCGTTCAACGCGCGGTACAAGCTTCTAATACACATGCGAGTGCATTCGGGACACAAACCTAATCGATGCCACCACCCCGGATGCGGCAAGGCATTCTCCCGCCTGGAGAACCTGAAGATCCACGTGCGATCGCACACCGGCGAGCGCCCGTACGCCTGTCCAGCGCCGCACTGCCGGAAAGCCTTCTCCAACTCCTCGGACAGGGCTAAGCACCAGAGAACACATTTTAACGctAGACCATACGCATGCGGTGCTGCCGGCTGCGGCAAGCGGTACACCGACCCCTCGTCCCTCCGCAAGCACGTGAAGTCCCACCCCCATATCACCAACGTGCCTCGAGCCTGCATCCCGCCCACCAGGCCCATACGAAGACCCGATCACGAGCAGATGGTACCCAGCTCCCCCGCGAAACTGACAACGCTGAGATGCATCAGAGATAAGCTCACGGTGCCCAAATTACAGAAACTGTAA
Protein Sequence
MADYDIIPCYDDDELFQEKNENVTDLHAYYMSQFNLEVENGKSKAKDSFKYGVEESFDFEVLDNWDNTENKTDFEMIEEVIDSNINDQNIKEVLLDLDGIEFDENYKPESSAKSKEMESISNNDYIDDESLIDELCREDGESCISPDIFNEEYLNTIANENLLPSIETAFSKRYCNFNNIEEYNTQEYNVEMTPIPTNPPVINSLEHYSYPNNVLYNLDNEKKYILPDTPTSCTEFNFNRNERKASVSDSIESDVQSSCYYDENSENFDEDELFINLDDFGLTFEKDNEINNVADNRTNNRNERKDKERTQGERVCLWENCLERYPNQNTLVEHIERAHVNTYKGDEFSCLWRDCARARRPFNARYKLLIHMRVHSGHKPNRCHHPGCGKAFSRLENLKIHVRSHTGERPYACPAPHCRKAFSNSSDRAKHQRTHFNARPYACGAAGCGKRYTDPSSLRKHVKSHPHITNVPRACIPPTRPIRRPDHEQMVPSSPAKLTTLRCIRDKLTVPKLQKL