Basic Information

Gene Symbol
-
Assembly
GCA_944452685.1
Location
CALYBZ010000291.1:203707-213941[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.036 3.5 9.2 0.1 2 23 228 250 227 250 0.90
2 10 0.4 39 5.9 0.0 6 23 259 276 259 276 0.97
3 10 0.00018 0.018 16.4 0.4 1 23 282 305 282 305 0.96
4 10 0.0013 0.13 13.7 4.7 1 23 315 337 315 337 0.99
5 10 2.7e-05 0.0026 19.0 3.6 2 23 344 366 343 366 0.94
6 10 2.7e-05 0.0027 19.0 3.1 1 23 372 394 372 394 0.95
7 10 0.13 13 7.4 0.6 2 23 403 424 402 424 0.97
8 10 8.1e-05 0.0079 17.5 0.9 2 23 430 452 429 452 0.89
9 10 2.2e-05 0.0021 19.3 0.5 2 23 459 480 458 480 0.96
10 10 6.7e-06 0.00065 20.9 1.8 1 23 486 509 486 509 0.98

Sequence Information

Coding Sequence
ATGATTTGTCGTTTATGTTTAAAAGAAATTCCAACTGAATCGTGTATCAAGTTATATGAACAAAAGTTGTGCCTGTCATCTGATTCTATAGAGATGGTGAAACTAATCGACAAACATCTTCAAATCCAAATTAAACATAACGATAATGTATCCACTGTTATTTGCCAAGATTGCAATGATCATTTAGAGGAGTTTCATCGATTTTCGCAACAAGTAGCTGCAAAACAATTAACGCTTCGTAAAGAGTTTTTAAACGTAAATTTAAAAAAAGAATACAATTTTGATGATGGTTGGGACAAAGATGATAAATGTCCAATAGATCTTGAACAGGCTGGTGAGGAAATGACCATTAACTGTCCAATAAATATGTTTAAAAATGAATTGGACAGTGATGAACAAGAGATACCAACGGAAGATTTATTTGATAATGTGATAAGCAATGATGAAAAGGATATCATAGCGCCTGACAGTGTGGCCCCAAATCCGGAATCTAACATATATAATGAACTGTCATCGGATGGGGATGATGATATACCATTAATCAAGTTAAAGTCGGCTAAGAAACCACCTCAAAAAAAGAAAGTTAAGAAAACACCGCCAAAACTTCGCGAATGTAAAGAAAAGAAACCACTTAAAAAGAAATTATCTGCAGAAAAGAAAGTTGCATTGTTAATAGACTTAATATGCGACATTTGCCAAACTCGTGTGGATACATGGAAAGCTCTAAGAGAACATTTTCTGCTGGCACACACCAAAACTCCCTATATTAAGTGCTGTGATATAACTTATCGTAAACCACGAGCTCTAATGGAACACCTTGAGTGGCATAAAAATCCTGACATGTTCAGATGTCAGATTTGCGATAAAAATATGTCTAGCGCTCGTAATTTAACTATACATATTACATCAGAACATCCCGATAAAGCAGATATAATAGAGTTTTACGAGTGTGAGCACTGTTCGAAACGTATTCGCAATTATAACTTATATAAGAAACATTTACGATCACATAACAAAGACACTGAAGTTGAATGTCATATATGCAATAAAAGATTTACATCAGAATACCATTTAGATCGTCATATCAGTAATTTTCATAAGAAAGCACCTCCCCACGTCTGCGATATTTGTGGTCGCACATATAAAAATAAAACCTCATTTAAACGTCATTATGATGAGCATCAAGGCATTGTTTCTAAAGCCGTACAGTGTTCGATTTGCAATACATGGCTAAAGAATGAAGATACGTTACGCTTACATCGTTTCACTCATGAGGAACAAATAACGCCGTGCAACGTTTGTGGCAAAGTGTTTAAAACAAAACGTAGACTATATAGACACAAAGTATACTGGCATACATTGGACACCAATTTGCGATGTAGCTTCTGTGACAAAGTGTTTCGCGAAAAGCGCAATCTTGATGAGCACATGGCCATACATACTGGCGTCCAACTCTATACATGTCCACACTGCGGCAAAGATTCACGTTCGAAATCAAATATGTATGTGCATATTAAAAGGATACATCCAGATGAATGGTGGAAATCGAAAATGGAGCGTCTGAACTTGAAGCCCAAAACTGCAGTCAAGTCCGAGGGCTGTGAATAA
Protein Sequence
MICRLCLKEIPTESCIKLYEQKLCLSSDSIEMVKLIDKHLQIQIKHNDNVSTVICQDCNDHLEEFHRFSQQVAAKQLTLRKEFLNVNLKKEYNFDDGWDKDDKCPIDLEQAGEEMTINCPINMFKNELDSDEQEIPTEDLFDNVISNDEKDIIAPDSVAPNPESNIYNELSSDGDDDIPLIKLKSAKKPPQKKKVKKTPPKLRECKEKKPLKKKLSAEKKVALLIDLICDICQTRVDTWKALREHFLLAHTKTPYIKCCDITYRKPRALMEHLEWHKNPDMFRCQICDKNMSSARNLTIHITSEHPDKADIIEFYECEHCSKRIRNYNLYKKHLRSHNKDTEVECHICNKRFTSEYHLDRHISNFHKKAPPHVCDICGRTYKNKTSFKRHYDEHQGIVSKAVQCSICNTWLKNEDTLRLHRFTHEEQITPCNVCGKVFKTKRRLYRHKVYWHTLDTNLRCSFCDKVFREKRNLDEHMAIHTGVQLYTCPHCGKDSRSKSNMYVHIKRIHPDEWWKSKMERLNLKPKTAVKSEGCE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01177211;
90% Identity
iTF_01074748;
80% Identity
-